Exemplo n.º 1
0
        private void ExecuteBackground()
        {
            try
            {
                ProteinMatchTypes matchTypesRemaining = Settings.MatchTypes;
                using (var proteomeDb = ProteomeDb.OpenProteomeDb(Settings.ProteomeDbPath.FilePath, CancellationToken))
                    using (var session = proteomeDb.OpenStatelessSession(false))
                    {
                        if (matchTypesRemaining.Contains(ProteinMatchType.sequence) && IsAminoAcidSequence(Settings.SearchText))
                        {
                            AddProteinMatches(session, () => proteomeDb.GetDigestion()
                                              .GetProteinIdsThatMightHaveSequence(session, new[] { Settings.SearchText }));
                        }
                        matchTypesRemaining = matchTypesRemaining.Except(ProteinMatchType.sequence);

                        if (DoMatching)
                        {
                            string pattern = @"%" + Settings.SearchText + @"%";
                            if (Settings.SearchText.Length < MIN_FREE_SEARCH_LENGTH)
                            {
                                // That could cast a pretty wide net - only match to beginning of keywords, and not to description or species
                                pattern             = Settings.SearchText + @"%";
                                matchTypesRemaining = matchTypesRemaining.Except(ProteinMatchType.description, ProteinMatchType.species);
                            }

                            var exprLike = new List <string>();
                            foreach (ProteinMatchType matchType in matchTypesRemaining)
                            {
                                exprLike.Add(String.Format(@"pn.{0} LIKE :expr", ProteinMatchTypeDbFieldName(matchType)));
                            }

                            String hql = @"SELECT distinct pn.Protein FROM " + typeof(DbProteinName) + @" pn "
                                         // ReSharper disable LocalizableElement
                                         + String.Format("\nWHERE {0}", String.Join(" OR ", exprLike))
                                         + "\nORDER BY pn.IsPrimary DESC, pn.Name";
                            // ReSharper restore LocalizableElement
                            IQuery query = session.CreateQuery(hql).SetParameter(@"expr", pattern);
                            query.SetMaxResults(MaxResults);
                            AddProteinMatches(session, () =>
                            {
                                return(query.List <DbProtein>()
                                       .Where(dbProtein => null != dbProtein)
                                       .Select(dbProtein => dbProtein.Id.Value));
                            });
                        }
                    }
            }
            catch (Exception exception)
            {
                if (CancellationToken.IsCancellationRequested)
                {
                    return;
                }
                Trace.TraceError(@"Unhandled exception: {0}", exception);
            }
        }
Exemplo n.º 2
0
        public static string TextForMatchTypes(this ProteinMetadata p, ProteinMatchTypes types)
        {
            if (types.IsSingleton(ProteinMatchType.sequence))
            {
                return(null);
            }

            var results = new List <string>();

            if (types.Contains(ProteinMatchType.name))
            {
                results.Add(p.Name ?? String.Empty);
            }
            if (types.Contains(ProteinMatchType.accession))
            {
                results.Add(p.Accession ?? String.Empty);
            }
            if (types.Contains(ProteinMatchType.preferredName))
            {
                results.Add(p.PreferredName ?? String.Empty);
            }
            if (types.Contains(ProteinMatchType.gene))
            {
                results.Add(p.Gene ?? String.Empty);
            }
            if (types.Contains(ProteinMatchType.species))
            {
                results.Add(p.Species ?? String.Empty);
            }
            if (types.Contains(ProteinMatchType.description)) // put this last, as it likely contains the others
            {
                results.Add(p.Description ?? String.Empty);
            }
            if (results.Count > 0)
            {
                return(String.Join(@" ", results));
            }

            return(null);
        }
Exemplo n.º 3
0
 private static bool Matches(ProteinMetadata proteinMetadata, ProteinMatchType matchType, string ltext)
 {
     return(ContainsLowerCase(proteinMetadata.TextForMatchTypes(ProteinMatchTypes.Singleton(matchType)), ltext));
 }
Exemplo n.º 4
0
 public ProteinMatchSettings(ProteomeDbPath proteomeDbPath, ProteinMatchTypes proteinMatchTypes, String searchText)
 {
     ProteomeDbPath = proteomeDbPath;
     MatchTypes     = proteinMatchTypes;
     SearchText     = searchText;
 }