public SetProteinIntracellularVascularEndoLocationCommand(IndividualProtein protein, IntracellularVascularEndoLocation newVascularEndoLocation, IExecutionContext context)
{
_protein = protein;
_newVascularEndoLocation = newVascularEndoLocation;
BuildingBlockId = context.BuildingBlockIdContaining(protein);
ObjectType = PKSimConstants.ObjectTypes.Protein;
CommandType = PKSimConstants.Command.CommandTypeEdit;
_proteinId = _protein.Id;
context.UpdateBuildinBlockProperties(this, context.BuildingBlockContaining(_protein));
}
public static Localization ConvertToLocalization(TissueLocation tissueLocation, MembraneLocation membraneLocation,
IntracellularVascularEndoLocation vascularEndoLocation)
{
switch (tissueLocation)
{
case TissueLocation.Interstitial:
return(Localization.Interstitial | Localization.BloodCellsIntracellular | Localization.VascMembraneTissueSide);
case TissueLocation.Intracellular:
var vacEndoLocalization = vascularEndoLocation == IntracellularVascularEndoLocation.Endosomal
? Localization.VascEndosome
: Localization.VascMembraneTissueSide;
return(Localization.Intracellular | Localization.BloodCellsIntracellular | vacEndoLocalization);
case TissueLocation.ExtracellularMembrane:
var membLocation = membraneLocation == MembraneLocation.Apical
? Localization.VascMembranePlasmaSide
: Localization.VascMembraneTissueSide;
return(Localization.Interstitial | Localization.BloodCellsMembrane | membLocation);
default:
throw new ArgumentOutOfRangeException(nameof(tissueLocation), tissueLocation, null);
}
}
public void IntracellularLocationVascularEndoChanged(IntracellularVascularEndoLocation vascularEndoLocation)
{
AddCommand(_moleculeExpressionTask.SetIntracellularVascularEndoLocation(_protein, vascularEndoLocation));
}
public ICommand SetIntracellularVascularEndoLocation(IndividualProtein protein, IntracellularVascularEndoLocation vascularEndoLocation)
{
return(new SetProteinIntracellularVascularEndoLocationCommand(protein, vascularEndoLocation, _executionContext).Run(_executionContext));
}
protected override void PerformExecuteWith(IExecutionContext context)
{
_oldVascularEndoLocation = _protein.IntracellularVascularEndoLocation;
_protein.IntracellularVascularEndoLocation = _newVascularEndoLocation;
Description = PKSimConstants.Command.SetProteinMembraneLocationDescription(_oldVascularEndoLocation.ToString(), _newVascularEndoLocation.ToString());
}
