public List <parentMetabolite> ListOfMetabolites; //metabolite object, level (apriori normalized or non-normalized)
public sampleForTissueAndCharge(List <string> _metabolitebVals, List <msMetabolite> _lom)
{
Id = _metabolitebVals.ElementAt(publicVariables.indexToStartFrom - 3);
Tissue = _metabolitebVals.ElementAt(publicVariables.indexToStartFrom - 2);
Charge = _metabolitebVals.ElementAt(publicVariables.indexToStartFrom - 1);
Phenotype = (clinicalData.List_clinicalData.Any(x => x.Id == Id)) ? clinicalData.List_clinicalData.First(x => x.Id == Id).Phenotype : "U";
ListOfNumClinicalData = new List <sampleClinicalData>();
// add sample weight values
if (clinicalData.List_clinicalData.First(x => x.Id == Id).SampleWeight_covariates.Count != 0)
{
ListOfNumClinicalData.Add(new sampleClinicalData()
{
name = "sampleweight",
n_value = ((publicVariables.prefixValues.mixed == publicVariables.prefix || publicVariables.prefixValues.gcms == publicVariables.prefix)
? clinicalData.List_clinicalData.First(x => x.Id == Id).SampleWeight_covariates.Where(x => x.tissue.ToLower() == Tissue.ToLower()).Average(x => x.weight.Imputed)
: clinicalData.List_clinicalData.First(x => x.Id == Id).SampleWeight_covariates
.First(x => x.tissue.ToLower() == Tissue.ToLower() && x.charge.ToLower() == Charge.ToLower()).weight.Imputed),
typeOf = sampleClinicalData.type.numeric
});
}
// add numerical clinical data
foreach (KeyValuePair <string, imputedValues> kvp_nv in clinicalData.List_clinicalData.First(x => x.Id == Id).Numerical_covariates)
{
ListOfNumClinicalData.Add(new sampleClinicalData()
{
name = kvp_nv.Key,
n_value = kvp_nv.Value.Imputed,
typeOf = sampleClinicalData.type.numeric
});
}
// add categorical clinical data
foreach (KeyValuePair <string, string> kvp_cv in clinicalData.List_clinicalData.First(x => x.Id == Id).Categorical_covariates)
{
ListOfNumClinicalData.Add(new sampleClinicalData()
{
name = kvp_cv.Key,
c_value = kvp_cv.Value,
typeOf = sampleClinicalData.type.categorical
});
}
// add metabolite levels values
ListOfMetabolites = new List <parentMetabolite>();
foreach (msMetabolite _m in _lom)
{
if (string.IsNullOrEmpty(_metabolitebVals.ElementAt(_m.In_Index)) || string.IsNullOrWhiteSpace(_metabolitebVals.ElementAt(_m.In_Index)))
{
ListOfMetabolites.Add(new parentMetabolite()
{
mtbltDetails = _m,
mtbltVals = new imputedValues()
{
Imputed = -1,
Non_imputed = -1
}
});
}
else
{
ListOfMetabolites.Add(new parentMetabolite()
{
mtbltDetails = _m,
mtbltVals = new imputedValues()
{
Imputed = Convert.ToDouble(_metabolitebVals.ElementAt(_m.In_Index)),
Non_imputed = Convert.ToDouble(_metabolitebVals.ElementAt(_m.In_Index))
}
});
}
}
}