public override void Render()
{
this.m_TemplateName = @"\\CFileServer\Documents\ReportTemplates\XmlTemplates\ComprehensiveColonCancerProfile.1.xml";
this.OpenTemplate();
this.SetDemographicsV2();
this.SetReportDistribution();
ComprehensiveColonCancerProfile comprehensiveColonCancerProfile = (ComprehensiveColonCancerProfile)this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_PanelSetOrder.ReportNo);
ComprehensiveColonCancerProfileResult comprehensiveColonCancerProfileResult = new ComprehensiveColonCancerProfileResult(this.m_AccessionOrder, comprehensiveColonCancerProfile);
base.ReplaceText("report_interpretation", comprehensiveColonCancerProfile.Interpretation);
base.ReplaceText("ajcc_stage", comprehensiveColonCancerProfileResult.PanelSetOrderSurgical.AJCCStage);
this.SetSpecimen(comprehensiveColonCancerProfileResult);
this.SetIHC(comprehensiveColonCancerProfileResult);
this.SetMolecularResults(comprehensiveColonCancerProfileResult);
base.ReplaceText("pathologist_signature", comprehensiveColonCancerProfile.Signature);
this.SaveReport();
}
public ComprehensiveColonCancerProfileResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
ComprehensiveColonCancerProfile comprehensiveColonCancerProfile)
{
this.m_SpecimenOrder = accessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(comprehensiveColonCancerProfile.OrderedOnId);
this.m_PanelSetOrderSurgical = (YellowstonePathology.Business.Test.Surgical.SurgicalTestOrder)accessionOrder.PanelSetOrderCollection.GetSurgical();
this.m_SurgicalSpecimen = this.m_PanelSetOrderSurgical.SurgicalSpecimenCollection.GetBySpecimenOrderId(this.m_SpecimenOrder.SpecimenOrderId);
bool restrictToOrderedOn = !comprehensiveColonCancerProfile.IncludeTestsPerformedOnOtherBlocks;
YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_LSEIHCIsOrdered = true;
this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
this.m_IHCResult = YellowstonePathology.Business.Test.LynchSyndrome.IHCResult.CreateResultFromResultCode(this.m_PanelSetOrderLynchSyndromeIHC.ResultCode);
}
YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_MLHIsOrdered = true;
this.m_PanelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_BRAFV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_BRAFV600EKIsOrdered = true;
this.m_BRAFV600EKTestOrder = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_KRASStandardTest = new YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_KRASStandardIsOrdered = true;
this.m_KRASStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_KRASExon23MutationTest = new KRASExon23Mutation.KRASExon23MutationTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_KRASExon23MutationIsOrdered = true;
this.m_KRASExon23MutationTestOrder = (KRASExon23Mutation.KRASExon23MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_KRASExon4MutationTest = new KRASExon4Mutation.KRASExon4MutationTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_KRASExon4MutationIsOrdered = true;
this.m_KRASExon4MutationTestOrder = (KRASExon4Mutation.KRASExon4MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_NRASMutationAnalysisTest = new NRASMutationAnalysis.NRASMutationAnalysisTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_NRASMutationAnalysisIsOrdered = true;
this.m_NRASMutationAnalysisTestOrder = (NRASMutationAnalysis.NRASMutationAnalysisTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_RASRAFPanelTest = new RASRAFPanel.RASRAFPanelTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_RASRAFIsOrdered = true;
this.m_RASRAFPanelTestOrder = (RASRAFPanel.RASRAFPanelTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
}
public ComprehensiveColonCancerProfileResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
ComprehensiveColonCancerProfile comprehensiveColonCancerProfile)
{
this.m_SpecimenOrder = accessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(comprehensiveColonCancerProfile.OrderedOnId);
this.m_PanelSetOrderSurgical = (YellowstonePathology.Business.Test.Surgical.SurgicalTestOrder)accessionOrder.PanelSetOrderCollection.GetSurgical();
this.m_SurgicalSpecimen = this.m_PanelSetOrderSurgical.SurgicalSpecimenCollection.GetBySpecimenOrderId(this.m_SpecimenOrder.SpecimenOrderId);
bool restrictToOrderedOn = !comprehensiveColonCancerProfile.IncludeTestsPerformedOnOtherBlocks;
YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_LSEIHCIsOrdered = true;
this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
this.m_IHCResult = YellowstonePathology.Business.Test.LynchSyndrome.IHCResult.CreateResultFromResultCode(this.m_PanelSetOrderLynchSyndromeIHC.ResultCode);
}
else
{
YellowstonePathology.Business.Domain.PatientHistory patientHistory = YellowstonePathology.Business.Gateway.AccessionOrderGateway.GetPatientHistory(accessionOrder.PatientId);
if(patientHistory.PanelSetIdExists(102) == true)
{
YellowstonePathology.Business.Domain.PatientHistoryResult patientHistoryResult = patientHistory.GetByPanelSetId(102);
YellowstonePathology.Business.Test.AccessionOrder lseIHCAccessionOrder = Business.Persistence.DocumentGateway.Instance.GetAccessionOrderByMasterAccessionNo(patientHistoryResult.MasterAccessionNo);
this.m_LSEIHCIsOrdered = true;
this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)lseIHCAccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
this.m_IHCResult = YellowstonePathology.Business.Test.LynchSyndrome.IHCResult.CreateResultFromResultCode(this.m_PanelSetOrderLynchSyndromeIHC.ResultCode);
}
}
YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_MLHIsOrdered = true;
this.m_PanelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_BRAFV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_BRAFV600EKIsOrdered = true;
this.m_BRAFV600EKTestOrder = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_KRASStandardTest = new YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_KRASStandardIsOrdered = true;
this.m_KRASStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_KRASExon23MutationTest = new KRASExon23Mutation.KRASExon23MutationTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_KRASExon23MutationIsOrdered = true;
this.m_KRASExon23MutationTestOrder = (KRASExon23Mutation.KRASExon23MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_KRASExon4MutationTest = new KRASExon4Mutation.KRASExon4MutationTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_KRASExon4MutationIsOrdered = true;
this.m_KRASExon4MutationTestOrder = (KRASExon4Mutation.KRASExon4MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_NRASMutationAnalysisTest = new NRASMutationAnalysis.NRASMutationAnalysisTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_NRASMutationAnalysisIsOrdered = true;
this.m_NRASMutationAnalysisTestOrder = (NRASMutationAnalysis.NRASMutationAnalysisTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_RASRAFPanelTest = new RASRAFPanel.RASRAFPanelTest();
if(accessionOrder.PanelSetOrderCollection.Exists(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_RASRAFIsOrdered = true;
this.m_RASRAFPanelTestOrder = (RASRAFPanel.RASRAFPanelTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_SurgicalSpecimenCollection = new YellowstonePathology.Business.Test.Surgical.SurgicalSpecimenCollection();
foreach (YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder in accessionOrder.SpecimenOrderCollection)
{
YellowstonePathology.Business.Test.Surgical.SurgicalSpecimen surgicalSpecimen = this.m_PanelSetOrderSurgical.SurgicalSpecimenCollection.GetBySpecimenOrderId(specimenOrder.SpecimenOrderId);
if (surgicalSpecimen != null)
{
this.m_SurgicalSpecimenCollection.Add(surgicalSpecimen);
}
}
this.m_PanelSetOrderLynchSyndromeIHCCollection = new Collection<LynchSyndrome.PanelSetOrderLynchSyndromeIHC>();
this.m_MolecularTestOrderCollection = new PanelSetOrderCollection();
foreach(YellowstonePathology.Business.Test.PanelSetOrder panelSetOrder in accessionOrder.PanelSetOrderCollection)
{
if(panelSetOrder is YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)
{
this.m_PanelSetOrderLynchSyndromeIHCCollection.Add((YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)panelSetOrder);
}
else
{
if(panelSetOrder is LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis ||
panelSetOrder is KRASStandard.KRASStandardTestOrder ||
panelSetOrder is KRASExon23Mutation.KRASExon23MutationTestOrder ||
panelSetOrder is KRASExon4Mutation.KRASExon4MutationTestOrder ||
panelSetOrder is BRAFV600EK.BRAFV600EKTestOrder ||
panelSetOrder is NRASMutationAnalysis.NRASMutationAnalysisTestOrder ||
panelSetOrder is RASRAFPanel.RASRAFPanelTestOrder)
{
this.m_MolecularTestOrderCollection.Add(panelSetOrder);
}
}
}
}
public ComprehensiveColonCancerProfileResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
ComprehensiveColonCancerProfile comprehensiveColonCancerProfile)
{
this.m_SpecimenOrder = accessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(comprehensiveColonCancerProfile.OrderedOnId);
this.m_PanelSetOrderSurgical = (YellowstonePathology.Business.Test.Surgical.SurgicalTestOrder)accessionOrder.PanelSetOrderCollection.GetSurgical();
this.m_SurgicalSpecimen = this.m_PanelSetOrderSurgical.SurgicalSpecimenCollection.GetBySpecimenOrderId(this.m_SpecimenOrder.SpecimenOrderId);
bool restrictToOrderedOn = !comprehensiveColonCancerProfile.IncludeTestsPerformedOnOtherBlocks;
YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_LSEIHCIsOrdered = true;
this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
this.m_IHCResult = YellowstonePathology.Business.Test.LynchSyndrome.IHCResult.CreateResultFromResultCode(this.m_PanelSetOrderLynchSyndromeIHC.ResultCode);
}
YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_MLHIsOrdered = true;
this.m_PanelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_BRAFV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_BRAFV600EKIsOrdered = true;
this.m_BRAFV600EKTestOrder = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_KRASStandardTest = new YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_KRASStandardIsOrdered = true;
this.m_KRASStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_KRASExon23MutationTest = new KRASExon23Mutation.KRASExon23MutationTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_KRASExon23MutationIsOrdered = true;
this.m_KRASExon23MutationTestOrder = (KRASExon23Mutation.KRASExon23MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_KRASExon4MutationTest = new KRASExon4Mutation.KRASExon4MutationTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_KRASExon4MutationIsOrdered = true;
this.m_KRASExon4MutationTestOrder = (KRASExon4Mutation.KRASExon4MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_NRASMutationAnalysisTest = new NRASMutationAnalysis.NRASMutationAnalysisTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_NRASMutationAnalysisIsOrdered = true;
this.m_NRASMutationAnalysisTestOrder = (NRASMutationAnalysis.NRASMutationAnalysisTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_RASRAFPanelTest = new RASRAFPanel.RASRAFPanelTest();
if(accessionOrder.PanelSetOrderCollection.Exists(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_RASRAFIsOrdered = true;
this.m_RASRAFPanelTestOrder = (RASRAFPanel.RASRAFPanelTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
}
public override void Render()
{
this.m_TemplateName = @"\\CFileServer\Documents\ReportTemplates\XmlTemplates\ComprehensiveColonCancerProfile.1.xml";
this.OpenTemplate();
this.SetDemographicsV2();
this.SetReportDistribution();
ComprehensiveColonCancerProfile comprehensiveColonCancerProfile = (ComprehensiveColonCancerProfile)this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_PanelSetOrder.ReportNo);
ComprehensiveColonCancerProfileResult comprehensiveColonCancerProfileResult = new ComprehensiveColonCancerProfileResult(this.m_AccessionOrder, comprehensiveColonCancerProfile);
YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(comprehensiveColonCancerProfile.OrderedOnId);
YellowstonePathology.Business.Test.AliquotOrder aliquotOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetAliquotOrder(comprehensiveColonCancerProfile.OrderedOnId);
string specimenDescription = specimenOrder.Description;
if (aliquotOrder != null)
{
specimenDescription += ": " + aliquotOrder.Label;
}
base.ReplaceText("report_interpretation", comprehensiveColonCancerProfile.Interpretation);
base.ReplaceText("specimen_description", specimenDescription);
base.ReplaceText("surgical_reportno", comprehensiveColonCancerProfileResult.PanelSetOrderSurgical.ReportNo);
base.ReplaceText("specimen_diagnosis", comprehensiveColonCancerProfileResult.SurgicalSpecimen.Diagnosis);
base.ReplaceText("ajcc_stage", comprehensiveColonCancerProfileResult.PanelSetOrderSurgical.AJCCStage);
if (comprehensiveColonCancerProfileResult.IHCResult != null)
{
base.ReplaceText("mlh1_result", comprehensiveColonCancerProfileResult.IHCResult.MLH1Result.Description);
base.ReplaceText("msh2_result", comprehensiveColonCancerProfileResult.IHCResult.MSH2Result.Description);
base.ReplaceText("msh6_result", comprehensiveColonCancerProfileResult.IHCResult.MSH6Result.Description);
base.ReplaceText("pms2_result", comprehensiveColonCancerProfileResult.IHCResult.PMS2Result.Description);
}
else
{
base.ReplaceText("mlh1_result", "Not Included");
base.ReplaceText("msh2_result", "Not Included");
base.ReplaceText("msh6_result", "Not Included");
base.ReplaceText("pms2_result", "Not Included");
}
if (comprehensiveColonCancerProfileResult.PanelSetOrderLynchSyndromeIHC != null)
{
base.ReplaceText("ihc_reportno", comprehensiveColonCancerProfileResult.PanelSetOrderLynchSyndromeIHC.ReportNo);
}
else
{
base.ReplaceText("ihc_reportno", "Not Included");
}
if (comprehensiveColonCancerProfileResult.RASRAFIsOrdered == true)
{
base.ReplaceText("braf_result", comprehensiveColonCancerProfileResult.RASRAFTestOrder.BRAFResult);
base.ReplaceText("braf_reportno", comprehensiveColonCancerProfile.ReportNo);
base.ReplaceText("kras_result", comprehensiveColonCancerProfileResult.RASRAFTestOrder.KRASResult);
base.ReplaceText("kras_reportno", comprehensiveColonCancerProfile.ReportNo);
base.ReplaceText("nras_result", comprehensiveColonCancerProfileResult.RASRAFTestOrder.NRASResult);
base.ReplaceText("nras_reportno", comprehensiveColonCancerProfile.ReportNo);
base.ReplaceText("hras_result", comprehensiveColonCancerProfileResult.RASRAFTestOrder.HRASResult);
base.ReplaceText("hras_reportno", comprehensiveColonCancerProfile.ReportNo);
}
if (comprehensiveColonCancerProfileResult.PanelSetOrderMLH1MethylationAnalysis != null)
{
base.ReplaceText("mlh1promoter_result", comprehensiveColonCancerProfileResult.PanelSetOrderMLH1MethylationAnalysis.Result);
base.ReplaceText("mlh1promoter_reportno", comprehensiveColonCancerProfileResult.PanelSetOrderMLH1MethylationAnalysis.ReportNo);
}
else
{
this.DeleteRow("mlh1promoter_result");
}
/*
* if (comprehensiveColonCancerProfileResult.KRASStandardIsOrderd == true)
* {
* base.ReplaceText("kras_result", comprehensiveColonCancerProfileResult.KRASStandardTestOrder.Result);
* base.ReplaceText("kras_report_no", comprehensiveColonCancerProfileResult.KRASStandardTestOrder.ReportNo);
* }
* else
* {
* this.DeleteRow("kras_result");
* }
*
* if (comprehensiveColonCancerProfileResult.BRAFV600EKIsOrdered == true)
* {
* base.ReplaceText("braf_result", comprehensiveColonCancerProfileResult.BRAFV600EKTestOrder.Result);
* base.ReplaceText("braf_report_no", comprehensiveColonCancerProfileResult.BRAFV600EKTestOrder.ReportNo);
* }
* else
* {
* this.DeleteRow("braf_result");
* }
*
* if (comprehensiveColonCancerProfileResult.KRASExon23MutationIsOrdered == true)
* {
* base.ReplaceText("kras23_result", comprehensiveColonCancerProfileResult.KRASExon23MutationTestOrder.Result);
* base.ReplaceText("kras23_report_no", comprehensiveColonCancerProfileResult.KRASExon23MutationTestOrder.ReportNo);
* }
* else
* {
* this.DeleteRow("kras23_result");
* }
*
* if (comprehensiveColonCancerProfileResult.KRASExon4MutationIsOrdered == true)
* {
* base.ReplaceText("kras4_result", comprehensiveColonCancerProfileResult.KRASExon4MutationTestOrder.Result);
* base.ReplaceText("kras4_report_no", comprehensiveColonCancerProfileResult.KRASExon4MutationTestOrder.ReportNo);
* }
* else
* {
* this.DeleteRow("kras4_result");
* }
*
* if (comprehensiveColonCancerProfileResult.NRASMutationAnalysisIsOrdered == true)
* {
* base.ReplaceText("nras_result", comprehensiveColonCancerProfileResult.NRASMutationAnalysisTestOrder.Result);
* base.ReplaceText("nras_report_no", comprehensiveColonCancerProfileResult.NRASMutationAnalysisTestOrder.ReportNo);
* }
* else
* {
* this.DeleteRow("nras_result");
* }
*/
base.ReplaceText("pathologist_signature", comprehensiveColonCancerProfile.Signature);
this.SaveReport();
}
public override void ToXml(XElement document)
{
ComprehensiveColonCancerProfile comprehensiveColonCancerProfile = (ComprehensiveColonCancerProfile)this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_ReportNo);
ComprehensiveColonCancerProfileResult comprehensiveColonCancerProfileResult = new ComprehensiveColonCancerProfileResult(this.m_AccessionOrder, comprehensiveColonCancerProfile);
this.AddHeader(document, comprehensiveColonCancerProfile, "Comprehensive Colon Cancer Profile");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Interpretation:", document, "F");
this.HandleLongString(comprehensiveColonCancerProfile.Interpretation, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Pathologist: " + comprehensiveColonCancerProfile.Signature, document, "F");
if (comprehensiveColonCancerProfile.FinalTime.HasValue == true)
{
this.AddNextObxElement("E-signed " + comprehensiveColonCancerProfile.FinalTime.Value.ToString("MM/dd/yyyy HH:mm"), document, "F");
}
this.AddNextObxElement("", document, "F");
this.AddAmendments(document);
string specimenDescription = comprehensiveColonCancerProfileResult.SpecimenOrder.GetSpecimenDescriptionString();
this.HandleLongString("Specimen:", document, "F");
this.HandleLongString(specimenDescription, document, "F");
this.AddNextObxElement("", document, "F");
this.HandleLongString("Diagnosis:", document, "F");
this.HandleLongString(comprehensiveColonCancerProfileResult.SurgicalSpecimen.Diagnosis, document, "F");
this.AddNextObxElement("", document, "F");
this.HandleLongString("AJCC Pathologic Staging:", document, "F");
this.HandleLongString(comprehensiveColonCancerProfileResult.PanelSetOrderSurgical.AJCCStage, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Reference Report: " + comprehensiveColonCancerProfileResult.PanelSetOrderSurgical.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Mismatch Repair Protein Expression by Immunohistochemistry: ", document, "F");
this.AddNextObxElement("MLH1: " + comprehensiveColonCancerProfileResult.PanelSetOrderLynchSyndromeIHC.MLH1Result, document, "F");
this.AddNextObxElement("MSH2: " + comprehensiveColonCancerProfileResult.PanelSetOrderLynchSyndromeIHC.MSH2Result, document, "F");
this.AddNextObxElement("MSH6: " + comprehensiveColonCancerProfileResult.PanelSetOrderLynchSyndromeIHC.MSH6Result, document, "F");
this.AddNextObxElement("PMS2: " + comprehensiveColonCancerProfileResult.PanelSetOrderLynchSyndromeIHC.PMS2Result, document, "F");
this.AddNextObxElement("Reference Report: " + comprehensiveColonCancerProfileResult.PanelSetOrderLynchSyndromeIHC.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
if (comprehensiveColonCancerProfileResult.BRAFV600EKIsOrdered == true ||
comprehensiveColonCancerProfileResult.KRASStandardIsOrderd == true ||
comprehensiveColonCancerProfileResult.MLHIsOrdered == true)
{
this.AddNextObxElement("Molecular Analysis", document, "F");
this.AddNextObxElement("", document, "F");
}
if (comprehensiveColonCancerProfileResult.PanelSetOrderMLH1MethylationAnalysis != null)
{
this.AddNextObxElement("MLH1 Promoter Methylation Analysis: " + comprehensiveColonCancerProfileResult.PanelSetOrderMLH1MethylationAnalysis.ReportNo, document, "F");
this.AddNextObxElement("Result: " + comprehensiveColonCancerProfileResult.PanelSetOrderMLH1MethylationAnalysis.Result, document, "F");
this.AddNextObxElement("", document, "F");
}
if (comprehensiveColonCancerProfileResult.RASRAFIsOrdered == true)
{
this.AddNextObxElement("KRAS Mutation Analysis: " + comprehensiveColonCancerProfileResult.RASRAFTestOrder.ReportNo, document, "F");
this.AddNextObxElement("Result: " + comprehensiveColonCancerProfileResult.RASRAFTestOrder.KRASResult, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("BRAF V600E/K Mutation Analysis: " + comprehensiveColonCancerProfileResult.RASRAFTestOrder.ReportNo, document, "F");
this.AddNextObxElement("Result: " + comprehensiveColonCancerProfileResult.RASRAFTestOrder.BRAFResult, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("NRAS Mutation Analysis: " + comprehensiveColonCancerProfileResult.RASRAFTestOrder.ReportNo, document, "F");
this.AddNextObxElement("Result: " + comprehensiveColonCancerProfileResult.RASRAFTestOrder.NRASResult, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("HRAS Mutation Analysis: " + comprehensiveColonCancerProfileResult.RASRAFTestOrder.ReportNo, document, "F");
this.AddNextObxElement("Result: " + comprehensiveColonCancerProfileResult.RASRAFTestOrder.HRASResult, document, "F");
this.AddNextObxElement("", document, "F");
}
}
public ComprehensiveColonCancerProfileResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
ComprehensiveColonCancerProfile comprehensiveColonCancerProfile)
{
this.m_SpecimenOrder = accessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(comprehensiveColonCancerProfile.OrderedOnId);
this.m_PanelSetOrderSurgical = (YellowstonePathology.Business.Test.Surgical.SurgicalTestOrder)accessionOrder.PanelSetOrderCollection.GetSurgical();
this.m_SurgicalSpecimen = this.m_PanelSetOrderSurgical.SurgicalSpecimenCollection.GetBySpecimenOrderId(this.m_SpecimenOrder.SpecimenOrderId);
bool restrictToOrderedOn = !comprehensiveColonCancerProfile.IncludeTestsPerformedOnOtherBlocks;
YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_LSEIHCIsOrdered = true;
this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
this.m_IHCResult = YellowstonePathology.Business.Test.LynchSyndrome.IHCResult.CreateResultFromResultCode(this.m_PanelSetOrderLynchSyndromeIHC.ResultCode);
}
else
{
YellowstonePathology.Business.Domain.PatientHistory patientHistory = YellowstonePathology.Business.Gateway.AccessionOrderGateway.GetPatientHistory(accessionOrder.PatientId);
if (patientHistory.PanelSetIdExists(102) == true)
{
YellowstonePathology.Business.Domain.PatientHistoryResult patientHistoryResult = patientHistory.GetByPanelSetId(102);
YellowstonePathology.Business.Test.AccessionOrder lseIHCAccessionOrder = Business.Persistence.DocumentGateway.Instance.GetAccessionOrderByMasterAccessionNo(patientHistoryResult.MasterAccessionNo);
this.m_LSEIHCIsOrdered = true;
if (this.m_PanelSetOrderSurgical.MasterAccessionNo == patientHistoryResult.MasterAccessionNo)
{
this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)lseIHCAccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
else
{
this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)lseIHCAccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(102);
}
this.m_IHCResult = YellowstonePathology.Business.Test.LynchSyndrome.IHCResult.CreateResultFromResultCode(this.m_PanelSetOrderLynchSyndromeIHC.ResultCode);
}
}
YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_MLHIsOrdered = true;
this.m_PanelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_BRAFV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_BRAFV600EKIsOrdered = true;
this.m_BRAFV600EKTestOrder = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_KRASStandardTest = new YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_KRASStandardIsOrdered = true;
this.m_KRASStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_KRASExon23MutationTest = new KRASExon23Mutation.KRASExon23MutationTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_KRASExon23MutationIsOrdered = true;
this.m_KRASExon23MutationTestOrder = (KRASExon23Mutation.KRASExon23MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_KRASExon4MutationTest = new KRASExon4Mutation.KRASExon4MutationTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_KRASExon4MutationIsOrdered = true;
this.m_KRASExon4MutationTestOrder = (KRASExon4Mutation.KRASExon4MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_NRASMutationAnalysisTest = new NRASMutationAnalysis.NRASMutationAnalysisTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_NRASMutationAnalysisIsOrdered = true;
this.m_NRASMutationAnalysisTestOrder = (NRASMutationAnalysis.NRASMutationAnalysisTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_RASRAFPanelTest = new RASRAFPanel.RASRAFPanelTest();
if (accessionOrder.PanelSetOrderCollection.Exists(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
{
this.m_RASRAFIsOrdered = true;
this.m_RASRAFPanelTestOrder = (RASRAFPanel.RASRAFPanelTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
}
this.m_SurgicalSpecimenCollection = new YellowstonePathology.Business.Test.Surgical.SurgicalSpecimenCollection();
foreach (YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder in accessionOrder.SpecimenOrderCollection)
{
YellowstonePathology.Business.Test.Surgical.SurgicalSpecimen surgicalSpecimen = this.m_PanelSetOrderSurgical.SurgicalSpecimenCollection.GetBySpecimenOrderId(specimenOrder.SpecimenOrderId);
if (surgicalSpecimen != null)
{
this.m_SurgicalSpecimenCollection.Add(surgicalSpecimen);
}
}
this.m_PanelSetOrderLynchSyndromeIHCCollection = new Collection <LynchSyndrome.PanelSetOrderLynchSyndromeIHC>();
this.m_MolecularTestOrderCollection = new PanelSetOrderCollection();
foreach (YellowstonePathology.Business.Test.PanelSetOrder panelSetOrder in accessionOrder.PanelSetOrderCollection)
{
if (panelSetOrder is YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)
{
this.m_PanelSetOrderLynchSyndromeIHCCollection.Add((YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)panelSetOrder);
}
else
{
if (panelSetOrder is LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis ||
panelSetOrder is KRASStandard.KRASStandardTestOrder ||
panelSetOrder is KRASExon23Mutation.KRASExon23MutationTestOrder ||
panelSetOrder is KRASExon4Mutation.KRASExon4MutationTestOrder ||
panelSetOrder is BRAFV600EK.BRAFV600EKTestOrder ||
panelSetOrder is NRASMutationAnalysis.NRASMutationAnalysisTestOrder ||
panelSetOrder is RASRAFPanel.RASRAFPanelTestOrder)
{
this.m_MolecularTestOrderCollection.Add(panelSetOrder);
}
}
}
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == false)
{
YellowstonePathology.Business.Domain.PatientHistory patientHistory = YellowstonePathology.Business.Gateway.AccessionOrderGateway.GetPatientHistory(accessionOrder.PatientId);
if (patientHistory.PanelSetIdExists(102) == true)
{
YellowstonePathology.Business.Domain.PatientHistoryResult patientHistoryResult = patientHistory.GetByPanelSetId(102);
YellowstonePathology.Business.Test.AccessionOrder lseIHCAccessionOrder = Business.Persistence.DocumentGateway.Instance.GetAccessionOrderByMasterAccessionNo(patientHistoryResult.MasterAccessionNo);
this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)lseIHCAccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(102);
this.m_PanelSetOrderLynchSyndromeIHCCollection.Add(m_PanelSetOrderLynchSyndromeIHC);
}
}
}
public override void ToXml(XElement document)
{
ComprehensiveColonCancerProfile comprehensiveColonCancerProfile = (ComprehensiveColonCancerProfile)this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_ReportNo);
ComprehensiveColonCancerProfileResult comprehensiveColonCancerProfileResult = new ComprehensiveColonCancerProfileResult(this.m_AccessionOrder, comprehensiveColonCancerProfile);
this.AddHeader(document, comprehensiveColonCancerProfile, "Comprehensive Colon Cancer Profile");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Interpretation:", document, "F");
this.HandleLongString(comprehensiveColonCancerProfile.Interpretation, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Pathologist: " + comprehensiveColonCancerProfile.Signature, document, "F");
if (comprehensiveColonCancerProfile.FinalTime.HasValue == true)
{
this.AddNextObxElement("E-signed " + comprehensiveColonCancerProfile.FinalTime.Value.ToString("MM/dd/yyyy HH:mm"), document, "F");
}
this.AddNextObxElement("", document, "F");
this.AddAmendments(document);
foreach (YellowstonePathology.Business.Test.Surgical.SurgicalSpecimen surgicalSpecimen in comprehensiveColonCancerProfileResult.SurgicalSpecimenCollection)
{
YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrder(surgicalSpecimen.SpecimenOrderId);
StringBuilder specimenDescription = new StringBuilder();
specimenDescription.Append(specimenOrder.Description + ": ");
foreach (YellowstonePathology.Business.Test.AliquotOrder aliquotOrder in specimenOrder.AliquotOrderCollection)
{
specimenDescription.Append(aliquotOrder.Label + ", ");
}
specimenDescription.Remove(specimenDescription.Length - 2, 2);
this.AddNextObxElement("Specimen:", document, "F");
this.HandleLongString(specimenDescription.ToString(), document, "F");
this.AddNextObxElement("", document, "F");
this.HandleLongString("Diagnosis:", document, "F");
this.HandleLongString(surgicalSpecimen.Diagnosis, document, "F");
this.AddNextObxElement("", document, "F");
}
this.HandleLongString("AJCC Pathologic Staging:", document, "F");
this.HandleLongString(comprehensiveColonCancerProfileResult.PanelSetOrderSurgical.AJCCStage, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Reference Report: " + comprehensiveColonCancerProfileResult.PanelSetOrderSurgical.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Mismatch Repair Protein Expression by Immunohistochemistry: ", document, "F");
if (comprehensiveColonCancerProfileResult.PanelSetOrderLynchSyndromeIHCCollection.Count > 0)
{
foreach (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC testOrder in comprehensiveColonCancerProfileResult.PanelSetOrderLynchSyndromeIHCCollection)
{
this.AddNextObxElement("MLH1: " + testOrder.MLH1Result, document, "F");
this.AddNextObxElement("PMS2: " + testOrder.PMS2Result, document, "F");
this.AddNextObxElement("MSH2: " + testOrder.MSH2Result, document, "F");
this.AddNextObxElement("MSH6: " + testOrder.MSH6Result, document, "F");
this.AddNextObxElement("Reference Report: " + testOrder.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
}
}
else
{
this.AddNextObxElement("MLH1: " + "Not Included", document, "F");
this.AddNextObxElement("PMS2: " + "Not Included", document, "F");
this.AddNextObxElement("MSH2: " + "Not Included", document, "F");
this.AddNextObxElement("MSH6: " + "Not Included", document, "F");
this.AddNextObxElement("", document, "F");
}
this.AddNextObxElement("Molecular Analysis", document, "F");
if (comprehensiveColonCancerProfileResult.MolecularTestOrderCollection.Count > 0)
{
foreach (YellowstonePathology.Business.Test.PanelSetOrder testOrder in comprehensiveColonCancerProfileResult.MolecularTestOrderCollection)
{
YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimen = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(testOrder.OrderedOnId);
YellowstonePathology.Business.Test.AliquotOrder aliquot = specimen.AliquotOrderCollection.GetByAliquotOrderId(testOrder.OrderedOnId);
if (testOrder is LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)
{
this.AddNextObxElement("MLH1 Promoter Methylation Analysis: " + ((LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)testOrder).Result, document, "F");
this.AddNextObxElement("Specimen: " + aliquot.Label, document, "F");
this.AddNextObxElement("Reference Report: " + testOrder.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
}
else if (testOrder is KRASStandard.KRASStandardTestOrder)
{
this.AddNextObxElement("KRAS Mutation Analysis: " + ((KRASStandard.KRASStandardTestOrder)testOrder).Result, document, "F");
this.AddNextObxElement("Specimen: " + aliquot.Label, document, "F");
this.AddNextObxElement("Reference Report: " + testOrder.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
}
else if (testOrder is KRASExon23Mutation.KRASExon23MutationTestOrder)
{
this.AddNextObxElement("KRAS Exon 23 Mutation Analysis: " + ((KRASExon23Mutation.KRASExon23MutationTestOrder)testOrder).Result, document, "F");
this.AddNextObxElement("Specimen: " + aliquot.Label, document, "F");
this.AddNextObxElement("Reference Report: " + testOrder.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
}
else if (testOrder is KRASExon4Mutation.KRASExon4MutationTestOrder)
{
this.AddNextObxElement("KRAS Exon 4 Mutation Analysis: " + ((KRASExon4Mutation.KRASExon4MutationTestOrder)testOrder).Result, document, "F");
this.AddNextObxElement("Specimen: " + aliquot.Label, document, "F");
this.AddNextObxElement("Reference Report: " + testOrder.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
}
else if (testOrder is BRAFV600EK.BRAFV600EKTestOrder)
{
this.AddNextObxElement("BRAF V600E Mutation Analysis: " + ((BRAFV600EK.BRAFV600EKTestOrder)testOrder).Result, document, "F");
this.AddNextObxElement("Specimen: " + aliquot.Label, document, "F");
this.AddNextObxElement("Reference Report: " + testOrder.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
}
else if (testOrder is NRASMutationAnalysis.NRASMutationAnalysisTestOrder)
{
this.AddNextObxElement("NRAS Mutation Analysis: " + ((NRASMutationAnalysis.NRASMutationAnalysisTestOrder)testOrder).Result, document, "F");
this.AddNextObxElement("Specimen: " + aliquot.Label, document, "F");
this.AddNextObxElement("Reference Report: " + testOrder.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
}
else if (testOrder is RASRAFPanel.RASRAFPanelTestOrder)
{
this.AddNextObxElement("KRAS Mutation Analysis: " + ((RASRAFPanel.RASRAFPanelTestOrder)testOrder).KRASResult, document, "F");
this.AddNextObxElement("Specimen: " + aliquot.Label, document, "F");
this.AddNextObxElement("Reference Report: " + testOrder.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("BRAF V600E/K Mutation Analysis: " + ((RASRAFPanel.RASRAFPanelTestOrder)testOrder).BRAFResult, document, "F");
this.AddNextObxElement("Specimen: " + aliquot.Label, document, "F");
this.AddNextObxElement("Reference Report: " + testOrder.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("NRAS Mutation Analysis: " + ((RASRAFPanel.RASRAFPanelTestOrder)testOrder).NRASResult, document, "F");
this.AddNextObxElement("Specimen: " + aliquot.Label, document, "F");
this.AddNextObxElement("Reference Report: " + testOrder.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("HRAS Mutation Analysis: " + ((RASRAFPanel.RASRAFPanelTestOrder)testOrder).HRASResult, document, "F");
this.AddNextObxElement("Specimen: " + aliquot.Label, document, "F");
this.AddNextObxElement("Reference Report: " + testOrder.ReportNo, document, "F");
this.AddNextObxElement("", document, "F");
}
}
}
else
{
this.AddNextObxElement("None Performed", document, "F");
this.AddNextObxElement("", document, "F");
}
}