public IEnumerable<PatientProcedure> GetPatientProcedures(Fixture fixture, Random randomizer, PatientDemographics demographic, int maxNumberOfPatientProcedures)
{
fixture.Customize<PatientProcedure>(pp => pp.With(x => x.PatientId, demographic.PatientId)
.Without(x => x.CptHcpcs));
var procedures = fixture.CreateMany<PatientProcedure>(randomizer.Next(0, maxNumberOfPatientProcedures + 1)).ToList();
foreach (var procedure in procedures)
{
procedure.ProcedureDate = procedure.ProcedureDate.Date;
var hasFavoredProcedure = randomizer.NextPercent() <= ChanceOfHavingFavoredProcedure;
procedure.CptHcpcs = hasFavoredProcedure ? randomizer.NextListElement(_favoredProcedureCodes) : GetRandomProcedure(randomizer);
var isProcedureRecent = randomizer.NextPercent() <= ChanceOfHavingRecentProcedure;
if(isProcedureRecent)
{
var oldestRecentDateTime = DateTime.Today.AddMonths(-6);
if(procedure.ProcedureDate < oldestRecentDateTime)
{
var maximumNumberOfDaysForRecent = (int)(DateTime.Today - oldestRecentDateTime).TotalDays;
var daysAgo = randomizer.Next(1, maximumNumberOfDaysForRecent);
procedure.ProcedureDate = DateTime.Today.AddDays(-daysAgo);
}
}
}
return procedures.OrderBy(x => x.ProcedureDate);
}
public IEnumerable<PatientTherapy> GetPatientTherapies(Fixture fixture, Random randomizer, PatientDemographics demographic, int maxNumberOfPatientTherapies)
{
fixture.Customize<PatientTherapy>(pt => pt.With(x => x.PatientId, demographic.PatientId)
.Without(x => x.DDID)
.Without(x => x.RXNorm)
.Without(x => x.StopDate));
var therapies = fixture.CreateMany<PatientTherapy>(randomizer.Next(0, maxNumberOfPatientTherapies + 1));
foreach (var therapy in therapies)
{
var daysOnTherapy = randomizer.Next(1, 365);
therapy.StopDate = new DateTime(Math.Min(therapy.StartDate.AddDays(daysOnTherapy).Ticks, DateTime.Now.Ticks));
var hasFavoredTherapy = randomizer.NextPercent() <= ChanceOfHavingFavoredCondition;
if (hasFavoredTherapy)
{
var pair = randomizer.NextDictionaryPair(_favoredTherapies);
therapy.NDC = pair.Key;
therapy.DrugName = pair.Value;
}
else
{
therapy.NDC = NDCGenerator.GetRandomNDC(randomizer);
}
}
return therapies.OrderBy(x => x.StartDate);
}
public IEnumerable<PatientDiagnosis> GetPatientDiagnoses(Fixture fixture, Random randomizer, PatientDemographics demographic, int maxNumberOfPatientDiagnoses)
{
fixture.Customize<PatientDiagnosis>(pd => pd.With(x => x.PatientId, demographic.PatientId)
.Without(x => x.DiagnosisDescription)
.Without(x => x.ICD9)
.Without(x => x.ICD10));
var diagnoses = fixture.CreateMany<PatientDiagnosis>(randomizer.Next(0, maxNumberOfPatientDiagnoses + 1)).ToList();
foreach (var diagnosis in diagnoses)
{
var hasFavoredDiagnosis = randomizer.NextPercent() <= ChanceOfHavingFavoredDiagnosis;
var entry = hasFavoredDiagnosis ? GetSubsetEntry(randomizer, _favoredDiagnosisCodes) : randomizer.NextListElement(_icd9Entries);
DecoratePatientDiagnosisFromICD9Entry(diagnosis, entry);
}
var hasInclusionDiagnosis = randomizer.NextPercent() <= ChanceOfHavingInclusionDiagnosis;
if (hasInclusionDiagnosis)
{
var entry = GetSubsetEntry(randomizer, _inclusionDiagnosisCodes);
if (entry != null)
{
var diagnosis = fixture.Create<PatientDiagnosis>();
DecoratePatientDiagnosisFromICD9Entry(diagnosis, entry);
diagnoses.Add(diagnosis);
}
}
var hasExclusionDiagnosis = randomizer.NextPercent() <= ChanceOfHavingExclusionDiagnosis;
if (hasExclusionDiagnosis)
{
var entry = GetSubsetEntry(randomizer, _exclusionDiagnosisCodes);
if (entry != null)
{
var diagnosis = fixture.Create<PatientDiagnosis>();
DecoratePatientDiagnosisFromICD9Entry(diagnosis, entry);
diagnoses.Add(diagnosis);
}
}
return diagnoses.OrderBy(x => x.DiagnosisDate);
}
public IEnumerable<PatientLab> GetPatientLabs(Fixture fixture, Random randomizer, PatientDemographics demographic, int maxNumberOfPatientLabs)
{
fixture.Customize<PatientLab>(pl => pl.With(x => x.PatientId, demographic.PatientId));
var labs = fixture.CreateMany<PatientLab>(randomizer.Next(0, maxNumberOfPatientLabs + 1)).OrderBy(x => x.LabDate);
foreach (var lab in labs)
{
var hasFavoredLab = randomizer.NextPercent() <= ChanceOfHavingFavoredLab;
if (hasFavoredLab)
{
var pair = randomizer.NextDictionaryPair(_favoredLabs);
lab.LabName = pair.Key.Replace("[NORMAL]", string.Empty).Replace("[ABNORMAL]", string.Empty);
lab.Value = pair.Value.Invoke(randomizer);
}
}
return labs;
}
public double GetBMI(Random randomizer, bool obese = false, double? baseBMI = null)
{
var minimumBMI = obese ? MinimumObeseBMI : MinimumNormalBMI;
var maximumBMI = obese ? MaximumObeseBMI : MaximumNormalBMI;
var bmi = baseBMI ?? randomizer.Next(minimumBMI, maximumBMI + 1);
if (baseBMI.HasValue)
{
var hasBMIChanged = randomizer.NextPercent() <= ChanceOfBMIChange;
if (hasBMIChanged)
{
var direction = randomizer.NextDouble() > 0.5 ? 1 : -1;
var delta = randomizer.Next(0, MaximumDelta + 1) * direction;
bmi += delta;
}
}
return Math.Max(Math.Min(bmi, maximumBMI), minimumBMI);
}
static void Main(string[] args)
{
var randomizer = new Random((int)DateTime.Now.Ticks);
var allClaimsTherapies = new List<ClaimsTherapy>();
var allClaimsUtilizations = new List<ClaimsUtilization>();
var allPatientAllergies = new List<PatientAllergy>();
var allPatientClinicals = new List<PatientClinical>();
var allPatientDemographics = new List<PatientDemographics>();
var allPatientDiagnoses = new List<PatientDiagnosis>();
var allPatientLabs = new List<PatientLab>();
var allPatientProcedures = new List<PatientProcedure>();
var allPatientTherapies = new List<PatientTherapy>();
var allPatientUtilizations = new List<PatientUtilization>();
var fixture = new Fixture();
fixture.Customizations.Add(new PatientSpecimenBuilder());
int maxNumberOfClaimsTherapies = 5;
int maxNumberOfClaimsUtilizations = 10;
int maxNumberOfPatientAllergies = 5;
int maxNumberOfPatientClinicals = 10;
int maxNumberOfPatientDiagnoses = 10;
int maxNumberOfPatientLabs = 20;
int maxNumberOfPatientProcedures = 5;
int maxNumberOfPatientTherapies = 20;
int maxNumberOfPatientUtilizations = 15;
int numberOfPatients = 50;
for (int i = 0; i < numberOfPatients; i++)
{
var alcoholAbuse = fixture.Create<bool>();
var drugAbuse = fixture.Create<bool>();
var smoker = fixture.Create<bool>();
var chanceOfObesity = 15;
var obese = randomizer.NextPercent() < chanceOfObesity;
var demographic = PatientDemographicBuilder.Instance.GetPatientDemographic(randomizer);
var clinicals = PatientClinicalBuilder.Instance.GetPatientClinicals(fixture, randomizer, demographic, alcoholAbuse, drugAbuse, smoker, obese, maxNumberOfPatientClinicals);
var utilizations = PatientUtilizationBuilder.Instance.GetPatientUtilizations(fixture, randomizer, demographic, maxNumberOfPatientUtilizations);
var diagnoses = PatientDiagnosisBuilder.Instance.GetPatientDiagnoses(fixture, randomizer, demographic, maxNumberOfPatientDiagnoses);
var labs = PatientLabBuilder.Instance.GetPatientLabs(fixture, randomizer, demographic, maxNumberOfPatientLabs);
var therapies = PatientTherapyBuilder.Instance.GetPatientTherapies(fixture, randomizer, demographic, maxNumberOfPatientTherapies);
var allergies = PatientAllergyBuilder.Instance.GetPatientAllergies(fixture, randomizer, demographic, maxNumberOfPatientAllergies);
var procedures = PatientProcedureBuilder.Instance.GetPatientProcedures(fixture, randomizer, demographic, maxNumberOfPatientProcedures);
var claimsUtilizations = ClaimsUtilizationBuilder.Instance.GetClaimsUtilizations(fixture, randomizer, demographic, alcoholAbuse, drugAbuse, maxNumberOfClaimsUtilizations);
var claimsTherapies = ClaimsTherapyBuilder.Instance.GetClaimsTherapies(fixture, randomizer, demographic, alcoholAbuse, drugAbuse, maxNumberOfClaimsTherapies);
allClaimsTherapies.AddRange(claimsTherapies);
allClaimsUtilizations.AddRange(claimsUtilizations);
allPatientAllergies.AddRange(allergies);
allPatientClinicals.AddRange(clinicals);
allPatientDemographics.Add(demographic);
allPatientDiagnoses.AddRange(diagnoses);
allPatientLabs.AddRange(labs);
allPatientProcedures.AddRange(procedures);
allPatientTherapies.AddRange(therapies);
allPatientUtilizations.AddRange(utilizations);
}
string FOLDERPATH = "c:\\temp";
string timestamp = DateTime.Now.ToString("yyyyMMddHHmmss");
var writer = new CsvWriter();
writer.WriteToFile($"{FOLDERPATH}\\{timestamp}.unofficial.patientdemographics.csv", allPatientDemographics);
writer.WriteToFile($"{FOLDERPATH}\\{timestamp}.unofficial.patientclinicals.csv", allPatientClinicals);
writer.WriteToFile($"{FOLDERPATH}\\{timestamp}.unofficial.patientutilizations.csv", allPatientUtilizations);
writer.WriteToFile($"{FOLDERPATH}\\{timestamp}.unofficial.patientdiagnoses.csv", allPatientDiagnoses);
writer.WriteToFile($"{FOLDERPATH}\\{timestamp}.unofficial.patientlabs.csv", allPatientLabs);
writer.WriteToFile($"{FOLDERPATH}\\{timestamp}.unofficial.patienttherapies.csv", allPatientTherapies);
writer.WriteToFile($"{FOLDERPATH}\\{timestamp}.unofficial.patientallergies.csv", allPatientAllergies);
writer.WriteToFile($"{FOLDERPATH}\\{timestamp}.unofficial.patientprocedures.csv", allPatientProcedures);
writer.WriteToFile($"{FOLDERPATH}\\{timestamp}.unofficial.claimstherapies.csv", allClaimsTherapies);
writer.WriteToFile($"{FOLDERPATH}\\{timestamp}.unofficial.claimsutilizations.csv", allClaimsUtilizations);
}