private void addPKParametersForOutput(
IModelCoreSimulation simulation,
SimulationResults simulationResults,
Action <int> performIndividualScalingAction,
QuantitySelection selectedQuantity,
PopulationSimulationPKAnalyses popAnalyses,
string moleculeName,
PKCalculationOptions pkCalculationOptions,
IReadOnlyList <ApplicationParameters> allApplicationParameters)
{
var allPKParameters = _pkParameterRepository.All().Where(p => PKParameterCanBeUsed(p, pkCalculationOptions)).ToList();
var allUserDefinedPKParameters = allPKParameters.OfType <UserDefinedPKParameter>().ToList();
//create pk parameter for each pk parameters (predefined and dynamic)
foreach (var pkParameter in allPKParameters)
{
var quantityPKParameter = new QuantityPKParameter {
Name = pkParameter.Name, QuantityPath = selectedQuantity.Path, Dimension = pkParameter.Dimension
};
popAnalyses.AddPKAnalysis(quantityPKParameter);
}
//add the values for each individual
foreach (var individualResult in simulationResults.AllIndividualResults)
{
performIndividualScalingAction(individualResult.IndividualId);
_pkCalculationOptionsFactory.UpdateTotalDrugMassPerBodyWeight(simulation, moleculeName, pkCalculationOptions, allApplicationParameters);
var values = individualResult.QuantityValuesFor(selectedQuantity.Path);
//This can happen is the results do not match the simulation
if (values == null)
{
continue;
}
var pkValues = _pkValuesCalculator.CalculatePK(individualResult.Time.Values, values.Values, pkCalculationOptions, allUserDefinedPKParameters);
foreach (var quantityPKParameter in popAnalyses.AllPKParametersFor(selectedQuantity.Path))
{
quantityPKParameter.SetValue(individualResult.IndividualId, pkValues.ValueOrDefaultFor(quantityPKParameter.Name));
}
}
}
public void should_not_crash()
{
_results.AllPKParametersFor(_quantityPath1).Count.ShouldBeEqualTo(2);
}
public void should_have_created_one_pk_analyses_for_each_output_defined_in_the_simulation()
{
_results.AllPKParametersFor(_quantityPath1).Count.ShouldBeEqualTo(2);
_results.AllPKParametersFor(_quantityPath2).Count.ShouldBeEqualTo(2);
}
