public override void SetISHResults(Business.Specimen.Model.SpecimenOrder specimenOrder)
{
this.m_ResultComment = null;
this.m_ResultDescription = "Ratio = " + this.m_HER2AmplificationByISHTestOrder.Her2Chr17Ratio;
this.m_InterpretiveComment = this.m_InterpretiveComment.Replace("*RATIO*", this.m_HER2AmplificationByISHTestOrder.Her2Chr17Ratio.Value.ToString());
this.m_InterpretiveComment = this.m_InterpretiveComment.Replace("*CELLSCOUNTED*", this.m_HER2AmplificationByISHTestOrder.CellCountToUse.ToString());
if (this.m_HER2AmplificationByISHTestOrder.AverageHer2NeuSignal.HasValue == true)
{
this.m_InterpretiveComment = this.m_InterpretiveComment.Replace("*HER2COPY*", this.m_HER2AmplificationByISHTestOrder.AverageHer2NeuSignal.Value.ToString());
}
Nullable <double> her2Chr17Ratio = this.m_HER2AmplificationByISHTestOrder.AverageHer2Chr17SignalAsDouble;
if (her2Chr17Ratio.HasValue)
{
if (her2Chr17Ratio < 2.0)
{
this.m_Result = HER2AmplificationResultEnum.Negative;
this.m_InterpretiveComment = this.m_InterpretiveComment.Replace("*HER2STATUS*", this.m_Result.ToString());
}
else if (her2Chr17Ratio >= 2.0)
{
this.m_Result = HER2AmplificationResultEnum.Positive;
this.m_InterpretiveComment = this.m_InterpretiveComment.Replace("*HER2STATUS*", this.m_Result.ToString());
}
}
base.SetISHResults(specimenOrder);
}
public void Sync(DataTable dataTable)
{
this.IsLoading = true;
this.RemoveDeleted(dataTable);
DataTableReader dataTableReader = new DataTableReader(dataTable);
while (dataTableReader.Read())
{
string specimenOrderId = dataTableReader["SpecimenOrderId"].ToString();
Business.Specimen.Model.SpecimenOrder specimenOrder = null;
if (this.Exists(specimenOrderId) == true)
{
specimenOrder = this.GetSpecimenOrder(specimenOrderId);
}
else
{
specimenOrder = new Business.Specimen.Model.SpecimenOrder();
this.Add(specimenOrder);
}
YellowstonePathology.Business.Persistence.SqlDataTableReaderPropertyWriter sqlDataTableReaderPropertyWriter = new Persistence.SqlDataTableReaderPropertyWriter(specimenOrder, dataTableReader);
sqlDataTableReaderPropertyWriter.WriteProperties();
}
this.IsLoading = false;
}
public bool CanBuild(Business.Test.AccessionOrder accessionOrder, string testOrderId, string slideOrderId)
{
bool result = false;
Business.Test.PanelOrder panelOrder = accessionOrder.PanelSetOrderCollection.GetPanelOrderByTestOrderId(testOrderId);
Business.User.SystemUser orderedBy = Business.User.SystemUserCollectionInstance.Instance.SystemUserCollection.GetSystemUserById(panelOrder.OrderedById);
Business.Test.AliquotOrder aliquotOrder = accessionOrder.SpecimenOrderCollection.GetAliquotOrderByTestOrderId(testOrderId);
Business.Test.Model.TestOrder testOrder = panelOrder.TestOrderCollection.Get(testOrderId);
Business.Slide.Model.SlideOrder slideOrder = aliquotOrder.SlideOrderCollection.GetSlideOrderByTestOrderId(testOrderId);
Business.Specimen.Model.SpecimenOrder specimenOrder = accessionOrder.SpecimenOrderCollection.GetSpecimenOrderByAliquotOrderId(aliquotOrder.AliquotOrderId);
Business.Stain.Model.Stain stain = Business.Stain.Model.StainCollection.Instance.GetStainByTestId(testOrder.TestId);
if (stain != null)
{
result = true;
if (slideOrder.UseWetProtocol == true)
{
result = false;
if (stain.HasWetProtocol == true || stain.UseWetProtocol == true)
{
result = true;
}
}
}
return(result);
}
public override void SetISHResults(Business.Specimen.Model.SpecimenOrder specimenOrder)
{
this.m_Result = HER2AmplificationResultEnum.Negative;
this.m_InterpretiveComment = InterpretiveComment;
this.m_InterpretiveComment = this.m_InterpretiveComment.Replace("*RATIO*", this.m_HER2AmplificationByISHTestOrder.Her2Chr17Ratio.Value.ToString());
this.m_InterpretiveComment = this.m_InterpretiveComment.Replace("*CELLSCOUNTED*", this.m_HER2AmplificationByISHTestOrder.CellCountToUse.ToString());
this.m_InterpretiveComment = this.m_InterpretiveComment.Replace("*HER2STATUS*", this.m_Result.ToString());
if (this.m_AverageHer2NeuSignal.HasValue == true)
{
this.m_InterpretiveComment = this.m_InterpretiveComment.Replace("*HER2COPY*", this.m_AverageHer2NeuSignal.Value.ToString());
}
base.SetISHResults(specimenOrder);
}
public override void SetSummaryResults(Business.Specimen.Model.SpecimenOrder specimenOrder)
{
this.HandleIHC();
if (this.m_HER2AmplificationRecountTestOrder != null && this.m_HER2AmplificationRecountTestOrder.Accepted == true &&
this.m_PanelSetOrderHer2AmplificationByIHC != null && this.m_PanelSetOrderHer2AmplificationByIHC.Accepted == true)
{
if (this.m_PanelSetOrderHer2AmplificationByIHC.Score.Contains("2+"))
{
this.m_Result = HER2AmplificationByISH.HER2AmplificationResultEnum.Negative;
}
}
base.SetSummaryResults(specimenOrder);
}
public virtual void SetSummaryResults(Business.Specimen.Model.SpecimenOrder specimenOrder)
{
this.m_HER2AnalysisSummaryTestOrder.Result = this.m_Result.ToString();
if (this.m_HER2AnalysisSummaryTestOrder.Result == HER2AmplificationResultEnum.Equivocal.ToString())
{
this.m_InterpretiveComment += Environment.NewLine + Environment.NewLine + "HER2 immunohistochemistry will be performed and " +
"results will be issued in an addendum to the original surgical pathology report.";
}
if (this.m_HER2AnalysisSummaryTestOrder.GeneticHeterogeneity == HER2AmplificationByISHGeneticHeterogeneityCollection.GeneticHeterogeneityPresentInCells)
{
this.m_InterpretiveComment += Environment.NewLine + Environment.NewLine +
"However, this tumor exhibits genetic heterogeneity in HER2 gene amplification in scattered individual cells. The " +
"clinical significance and potential clinical benefit of trastuzumab is uncertain when " +
this.m_HER2AnalysisSummaryTestOrder.Indicator.ToLower() +
" carcinoma demonstrates genetic heterogeneity." + Environment.NewLine + Environment.NewLine;
this.m_ResultComment = "This tumor exhibits genetic heterogeneity in HER2 gene amplification in scattered individual cells. The clinical " +
"significance and potential clinical benefit of trastuzumab is uncertain when " +
this.m_HER2AnalysisSummaryTestOrder.Indicator.ToLower() +
" carcinoma demonstrates genetic heterogeneity";
}
else if (this.m_HER2AnalysisSummaryTestOrder.GeneticHeterogeneity == HER2AmplificationByISHGeneticHeterogeneityCollection.GeneticHeterogeneityPresentInClusters)
{
this.m_InterpretiveComment += Environment.NewLine + Environment.NewLine +
"However, this tumor exhibits genetic heterogeneity in HER2 gene amplification in small cell clusters. The HER2/Chr17 " +
"ratio in the clusters is " +
this.m_HER2AnalysisSummaryTestOrder.Her2Chr17ClusterRatio +
". The clinical significance and potential clinical benefit of trastuzumab is uncertain when " +
this.m_HER2AnalysisSummaryTestOrder.Indicator.ToLower() +
" carcinoma demonstrates genetic heterogeneity." + Environment.NewLine + Environment.NewLine;
this.m_ResultComment = "This tumor exhibits genetic heterogeneity in HER2 gene amplification in small cell clusters. The clinical significance " +
"and potential clinical benefit of trastuzumab is uncertain when " +
this.m_HER2AnalysisSummaryTestOrder.Indicator.ToLower() +
" carcinoma demonstrates genetic heterogeneity.";
}
this.m_HER2AnalysisSummaryTestOrder.ResultComment = this.m_ResultComment;
this.m_HER2AnalysisSummaryTestOrder.InterpretiveComment = this.m_InterpretiveComment.TrimEnd();
this.m_HER2AnalysisSummaryTestOrder.ResultDescription = this.m_ResultDescription;
this.m_HER2AnalysisSummaryTestOrder.CommentLabel = null;
this.m_HER2AnalysisSummaryTestOrder.ReportReference = this.m_ReportReference;
this.m_HER2AnalysisSummaryTestOrder.NoCharge = false;
if (specimenOrder.FixationDuration > 72 || specimenOrder.FixationDuration < 6)
{
specimenOrder.FixationComment = m_FixationOutOfBoundsComment;
}
}
public MPNExtendedReflexPage(YellowstonePathology.Business.Test.MPNExtendedReflex.PanelSetOrderMPNExtendedReflex testOrder,
YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
YellowstonePathology.Business.User.SystemIdentity systemIdentity) : base(testOrder, accessionOrder)
{
this.m_AccessionOrder = accessionOrder;
this.m_SystemIdentity = systemIdentity;
this.m_PanelSetOrder = testOrder;
Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(this.m_PanelSetOrder.OrderedOnId);
this.m_OrderedOnDescription = specimenOrder.Description;
this.m_PageHeaderText = this.m_PanelSetOrder.PanelSetName + " for: " + this.m_AccessionOrder.PatientDisplayName;
InitializeComponent();
this.DataContext = this;
this.m_ControlsNotDisabledOnFinal.Add(this.ButtonBack);
this.m_ControlsNotDisabledOnFinal.Add(this.ButtonFinish);
this.m_ControlsNotDisabledOnFinal.Add(this.TextBlockShowDocument);
this.m_ControlsNotDisabledOnFinal.Add(this.TextBlockUnfinalResults);
}
public static Business.Rules.MethodResult RemovePanelSet(string reportNo, Business.Test.AccessionOrder accessionOrder, object writer)
{
YellowstonePathology.Business.Rules.MethodResult methodResult = new Business.Rules.MethodResult();
if (accessionOrder.PanelSetOrderCollection.Count > 1)
{
Business.Test.PanelSetOrder panelSetOrder = accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(reportNo);
if ((accessionOrder.PLastName.ToUpper() == "MOUSE" && accessionOrder.PFirstName.ToUpper() == "MICKEY") ||
panelSetOrder.Final == false)
{
if (panelSetOrder.PanelSetId == 15)
{
//delete the thinprep slide;
if (accessionOrder.SpecimenOrderCollection.HasThinPrepFluidSpecimen() == true)
{
Business.Specimen.Model.SpecimenOrder specimenOrder = accessionOrder.SpecimenOrderCollection.GetThinPrep();
if (specimenOrder.AliquotOrderCollection.HasThinPrepSlide() == true)
{
Business.Test.AliquotOrder aliquotOrder = specimenOrder.AliquotOrderCollection.GetThinPrepSlide();
specimenOrder.AliquotOrderCollection.Remove(aliquotOrder);
}
}
}
accessionOrder.PanelSetOrderCollection.Remove(panelSetOrder);
accessionOrder.TaskOrderCollection.RemoveTaskOrdersForDeletedTestOrder(reportNo);
YellowstonePathology.Business.Persistence.DocumentGateway.Instance.Push(accessionOrder, writer);
}
else
{
methodResult.Success = false;
methodResult.Message = "Unable to remove a Panel Set that has been finaled.";
}
}
else
{
methodResult.Success = false;
methodResult.Message = "Unable to remove the only Panel Set for the Accession.";
}
return(methodResult);
}
public ErPrSemiQuantitativeResultPage(YellowstonePathology.Business.Test.ErPrSemiQuantitative.ErPrSemiQuantitativeTestOrder testOrder,
YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
YellowstonePathology.Business.User.SystemIdentity systemIdentity,
YellowstonePathology.UI.Navigation.PageNavigator pageNavigator) : base(testOrder, accessionOrder)
{
this.m_PanelSetOrder = testOrder;
this.m_AccessionOrder = accessionOrder;
this.m_SystemIdentity = systemIdentity;
this.m_PageNavigator = pageNavigator;
this.m_PageHeaderText = "Er/Pr Semi Quantitative Results For: " + this.m_AccessionOrder.PatientDisplayName + " (" + this.m_PanelSetOrder.ReportNo + ")";
this.m_SpecimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetByAliquotOrderId(this.m_PanelSetOrder.OrderedOnId);
YellowstonePathology.Business.Test.AliquotOrder aliquotOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetAliquotOrder(this.m_PanelSetOrder.OrderedOnId);
this.m_OrderedOnDescription = this.m_SpecimenOrder.Description + ": " + aliquotOrder.Label;
InitializeComponent();
DataContext = this;
this.m_ControlsNotDisabledOnFinal.Add(this.ButtonNext);
this.m_ControlsNotDisabledOnFinal.Add(this.TextBlockShowDocument);
this.m_ControlsNotDisabledOnFinal.Add(this.TextBlockUnfinalResults);
this.m_ControlsNotDisabledOnFinal.Add(this.TextBlockSetResults);
}
public string Build(Business.Test.AccessionOrder accessionOrder, string testOrderId, string slideOrderId)
{
//protoc -I d:/protogen --csharp_out d:/protogen/result d:/protogen/ventana.proto --grpc_out d:/protogen/result --plugin=protoc-gen-grpc=grpc_csharp_plugin.exe
Channel channel = new Channel("10.1.2.70:30051", ChannelCredentials.Insecure);
//Channel channel = new Channel("10.1.1.54:50051", ChannelCredentials.Insecure);
Ventana.VentanaService.VentanaServiceClient ventanaServiceClient = new Ventana.VentanaService.VentanaServiceClient(channel);
Ventana.OrderRequest orderRequest = new Ventana.OrderRequest();
Business.Test.PanelOrder panelOrder = accessionOrder.PanelSetOrderCollection.GetPanelOrderByTestOrderId(testOrderId);
Business.User.SystemUser orderedBy = Business.User.SystemUserCollectionInstance.Instance.SystemUserCollection.GetSystemUserById(panelOrder.OrderedById);
Business.Test.AliquotOrder aliquotOrder = accessionOrder.SpecimenOrderCollection.GetAliquotOrderByTestOrderId(testOrderId);
Business.Test.Model.TestOrder testOrder = panelOrder.TestOrderCollection.Get(testOrderId);
Business.Slide.Model.SlideOrder slideOrder = aliquotOrder.SlideOrderCollection.Get(slideOrderId);
Business.Specimen.Model.SpecimenOrder specimenOrder = accessionOrder.SpecimenOrderCollection.GetSpecimenOrderByAliquotOrderId(aliquotOrder.AliquotOrderId);
Business.Stain.Model.Stain stain = Business.Stain.Model.StainCollection.Instance.GetStainByTestId(testOrder.TestId);
string ventanaBarcode = stain.VentanaBenchMarkId.ToString();
string ventanaProtocolName = stain.VentanaBenchMarkProtocolName;
if (slideOrder.UseWetProtocol == true)
{
if (stain.HasWetProtocol == true)
{
ventanaBarcode = stain.VentanaBenchMarkWetId.ToString();
ventanaProtocolName = stain.VentanaBenchMarkWetProtocolName;
}
}
orderRequest.Msh = new Ventana.msh();
orderRequest.Msh.SendingApplication = "YPILIS";
orderRequest.Msh.SendingFacility = "YPI";
orderRequest.Msh.ReceivingApplication = "Ventana";
orderRequest.Msh.ReceivingFacility = "YPI";
orderRequest.Msh.DateTimeOfMessage = DateTime.Now.ToString("yyyyMMddHHmmss");
orderRequest.Msh.MessageType = "OML^O21";
orderRequest.Msh.MessageControlId = MongoDB.Bson.ObjectId.GenerateNewId().ToString();
orderRequest.Pid = new Ventana.pid();
orderRequest.Pid.FirstName = accessionOrder.PFirstName;
orderRequest.Pid.LastName = accessionOrder.PLastName;
orderRequest.Pid.MiddleInitial = string.IsNullOrEmpty(accessionOrder.PMiddleInitial) ? string.Empty : accessionOrder.PMiddleInitial;
orderRequest.Pid.Birthdate = accessionOrder.PBirthdate.Value.ToString("yyyyMMdd");
orderRequest.Pid.Sex = accessionOrder.PSex;
orderRequest.Pv1 = new Ventana.pv1();
orderRequest.Pv1.RequestingPhysicianFirstname = orderedBy.FirstName;
orderRequest.Pv1.RequestingPhysicianLastname = orderedBy.LastName;
orderRequest.Pv1.RequestingPhysicianNpi = string.IsNullOrEmpty(orderedBy.NationalProviderId) ? "NOTAPPLICABLE" : orderedBy.NationalProviderId;
orderRequest.Sac = new Ventana.sac();
orderRequest.Sac.RegistrationDateTime = accessionOrder.AccessionTime.Value.ToString("yyyyMMddHHmm");
Ventana.stain_order stainOrder = new Ventana.stain_order();
Ventana.orc orc = new Ventana.orc();
orc.OrderControl = "NW";
orc.PlacerOrderNumber = accessionOrder.MasterAccessionNo;
orc.SiteName = "YPI";
orc.SiteDescription = "Yellowstone Pathology";
orc.FacilityCode = "YPI";
orc.FacilityName = "Yellowstone Pathology";
stainOrder.Orc = orc;
Ventana.obr obr = new Ventana.obr();
obr.OrderSequenceId = "1";
obr.PlacerOrderNumber = accessionOrder.MasterAccessionNo;
obr.ProtocolNumber = ventanaBarcode;
obr.ProtocolName = ventanaProtocolName;
obr.OrderType = "STAIN";
obr.ObservationDateTime = DateTime.Now.ToString("yyyyMMddHHmm");
if (string.IsNullOrEmpty(specimenOrder.SpecimenId) == false)
{
obr.SpecimenName = specimenOrder.SpecimenId;
}
else
{
obr.SpecimenName = "NONE";
}
obr.SpecimenDescription = specimenOrder.Description;
obr.SurgicalProcedureName = "Surgical Pathology";
obr.PathologistNpi = string.IsNullOrEmpty(orderedBy.NationalProviderId) ? "NOTAPPLICABLE" : orderedBy.NationalProviderId;
obr.PathologistLastname = orderedBy.LastName;
obr.PathologistFirstname = orderedBy.FirstName;
obr.SlideId = "HSLD" + slideOrder.SlideOrderId;
obr.SlideSequence = Business.Specimen.Model.Slide.GetSlideNumber(slideOrder.Label);
obr.Blockid = aliquotOrder.AliquotOrderId;
obr.BlockSequence = Business.Specimen.Model.Block.GetBlockLetter(aliquotOrder.Label);
obr.SpecimenId = specimenOrder.SpecimenOrderId;
obr.SpecimenSequence = specimenOrder.SpecimenNumber.ToString();
stainOrder.Obr = obr;
orderRequest.StainOrders.Add(stainOrder);
Ventana.OrderReply orderReply = ventanaServiceClient.buildOrder(orderRequest);
return(orderReply.Message);
}
public override void SetSummaryResults(Business.Specimen.Model.SpecimenOrder specimenOrder)
{
this.m_ResultComment = null;
this.m_ResultDescription = "Ratio = " + this.m_HER2AnalysisSummaryTestOrder.Her2Chr17Ratio;
base.SetSummaryResults(specimenOrder);
}
public override void SetISHResults(Business.Specimen.Model.SpecimenOrder specimenOrder)
{
this.m_ResultComment = null;
this.m_ResultDescription = "Ratio = " + this.m_HER2AmplificationByISHTestOrder.Her2Chr17Ratio;
base.SetISHResults(specimenOrder);
}
public void SetResults(ErPrSemiQuantitativeTestOrder panelSetOrderErPrSemiQuantitative, Business.Specimen.Model.SpecimenOrder specimenOrder)
{
panelSetOrderErPrSemiQuantitative.ResultCode = this.m_ResultCode;
panelSetOrderErPrSemiQuantitative.ReportReferences = this.m_ReportReferences;
panelSetOrderErPrSemiQuantitative.Method = this.m_Method;
panelSetOrderErPrSemiQuantitative.Interpretation = this.m_Interpretation;
if (specimenOrder.FixationDuration > 72 || specimenOrder.FixationDuration < 6)
{
specimenOrder.FixationComment = m_FixationOutOfBoundsComment;
}
}
