protected override async Task Context()
{
await base.Context();
_project = new PKSimProject();
_newIndividual = new Individual
{
OriginData = new OriginData()
};
_newAgeRange = new ParameterRange {
ParameterName = CoreConstants.Parameters.AGE
};
_newWeightRange = new ParameterRange {
ParameterName = CoreConstants.Parameters.MEAN_WEIGHT
};
_snapshot = await sut.MapToSnapshot(_randomPopulationSettings);
_snapshot.ProportionOfFemales = _proportionOfFemale;
A.CallTo(() => _parameterRangeMapper.MapToModel(_snapshot.Age, A <ParameterRangeSnapshotContext> .That.Matches(x => x.ParameterRange == _newAgeRange))).Returns(_newAgeRange);
A.CallTo(() => _parameterRangeMapper.MapToModel(_snapshot.Weight, A <ParameterRangeSnapshotContext> .That.Matches(x => x.ParameterRange == _newWeightRange))).Returns(_newWeightRange);
A.CallTo(() => _individualMapper.MapToModel(_snapshotIndividual, _snapshotContext)).Returns(_newIndividual);
_newDiseaseStateParameterRange = new ConstrainedParameterRange {
ParameterName = _diseaseStateParameter.Name
};
_mappedSettings = new RandomPopulationSettings {
BaseIndividual = _newIndividual
};
_mappedSettings.AddParameterRange(_newDiseaseStateParameterRange);
A.CallTo(() => _populationSettingsMapper.MapFrom(_newIndividual)).Returns(_mappedSettings);
}
public virtual ParameterRange Clone()
{
var clone = new ParameterRange();
clone.UpdatePropertiesFrom(this, null);
return(clone);
}
private static bool maxGreaterThanMin(ParameterRange param, double?maxValueInDisplayUnit)
{
if (doesNotNeedCheck(param.MinValue, maxValueInDisplayUnit))
{
return(true);
}
return(param.baseValueFrom(maxValueInDisplayUnit) >= param.MinValue);
}
private static bool minLessThanDbMax(ParameterRange param, double?minValueInDisplayUnit)
{
if (doesNotNeedCheck(param.DbMaxValue, minValueInDisplayUnit))
{
return(true);
}
return(param.baseValueFrom(minValueInDisplayUnit) <= param.DbMaxValue);
}
private double tryCreateRandomValueFor(ParameterRange parameterRange, IParameter baseParameter, out bool success)
{
try
{
success = true;
if (parameterRange.IsConstant)
{
return(parameterRange.MinValue.Value);
}
return(baseParameter.RandomDeviateIn(_randomGenerator, parameterRange.MinValue, parameterRange.MaxValue));
}
catch (DistributionException)
{
success = false;
return(baseParameter.Value);
}
}
protected override Task Context()
{
_individualMapper = A.Fake <IndividualMapper>();
_parameterRangeMapper = A.Fake <ParameterRangeMapper>();
_genderRepository = A.Fake <IGenderRepository>();
_populationSettingsMapper = A.Fake <IIndividualToPopulationSettingsMapper>();
sut = new RandomPopulationSettingsMapper(_parameterRangeMapper, _individualMapper, _populationSettingsMapper, _genderRepository);
_ageParameterRange = new ConstrainedParameterRange {
ParameterName = CoreConstants.Parameters.AGE
};
_weightParameterRange = new ParameterRange {
ParameterName = CoreConstants.Parameters.MEAN_WEIGHT
};
A.CallTo(() => _parameterRangeMapper.MapToSnapshot(null)).Returns((Snapshots.ParameterRange)null);
_ageRangeSnapshot = new Snapshots.ParameterRange();
A.CallTo(() => _parameterRangeMapper.MapToSnapshot(_ageParameterRange)).Returns(_ageRangeSnapshot);
_weightRangeSnapshot = new Snapshots.ParameterRange();
A.CallTo(() => _parameterRangeMapper.MapToSnapshot(_weightParameterRange)).Returns(_weightRangeSnapshot);
_baseIndividual = new Individual();
_snapshotIndividual = new Snapshots.Individual();
A.CallTo(() => _individualMapper.MapToSnapshot(_baseIndividual)).Returns(_snapshotIndividual);
_randomPopulationSettings = new RandomPopulationSettings
{
NumberOfIndividuals = 10,
BaseIndividual = _baseIndividual
};
_randomPopulationSettings.AddParameterRange(_weightParameterRange);
_randomPopulationSettings.AddParameterRange(_ageParameterRange);
A.CallTo(() => _genderRepository.Female).Returns(new Gender {
Id = "Female", Name = "Female"
});
A.CallTo(() => _genderRepository.Male).Returns(new Gender {
Id = "Male", Name = "Male"
});
return(Task.FromResult(true));
}
protected override async Task Context()
{
await base.Context();
_newIndividual = new Individual();
_newAgeRange = new ParameterRange {
ParameterName = CoreConstants.Parameters.AGE
};
_newWeightRange = new ParameterRange {
ParameterName = CoreConstants.Parameters.MEAN_WEIGHT
};
_snapshot = await sut.MapToSnapshot(_randomPopulationSettings);
_snapshot.ProportionOfFemales = _proportionOfFemale;
A.CallTo(() => _parameterRangeMapper.MapToModel(_snapshot.Age, A <ParameterRangeSnapshotContext> .That.Matches(x => x.ParameterRange == _newAgeRange))).Returns(_newAgeRange);
A.CallTo(() => _parameterRangeMapper.MapToModel(_snapshot.Weight, A <ParameterRangeSnapshotContext> .That.Matches(x => x.ParameterRange == _newWeightRange))).Returns(_newWeightRange);
A.CallTo(() => _individualMapper.MapToModel(_snapshotIndividual, _snapshotContext)).Returns(_newIndividual);
_mappedSettings = new RandomPopulationSettings();
A.CallTo(() => _populationSettingsMapper.MapFrom(_newIndividual)).Returns(_mappedSettings);
_mappedSettings.AddParameterRange(_newAgeRange);
_mappedSettings.AddParameterRange(_newWeightRange);
_maleRatio = new GenderRatio
{
Gender = _genderRepository.Male,
Ratio = 50
};
_femaleRatio = new GenderRatio
{
Gender = _genderRepository.Female,
Ratio = 50
};
_mappedSettings.AddGenderRatio(_maleRatio);
_mappedSettings.AddGenderRatio(_femaleRatio);
_snapshot.DiseaseStateParameters = null;
}
public void AddParameterRange(ParameterRange parameterRange) => _parameterRanges.Add(parameterRange);
protected override Task Context()
{
_individualMapper = A.Fake <IndividualMapper>();
_parameterRangeMapper = A.Fake <ParameterRangeMapper>();
_genderRepository = A.Fake <IGenderRepository>();
_populationSettingsMapper = A.Fake <IIndividualToPopulationSettingsMapper>();
_logger = A.Fake <IOSPSuiteLogger>();
sut = new RandomPopulationSettingsMapper(_parameterRangeMapper, _individualMapper, _populationSettingsMapper, _genderRepository, _logger);
_ageParameterRange = new ConstrainedParameterRange {
ParameterName = CoreConstants.Parameters.AGE
};
_weightParameterRange = new ParameterRange {
ParameterName = CoreConstants.Parameters.MEAN_WEIGHT
};
A.CallTo(() => _parameterRangeMapper.MapToSnapshot(null)).Returns((Snapshots.ParameterRange)null);
_ageRangeSnapshot = new Snapshots.ParameterRange();
A.CallTo(() => _parameterRangeMapper.MapToSnapshot(_ageParameterRange)).Returns(_ageRangeSnapshot);
_weightRangeSnapshot = new Snapshots.ParameterRange();
A.CallTo(() => _parameterRangeMapper.MapToSnapshot(_weightParameterRange)).Returns(_weightRangeSnapshot);
_baseIndividual = new Individual
{
OriginData = new OriginData()
};
_diseaseStateParameter = new OriginDataParameter(10, "mg/kg", "DIS_STATE_PARAM");
_baseIndividual.OriginData.AddDiseaseStateParameter(_diseaseStateParameter);
_diseaseStateParameterRangeSnapshot = new Snapshots.ParameterRange();
_diseaseStateParameterRange = new ConstrainedParameterRange {
ParameterName = _diseaseStateParameter.Name
};
A.CallTo(() => _parameterRangeMapper.MapToSnapshot(_diseaseStateParameterRange)).Returns(_diseaseStateParameterRangeSnapshot);
_snapshotIndividual = new Snapshots.Individual();
A.CallTo(() => _individualMapper.MapToSnapshot(_baseIndividual)).Returns(_snapshotIndividual);
_randomPopulationSettings = new RandomPopulationSettings
{
NumberOfIndividuals = 10,
BaseIndividual = _baseIndividual
};
_randomPopulationSettings.AddParameterRange(_weightParameterRange);
_randomPopulationSettings.AddParameterRange(_ageParameterRange);
_randomPopulationSettings.AddParameterRange(_diseaseStateParameterRange);
A.CallTo(() => _genderRepository.Female).Returns(new Gender {
Id = "Female", Name = "Female"
});
A.CallTo(() => _genderRepository.Male).Returns(new Gender {
Id = "Male", Name = "Male"
});
_project = new PKSimProject();
_snapshotContext = new SnapshotContext(_project, ProjectVersions.Current);
return(Task.FromResult(true));
}
