Пример #1
0
        public void SetDerivedParameters(VariantCallingParameters varcallParameters)
        {
            //SetDerivedParameters these according to ploidy model.
            //tjd: I WISH we just never crushed vcfs... Crushing is apparently preffered by germline customers.
            if ((varcallParameters.PloidyModel == PloidyModel.DiploidByThresholding) ||
                (varcallParameters.PloidyModel == PloidyModel.DiploidByAdaptiveGT))
            {
                AllowMultipleVcfLinesPerLoci = false;
            }
            else
            {
                AllowMultipleVcfLinesPerLoci = true;
            }

            // override them if desired
            if (ForceCrush.HasValue)
            {
                AllowMultipleVcfLinesPerLoci = !((bool)ForceCrush);
            }

            //if we have the posteriors data from the adaptive GT model, lets provide it!
            if (varcallParameters.PloidyModel == PloidyModel.DiploidByAdaptiveGT)
            {
                ReportGp = true;
            }
        }
Пример #2
0
        public void SetDerivedParameters(VariantCallingParameters varcallParameters)
        {
            //SetDerivedParameters these accoding to ploidy model
            if (varcallParameters.PloidyModel == PloidyModel.Diploid)
            {
                AllowMultipleVcfLinesPerLoci = false;
            }
            else
            {
                AllowMultipleVcfLinesPerLoci = true;
            }

            // override them if desired
            if (ForceCrush.HasValue)
            {
                AllowMultipleVcfLinesPerLoci = !((bool)ForceCrush);
                return;
            }
        }
Пример #3
0
 public static int GetNoiseLevelUsedForQScoring(
     VariantCallingParameters varCallingParameters, BamFilterParameters bamFilterParameters)
 {
     return(varCallingParameters.ForcedNoiseLevel == -1 ? bamFilterParameters.MinimumBaseCallQuality : varCallingParameters.ForcedNoiseLevel);
 }