public void GetCdnaPositionOffset_Exon_Reverse()
{
var transcript = HgvsCodingNomenclatureTests.GetReverseTranscript();
var po = HgvsUtilities.GetCdnaPositionOffset(transcript, 137721, 2, true);
Assert.NotNull(po);
Assert.True(po.HasStopCodonNotation);
Assert.Equal(0, po.Offset);
Assert.Equal(1659, po.Position);
Assert.Equal("*809", po.Value);
}
public void GetCdnaPositionOffset_Exon_Forward()
{
var transcript = HgvsCodingNomenclatureTests.GetForwardTranscript();
var po = HgvsUtilities.GetCdnaPositionOffset(transcript, 1262627, 4, true);
Assert.NotNull(po);
Assert.False(po.HasStopCodonNotation);
Assert.Equal(0, po.Offset);
Assert.Equal(540, po.Position);
Assert.Equal("129", po.Value);
}
public void GetCdnaPositionOffset_Intron_LeqR_Forward()
{
var transcript = HgvsCodingNomenclatureTests.GetForwardTranscript();
var po = HgvsUtilities.GetCdnaPositionOffset(transcript, 1261349, 1, true);
Assert.NotNull(po);
Assert.False(po.HasStopCodonNotation);
Assert.Equal(867, po.Offset);
Assert.Equal(336, po.Position);
Assert.Equal("-76+867", po.Value);
}
public void GetCdnaPositionOffset_Intron_LltR_Reverse()
{
var transcript = HgvsCodingNomenclatureTests.GetReverseTranscript();
var po = HgvsUtilities.GetCdnaPositionOffset(transcript, 136000, 1, true);
Assert.NotNull(po);
Assert.True(po.HasStopCodonNotation);
Assert.Equal(-198, po.Offset);
Assert.Equal(1760, po.Position);
Assert.Equal("*910-198", po.Value);
}
public void GetCdnaPositionOffset_Intron_RltL_Reverse()
{
var transcript = HgvsCodingNomenclatureTests.GetReverseTranscript();
var po = HgvsUtilities.GetCdnaPositionOffset(transcript, 137619, 1, true);
Assert.NotNull(po);
Assert.True(po.HasStopCodonNotation);
Assert.Equal(2, po.Offset);
Assert.Equal(1759, po.Position);
Assert.Equal("*909+2", po.Value);
}
public void GetCdnaPositionOffset_Intron_RltL_Forward()
{
var transcript = HgvsCodingNomenclatureTests.GetForwardTranscript();
var po = HgvsUtilities.GetCdnaPositionOffset(transcript, 1262210, 1);
Assert.NotNull(po);
Assert.False(po.HasStopCodonNotation);
Assert.Equal(-6, po.Offset);
Assert.Equal(337, po.Position);
Assert.Equal("-75-6", po.Value);
}
