public HomePage(string ProteinName = "", string AminoSeq = "")
{
aminoClass = new AminoAcids();
InitializeComponent();
//creating tool bar item
var toolbar = new ToolbarItem();
toolbar.AutomationId = "RunAnalysisItem";
toolbar.Text = "Evaluate Structure";
toolbar.Priority = 1;
toolbar.Clicked += new EventHandler(RunAnalysisItem_Click);
toolbar.Order = ToolbarItemOrder.Primary;
// creating a second toolbar item
var toolbar2 = new ToolbarItem();
toolbar2.AutomationId = "PreviousEntriesItem";
toolbar2.Text = "Previous Entries";
toolbar2.Priority = 1;
// navigate to new page when clicked
toolbar2.Clicked += delegate
{
Navigation.PushAsync(new PreviousEntries());
};
toolbar2.Order = ToolbarItemOrder.Primary;
// add tool bar items
this.ToolbarItems.Add(toolbar);
this.ToolbarItems.Add(toolbar2);
// if the contructor isn't empty, create a helical wheel
if (!string.IsNullOrEmpty(AminoSeq))
{
ProteinEntry.Text = ProteinName;
AminoAcidEditor.Text = AminoSeq;
DrawHelicalWheel();
}
}
public void HelicalWheelBuilderThreeLetter(string aminoAcids, SKCanvas canvas)
{
var aminoClass = new AminoAcids();
var listAminos = aminoAcids.Split(',').ToList();
float xval = 0; float yval = 0;
float xModifier = 0; float yModifier = 0;
float modIncrementer = 0;
float scaleModifier = 19;
int angle = 270;
bool polarity = false;
string lastAmino = "";
int incr = 1;
var percentDiff = (App.ScreenHeight / ScaleFactor);
foreach (var item in listAminos)
{
if (!string.IsNullOrWhiteSpace(item))
{
if (!string.IsNullOrWhiteSpace(lastAmino))
{
if (incr < 18)
{
canvas.DrawLine(xval, yval, (float)((RADIUS * percentDiff) * Math.Cos(angle * Math.PI / 180F)), (float)((RADIUS * percentDiff) * Math.Sin(angle * Math.PI / 180F)), Line);
}
if (polarity)
{
canvas.DrawText(lastAmino.Substring(0, 1).ToString().ToUpper() + lastAmino.Substring(1, 2) + incr, xval - 7, yval + 4, PolarLetters);
}
else
{
canvas.DrawText(lastAmino.Substring(0, 1).ToString().ToUpper() + lastAmino.Substring(1, 2) + incr, xval - 7, yval + 4, NonPolarLetters);
}
incr += 1;
}
xval = (float)((RADIUS * percentDiff) * Math.Cos(angle * Math.PI / 180F));
yval = (float)((RADIUS * percentDiff) * Math.Sin(angle * Math.PI / 180F));
HelicalStructure.Add(new KeyValuePair <string, Point>(item.Substring(0, 1).ToString().ToUpper() + item.Substring(1, 2) + incr, new Point(xval, yval)));
if (incr % scaleModifier == 0)
{
modIncrementer += 1;
scaleModifier = scaleModifier + 18;
}
xModifier = xval > 0 ? 13f * modIncrementer : -13f * modIncrementer;
yModifier = yval > 0 ? 13f * modIncrementer : -13f * modIncrementer;
if (Math.Abs(xval) < 5 && modIncrementer > 0)
{
yModifier = yModifier > 0 ? (yModifier - .5f) + (6 * modIncrementer) : (yModifier + .5f) - (6 * modIncrementer);
xModifier = 0;
}
xval += xModifier;
yval += yModifier;
if (aminoClass.IsAminoAcid(item))
{
if (polarity = aminoClass.IsPolar(item))
{
canvas.DrawCircle(xval, yval, (AMINORADIUS * percentDiff), PolarAminoAcid);
}
else
{
canvas.DrawCircle(xval, yval, (AMINORADIUS * percentDiff), NonPolarAminoAcid);
}
}
else
{
canvas.DrawCircle(xval, yval, (AMINORADIUS * percentDiff), InvalidAminoAcid);
}
angle += 100;
if (angle > 360)
{
angle -= 360;
}
lastAmino = item;
}
}
if (!string.IsNullOrWhiteSpace(lastAmino))
{
if (polarity)
{
canvas.DrawText(lastAmino.Substring(0, 1).ToString().ToUpper() + lastAmino.Substring(1, 2) + incr, xval - 7, yval + 4, PolarLetters);
}
else
{
canvas.DrawText(lastAmino.Substring(0, 1).ToString().ToUpper() + lastAmino.Substring(1, 2) + incr, xval - 7, yval + 4, NonPolarLetters);
}
}
}
public void HelicalWheelBuilderLetter(string aminoAcids, SKCanvas canvas)
{
// init. my variables
var aminoClass = new AminoAcids();
var listAminos = aminoAcids.ToCharArray().ToList();
float x = 0; float y = 0;
int angle = 270;
char lastChar = '0';
bool polarity = false;
float xModifier = 0;
float yModifier = 0;
float modIncrementer = 0;
float scaleModifier = 19;
int incr = 1;
var percentDiff = (App.ScreenHeight / ScaleFactor);
// iterate over the amino acids
foreach (var item in listAminos)
{
// if its a valid character
if (char.IsLetter(item))
{
// acheck to make sure to add the
if (lastChar != '0')
{
//draw line
if (incr < 18)
{
canvas.DrawLine(x, y, (float)((RADIUS * percentDiff) * Math.Cos(angle * Math.PI / 180F)), (float)((RADIUS * percentDiff) * Math.Sin(angle * Math.PI / 180F)), Line);
}
// check if polar or not then draw the circle accordingly
if (polarity)
{
canvas.DrawText(lastChar.ToString().ToUpper() + incr, x - 6, y + 4, PolarLetters);
}
else
{
canvas.DrawText(lastChar.ToString().ToUpper() + incr, x - 6, y + 4, NonPolarLetters);
}
incr += 1;
}
// determine the x & y coordinates using this formula
x = (float)((RADIUS * percentDiff) * Math.Cos(angle * Math.PI / 180F));
y = (float)((RADIUS * percentDiff) * Math.Sin(angle * Math.PI / 180F));
// add x & y coordinates to my global variable
HelicalStructure.Add(new KeyValuePair <string, Point>(item.ToString().ToUpper() + incr, new Point(x, y)));
if (incr % scaleModifier == 0)
{
modIncrementer += 1;
scaleModifier = scaleModifier + 18;
}
xModifier = x > 0? 13f * modIncrementer : -13f * modIncrementer;
yModifier = y > 0? 13f * modIncrementer : -13f * modIncrementer;
if (Math.Abs(x) < 5 && modIncrementer > 0)
{
yModifier = yModifier > 0 ? (yModifier - .5f) + (6 * modIncrementer) : (yModifier + .5f) - (6 * modIncrementer);
xModifier = 0;
}
x += xModifier;
y += yModifier;
if (aminoClass.IsAminoAcid(null, item))
{
if (polarity = aminoClass.IsPolar(null, item))
{
canvas.DrawCircle(x, y, (AMINORADIUS * percentDiff), PolarAminoAcid);
}
else
{
canvas.DrawCircle(x, y, (AMINORADIUS * percentDiff), NonPolarAminoAcid);
}
}
else
{
canvas.DrawCircle(x, y, (AMINORADIUS * percentDiff), InvalidAminoAcid);
}
angle += 100;
if (angle > 360)
{
angle -= 360;
}
lastChar = item;
}
}
if (char.IsLetter(lastChar))
{
if (polarity)
{
canvas.DrawText(lastChar.ToString().ToUpper() + incr, x - 6, y + 4, PolarLetters);
}
else
{
canvas.DrawText(lastChar.ToString().ToUpper() + incr, x - 6, y + 4, NonPolarLetters);
}
}
}
