/// <summary>
/// constructor
/// </summary>
public Consequences(VariantEffect variantEffect)
{
_variantEffect = variantEffect;
_consequences = new List <ConsequenceType>();
_consequenceDescriptors = new Dictionary <ConsequenceType, string>
{
[ConsequenceType.CodingSequenceVariant] = CodingSequenceVariantKey,
[ConsequenceType.CopyNumberIncrease] = CopyNumberIncreaseKey,
[ConsequenceType.CopyNumberDecrease] = CopyNumberDecreaseKey,
[ConsequenceType.CopyNumberChange] = CopyNumberChangeKey,
[ConsequenceType.DownstreamGeneVariant] = DownstreamGeneVariantKey,
[ConsequenceType.FeatureElongation] = FeatureElongationKey,
[ConsequenceType.FeatureTruncation] = FeatureTruncationKey,
[ConsequenceType.FivePrimeUtrVariant] = FivePrimeUtrVariantKey,
[ConsequenceType.FrameshiftVariant] = FrameshiftVariantKey,
[ConsequenceType.IncompleteTerminalCodonVariant] = IncompleteTerminalCodonVariantKey,
[ConsequenceType.InframeDeletion] = InframeDeletionKey,
[ConsequenceType.InframeInsertion] = InframeInsertionKey,
[ConsequenceType.StartLost] = StartLostKey,
[ConsequenceType.IntronVariant] = IntronVariantKey,
[ConsequenceType.MissenseVariant] = MissenseVariantKey,
[ConsequenceType.MatureMirnaVariant] = MatureMirnaVariantKey,
[ConsequenceType.NonCodingTranscriptExonVariant] = NonCodingExonVariantKey,
[ConsequenceType.NonCodingTranscriptVariant] = NonCodingTranscriptVariantKey,
[ConsequenceType.NonsenseMediatedDecayTranscriptVariant] = NonsenseMediatedDecayTranscriptVariantKey,
[ConsequenceType.ProteinAlteringVariant] = ProteinAlteringVariantKey,
[ConsequenceType.RegulatoryRegionAblation] = RegulatoryRegionAblationVariantKey,
[ConsequenceType.RegulatoryRegionAmplification] = RegulatoryRegionAmplificationVariantKey,
[ConsequenceType.RegulatoryRegionVariant] = RegulatoryRegionVariantKey,
[ConsequenceType.SpliceAcceptorVariant] = SpliceAcceptorVariantKey,
[ConsequenceType.SpliceDonorVariant] = SpliceDonorVariantKey,
[ConsequenceType.SpliceRegionVariant] = SpliceRegionVariantKey,
[ConsequenceType.StopGained] = StopGainedKey,
[ConsequenceType.StopLost] = StopLostKey,
[ConsequenceType.StopRetainedVariant] = StopRetainedVariantKey,
[ConsequenceType.SynonymousVariant] = SynonymousVariantKey,
[ConsequenceType.ThreePrimeUtrVariant] = ThreePrimeUtrVariantKey,
[ConsequenceType.TranscriptAmplification] = TranscriptAmplificationKey,
[ConsequenceType.TranscriptTruncation] = TranscriptTruncationKey,
[ConsequenceType.TranscriptAblation] = TranscriptAblatioinKey,
[ConsequenceType.Unknown] = UnknownKey,
[ConsequenceType.UpstreamGeneVariant] = UpstreamGeneVariantKey,
[ConsequenceType.TranscriptVariant] = TranscriptVariantKey,
[ConsequenceType.GeneFusion] = GeneFusionKey,
[ConsequenceType.UnidirectionalGeneFusion] = UnidirectionalGeneFusionKey,
[ConsequenceType.BidirectionalGeneFusion] = BidirectionalGeneFusionKey
};
}
public Consequences(List <ConsequenceType> consequences, VariantEffect variantEffect) : this(variantEffect)
{
_consequences.AddRange(consequences);
}