protected override async Task Context() { await base.Context(); _compoundCalculationMethod = new OSPSuite.Core.Domain.CalculationMethodCache(); _calculationMethodSnapshot = new CalculationMethodCache(); _categorialParameterIdentificationRunMode = new CategorialParameterIdentificationRunMode { AllTheSame = false }; _categorialParameterIdentificationRunMode.CalculationMethodsCache["C1"] = _compoundCalculationMethod; A.CallTo(() => _calculationMethodMapper.MapToSnapshot(_compoundCalculationMethod)).Returns(_calculationMethodSnapshot); }
public CalculationMethodCache CalculationMethodCacheFor(string compoundName) { if (AllTheSame) { return(AllTheSameSelection); } if (!CalculationMethodsCache.Contains(compoundName)) { CalculationMethodsCache[compoundName] = new CalculationMethodCache(); } return(CalculationMethodsCache[compoundName]); }
protected override Task Context() { _calculationMethodRepository = A.Fake <ICalculationMethodRepository>(); _calculationMethodCategoryRepository = A.Fake <ICalculationMethodCategoryRepository>(); _logger = A.Fake <IOSPSuiteLogger>(); sut = new CalculationMethodCacheMapper(_calculationMethodRepository, _calculationMethodCategoryRepository, _logger); _singleCategory = new CalculationMethodCategory { Name = "Multiple" }; _multipleCategory = new CalculationMethodCategory { Name = "Single" }; _calculationMethodWithMultipleOptions = new CalculationMethod { Name = "CM1", DisplayName = "CM1", Category = _multipleCategory.Name }; _calculationMethodWithSingleOption = new CalculationMethod { Name = "CM2", DisplayName = "CM2", Category = _singleCategory.Name }; _anotherCalculationMethodInMultipleOptions = new CalculationMethod { Name = "Another CM", Category = _multipleCategory.Name }; A.CallTo(() => _calculationMethodRepository.All()).Returns(new[] { _calculationMethodWithMultipleOptions, _anotherCalculationMethodInMultipleOptions, _calculationMethodWithSingleOption, }); _singleCategory.Add(_calculationMethodWithSingleOption); _multipleCategory.Add(_calculationMethodWithMultipleOptions); _multipleCategory.Add(_anotherCalculationMethodInMultipleOptions); _calculationMethodCache = new CalculationMethodCache(); _calculationMethodCache.AddCalculationMethod(_calculationMethodWithMultipleOptions); _calculationMethodCache.AddCalculationMethod(_calculationMethodWithSingleOption); A.CallTo(() => _calculationMethodCategoryRepository.FindBy(_singleCategory.Name)).Returns(_singleCategory); A.CallTo(() => _calculationMethodCategoryRepository.FindBy(_multipleCategory.Name)).Returns(_multipleCategory); return(Task.FromResult(true)); }
public virtual CompoundProperties Clone(ICloneManager cloneManager) { var clone = new CompoundProperties { CalculationMethodCache = CalculationMethodCache.Clone(), Processes = Processes.Clone(cloneManager), ProtocolProperties = ProtocolProperties.Clone(), //do not clone: simply update reference that should be changed if required Compound = Compound }; CompoundGroupSelections.Each(clone.AddCompoundGroupSelection); return(clone); }
protected override ParameterIdentificationRunMode CreateRunMode() { var calculationMethodRepository = IoC.Resolve <ICompoundCalculationMethodRepository>(); _categorialRunMode = new CategorialParameterIdentificationRunMode { AllTheSame = false }; _calculationMethod1 = calculationMethodRepository.All().ElementAt(0); _calculationMethod2 = calculationMethodRepository.All().ElementAt(1); _calculationMethodCache1 = new CalculationMethodCache(); _calculationMethodCache2 = new CalculationMethodCache(); _calculationMethodCache1.AddCalculationMethod(_calculationMethod1); _calculationMethodCache1.AddCalculationMethod(_calculationMethod2); _calculationMethodCache2.AddCalculationMethod(_calculationMethod2); _categorialRunMode.CalculationMethodsCache.Add("Drug1", _calculationMethodCache1); _categorialRunMode.CalculationMethodsCache.Add("Drug2", _calculationMethodCache2); return(_categorialRunMode); }
protected override void Context() { base.Context(); sut.AllTheSame = false; var cacheComp1 = new CalculationMethodCache(); cacheComp1.AddCalculationMethod(_calculationMethod1); cacheComp1.AddCalculationMethod(_calculationMethod2); var cacheComp2 = new CalculationMethodCache(); cacheComp2.AddCalculationMethod(_calculationMethod3); cacheComp2.AddCalculationMethod(_calculationMethod2); sut.CalculationMethodsCache["Comp1"] = cacheComp1; sut.CalculationMethodsCache["Comp2"] = cacheComp2; sut.AllTheSameSelection.AddCalculationMethod(_calculationMethod1); sut.AllTheSameSelection.AddCalculationMethod(_calculationMethod2); sut.AllTheSameSelection.AddCalculationMethod(_calculationMethod3); }
public virtual OriginData Clone() { return(new OriginData { Age = Age, AgeUnit = AgeUnit, Comment = Comment, Height = Height, HeightUnit = HeightUnit, BMI = BMI, BMIUnit = BMIUnit, SpeciesPopulation = SpeciesPopulation, Gender = Gender, Species = Species, SubPopulation = SubPopulation, Weight = Weight, WeightUnit = WeightUnit, GestationalAge = GestationalAge, CalculationMethodCache = CalculationMethodCache.Clone() }); }
public virtual OriginData Clone() { var clone = new OriginData { Age = Age, AgeUnit = AgeUnit, Comment = Comment, Height = Height, HeightUnit = HeightUnit, BMI = BMI, BMIUnit = BMIUnit, SpeciesPopulation = SpeciesPopulation, Gender = Gender, Species = Species, SubPopulation = SubPopulation, Weight = Weight, WeightUnit = WeightUnit, GestationalAge = GestationalAge, CalculationMethodCache = CalculationMethodCache.Clone() }; clone.UpdateValueOriginFrom(ValueOrigin); return(clone); }
private void updateCalculationMethodCache(OSPSuite.Core.Domain.CalculationMethodCache modelCalculationMethodCache, CalculationMethodCache snapshotCalculationMethodCache) { _calculationMethodCacheMapper.UpdateCalculationMethodCache(modelCalculationMethodCache, snapshotCalculationMethodCache, oneCalculationMethodPerCategory: false); }
public OriginData() { CalculationMethodCache = new CalculationMethodCache(); }
public Compound() : base(PKSimBuildingBlockType.Compound) { CalculationMethodCache = new CalculationMethodCache(); }
public ModelProperties() { CalculationMethodCache = new CalculationMethodCache(); }
protected override Task Context() { _calculationMethodCacheMapper = A.Fake <CalculationMethodCacheMapper>(); _processMappingMapper = A.Fake <ProcessMappingMapper>(); _logger = A.Fake <ILogger>(); _project = new PKSimProject(); _calculationMethodSnapshot = new CalculationMethodCache(); sut = new CompoundPropertiesMapper(_calculationMethodCacheMapper, _processMappingMapper, _logger); _compoundGroupSelectionOneAlternative = new CompoundGroupSelection { AlternativeName = "ALT1", GroupName = "ALTERNATIVE_GROUP_1" }; _compoundGroupSelectionTwoAlternatives = new CompoundGroupSelection { AlternativeName = "ALT2", GroupName = "ALTERNATIVE_GROUP_2" }; _compound = new Compound { Name = "COMP", }; _protocol = new SimpleProtocol { Name = "PROTOCOL" }; _parameterAlternativeGroupWithOneAlternative = new ParameterAlternativeGroup { Name = _compoundGroupSelectionOneAlternative.GroupName }; _parameterAlternativeGroupWithTwoAlternatives = new ParameterAlternativeGroup { Name = _compoundGroupSelectionTwoAlternatives.GroupName }; _parameterAlternativeGroupWithTwoAlternatives.AddAlternative(new ParameterAlternative { Name = "ALT1" }); _parameterAlternativeGroupWithTwoAlternatives.AddAlternative(new ParameterAlternative { Name = "ALT2" }); _compound.AddParameterAlternativeGroup(_parameterAlternativeGroupWithOneAlternative); _compound.AddParameterAlternativeGroup(_parameterAlternativeGroupWithTwoAlternatives); _compoundProperties = new Model.CompoundProperties(); _compoundProperties.AddCompoundGroupSelection(_compoundGroupSelectionOneAlternative); _compoundProperties.AddCompoundGroupSelection(_compoundGroupSelectionTwoAlternatives); _compoundProperties.Compound = _compound; _enzymaticProcess = new EnzymaticProcess { Name = "EnzymaticProcess" }; _anotherEnzymaticProcess = new EnzymaticProcess { Name = "AnotherEnzymaticProcess", MoleculeName = "CYP3A4" }; _specificBindingProcess = new SpecificBindingPartialProcess { Name = "SpecificBinding" }; _gfrTransportProcess = new SystemicProcess { Name = "Transport", SystemicProcessType = SystemicProcessTypes.GFR }; _hepaticEnzymaticProcess = new SystemicProcess { Name = "Plasma Clearance", SystemicProcessType = SystemicProcessTypes.Hepatic }; _compound.AddProcess(_enzymaticProcess); _compound.AddProcess(_specificBindingProcess); _compound.AddProcess(_gfrTransportProcess); _compound.AddProcess(_hepaticEnzymaticProcess); _enzymaticPartialProcessSelection = new EnzymaticProcessSelection { ProcessName = _enzymaticProcess.Name }; _noEnzymaticSystemicProcessSelection = new SystemicProcessSelection { ProcessType = SystemicProcessTypes.Hepatic }; _specificBindingPartialProcessSelection = new ProcessSelection { ProcessName = _specificBindingProcess.Name }; _transportSystemicProcessSelection = new SystemicProcessSelection { ProcessName = _gfrTransportProcess.Name, ProcessType = _gfrTransportProcess.SystemicProcessType, }; _noEnzymaticPartialProcessSelection = new EnzymaticProcessSelection { MoleculeName = _anotherEnzymaticProcess.MoleculeName }; _compoundProperties.Processes.MetabolizationSelection.AddPartialProcessSelection(_enzymaticPartialProcessSelection); _compoundProperties.Processes.MetabolizationSelection.AddPartialProcessSelection(_noEnzymaticPartialProcessSelection); _compoundProperties.Processes.MetabolizationSelection.AddSystemicProcessSelection(_noEnzymaticSystemicProcessSelection); _compoundProperties.Processes.SpecificBindingSelection.AddPartialProcessSelection(_specificBindingPartialProcessSelection); _compoundProperties.Processes.TransportAndExcretionSelection.AddSystemicProcessSelection(_transportSystemicProcessSelection); _snapshotProcess1 = new CompoundProcessSelection { Name = _enzymaticPartialProcessSelection.ProcessName }; _snapshotProcess2 = new CompoundProcessSelection { Name = _specificBindingPartialProcessSelection.ProcessName }; _snapshotProcess3 = new CompoundProcessSelection { Name = _transportSystemicProcessSelection.ProcessName }; _snapshotProcess4 = new CompoundProcessSelection { SystemicProcessType = _noEnzymaticSystemicProcessSelection.ProcessType.SystemicProcessTypeId.ToString() }; _snapshotProcess5 = new CompoundProcessSelection { MoleculeName = _noEnzymaticPartialProcessSelection.MoleculeName }; _formulation = new Formulation { Id = "123456" }; _compoundProperties.ProtocolProperties.Protocol = _protocol; _compoundProperties.ProtocolProperties.AddFormulationMapping(new FormulationMapping { FormulationKey = "F1", TemplateFormulationId = _formulation.Id }); _project.AddBuildingBlock(_formulation); A.CallTo(() => _calculationMethodCacheMapper.MapToSnapshot(_compoundProperties.CalculationMethodCache)).Returns(_calculationMethodSnapshot); A.CallTo(() => _processMappingMapper.MapToSnapshot(_enzymaticPartialProcessSelection)).Returns(_snapshotProcess1); A.CallTo(() => _processMappingMapper.MapToSnapshot(_specificBindingPartialProcessSelection)).Returns(_snapshotProcess2); A.CallTo(() => _processMappingMapper.MapToSnapshot(_transportSystemicProcessSelection)).Returns(_snapshotProcess3); A.CallTo(() => _processMappingMapper.MapToSnapshot(_noEnzymaticSystemicProcessSelection)).Returns(_snapshotProcess4); A.CallTo(() => _processMappingMapper.MapToSnapshot(_noEnzymaticPartialProcessSelection)).Returns(_snapshotProcess5); A.CallTo(() => _processMappingMapper.MapToModel(_snapshotProcess1, _enzymaticProcess)).Returns(_enzymaticPartialProcessSelection); A.CallTo(() => _processMappingMapper.MapToModel(_snapshotProcess2, _specificBindingProcess)).Returns(_specificBindingPartialProcessSelection); A.CallTo(() => _processMappingMapper.MapToModel(_snapshotProcess3, _gfrTransportProcess)).Returns(_transportSystemicProcessSelection); A.CallTo(() => _processMappingMapper.MapToModel(_snapshotProcess4, A <NotSelectedSystemicProcess> ._)).Returns(_noEnzymaticSystemicProcessSelection); A.CallTo(() => _processMappingMapper.MapToModel(_snapshotProcess5, A <EnzymaticProcess> ._)).Returns(_noEnzymaticPartialProcessSelection); return(_completed); }
public OriginData() { CalculationMethodCache = new CalculationMethodCache(); ValueOrigin = new ValueOrigin(); }