Пример #1
0
 /// <summary>
 /// Step 1: Building k-mers from sequence reads
 /// Step 2: Build de bruijn graph for input set of k-mers.
 /// Sets the _assemblerGraph field.
 /// </summary>
 protected virtual void CreateGraph()
 {
     Graph = new DeBruijnGraph(this.kmerLength);
     Graph.Build(this.sequenceReads);
 }
Пример #2
0
        /// <summary>
        /// Validate graph generated using DeBruijnGraph.CreateGraph() with kmers
        /// </summary>
        /// <param name="nodeName">xml node name used for different testcases</param>
        internal void ValidateDeBruijnGraphBuild(string nodeName)
        {
            string filePath = utilityObj.xmlUtil.GetTextValue(nodeName, Constants.FilePathNode);
            string kmerLength = utilityObj.xmlUtil.GetTextValue(nodeName, Constants.KmerLengthNode);

            // Get the input reads and build kmers
            IEnumerable<ISequence> sequenceReads = null;
            using (FastAParser parser = new FastAParser(filePath))
            {
                sequenceReads = parser.Parse();

                this.KmerLength = int.Parse(kmerLength, (IFormatProvider)null);
                this.SequenceReads.Clear();
                this.SetSequenceReads(sequenceReads.ToList());
                DeBruijnGraph graph = new DeBruijnGraph(this.KmerLength);
                graph.Build(this.SequenceReads);
                ValidateGraph(graph, nodeName);
            }
            ApplicationLog.WriteLine(@"Padena BVT : DeBruijnGraph Build() validation for Padena step2 completed successfully");

        }