/// <summary>
/// Normalize the plan such that V100%Rx is at least 98%.
/// </summary>
public static void Normalize(ExternalPlanSetup plan, Dictionary <string, ModelStructure> structureMatches)
{
var ptvId = structureMatches.Single(x => x.Value.ModelId == "PTV").Key;
var ptv = plan.StructureSet.Structures.Single(st => st.Id == ptvId);
plan.PlanNormalizationValue = 100.0;
const double relativeDose = 100;
const double volTarget = 98.0;
var targetDose = plan.TotalPrescribedDose.Dose;
var dv = new DoseValue((relativeDose / 100.0) * targetDose, "Gy");
var vol = plan.GetVolumeAtDose(ptv, dv, VolumePresentation.Relative);
if (vol < volTarget)
{
dv = plan.GetDoseAtVolume(ptv, volTarget, VolumePresentation.Relative, DoseValuePresentation.Absolute);
plan.PlanNormalizationValue = 100.0 * dv.Dose / ((relativeDose / 100.0) * targetDose);
}
}
public bool runCoverageCheck(List <Tuple <string, string, double, double, int> > optParams, ExternalPlanSetup plan, int percentCompletion, double relativeDose, double targetVolCoverage, bool useFlash)
{
//zero all optimization objectives except those in the target
List <Tuple <string, string, double, double, int> > targetOnlyObj = new List <Tuple <string, string, double, double, int> > {
};
int priority;
string message = optObjHeader;
foreach (Tuple <string, string, double, double, int> opt in optParams)
{
if (opt.Item1.ToLower().Contains("ptv") || opt.Item1.ToLower().Contains("ts_jnx"))
{
priority = opt.Item5;
}
else
{
priority = 0;
}
targetOnlyObj.Add(Tuple.Create(opt.Item1, opt.Item2, opt.Item3, opt.Item4, priority));
//record the optimization constraints for each structure after zero-ing the priorities. This information will be reported to the user in a progress update
message += String.Format(" {0, -15} | {1, -16} | {2,-10:N1} | {3,-10:N1} | {4,-8} |" + System.Environment.NewLine, opt.Item1, opt.Item2, opt.Item3, opt.Item4, priority);
}
//update the constraints and provide an update to the user
op.updateConstraints(targetOnlyObj, plan);
Dispatcher.BeginInvoke((Action)(() => { provideUpdate((int)(100 * (++percentCompletion) / calcItems), message); }));
//run one optimization with NO intermediate dose.
plan.OptimizeVMAT(new OptimizationOptionsVMAT(OptimizationIntermediateDoseOption.NoIntermediateDose, MLCmodel));
if (abortOpt)
{
return(false);
}
//provide update
Dispatcher.BeginInvoke((Action)(() => { provideUpdate((int)(100 * (++percentCompletion) / calcItems), " Optimization finished on coverage check! Calculating dose!"); }));
Dispatcher.BeginInvoke((Action)(() => { provideUpdate(String.Format(" Elapsed time: {0}", currentTime)); }));
//calculate dose (using AAA algorithm)
plan.CalculateDose();
if (abortOpt)
{
return(false);
}
Dispatcher.BeginInvoke((Action)(() => { provideUpdate((int)(100 * (++percentCompletion) / calcItems), " Dose calculated for coverage check, normalizing plan!"); }));
//normalize plan
op.normalizePlan(plan, relativeDose, targetVolCoverage, useFlash);
if (abortOpt)
{
return(false);
}
Dispatcher.BeginInvoke((Action)(() => { provideUpdate((int)(100 * (++percentCompletion) / calcItems), " Plan normalized!"); }));
//print useful info about target coverage and global dmax
Structure target;
if (useFlash)
{
target = plan.StructureSet.Structures.First(x => x.Id.ToLower() == "ts_ptv_flash");
}
else
{
target = plan.StructureSet.Structures.First(x => x.Id.ToLower() == "ts_ptv_vmat");
}
message = " Additional plan infomation: " + System.Environment.NewLine +
String.Format(" Plan global Dmax = {0:0.0}%", 100 * (plan.Dose.DoseMax3D.Dose / plan.TotalDose.Dose)) + System.Environment.NewLine +
String.Format(" {0} Dmax = {1:0.0}%", target.Id, plan.GetDoseAtVolume(target, 0.0, VolumePresentation.Relative, DoseValuePresentation.Relative).Dose) + System.Environment.NewLine +
String.Format(" {0} Dmin = {1:0.0}%", target.Id, plan.GetDoseAtVolume(target, 100.0, VolumePresentation.Relative, DoseValuePresentation.Relative).Dose) + System.Environment.NewLine +
String.Format(" {0} V90% = {1:0.0}%", target.Id, plan.GetVolumeAtDose(target, new DoseValue(90.0, DoseValue.DoseUnit.Percent), VolumePresentation.Relative)) + System.Environment.NewLine +
String.Format(" {0} V110% = {1:0.0}%", target.Id, plan.GetVolumeAtDose(target, new DoseValue(110.0, DoseValue.DoseUnit.Percent), VolumePresentation.Relative)) + System.Environment.NewLine +
String.Format(" {0} V120% = {1:0.0}%", target.Id, plan.GetVolumeAtDose(target, new DoseValue(120.0, DoseValue.DoseUnit.Percent), VolumePresentation.Relative));
Dispatcher.BeginInvoke((Action)(() => { provideUpdate(message); }));
//calculate global Dmax expressed as a percent of the prescription dose (if dose has been calculated)
if (plan.IsDoseValid && ((plan.Dose.DoseMax3D.Dose / plan.TotalDose.Dose) > 1.40))
{
return(true);
}
//else MessageBox.Show(String.Format("max dose: {0}%", 100 * (plan.Dose.DoseMax3D.Dose / plan.TotalDose.Dose)));
return(false);
}
static void Planning(Application curapp, Patient curpat, StructureSet curstructset, List <Tuple <string, string, float, string> > TargetStructures, List <string> AllowedNonTargetStructures, float RxDose, int NFractions)
{
curpat.BeginModifications();
string IDofptv_low = string.Empty;
string IDofptv_high = string.Empty; //
StringBuilder sb = new StringBuilder();
//Check structure nameing
sb.AppendLine("Check Structure Naming");
sb.AppendLine("Structure ID \tIs Standard Name?");
foreach (Structure curstruct in curstructset.Structures.OrderBy(x => x.Id))
{
if (curstruct.DicomType == "PTV" | curstruct.DicomType == "CTV" | curstruct.DicomType == "GTV")
{
if (TargetStructures.Where(x => x.Item1 == curstruct.Id).Any() || TargetStructures.Where(x => curstruct.DicomType.ToString() + "_" + x.Item3 + (x.Item4 == "Gy" ? "00" : string.Empty) == curstruct.Id).Any())
{
sb.AppendLine(curstruct.Id.PadRight(curstruct.Id.Length < 20 ? 20 - curstruct.Id.Length : 0) + "\tYes");
}
else
{
sb.AppendLine(curstruct.Id.PadRight(curstruct.Id.Length < 20 ? 20 - curstruct.Id.Length : 0) + "\tNo");
}
}
else
{
if (AllowedNonTargetStructures.Where(x => x == curstruct.Id).Any() || curstruct.Id.ToString().StartsWith("z"))
{
sb.AppendLine(curstruct.Id.PadRight(curstruct.Id.Length < 20 ? 20 - curstruct.Id.Length : 0) + "\tYes");
}
else
{
sb.AppendLine(curstruct.Id.PadRight(curstruct.Id.Length < 20 ? 20 - curstruct.Id.Length : 0) + "\tNo");
}
}
}
sb.AppendLine();
sb.AppendLine("Press OK to continue with creating optimization structures");
System.Windows.MessageBox.Show(sb.ToString());
//Create optimization structures
if (TargetStructures.Where(x => x.Item1 == "PTV_Low").Any())
{
IDofptv_low = TargetStructures.Where(x => x.Item1 == "PTV_Low").Select(x => x.Item2).First(); //Get the ID of the structure identified as PTV_Low
}
if (TargetStructures.Where(x => x.Item1 == "PTV_High").Any())
{
IDofptv_high = TargetStructures.Where(x => x.Item1 == "PTV_High").Select(x => x.Item2).First(); //Get the ID of the structure identified as PTV_High
}
Structure ptv_low = null;
Structure ptv_high = null;
//Check that PT_High structure exists, issue warning if it does not.
if (curstructset.Structures.Where(x => x.Id == IDofptv_low).Any())
{
ptv_low = curstructset.Structures.Where(x => x.Id == IDofptv_low).First();
}
else
{
System.Windows.MessageBox.Show("Did not find a PTV_High Structure. Fix before proceeding");
}
//Check that PT_Low structure exists, issue warning if it does not.
if (curstructset.Structures.Where(x => x.Id == IDofptv_high).Any())
{
ptv_high = curstructset.Structures.Where(x => x.Id == IDofptv_high).First();
}
else
{
System.Windows.MessageBox.Show("Did not find a PTV_Low Structure. Fix before proceeding");
}
//Creation of optimization structures. If a copy already exitst delete it first.
//Optimization structure for the PTV_Low volume is named zPTV_Low^Opt
if (curstructset.Structures.Where(x => x.Id.Contains("zPTV_Low^Opt")).Any())
{
curstructset.RemoveStructure(curstructset.Structures.Where(x => x.Id.Contains("zPTV_Low^Opt")).First());
}
Structure zptvlowopt = curstructset.AddStructure("ORGAN", "zPTV_Low^Opt");
//Dose limiting annulus (DLA) structure is used to make the prescribed dose conformal. DLA for PTV_Low is named zDLA_Low
if (curstructset.Structures.Where(x => x.Id.Contains("zDLA__Low")).Any())
{
curstructset.RemoveStructure(curstructset.Structures.Where(x => x.Id.Contains("zDLA__Low")).First());
}
Structure zdlalow = curstructset.AddStructure("ORGAN", "zDLA__Low");
//Optimization structure for the PTV_High volume is named zPTV_High^Opt
if (curstructset.Structures.Where(x => x.Id.Contains("zPTV_High^Opt")).Any())
{
curstructset.RemoveStructure(curstructset.Structures.Where(x => x.Id.Contains("zPTV_High^Opt")).First());
}
Structure zptvhighopt = curstructset.AddStructure("ORGAN", "zPTV_High^Opt");
//Dose limiting annulus (DLA) structure is used to make the prescribed dose conformal. DLA for PTV_High is named zDLA_High
if (curstructset.Structures.Where(x => x.Id.Contains("zDLA__High")).Any())
{
curstructset.RemoveStructure(curstructset.Structures.Where(x => x.Id.Contains("zDLA__High")).First());
}
Structure zdlahigh = curstructset.AddStructure("ORGAN", "zDLA__High");
//Make zPTV_High^Opt from PTV_High and boolean out the rectum
zptvhighopt.SegmentVolume = ptv_high.Margin(0.0f);
zptvhighopt.SegmentVolume = zptvhighopt.Sub(curstructset.Structures.Where(x => x.Id.Contains("Rectum")).Single());//Boolean the Rectum out of the high dose ptv optimization structure
//Make zPTV_Low^Opt from PTV_Low and boolean out the PTV_High structure
zptvlowopt.SegmentVolume = ptv_low.Margin(0.0f);
zptvlowopt.SegmentVolume = zptvlowopt.Sub(ptv_high.Margin(1.0f));//Boolean the ptv_high out of ptv_low optimization structure
//Make a dose limiting annulus arround the low dose ptv optimization structure
zdlalow.SegmentVolume = zptvlowopt.SegmentVolume;
zdlalow.SegmentVolume = zdlalow.Margin(10.0f);
zdlalow.SegmentVolume = zdlalow.Sub(zptvlowopt.Margin(1.0f));
zdlalow.SegmentVolume = zdlalow.Sub(zptvhighopt.Margin(5.0f));
//Make a dose limiting annulus arround the high dose ptv optimization structure
zdlahigh.SegmentVolume = zptvhighopt.SegmentVolume;
zdlahigh.SegmentVolume = zdlahigh.Margin(10.0f);
zdlahigh.SegmentVolume = zdlahigh.Sub(zptvhighopt.Margin(1.0f));
sb = new StringBuilder();
sb.AppendLine("Done with creating optimization strutures");
sb.AppendLine("Click OK to proceed with setting up course and VMAT plan");
System.Windows.MessageBox.Show(sb.ToString());
//Add course
Course curcourse;
if (curpat.Courses.Where(x => x.Id == "AutoPlan").Any())
{
curcourse = curpat.Courses.Where(x => x.Id == "AutoPlan").Single();
}
else
{
curcourse = curpat.AddCourse();
curcourse.Id = "AutoPlan";
}
//Remove PlanSetup if it exists then create new plan setup
if (curcourse.PlanSetups.Where(x => x.Id == "AutoPlanVMAT").Any())
{
curcourse.RemovePlanSetup(curcourse.PlanSetups.Where(x => x.Id == "AutoPlanVMAT").Single());
}
ExternalPlanSetup cureps = curcourse.AddExternalPlanSetup(curstructset);
cureps.Id = "AutoPlanVMAT";
//Add VMAT Beams
VVector isocenter = new VVector(Math.Round(ptv_high.CenterPoint.x / 10.0f) * 10.0f, Math.Round(ptv_high.CenterPoint.y / 10.0f) * 10.0f, Math.Round(ptv_high.CenterPoint.z / 10.0f) * 10.0f);
ExternalBeamMachineParameters ebmp = new ExternalBeamMachineParameters("Truebeam", "6X", 600, "ARC", null);
Beam VMAT1 = cureps.AddArcBeam(ebmp, new VRect <double>(-100, -100, 100, 100), 30, 181, 179, GantryDirection.Clockwise, 0, isocenter);
Beam VMAT2 = cureps.AddArcBeam(ebmp, new VRect <double>(-100, -100, 100, 100), 330, 179, 181, GantryDirection.CounterClockwise, 0, isocenter);
VMAT1.Id = "CW";
VMAT2.Id = "CCW";
VMAT1.FitCollimatorToStructure(new FitToStructureMargins(10), ptv_low, true, true, false);
VMAT2.FitCollimatorToStructure(new FitToStructureMargins(10), ptv_low, true, true, false);
cureps.SetCalculationModel(CalculationType.PhotonVMATOptimization, "PO_15014");
cureps.SetPrescription(NFractions, new DoseValue(RxDose / NFractions, "Gy"), 1);
curapp.SaveModifications();
sb = new StringBuilder();
sb.AppendLine("Done with setting up course and VMAT plan");
sb.AppendLine("Click OK to proceed with plan optimization");
System.Windows.MessageBox.Show(sb.ToString());
float doseobjectivevalue_low = TargetStructures.Where(x => x.Item1 == "PTV_Low").Select(x => x.Item3).First();
float doseobjectivevalue_high = TargetStructures.Where(x => x.Item1 == "PTV_High").Select(x => x.Item3).First();
cureps.OptimizationSetup.AddPointObjective(zptvlowopt, OptimizationObjectiveOperator.Lower, new DoseValue(doseobjectivevalue_low, "Gy"), 100, 100);
cureps.OptimizationSetup.AddPointObjective(zptvlowopt, OptimizationObjectiveOperator.Upper, new DoseValue(doseobjectivevalue_low + 3.0f, "Gy"), 30, 50);
cureps.OptimizationSetup.AddPointObjective(zdlalow, OptimizationObjectiveOperator.Upper, new DoseValue(doseobjectivevalue_low, "Gy"), 0, 50);
cureps.OptimizationSetup.AddPointObjective(zptvhighopt, OptimizationObjectiveOperator.Lower, new DoseValue(doseobjectivevalue_high, "Gy"), 100, 120);
cureps.OptimizationSetup.AddPointObjective(zptvhighopt, OptimizationObjectiveOperator.Upper, new DoseValue(doseobjectivevalue_high + 2.0f, "Gy"), 0, 100);
cureps.OptimizationSetup.AddPointObjective(zdlahigh, OptimizationObjectiveOperator.Upper, new DoseValue(doseobjectivevalue_high, "Gy"), 0, 50);
cureps.OptimizationSetup.AddNormalTissueObjective(80.0f, 0.0f, 100.0f, 40.0f, 0.05f);
OptimizerResult optresult = cureps.OptimizeVMAT(new OptimizationOptionsVMAT(OptimizationIntermediateDoseOption.NoIntermediateDose, string.Empty));
sb = new StringBuilder();
sb.AppendLine("VMAT optimization is done");
sb.AppendLine("NIterattions:" + optresult.NumberOfIMRTOptimizerIterations.ToString() + " , ObjectiveFunctionValue: " + optresult.TotalObjectiveFunctionValue.ToString());
sb.AppendLine("Click OK to proceed with optimization");
cureps.OptimizeVMAT();
curapp.SaveModifications();
sb = new StringBuilder();
sb.AppendLine("Done with optimization");
sb.AppendLine("Click OK to proceed with dose calculation");
System.Windows.MessageBox.Show(sb.ToString());
cureps.CalculateDose();
//cureps.PlanNormalizationValue = 99.0f;
curapp.SaveModifications();
sb = new StringBuilder();
sb.AppendLine("Done with dose calculation");
if (cureps.StructureSet.Structures.Where(x => x.Id == "Rectum").Any())
{
Structure reportstructure = cureps.StructureSet.Structures.Where(x => x.Id == "Rectum").First();
sb.AppendLine("Rectum:V65Gy[%]:" + cureps.GetVolumeAtDose(reportstructure, new DoseValue(65.0f, DoseValue.DoseUnit.Gy), VolumePresentation.Relative).ToString());
}
sb.AppendLine("PTV_High:D95%[Gy]:" + cureps.GetDoseAtVolume(ptv_high, 95.0f, VolumePresentation.Relative, DoseValuePresentation.Absolute).ToString());
sb.AppendLine("Click OK to finish script");
System.Windows.MessageBox.Show(sb.ToString());
}
