private void ReadHeader()
{
_stream.Seek(-sizeof(long), SeekOrigin.End);
_locationHeader = PrimitiveArrays.ReadOneValue <long>(_stream);
_stream.Seek(_locationHeader, SeekOrigin.Begin);
int version = PrimitiveArrays.ReadOneValue <int>(_stream);
if (version > CURRENT_VERSION || version < MIN_READABLE_VERSION)
{
throw new InvalidDataException(string.Format(Resources.Serializer_ReadHeader_Unsupported_file_version__0_, version));
}
_locationEntries = PrimitiveArrays.ReadOneValue <long>(_stream);
_library.PanoramaServer = ReadString(_stream);
_library.LibraryRevision = PrimitiveArrays.ReadOneValue <int>(_stream);
_library.SchemaVersion = ReadString(_stream);
var sampleFileCount = PrimitiveArrays.ReadOneValue <int>(_stream);
var sampleFiles = new List <ChromatogramLibrarySourceInfo>();
for (int i = 0; i < sampleFileCount; i++)
{
sampleFiles.Add(ChromatogramLibrarySourceInfo.Read(_stream));
}
_library._librarySourceFiles = sampleFiles.ToArray();
_locationEntries = PrimitiveArrays.ReadOneValue <long>(_stream);
}
public static ElibSpectrumInfo Read(ValueCache valueCache, Stream stream)
{
byte[] peptideModSeqBytes = new byte[PrimitiveArrays.ReadOneValue <int>(stream)];
stream.Read(peptideModSeqBytes, 0, peptideModSeqBytes.Length);
var peptideModSeq = valueCache.CacheValue(Encoding.UTF8.GetString(peptideModSeqBytes));
int charge = PrimitiveArrays.ReadOneValue <int>(stream);
int bestFileId = PrimitiveArrays.ReadOneValue <int>(stream);
int peakBoundCount = PrimitiveArrays.ReadOneValue <int>(stream);
var peakBounds = new List <KeyValuePair <int, FileData> >();
while (peakBounds.Count < peakBoundCount)
{
var fileId = PrimitiveArrays.ReadOneValue <int>(stream);
var startTime = PrimitiveArrays.ReadOneValue <double>(stream);
var endTime = PrimitiveArrays.ReadOneValue <double>(stream);
var score = PrimitiveArrays.ReadOneValue <double>(stream);
byte bHasApexTime = PrimitiveArrays.ReadOneValue <byte>(stream);
double?apexTime;
if (bHasApexTime == 0)
{
apexTime = null;
}
else
{
apexTime = PrimitiveArrays.ReadOneValue <double>(stream);
}
peakBounds.Add(new KeyValuePair <int, FileData>(fileId, new FileData(apexTime, new ExplicitPeakBounds(startTime, endTime, score))));
}
return(new ElibSpectrumInfo(peptideModSeq, charge, bestFileId, peakBounds));
}
public static LibraryKey Read(ValueCache valueCache, Stream stream)
{
int length = PrimitiveArrays.ReadOneValue <int>(stream);
byte[] buffer = new byte[length];
stream.Read(buffer, 0, length);
var proto = new LibraryKeyProto();
proto.MergeFrom(new CodedInputStream(buffer));
switch (proto.KeyType)
{
case LibraryKeyProto.Types.KeyType.Peptide:
return(new PeptideLibraryKey(proto.ModifiedSequence, proto.Charge).ValueFromCache(valueCache));
case LibraryKeyProto.Types.KeyType.PrecursorMz:
return(new PrecursorLibraryKey(proto));
case LibraryKeyProto.Types.KeyType.SmallMolecule:
return(new MoleculeLibraryKey(valueCache, proto));
case LibraryKeyProto.Types.KeyType.Crosslink:
return(new CrosslinkLibraryKey(proto));
}
return(null);
}
private static string ReadString(Stream stream)
{
int byteLength = PrimitiveArrays.ReadOneValue <int>(stream);
var bytes = new byte[byteLength];
stream.Read(bytes, 0, bytes.Length);
return(Encoding.UTF8.GetString(bytes));
}
public static ChromatogramLibraryIrt Read(Stream stream)
{
var seq = Target.FromSerializableString(ReadString(stream));
var timeSource = (TimeSource)PrimitiveArrays.ReadOneValue <int>(stream);
var irt = PrimitiveArrays.ReadOneValue <double>(stream);
return(new ChromatogramLibraryIrt(seq, timeSource, irt));
}
public static ChromatogramLibrarySourceInfo Read(Stream stream)
{
int id = PrimitiveArrays.ReadOneValue <int>(stream);
string filePath = ReadString(stream);
string sampleName = ReadString(stream);
string acquiredTime = ReadString(stream);
string modifiedTime = ReadString(stream);
string instrumentIonizationType = ReadString(stream);
string instrumentAnalyzer = ReadString(stream);
string instrumentDetector = ReadString(stream);
return(new ChromatogramLibrarySourceInfo(id, filePath, sampleName, acquiredTime, modifiedTime, instrumentIonizationType,
instrumentAnalyzer, instrumentDetector));
}
public static ChromLibSpectrumInfo Read(Stream stream)
{
LibKey key = LibKey.Read(stream);
int id = PrimitiveArrays.ReadOneValue <int>(stream);
double peakArea = PrimitiveArrays.ReadOneValue <double>(stream);
var retentionTimesByFileId = IndexedRetentionTimes.Read(stream);
int mzCount = PrimitiveArrays.ReadOneValue <int>(stream);
var mzs = PrimitiveArrays.Read <double>(stream, mzCount);
var areas = PrimitiveArrays.Read <float>(stream, mzCount);
var mzAreas = ImmutableList.ValueOf(Enumerable.Range(0, mzCount)
.Select(index => new SpectrumPeaksInfo.MI
{
Mz = mzs[index],
Intensity = areas[index]
}));
return(new ChromLibSpectrumInfo(key, id, peakArea, retentionTimesByFileId, mzAreas));
}
private void ReadEntries()
{
_stream.Seek(_locationEntries, SeekOrigin.Begin);
int entryCount = PrimitiveArrays.ReadOneValue <int>(_stream);
var entries = new ChromLibSpectrumInfo[entryCount];
for (int i = 0; i < entryCount; i++)
{
entries[i] = ChromLibSpectrumInfo.Read(_stream);
}
_library.SetLibraryEntries(entries);
int irtCount = PrimitiveArrays.ReadOneValue <int>(_stream);
_library._libraryIrts = new ChromatogramLibraryIrt[irtCount];
for (int i = 0; i < irtCount; i++)
{
_library._libraryIrts[i] = ChromatogramLibraryIrt.Read(_stream);
}
}
private bool LoadFromCache(ILoadMonitor loader)
{
if (!loader.StreamManager.IsCached(FilePath, CachePath))
{
return(false);
}
try
{
ValueCache valueCache = new ValueCache();
using (var stream = loader.StreamManager.CreateStream(CachePath, FileMode.Open, true))
{
int version = PrimitiveArrays.ReadOneValue <int>(stream);
if (version != FORMAT_VERSION_CACHE)
{
return(false);
}
int fileCount = PrimitiveArrays.ReadOneValue <int>(stream);
List <String> sourceFiles = new List <string>(fileCount);
while (sourceFiles.Count < fileCount)
{
int byteCount = PrimitiveArrays.ReadOneValue <int>(stream);
byte[] bytes = new byte[byteCount];
stream.Read(bytes, 0, bytes.Length);
sourceFiles.Add(Encoding.UTF8.GetString(bytes));
}
int spectrumInfoCount = PrimitiveArrays.ReadOneValue <int>(stream);
_sourceFiles = ImmutableList.ValueOf(sourceFiles);
List <ElibSpectrumInfo> spectrumInfos = new List <ElibSpectrumInfo>();
while (spectrumInfos.Count < spectrumInfoCount)
{
spectrumInfos.Add(ElibSpectrumInfo.Read(valueCache, stream));
}
SetLibraryEntries(spectrumInfos);
return(true);
}
}
catch (Exception exception)
{
Trace.TraceWarning(@"Exception loading cache: {0}", exception);
return(false);
}
}
private bool Load(ILoadMonitor loader, IProgressStatus status, bool cached)
{
try
{
int loadPercent = 100;
if (!cached)
{
// Building the cache will take 95% of the load time.
loadPercent = 5;
status = status.ChangeMessage(string.Format(Resources.XHunterLibrary_Load_Building_binary_cache_for__0__library, Path.GetFileName(FilePath)));
status = status.ChangePercentComplete(0);
loader.UpdateProgress(status);
if (!CreateCache(loader, status, 100 - loadPercent))
{
return(false);
}
}
status = status.ChangeMessage(string.Format(Resources.XHunterLibrary_Load_Loading__0__library, Path.GetFileName(FilePath)));
loader.UpdateProgress(status);
var valueCache = new ValueCache();
var sm = loader.StreamManager;
using (Stream stream = sm.CreateStream(CachePath, FileMode.Open, true))
{
// Read library header from the end of the cache
int countHeader = (int)LibHeaders.count * sizeof(int);
stream.Seek(-countHeader, SeekOrigin.End);
byte[] libHeader = new byte[countHeader];
ReadComplete(stream, libHeader, countHeader);
int version = GetInt32(libHeader, (int)LibHeaders.format_version);
if (version != FORMAT_VERSION_CACHE)
{
return(false);
}
int countRevisionBytes = GetInt32(libHeader, (int)LibHeaders.revision_byte_count);
int countIdBytes = GetInt32(libHeader, (int)LibHeaders.id_byte_count);
stream.Seek(-countHeader - countRevisionBytes - countIdBytes, SeekOrigin.End);
Revision = ReadString(stream, countRevisionBytes);
Id = ReadString(stream, countIdBytes);
int numSpectra = GetInt32(libHeader, (int)LibHeaders.num_spectra);
var libraryEntries = new XHunterSpectrumInfo[numSpectra];
// Seek to beginning of spectrum headers
long locationHeaders = BitConverter.ToInt64(libHeader,
((int)LibHeaders.location_headers_lo) * sizeof(int));
stream.Seek(locationHeaders, SeekOrigin.Begin);
for (int i = 0; i < numSpectra; i++)
{
int percent = (100 - loadPercent) + (i * loadPercent / numSpectra);
if (status.PercentComplete != percent)
{
// Check for cancellation after each integer change in percent loaded.
if (loader.IsCanceled)
{
loader.UpdateProgress(status.Cancel());
return(false);
}
// If not cancelled, update progress.
loader.UpdateProgress(status = status.ChangePercentComplete(percent));
}
// Read spectrum header
LibKey key = LibKey.Read(valueCache, stream);
long location = PrimitiveArrays.ReadOneValue <long>(stream);
float processedIntensity = PrimitiveArrays.ReadOneValue <float>(stream);
int numPeaks = PrimitiveArrays.ReadOneValue <int>(stream);
float expect = PrimitiveArrays.ReadOneValue <float>(stream);
libraryEntries[i] = new XHunterSpectrumInfo(key, processedIntensity, expect, (short)numPeaks, location);
}
// Checksum = checksum.ChecksumValue;
SetLibraryEntries(libraryEntries);
loader.UpdateProgress(status.Complete());
// Create the stream from which the spectra will be read
CreateStream(loader);
}
return(true);
}
catch (InvalidDataException x)
{
if (!cached)
{
loader.UpdateProgress(status.ChangeErrorException(x));
}
return(false);
}
catch (IOException x)
{
if (!cached)
{
loader.UpdateProgress(status.ChangeErrorException(x));
}
return(false);
}
catch (Exception x)
{
if (!cached)
{
x = new Exception(string.Format(Resources.XHunterLibrary_Load_Failed_loading_library__0__, FilePath), x);
loader.UpdateProgress(status.ChangeErrorException(x));
}
return(false);
}
finally
{
if (ReadStream != null)
{
// Close the read stream to ensure we never leak it.
// This only costs on extra open, the first time the
// active document tries to read.
try { ReadStream.CloseStream(); }
catch (IOException) { }
}
}
}