protected override void Context()
{
base.Context();
_parameter = A.Fake <IParameterDTO>();
_expressionParameterDTO = new ExpressionParameterDTO {
Parameter = _parameter, GroupName = CoreConstants.Groups.VASCULAR_SYSTEM
};
}
protected override void Context()
{
_view = A.Fake <IExpressionParametersView <ExpressionParameterDTO> >();
_editParameterTask = A.Fake <IEditParameterPresenterTask>();
sut = new ExpressionParametersPresenter(_view, _editParameterTask);
_initialConcentration = createParameter(CoreConstants.Parameters.INITIAL_CONCENTRATION);
_relativeExpression = createParameter(CoreConstants.Parameters.REL_EXP);
_relativeExpression2 = createParameter(CoreConstants.Parameters.REL_EXP);
_fraction_exp_bc = createParameter(CoreConstants.Parameters.FRACTION_EXPRESSED_BLOOD_CELLS);
}
//Internal to allow for testing
internal bool IsParameterVisible(ExpressionParameterDTO expressionParameterDTO)
{
var parameter = expressionParameterDTO.Parameter;
//global surrogate parameters depending on settings
if (string.Equals(expressionParameterDTO.GroupName, CoreConstants.Groups.VASCULAR_SYSTEM))
{
switch (parameter.Name)
{
case REL_EXP_BLOOD_CELLS:
return(_protein.InBloodCells);
case FRACTION_EXPRESSED_BLOOD_CELLS:
case FRACTION_EXPRESSED_BLOOD_CELLS_MEMBRANE:
return(_protein.IsBloodCellsMembrane && _protein.IsBloodCellsIntracellular);
case REL_EXP_VASCULAR_ENDOTHELIUM:
return(_protein.InVascularEndothelium);
case FRACTION_EXPRESSED_VASC_ENDO_ENDOSOME:
return(_protein.IsVascEndosome && (_protein.IsVascMembraneTissueSide || _protein.IsVascMembranePlasmaSide));
case FRACTION_EXPRESSED_VASC_ENDO_TISSUE_SIDE:
return(_protein.IsVascMembraneTissueSide && (_protein.IsVascEndosome || _protein.IsVascMembranePlasmaSide));
case FRACTION_EXPRESSED_VASC_ENDO_PLASMA_SIDE:
return(_protein.IsVascMembranePlasmaSide && (_protein.IsVascEndosome || _protein.IsVascMembraneTissueSide));
}
}
//tissue location. Rel exp visible if we are expressing it
switch (parameter.Name)
{
case REL_EXP:
return(_protein.InTissue);
case FRACTION_EXPRESSED_INTRACELLULAR:
case FRACTION_EXPRESSED_INTERSTITIAL:
return(_protein.IsIntracellular && _protein.IsInterstitial);
}
return(true);
}
protected override void Context()
{
_view = A.Fake <IIndividualProteinExpressionsView>();
_individualProteinMapper = A.Fake <IIndividualProteinToIndividualProteinDTOMapper>();
_moleculesPropertiesPresenter = A.Fake <IIndividualMoleculePropertiesPresenter <Individual> >();
_expressionLocalizationPresenter = A.Fake <IExpressionLocalizationPresenter <Individual> >();
_expressionParametersPresenter = A.Fake <IExpressionParametersPresenter>();
sut = new IndividualEnzymeExpressionsPresenter <Individual>(
_view, _individualProteinMapper,
_moleculesPropertiesPresenter,
_expressionLocalizationPresenter,
_expressionParametersPresenter);
_individual = new Individual();
sut.SimulationSubject = _individual;
_enzyme = new IndividualEnzyme().WithName("CYP3A4");
_enzymeDTO = new IndividualProteinDTO(_enzyme);
_initialConcentration = createParameter(INITIAL_CONCENTRATION);
_relativeExpression = createParameter(REL_EXP);
_relativeExpression2 = createParameter(REL_EXP);
_fraction_exp_bc = createParameter(FRACTION_EXPRESSED_BLOOD_CELLS);
_enzymeDTO.AddExpressionParameter(_initialConcentration);
_enzymeDTO.AddExpressionParameter(_relativeExpression);
_enzymeDTO.AddExpressionParameter(_fraction_exp_bc);
A.CallTo(() => _individualProteinMapper.MapFrom(_enzyme, _individual)).Returns(_enzymeDTO);
A.CallTo(() => _expressionParametersPresenter.Edit(A <IReadOnlyList <ExpressionParameterDTO> > ._))
.Invokes(x => _allParameters = x.GetArgument <IReadOnlyList <ExpressionParameterDTO> >(0).ToList());
sut.ActivateMolecule(_enzyme);
}
