/// <summary>
/// calculates the hash code for this object
/// </summary>
// ReSharper disable once FunctionComplexityOverflow
private int CalculateHashCode()
{
var hashCode = Start.GetHashCode();
if (Chromosome != null)
{
hashCode ^= Chromosome.GetHashCode();
}
if (ID != null)
{
hashCode ^= ID.GetHashCode();
}
if (AlleleOrigins != null)
{
hashCode ^= AlleleOrigins.GetHashCode();
}
if (AltAllele != null)
{
hashCode ^= AltAllele.GetHashCode();
}
if (MedGenIDs != null)
{
hashCode ^= MedGenIDs.GetHashCode();
}
if (OmimIDs != null)
{
hashCode ^= OmimIDs.GetHashCode();
}
if (OrphanetIDs != null)
{
hashCode ^= OrphanetIDs.GetHashCode();
}
if (Phenotypes != null)
{
hashCode ^= Phenotypes.GetHashCode();
}
if (ReferenceAllele != null)
{
hashCode ^= ReferenceAllele.GetHashCode();
}
if (Significance != null)
{
hashCode ^= Significance.GetHashCode();
}
return(hashCode);
}
private List <string[]> GetValues()
{
var values = new List <string[]>
{
//the exact order of adding values has to be preserved. the order is dictated by the json schema
new[] { Id },
new[] { VariationId },
new[] { ClinVarCommon.ReviewStatusStrings[ReviewStatus] },
AlleleOrigins?.ToArray(),
new[] { ClinVarCommon.NormalizeAllele(RefAllele) },
new[] { ClinVarCommon.NormalizeAllele(AltAllele) },
Phenotypes?.ToArray(),
MedGenIds?.ToArray(),
OmimIds?.ToArray(),
OrphanetIds?.ToArray(),
Significances,
new[] { new DateTime(LastUpdatedDate).ToString("yyyy-MM-dd") },
PubmedIds?.OrderBy(x => x).Select(x => x.ToString()).ToArray()
};
return(values);
}
public Boolean cargarArchivo()
{
logger.EscribirLog("Cargamos los Fenotipos de PharmaGKB", Logger.Tipo.Informativo, false);
logger.EscribirLog("Chequeamos si existe el Archivo " + filePath, Logger.Tipo.Informativo, false);
if (!File.Exists(filePath))
{
logger.EscribirLog("No existe el Archivo " + filePath, Logger.Tipo.Informativo, false);
return(false);
}
foreach (string Phenotypes in File.ReadAllLines(filePath))
{
string[] varsa = Phenotypes.Split('\t');
if (varsa[0] != "PharmGKB Accession Id")
{
Phenotype phenotype = new Phenotype();
phenotype.PharmGKBAccessionId = varsa[0];
phenotype.Name = varsa[1];
string[] AlternateNames = varsa[2].Split(',');
foreach (String s in AlternateNames)
{
if (s.Contains("\""))
{
phenotype.AlternateNames.Add(s.Split('"')[1]);
}
else
{
phenotype.AlternateNames.Add(s);
}
}
string[] CrossReferences = varsa[3].Split(',');
foreach (String s in CrossReferences)
{
if (s.Contains("\""))
{
phenotype.CrossReferences.Add(s.Split('"')[1]);
}
else
{
phenotype.CrossReferences.Add(s);
}
}
string[] ExtenralVocabulary = varsa[4].Split(',');
foreach (String s in ExtenralVocabulary)
{
if (s.Contains("\""))
{
phenotype.ExtenralVocabulary.Add(s.Split('"')[1]);
}
else
{
phenotype.ExtenralVocabulary.Add(s);
}
}
LPhenotypes.Add(phenotype);
}
}
logger.EscribirLog("Cargamos " + LPhenotypes.Count + " Fenotipos", Logger.Tipo.Informativo, true);
return(true);
}
