public void BinaryContingencyNullTest()
        {
            BinaryContingencyTable e0 = CreateExperiment(0.25, 0.33, 0.33, 200);

            Assert.IsTrue(e0.Total == 200);
            Assert.IsTrue(e0.RowTotal(0) + e0.RowTotal(1) == e0.Total);
            Assert.IsTrue(e0.ColumnTotal(0) + e0.ColumnTotal(1) == e0.Total);

            UncertainValue lnr = e0.LogOddsRatio;

            Assert.IsTrue(lnr.ConfidenceInterval(0.95).ClosedContains(0.0));

            UncertainValue r = e0.OddsRatio;

            Assert.IsTrue(r.ConfidenceInterval(0.95).ClosedContains(1.0));

            TestResult f = e0.FisherExactTest();

            Assert.IsTrue(f.RightProbability < 0.95, f.RightProbability.ToString());
        }
        private static BinaryContingencyTable CreateExperiment(double p, double q0, double q1, int N)
        {
            BinaryContingencyTable e = new BinaryContingencyTable();

            Random rng = new Random(1);

            for (int i = 0; i < N; i++)
            {
                int r, c;
                if (rng.NextDouble() < p)
                {
                    r = 0;
                    if (rng.NextDouble() < q0)
                    {
                        c = 0;
                    }
                    else
                    {
                        c = 1;
                    }
                }
                else
                {
                    r = 1;
                    if (rng.NextDouble() < q1)
                    {
                        c = 0;
                    }
                    else
                    {
                        c = 1;
                    }
                }
                e[r, c] += 1;
            }


            return(e);
        }
        public void BinaryContingencyTest()
        {
            BinaryContingencyTable e1 = CreateExperiment(0.50, 0.50, 0.75, 200);

            Assert.IsTrue(e1.RowTotal(0) + e1.RowTotal(1) == e1.Total);
            Assert.IsTrue(e1.ColumnTotal(0) + e1.ColumnTotal(1) == e1.Total);

            UncertainValue lnr = e1.LogOddsRatio;

            Assert.IsFalse(lnr.ConfidenceInterval(0.95).ClosedContains(0.0));

            UncertainValue r = e1.OddsRatio;

            Assert.IsFalse(r.ConfidenceInterval(0.95).ClosedContains(1.0));

            TestResult p = e1.PearsonChiSquaredTest();

            Assert.IsTrue(p.LeftProbability > 0.95, p.RightProbability.ToString());

            TestResult f = e1.FisherExactTest();

            Assert.IsTrue(f.RightProbability > 0.95);
        }
示例#4
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        private Dictionary <string, double> FisherExactTest(Dictionary <string, int> background, Dictionary <string, int> test)
        {
            Dictionary <string, double> pvalueDict = new Dictionary <string, double>();

            int totalBackground = background.Values.Sum();
            int totalTest       = test.Values.Sum();

            foreach (KeyValuePair <string, int> kvp in test)
            {
                int backgroundCount = background[kvp.Key];
                int testCount       = kvp.Value;

                BinaryContingencyTable table = new BinaryContingencyTable();

                //I got this from Doug's code. I hope it is right.
                int upperleft  = testCount;
                int upperright = backgroundCount - upperleft;
                int lowerleft  = totalTest - upperleft;
                int lowerright = totalBackground - totalTest - upperright;

                table[0, 0] = upperleft;
                table[0, 1] = upperright;
                table[1, 0] = lowerleft;
                table[1, 1] = lowerright;

                TestResult fisherExactResult = table.FisherExactTest();

                double pvalueLeft  = fisherExactResult.LeftProbability;
                double pvalueRight = fisherExactResult.LeftProbability;

                pvalueDict.Add(kvp.Key, pvalueRight);
            }

            Dictionary <string, double> qvalueDict = BenjaminiHochberg(pvalueDict);

            return(qvalueDict);
        }
 public void BinaryContingencyInvalidConstructionTest()
 {
     int[,] M = new int[2, 3];
     BinaryContingencyTable t = new BinaryContingencyTable(M);
 }
 public void BCT()
 {
     BinaryContingencyTable B = new BinaryContingencyTable();
 }