public void compute_proteoform_statistics(List <ExperimentalProteoform> satisfactoryProteoforms, decimal bkgdAverageIntensity, decimal bkgdStDev, Dictionary <string, List <string> > conditionsBioReps, string numerator_condition, string denominator_condition, string induced_condition, decimal sKnot_minFoldChange, bool define_histogram)
{
foreach (ExperimentalProteoform eP in satisfactoryProteoforms)
{
eP.quant.TusherValues2.impute_biorep_intensities(eP.biorepTechrepIntensityList, conditionsBioReps, numerator_condition, denominator_condition, induced_condition, bkgdAverageIntensity, bkgdStDev, sKnot_minFoldChange, Sweet.lollipop.useRandomSeed_quant, Sweet.lollipop.seeded);
eP.quant.determine_statistics();
}
if (define_histogram)
{
QuantitativeDistributions.defineSelectObservedWithImputedIntensityDistribution(satisfactoryProteoforms.SelectMany(pf => pf.quant.TusherValues2.allIntensities.Values), QuantitativeDistributions.logSelectIntensityWithImputationHistogram);
}
normalize_protoeform_intensities(satisfactoryProteoforms);
foreach (ExperimentalProteoform eP in satisfactoryProteoforms)
{
eP.quant.TusherValues2.determine_proteoform_statistics(induced_condition, sKnot_minFoldChange);
}
}
public Log2FoldChangeAnalysis()
{
this.QuantitativeDistributions = new QuantitativeDistributions(this);
}
public TusherAnalysis()
{
this.QuantitativeDistributions = new QuantitativeDistributions(this);
}