Exemplo n.º 1
0
		///<summary>This is the first step of automation, this checks to see if the new object matches one of the trigger conditions. </summary>
		/// <param name="triggerObject">Can be DiseaseDef, ICD9, Icd10, Snomed, Medication, RxNorm, Cvx, AllerfyDef, EHRLabResult, Patient, or VitalSign.</param>
		/// <param name="PatCur">Triggers and intervention are currently always dependant on current patient. </param>
		/// <returns>Returns a dictionary keyed on triggers and a list of all the objects that the trigger matched on. Should be used to generate CDS intervention message and later be passed to FormInfobutton for knowledge request.</returns>
		public static List<CDSIntervention> TriggerMatch(object triggerObject,Patient PatCur) {
			if(RemotingClient.RemotingRole==RemotingRole.ClientWeb) {
				return Meth.GetObject<List<CDSIntervention>>(MethodBase.GetCurrentMethod(),triggerObject,PatCur);
			}
			//Dictionary<string,List<object>> retVal=new Dictionary<string,List<object>>();
			List<CDSIntervention> retVal=new List<CDSIntervention>();
			//Define objects to be used in matching triggers.
			DiseaseDef diseaseDef;
			ICD9 icd9;
			Icd10 icd10;
			Snomed snomed;
			Medication medication;
			RxNorm rxNorm;
			Cvx cvx;
			AllergyDef allergyDef;
			EhrLabResult ehrLabResult;
			Patient pat;
			Vitalsign vitalsign;
			string triggerObjectMessage="";
			string command="";
			switch(triggerObject.GetType().Name) {
				case "DiseaseDef":
					diseaseDef=(DiseaseDef)triggerObject;
					command="SELECT * FROM ehrtrigger"
					+" WHERE ProblemDefNumList LIKE '% "+POut.String(diseaseDef.DiseaseDefNum.ToString())+" %'";// '% <code> %' so that we can get exact matches.
					if(diseaseDef.ICD9Code!="") {
						command+=" OR ProblemIcd9List LIKE '% "+POut.String(diseaseDef.ICD9Code)+" %'";
						ICD9 icd10Cur=ICD9s.GetByCode(diseaseDef.ICD9Code);
						if(icd10Cur!=null){
							triggerObjectMessage+="  -"+diseaseDef.ICD9Code+"(Icd9)  "+icd10Cur.Description+"\r\n";
						}
					}
					if(diseaseDef.Icd10Code!="") {
						command+=" OR ProblemIcd10List LIKE '% "+POut.String(diseaseDef.Icd10Code)+" %'";
						Icd10 icd10Cur=Icd10s.GetByCode(diseaseDef.Icd10Code);
						if(icd10Cur!=null) {
							triggerObjectMessage+="  -"+diseaseDef.Icd10Code+"(Icd10)  "+icd10Cur.Description+"\r\n";
						}
					}
					if(diseaseDef.SnomedCode!="") {
						command+=" OR ProblemSnomedList LIKE '% "+POut.String(diseaseDef.SnomedCode)+" %'";
						Snomed snomedCur=Snomeds.GetByCode(diseaseDef.SnomedCode);
						if(snomedCur!=null) {
							triggerObjectMessage+="  -"+diseaseDef.SnomedCode+"(Snomed)  "+snomedCur.Description+"\r\n";
						}
					}
					break;
				case "ICD9":
					icd9=(ICD9)triggerObject;
					//TODO: TriggerObjectMessage
					command="SELECT * FROM ehrtrigger"
					+" WHERE Icd9List LIKE '% "+POut.String(icd9.ICD9Code)+" %'";// '% <code> %' so that we can get exact matches.
					break;
				case "Icd10":
					icd10=(Icd10)triggerObject;
					//TODO: TriggerObjectMessage
					command="SELECT * FROM ehrtrigger"
					+" WHERE Icd10List LIKE '% "+POut.String(icd10.Icd10Code)+" %'";// '% <code> %' so that we can get exact matches.
					break;
				case "Snomed":
					snomed=(Snomed)triggerObject;
					//TODO: TriggerObjectMessage
					command="SELECT * FROM ehrtrigger"
					+" WHERE SnomedList LIKE '% "+POut.String(snomed.SnomedCode)+" %'";// '% <code> %' so that we can get exact matches.
					break;
				case "Medication":
					medication=(Medication)triggerObject;
					RxNorm rxNormCur=RxNorms.GetByRxCUI(medication.RxCui.ToString());
					if(rxNormCur!=null) {
						triggerObjectMessage="  - "+medication.MedName+(medication.RxCui==0?"":" (RxCui:"+rxNormCur.RxCui+")")+"\r\n";
					}
					command="SELECT * FROM ehrtrigger"
					+" WHERE MedicationNumList LIKE '% "+POut.String(medication.MedicationNum.ToString())+" %'";// '% <code> %' so that we can get exact matches.
					if(medication.RxCui!=0) {
						command+=" OR RxCuiList LIKE '% "+POut.String(medication.RxCui.ToString())+" %'";// '% <code> %' so that we can get exact matches.
					}
					break;
				case "RxNorm":
					rxNorm=(RxNorm)triggerObject;
					triggerObjectMessage="  - "+rxNorm.Description+"(RxCui:"+rxNorm.RxCui+")\r\n";
					command="SELECT * FROM ehrtrigger"
					+" WHERE RxCuiList LIKE '% "+POut.String(rxNorm.RxCui)+" %'";// '% <code> %' so that we can get exact matches.
					break;
				case "Cvx":
					cvx=(Cvx)triggerObject;
					//TODO: TriggerObjectMessage
					command="SELECT * FROM ehrtrigger"
					+" WHERE CvxList LIKE '% "+POut.String(cvx.CvxCode)+" %'";// '% <code> %' so that we can get exact matches.
					break;
				case "AllergyDef":
					allergyDef=(AllergyDef)triggerObject;
					//TODO: TriggerObjectMessage
					command="SELECT * FROM ehrtrigger"
					+" WHERE AllergyDefNumList LIKE '% "+POut.String(allergyDef.AllergyDefNum.ToString())+" %'";// '% <code> %' so that we can get exact matches.
					break;
				case "EhrLabResult"://match loinc only, no longer 
					ehrLabResult=(EhrLabResult)triggerObject;
					//TODO: TriggerObjectMessage
					command="SELECT * FROM ehrtrigger WHERE "
						+"(LabLoincList LIKE '% "+ehrLabResult.ObservationIdentifierID+" %'" //LOINC may be in one of two fields
						+"OR LabLoincList LIKE '% "+ehrLabResult.ObservationIdentifierIDAlt+" %')"; //LOINC may be in one of two fields
					break;
				case "Patient":
					pat=(Patient)triggerObject;
					List<string> triggerNums=new List<string>();
					//TODO: TriggerObjectMessage
					command="SELECT * FROM ehrtrigger WHERE DemographicsList !=''";
					List<EhrTrigger> triggers=Crud.EhrTriggerCrud.SelectMany(command);
					for(int i=0;i<triggers.Count;i++) {
						string[] arrayDemoItems=triggers[i].DemographicsList.Split(new string[] { " " },StringSplitOptions.RemoveEmptyEntries);
						for(int j=0;j<arrayDemoItems.Length;j++) {
							switch(arrayDemoItems[j].Split(',')[0]) {
								case "age":
									int val=PIn.Int(Regex.Match(arrayDemoItems[j],@"\d+").Value);
									if(arrayDemoItems[j].Contains("=")) {//=, >=, or <=
										if(val==pat.Age) {
											triggerNums.Add(triggers[i].EhrTriggerNum.ToString());
											break;
										}
									}
									if(arrayDemoItems[j].Contains("<")){
										if(pat.Age<val){
											triggerNums.Add(triggers[i].EhrTriggerNum.ToString());
											break;
										}
									}
									if(arrayDemoItems[j].Contains(">")) {
										if(pat.Age>val) {
											triggerNums.Add(triggers[i].EhrTriggerNum.ToString());
											break;
										}
									}
									//should never happen, age element didn't contain a comparator
										break;
								case "gender":
										if(arrayDemoItems[j].Split(',')[0].StartsWith(pat.Gender.ToString())) {
											triggerNums.Add(triggers[i].EhrTriggerNum.ToString());
										}
									break;
								default:
									break;//should never happen
							}
						}
					}
					triggerNums.Add("-1");//to ensure the querry is valid.
					command="SELECT * FROM ehrTrigger WHERE EhrTriggerNum IN ("+String.Join(",",triggerNums)+")";
					break;
				case "Vitalsign":
					List<string> trigNums=new List<string>();
					vitalsign=(Vitalsign)triggerObject;
					command="SELECT * FROM ehrtrigger WHERE VitalLoincList !=''";
					List<EhrTrigger> triggersVit=Crud.EhrTriggerCrud.SelectMany(command);
					for(int i=0;i<triggersVit.Count;i++) {
						string[] arrayVitalItems=triggersVit[i].VitalLoincList.Split(new string[] { " " },StringSplitOptions.RemoveEmptyEntries);
						for(int j=0;j<arrayVitalItems.Length;j++) {
							double val=PIn.Double(Regex.Match(arrayVitalItems[j],@"\d+(.(\d+))*").Value);//decimal value w or w/o decimal.
							switch(arrayVitalItems[j].Split(',')[0]) {
								case "height":
									if(arrayVitalItems[j].Contains("=")) {//=, >=, or <=
										if(vitalsign.Height==val) {
											trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
											break;
										}
									}
									if(arrayVitalItems[j].Contains("<")) {
										if(vitalsign.Height<val) {
											trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
											break;
										}
									}
									if(arrayVitalItems[j].Contains(">")) {
										if(vitalsign.Height>val) {
											trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
											break;
										}
									}
									//should never happen, Height element didn't contain a comparator
									break;
								case "weight":
									if(arrayVitalItems[j].Contains("=")) {//=, >=, or <=
										if(vitalsign.Weight==val) {
											trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
											break;
										}
									}
									if(arrayVitalItems[j].Contains("<")) {
										if(vitalsign.Weight<val) {
											trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
											break;
										}
									}
									if(arrayVitalItems[j].Contains(">")) {
										if(vitalsign.Weight>val) {
											trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
											break;
										}
									}
									break;
								case "BMI":
									float BMI=Vitalsigns.CalcBMI(vitalsign.Weight,vitalsign.Height);
									if(arrayVitalItems[j].Contains("=")) {//=, >=, or <=
										if(BMI==val) {
											trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
											break;
										}
									}
									if(arrayVitalItems[j].Contains("<")) {
										if(BMI<val) {
											trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
											break;
										}
									}
									if(arrayVitalItems[j].Contains(">")) {
										if(BMI>val) {
											trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
											break;
										}
									}
									break;
								case "BP":
									//TODO
									break;
							}//end switch
						}
					}//End Triggers Vit
					trigNums.Add("-1");//to ensure the querry is valid.
					command="SELECT * FROM ehrTrigger WHERE EhrTriggerNum IN ("+String.Join(",",trigNums)+")";
					break;
				default:
					//command="SELECT * FROM ehrtrigger WHERE false";//should not return any results.
					return null;
					#if DEBUG
						throw new Exception(triggerObject.GetType().ToString()+" object not implemented as intervention trigger yet. Add to the list above to handle.");
					#endif
					//break;
			}
			List<EhrTrigger> listEhrTriggers=Crud.EhrTriggerCrud.SelectMany(command);
			if(listEhrTriggers.Count==0){
				return null;//no triggers matched.
			}
			//Check for MatchCardinality.One type triggers.----------------------------------------------------------------------------
			for(int i=0;i<listEhrTriggers.Count;i++) {
				if(listEhrTriggers[i].Cardinality!=MatchCardinality.One) {
					continue;
				}
				string triggerMessage=listEhrTriggers[i].Description+":\r\n";//Example:"Patient over 55:\r\n"
				triggerMessage+=triggerObjectMessage;//Example:"  -Patient Age 67\r\n"
				List<object> ListObjectMatches=new List<object>();
				ListObjectMatches.Add(triggerObject);
				CDSIntervention cdsi=new CDSIntervention();
				cdsi.EhrTrigger=listEhrTriggers[i];
				cdsi.InterventionMessage=triggerMessage;
				cdsi.TriggerObjects=ListObjectMatches;
				retVal.Add(cdsi);
			}
			//Fill object lists to be checked-------------------------------------------------------------------------------------------------
			List<Allergy> ListAllergy=Allergies.GetAll(PatCur.PatNum,false);
			List<Disease> ListDisease=Diseases.Refresh(PatCur.PatNum,true);
			List<DiseaseDef> ListDiseaseDef=new List<DiseaseDef>();
			List<EhrLab> ListEhrLab=EhrLabs.GetAllForPat(PatCur.PatNum);
			//List<EhrLabResult> ListEhrLabResults=null;//Lab results are stored in a list in the EhrLab object.
			List<MedicationPat> ListMedicationPat=MedicationPats.Refresh(PatCur.PatNum,false);
			List<AllergyDef> ListAllergyDef=new List<AllergyDef>();
			for(int i=0;i<ListAllergy.Count;i++){
				ListAllergyDef.Add(AllergyDefs.GetOne(ListAllergy[i].AllergyDefNum));
			}
			for(int i=0;i<ListDisease.Count;i++){
				ListDiseaseDef.Add(DiseaseDefs.GetItem(ListDisease[i].DiseaseDefNum));
			}
			for(int i=0;i<listEhrTriggers.Count;i++) {
				if(listEhrTriggers[i].Cardinality==MatchCardinality.One) {
					continue;//we handled these above.
				}
				string triggerMessage=listEhrTriggers[i].Description+":\r\n";
				triggerMessage+=triggerObjectMessage;
				List<object> ListObjectMatches=new List<object>();//Allergy, Disease, LabPanels, MedicationPat, Patient, VaccinePat
				ListObjectMatches.Add(triggerObject);
				//Allergy-----------------------------------------------------------------------------------------------------------------------
				//allergy.snomedreaction
				//allergy.AllergyDefNum>>AllergyDef.SnomedType
				//allergy.AllergyDefNum>>AllergyDef.SnomedAllergyTo
				//allergy.AllergyDefNum>>AllergyDef.MedicationNum>>Medication.RxCui
				//Disease-----------------------------------------------------------------------------------------------------------------------
				//Disease.DiseaseDefNum>>DiseaseDef.ICD9Code
				//Disease.DiseaseDefNum>>DiseaseDef.SnomedCode
				//Disease.DiseaseDefNum>>DiseaseDef.Icd10Code
				//LabPanels---------------------------------------------------------------------------------------------------------------------
				//LabPanel.LabPanelNum<<LabResult.TestId (Loinc)
				//LabPanel.LabPanelNum<<LabResult.ObsValue (Loinc)
				//LabPanel.LabPanelNum<<LabResult.ObsRange (Loinc)
				//MedicationPat-----------------------------------------------------------------------------------------------------------------
				//MedicationPat.RxCui
				//MedicationPat.MedicationNum>>Medication.RxCui
				//Patient>>Demographics---------------------------------------------------------------------------------------------------------
				//Patient.Gender
				//Patient.Birthdate (Loinc age?)
				//Patient.SmokingSnoMed
				//RxPat-------------------------------------------------------------------------------------------------------------------------
				//Do not check RxPat. It is useless.
				//VaccinePat--------------------------------------------------------------------------------------------------------------------
				//VaccinePat.VaccineDefNum>>VaccineDef.CVXCode
				//VitalSign---------------------------------------------------------------------------------------------------------------------
				//VitalSign.Height (Loinc)
				//VitalSign.Weight (Loinc)
				//VitalSign.BpSystolic (Loinc)
				//VitalSign.BpDiastolic (Loinc)
				//VitalSign.WeightCode (Snomed)
				//VitalSign.PregDiseaseNum (Snomed)
				//Use object matches to check if required conditions are met-------------------------------------------------------------------------------
				switch(listEhrTriggers[i].Cardinality) {
					case MatchCardinality.One:
						//should never get here, handled above.
						continue;
					case MatchCardinality.OneOfEachCategory://falls through to two or more, but then branches at the end of the case statement.
					case MatchCardinality.TwoOrMore:
						//if(ListObjectMatches.Count<2) {
						//	continue;//Must match at least two objects for this category.
						//}
						//Medication
						for(int m=0;m<ListMedicationPat.Count;m++) {
							if(listEhrTriggers[i].MedicationNumList.Contains(" "+ListMedicationPat[m].MedicationNum+" ")) {
								ListObjectMatches.Add(ListMedicationPat[m]);
								continue;
							}
							if(ListMedicationPat[m].RxCui!=0 
								&& listEhrTriggers[i].RxCuiList.Contains(" "+ListMedicationPat[m].RxCui+" ")) 
							{
								ListObjectMatches.Add(ListMedicationPat[m]);
								continue;
							}
						}
						//Allergy
						for(int a=0;a<ListAllergy.Count;a++) {
							if(listEhrTriggers[i].AllergyDefNumList.Contains(" "+ListAllergy[a].AllergyDefNum+" ")) {
								AllergyDef allergyDefCur=AllergyDefs.GetOne(ListAllergy[a].AllergyDefNum);
								if(allergyDefCur!=null) {
									ListObjectMatches.Add(allergyDefCur);
									triggerMessage+="  -(Allergy) "+allergyDefCur.Description+"\r\n";
								}
								continue;
							}
						}
						//Problem
						for(int d=0;d<ListDiseaseDef.Count;d++) {
							if(ListDiseaseDef[d].ICD9Code!=""
								&& listEhrTriggers[i].ProblemIcd9List.Contains(" "+ListDiseaseDef[d].ICD9Code+" ")) 
							{
								ICD9 currentICD9=ICD9s.GetByCode(ListDiseaseDef[d].ICD9Code);
								if(currentICD9!=null) {
									ListObjectMatches.Add(ListDiseaseDef[d]);
									triggerMessage+="  -(ICD9) "+currentICD9.Description+"\r\n";
								}
								continue;
							}
							if(ListDiseaseDef[d].Icd10Code!=""
								&& listEhrTriggers[i].ProblemIcd10List.Contains(" "+ListDiseaseDef[d].Icd10Code+" ")) {
								Icd10 icd10Cur=Icd10s.GetByCode(ListDiseaseDef[d].Icd10Code);
								if(icd10Cur!=null) {
									ListObjectMatches.Add(ListDiseaseDef[d]);
									triggerMessage+="  -(Icd10) "+icd10Cur.Description+"\r\n";
								}
								continue;
							}
							if(ListDiseaseDef[d].SnomedCode!=""
								&& listEhrTriggers[i].ProblemSnomedList.Contains(" "+ListDiseaseDef[d].SnomedCode+" ")) {
								Snomed snomedCur=Snomeds.GetByCode(ListDiseaseDef[d].SnomedCode);
								if(snomedCur!=null) {
									ListObjectMatches.Add(ListDiseaseDef[d]);
									triggerMessage+="  -(Snomed) "+snomedCur.Description+"\r\n";
								}
								continue;
							}
							if(listEhrTriggers[i].ProblemDefNumList.Contains(" "+ListDiseaseDef[d].DiseaseDefNum+" ")) {
								ListObjectMatches.Add(ListDiseaseDef[d]);
								triggerMessage+="  -(Problem Def) "+ListDiseaseDef[d].DiseaseName+"\r\n";
								continue;
							}
						}
						//Vital
						//TODO
						//Age
						//TODO
						//Gender
						//TODO
						//Lab Result
						for(int l=0;l<ListEhrLab.Count;l++) {
							for(int r=0;r<ListEhrLab[l].ListEhrLabResults.Count;r++) {
								if(listEhrTriggers[i].LabLoincList.Contains(" "+ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierID+" ")
									|| listEhrTriggers[i].LabLoincList.Contains(" "+ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierIDAlt+" ")) 
								{
									ListObjectMatches.Add(ListEhrLab[l].ListEhrLabResults[r]);
									if(ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierID!="") {//should almost always be the case.
										Loinc loincCur=Loincs.GetByCode(ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierID);
										triggerMessage+="  -(LOINC) "+loincCur.NameShort+"\r\n";
									}
									else if(ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierIDAlt!="") {
										Loinc loincCur=Loincs.GetByCode(ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierIDAlt);
										triggerMessage+="  -(LOINC) "+loincCur.NameShort+"\r\n";
									}
									else if(ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierText!="") {
										triggerMessage+="  -(LOINC) "+ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierText+"\r\n";
									}
									else if(ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierTextAlt!="") {
										triggerMessage+="  -(LOINC) "+ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierTextAlt+"\r\n";
									}
									else if(ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierID!="") {
										triggerMessage+="  -(LOINC) "+ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierID+"\r\n";
									}
									else if(ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierIDAlt!="") {
										triggerMessage+="  -(LOINC) "+ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierIDAlt+"\r\n";
									}
									else if(ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierTextOriginal!="") {
										triggerMessage+="  -(LOINC) "+ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierTextOriginal+"\r\n";
									}
									else {
										triggerMessage+="  -(LOINC) Unknown code.\r\n";//should never happen.
									}
									continue;
								}
							}
						}
						ListObjectMatches=RemoveDuplicateObjectsHelper(ListObjectMatches);
						if(listEhrTriggers[i].Cardinality==MatchCardinality.TwoOrMore && ListObjectMatches.Count<2) {
							continue;//next trigger, do not add to retVal
						}
						if(listEhrTriggers[i].Cardinality==MatchCardinality.OneOfEachCategory && !OneOfEachCategoryHelper(listEhrTriggers[i],ListObjectMatches)) {
							continue;
						}
						break;
					case MatchCardinality.All:
						bool allConditionsMet=true;
						List<string> MatchedCodes=getCodesFromListHelper(ListObjectMatches);//new List<string>();
						//Match all Icd9Codes-------------------------------------------------------------------------------------------------------------------------------------------------
						string[] arrayIcd9Codes=listEhrTriggers[i].ProblemIcd9List.Split(new string[] {" "},StringSplitOptions.RemoveEmptyEntries);
						for(int c=0;c<arrayIcd9Codes.Length;c++) {
							if(MatchedCodes.Contains(arrayIcd9Codes[i])){
								continue;//found required code
							}
							//required code not found, set allConditionsMet to false and continue to next trigger
							allConditionsMet=false;
							break;
						}
						if(!allConditionsMet) {
							continue;//next trigger
						}
						//Match all Icd10Codes------------------------------------------------------------------------------------------------------------------------------------------------
						string[] arrayIcd10Codes=listEhrTriggers[i].ProblemIcd10List.Split(new string[] {" "},StringSplitOptions.RemoveEmptyEntries);
						for(int c=0;c<arrayIcd10Codes.Length;c++) {
							if(MatchedCodes.Contains(arrayIcd10Codes[i])){
								continue;//found required code
							}
							//required code not found, set allConditionsMet to false and continue to next trigger
							allConditionsMet=false;
							break;
						}
						if(!allConditionsMet) {
							continue;//next trigger
						}
						//Match all SnomedCodes-----------------------------------------------------------------------------------------------------------------------------------------------
						string[] arraySnomedCodes=listEhrTriggers[i].ProblemSnomedList.Split(new string[] { " " },StringSplitOptions.RemoveEmptyEntries);
						for(int c=0;c<arraySnomedCodes.Length;c++) {
							if(MatchedCodes.Contains(arraySnomedCodes[i])) {
								continue;//found required code
							}
							//required code not found, set allConditionsMet to false and continue to next trigger
							allConditionsMet=false;
							break;
						}
						if(!allConditionsMet) {
							continue;//next trigger
						}
						//Match all CvxCodes--------------------------------------------------------------------------------------------------------------------------------------------------
						string[] arrayCvxCodes=listEhrTriggers[i].CvxList.Split(new string[] { " " },StringSplitOptions.RemoveEmptyEntries);
						for(int c=0;c<arrayCvxCodes.Length;c++) {
							if(MatchedCodes.Contains(arrayCvxCodes[i])) {
								continue;//found required code
							}
							//required code not found, set allConditionsMet to false and continue to next trigger
							allConditionsMet=false;
							break;
						}
						if(!allConditionsMet) {
							continue;//next trigger, do not add to retval
						}
						//Match all LoincCodes------------------------------------------------------------------------------------------------------------------------------------------------
						string[] arrayLoincCodes=listEhrTriggers[i].LabLoincList.Split(new string[] { " " },StringSplitOptions.RemoveEmptyEntries);
						for(int c=0;c<arrayLoincCodes.Length;c++) {
							if(MatchedCodes.Contains(arrayLoincCodes[i])) {
								continue;//found required code
							}
							//required code not found, set allConditionsMet to false and continue to next trigger
							allConditionsMet=false;
							break;
						}
						if(!allConditionsMet) {
							continue;//next trigger, do not add to retval
						}
						//TODO:with values
						//Match all Vitals----------------------------------------------------------------------------------------------------------------------------------------------------
						//TODO:with values
						//Match all Demographics---------------------------------------------------------------------------------------------------------------------------------------------
						//if(listEhrTriggers[i].DemographicAgeGreaterThan!=0){
						//	if(PatCur.Birthdate.Year>1880 && PatCur.Birthdate.AddYears(listEhrTriggers[i].DemographicAgeGreaterThan)>DateTime.Now){//patient too young
						//		continue;//next trigger
						//	}
						//}
						//if(listEhrTriggers[i].DemographicAgeLessThan!=0){
						//	if(PatCur.Birthdate.Year>1880 && PatCur.Birthdate.AddYears(listEhrTriggers[i].DemographicAgeGreaterThan)<DateTime.Now){//patient too old
						//		continue;//next trigger
						//	}
						//}
						//if(listEhrTriggers[i].DemographicGender!=""){
						//	if(!listEhrTriggers[i].DemographicGender.Contains(PatCur.Gender.ToString())){//Patient Gender not in gender list of trigger
						//		continue;//next trigger
						//	}
						//}
						//TODO: construct trigger message using all the codes in the trigger.
						break;
				}//end switch trigger cardinality
				//retVal.Add(triggerMessage,ListObjectMatches);
				CDSIntervention cdsi=new CDSIntervention();
				cdsi.EhrTrigger=listEhrTriggers[i];
				cdsi.InterventionMessage=triggerMessage;
				cdsi.TriggerObjects=ListObjectMatches;
				retVal.Add(cdsi);
			}//end triggers
			return retVal;
		}
Exemplo n.º 2
0
        ///<summary>This is the first step of automation, this checks to see if the new object matches one of the trigger conditions. </summary>
        /// <param name="triggerObject">Can be DiseaseDef, ICD9, Icd10, Snomed, Medication, RxNorm, Cvx, AllerfyDef, EHRLabResult, Patient, or VitalSign.</param>
        /// <param name="PatCur">Triggers and intervention are currently always dependant on current patient. </param>
        /// <returns>Returns a dictionary keyed on triggers and a list of all the objects that the trigger matched on. Should be used to generate CDS intervention message and later be passed to FormInfobutton for knowledge request.</returns>
        public static List <CDSIntervention> TriggerMatch(object triggerObject, Patient PatCur)
        {
            if (RemotingClient.RemotingRole == RemotingRole.ClientWeb)
            {
                return(Meth.GetObject <List <CDSIntervention> >(MethodBase.GetCurrentMethod(), triggerObject, PatCur));
            }
            //Dictionary<string,List<object>> retVal=new Dictionary<string,List<object>>();
            List <CDSIntervention> retVal = new List <CDSIntervention>();
            //Define objects to be used in matching triggers.
            DiseaseDef   diseaseDef;
            ICD9         icd9;
            Icd10        icd10;
            Snomed       snomed;
            Medication   medication;
            RxNorm       rxNorm;
            Cvx          cvx;
            AllergyDef   allergyDef;
            EhrLabResult ehrLabResult;
            Patient      pat;
            Vitalsign    vitalsign;
            string       triggerObjectMessage = "";
            string       command = "";

            switch (triggerObject.GetType().Name)
            {
            case "DiseaseDef":
                diseaseDef = (DiseaseDef)triggerObject;
                command    = "SELECT * FROM ehrtrigger"
                             + " WHERE ProblemDefNumList LIKE '% " + POut.String(diseaseDef.DiseaseDefNum.ToString()) + " %'";      // '% <code> %' so that we can get exact matches.
                if (diseaseDef.ICD9Code != "")
                {
                    command += " OR ProblemIcd9List LIKE '% " + POut.String(diseaseDef.ICD9Code) + " %'";
                    triggerObjectMessage += "  -" + diseaseDef.ICD9Code + "(Icd9)  " + ICD9s.GetByCode(diseaseDef.ICD9Code).Description + "\r\n";
                }
                if (diseaseDef.Icd10Code != "")
                {
                    command += " OR ProblemIcd10List LIKE '% " + POut.String(diseaseDef.Icd10Code) + " %'";
                    triggerObjectMessage += "  -" + diseaseDef.Icd10Code + "(Icd10)  " + Icd10s.GetByCode(diseaseDef.Icd10Code).Description + "\r\n";
                }
                if (diseaseDef.SnomedCode != "")
                {
                    command += " OR ProblemSnomedList LIKE '% " + POut.String(diseaseDef.SnomedCode) + " %'";
                    triggerObjectMessage += "  -" + diseaseDef.SnomedCode + "(Snomed)  " + Snomeds.GetByCode(diseaseDef.SnomedCode).Description + "\r\n";
                }
                break;

            case "ICD9":
                icd9 = (ICD9)triggerObject;
                //TODO: TriggerObjectMessage
                command = "SELECT * FROM ehrtrigger"
                          + " WHERE Icd9List LIKE '% " + POut.String(icd9.ICD9Code) + " %'";         // '% <code> %' so that we can get exact matches.
                break;

            case "Icd10":
                icd10 = (Icd10)triggerObject;
                //TODO: TriggerObjectMessage
                command = "SELECT * FROM ehrtrigger"
                          + " WHERE Icd10List LIKE '% " + POut.String(icd10.Icd10Code) + " %'";         // '% <code> %' so that we can get exact matches.
                break;

            case "Snomed":
                snomed = (Snomed)triggerObject;
                //TODO: TriggerObjectMessage
                command = "SELECT * FROM ehrtrigger"
                          + " WHERE SnomedList LIKE '% " + POut.String(snomed.SnomedCode) + " %'";         // '% <code> %' so that we can get exact matches.
                break;

            case "Medication":
                medication           = (Medication)triggerObject;
                triggerObjectMessage = "  - " + medication.MedName + (medication.RxCui == 0?"":" (RxCui:" + RxNorms.GetByRxCUI(medication.RxCui.ToString()).RxCui + ")") + "\r\n";
                command = "SELECT * FROM ehrtrigger"
                          + " WHERE MedicationNumList LIKE '% " + POut.String(medication.MedicationNum.ToString()) + " %'";         // '% <code> %' so that we can get exact matches.
                if (medication.RxCui != 0)
                {
                    command += " OR RxCuiList LIKE '% " + POut.String(medication.RxCui.ToString()) + " %'";                      // '% <code> %' so that we can get exact matches.
                }
                break;

            case "RxNorm":
                rxNorm = (RxNorm)triggerObject;
                triggerObjectMessage = "  - " + rxNorm.Description + "(RxCui:" + rxNorm.RxCui + ")\r\n";
                command = "SELECT * FROM ehrtrigger"
                          + " WHERE RxCuiList LIKE '% " + POut.String(rxNorm.RxCui) + " %'";         // '% <code> %' so that we can get exact matches.
                break;

            case "Cvx":
                cvx = (Cvx)triggerObject;
                //TODO: TriggerObjectMessage
                command = "SELECT * FROM ehrtrigger"
                          + " WHERE CvxList LIKE '% " + POut.String(cvx.CvxCode) + " %'";         // '% <code> %' so that we can get exact matches.
                break;

            case "AllergyDef":
                allergyDef = (AllergyDef)triggerObject;
                //TODO: TriggerObjectMessage
                command = "SELECT * FROM ehrtrigger"
                          + " WHERE AllergyDefNumList LIKE '% " + POut.String(allergyDef.AllergyDefNum.ToString()) + " %'";         // '% <code> %' so that we can get exact matches.
                break;

            case "EhrLabResult":                    //match loinc only, no longer
                ehrLabResult = (EhrLabResult)triggerObject;
                //TODO: TriggerObjectMessage
                command = "SELECT * FROM ehrtrigger WHERE "
                          + "(LabLoincList LIKE '% " + ehrLabResult.ObservationIdentifierID + " %'"                  //LOINC may be in one of two fields
                          + "OR LabLoincList LIKE '% " + ehrLabResult.ObservationIdentifierIDAlt + " %')";           //LOINC may be in one of two fields
                break;

            case "Patient":
                pat = (Patient)triggerObject;
                List <string> triggerNums = new List <string>();
                //TODO: TriggerObjectMessage
                command = "SELECT * FROM ehrtrigger WHERE DemographicsList !=''";
                List <EhrTrigger> triggers = Crud.EhrTriggerCrud.SelectMany(command);
                for (int i = 0; i < triggers.Count; i++)
                {
                    string[] arrayDemoItems = triggers[i].DemographicsList.Split(new string[] { " " }, StringSplitOptions.RemoveEmptyEntries);
                    for (int j = 0; j < arrayDemoItems.Length; j++)
                    {
                        switch (arrayDemoItems[j].Split(',')[0])
                        {
                        case "age":
                            int val = PIn.Int(Regex.Match(arrayDemoItems[j], @"\d+").Value);
                            if (arrayDemoItems[j].Contains("="))                                             //=, >=, or <=
                            {
                                if (val == pat.Age)
                                {
                                    triggerNums.Add(triggers[i].EhrTriggerNum.ToString());
                                    break;
                                }
                            }
                            if (arrayDemoItems[j].Contains("<"))
                            {
                                if (pat.Age < val)
                                {
                                    triggerNums.Add(triggers[i].EhrTriggerNum.ToString());
                                    break;
                                }
                            }
                            if (arrayDemoItems[j].Contains(">"))
                            {
                                if (pat.Age > val)
                                {
                                    triggerNums.Add(triggers[i].EhrTriggerNum.ToString());
                                    break;
                                }
                            }
                            //should never happen, age element didn't contain a comparator
                            break;

                        case "gender":
                            if (arrayDemoItems[j].Split(',')[0].StartsWith(pat.Gender.ToString()))
                            {
                                triggerNums.Add(triggers[i].EhrTriggerNum.ToString());
                            }
                            break;

                        default:
                            break;                                            //should never happen
                        }
                    }
                }
                triggerNums.Add("-1");                        //to ensure the querry is valid.
                command = "SELECT * FROM ehrTrigger WHERE EhrTriggerNum IN (" + String.Join(",", triggerNums) + ")";
                break;

            case "Vitalsign":
                List <string> trigNums = new List <string>();
                vitalsign = (Vitalsign)triggerObject;
                command   = "SELECT * FROM ehrtrigger WHERE VitalLoincList !=''";
                List <EhrTrigger> triggersVit = Crud.EhrTriggerCrud.SelectMany(command);
                for (int i = 0; i < triggersVit.Count; i++)
                {
                    string[] arrayVitalItems = triggersVit[i].VitalLoincList.Split(new string[] { " " }, StringSplitOptions.RemoveEmptyEntries);
                    for (int j = 0; j < arrayVitalItems.Length; j++)
                    {
                        double val = PIn.Double(Regex.Match(arrayVitalItems[j], @"\d+(.(\d+))*").Value);                             //decimal value w or w/o decimal.
                        switch (arrayVitalItems[j].Split(',')[0])
                        {
                        case "height":
                            if (arrayVitalItems[j].Contains("="))                                             //=, >=, or <=
                            {
                                if (vitalsign.Height == val)
                                {
                                    trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
                                    break;
                                }
                            }
                            if (arrayVitalItems[j].Contains("<"))
                            {
                                if (vitalsign.Height < val)
                                {
                                    trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
                                    break;
                                }
                            }
                            if (arrayVitalItems[j].Contains(">"))
                            {
                                if (vitalsign.Height > val)
                                {
                                    trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
                                    break;
                                }
                            }
                            //should never happen, Height element didn't contain a comparator
                            break;

                        case "weight":
                            if (arrayVitalItems[j].Contains("="))                                             //=, >=, or <=
                            {
                                if (vitalsign.Weight == val)
                                {
                                    trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
                                    break;
                                }
                            }
                            if (arrayVitalItems[j].Contains("<"))
                            {
                                if (vitalsign.Weight < val)
                                {
                                    trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
                                    break;
                                }
                            }
                            if (arrayVitalItems[j].Contains(">"))
                            {
                                if (vitalsign.Weight > val)
                                {
                                    trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
                                    break;
                                }
                            }
                            break;

                        case "BMI":
                            float BMI = Vitalsigns.CalcBMI(vitalsign.Weight, vitalsign.Height);
                            if (arrayVitalItems[j].Contains("="))                                             //=, >=, or <=
                            {
                                if (BMI == val)
                                {
                                    trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
                                    break;
                                }
                            }
                            if (arrayVitalItems[j].Contains("<"))
                            {
                                if (BMI < val)
                                {
                                    trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
                                    break;
                                }
                            }
                            if (arrayVitalItems[j].Contains(">"))
                            {
                                if (BMI > val)
                                {
                                    trigNums.Add(triggersVit[i].EhrTriggerNum.ToString());
                                    break;
                                }
                            }
                            break;

                        case "BP":
                            //TODO
                            break;
                        }                //end switch
                    }
                }                        //End Triggers Vit
                trigNums.Add("-1");      //to ensure the querry is valid.
                command = "SELECT * FROM ehrTrigger WHERE EhrTriggerNum IN (" + String.Join(",", trigNums) + ")";
                break;

            default:
                //command="SELECT * FROM ehrtrigger WHERE false";//should not return any results.
                return(null);

                                        #if DEBUG
                throw new Exception(triggerObject.GetType().ToString() + " object not implemented as intervention trigger yet. Add to the list above to handle.");
                                        #endif
                //break;
            }
            List <EhrTrigger> listEhrTriggers = Crud.EhrTriggerCrud.SelectMany(command);
            if (listEhrTriggers.Count == 0)
            {
                return(null);               //no triggers matched.
            }
            //Check for MatchCardinality.One type triggers.----------------------------------------------------------------------------
            for (int i = 0; i < listEhrTriggers.Count; i++)
            {
                if (listEhrTriggers[i].Cardinality != MatchCardinality.One)
                {
                    continue;
                }
                string triggerMessage = listEhrTriggers[i].Description + ":\r\n"; //Example:"Patient over 55:\r\n"
                triggerMessage += triggerObjectMessage;                           //Example:"  -Patient Age 67\r\n"
                List <object> ListObjectMatches = new List <object>();
                ListObjectMatches.Add(triggerObject);
                CDSIntervention cdsi = new CDSIntervention();
                cdsi.EhrTrigger          = listEhrTriggers[i];
                cdsi.InterventionMessage = triggerMessage;
                cdsi.TriggerObjects      = ListObjectMatches;
                retVal.Add(cdsi);
            }
            //Fill object lists to be checked-------------------------------------------------------------------------------------------------
            List <Allergy>    ListAllergy    = Allergies.GetAll(PatCur.PatNum, false);
            List <Disease>    ListDisease    = Diseases.Refresh(PatCur.PatNum, true);
            List <DiseaseDef> ListDiseaseDef = new List <DiseaseDef>();
            List <EhrLab>     ListEhrLab     = EhrLabs.GetAllForPat(PatCur.PatNum);
            //List<EhrLabResult> ListEhrLabResults=null;//Lab results are stored in a list in the EhrLab object.
            List <MedicationPat> ListMedicationPat = MedicationPats.Refresh(PatCur.PatNum, false);
            List <AllergyDef>    ListAllergyDef    = new List <AllergyDef>();
            for (int i = 0; i < ListAllergy.Count; i++)
            {
                ListAllergyDef.Add(AllergyDefs.GetOne(ListAllergy[i].AllergyDefNum));
            }
            for (int i = 0; i < ListDisease.Count; i++)
            {
                ListDiseaseDef.Add(DiseaseDefs.GetItem(ListDisease[i].DiseaseDefNum));
            }
            for (int i = 0; i < listEhrTriggers.Count; i++)
            {
                if (listEhrTriggers[i].Cardinality == MatchCardinality.One)
                {
                    continue;                    //we handled these above.
                }
                string triggerMessage = listEhrTriggers[i].Description + ":\r\n";
                triggerMessage += triggerObjectMessage;
                List <object> ListObjectMatches = new List <object>();            //Allergy, Disease, LabPanels, MedicationPat, Patient, VaccinePat
                ListObjectMatches.Add(triggerObject);
                //Allergy-----------------------------------------------------------------------------------------------------------------------
                //allergy.snomedreaction
                //allergy.AllergyDefNum>>AllergyDef.SnomedType
                //allergy.AllergyDefNum>>AllergyDef.SnomedAllergyTo
                //allergy.AllergyDefNum>>AllergyDef.MedicationNum>>Medication.RxCui
                //Disease-----------------------------------------------------------------------------------------------------------------------
                //Disease.DiseaseDefNum>>DiseaseDef.ICD9Code
                //Disease.DiseaseDefNum>>DiseaseDef.SnomedCode
                //Disease.DiseaseDefNum>>DiseaseDef.Icd10Code
                //LabPanels---------------------------------------------------------------------------------------------------------------------
                //LabPanel.LabPanelNum<<LabResult.TestId (Loinc)
                //LabPanel.LabPanelNum<<LabResult.ObsValue (Loinc)
                //LabPanel.LabPanelNum<<LabResult.ObsRange (Loinc)
                //MedicationPat-----------------------------------------------------------------------------------------------------------------
                //MedicationPat.RxCui
                //MedicationPat.MedicationNum>>Medication.RxCui
                //Patient>>Demographics---------------------------------------------------------------------------------------------------------
                //Patient.Gender
                //Patient.Birthdate (Loinc age?)
                //Patient.SmokingSnoMed
                //RxPat-------------------------------------------------------------------------------------------------------------------------
                //Do not check RxPat. It is useless.
                //VaccinePat--------------------------------------------------------------------------------------------------------------------
                //VaccinePat.VaccineDefNum>>VaccineDef.CVXCode
                //VitalSign---------------------------------------------------------------------------------------------------------------------
                //VitalSign.Height (Loinc)
                //VitalSign.Weight (Loinc)
                //VitalSign.BpSystolic (Loinc)
                //VitalSign.BpDiastolic (Loinc)
                //VitalSign.WeightCode (Snomed)
                //VitalSign.PregDiseaseNum (Snomed)
                //Use object matches to check if required conditions are met-------------------------------------------------------------------------------
                switch (listEhrTriggers[i].Cardinality)
                {
                case MatchCardinality.One:
                    //should never get here, handled above.
                    continue;

                case MatchCardinality.OneOfEachCategory:                        //falls through to two or more, but then branches at the end of the case statement.
                case MatchCardinality.TwoOrMore:
                    //if(ListObjectMatches.Count<2) {
                    //	continue;//Must match at least two objects for this category.
                    //}
                    //Medication
                    for (int m = 0; m < ListMedicationPat.Count; m++)
                    {
                        if (listEhrTriggers[i].MedicationNumList.Contains(" " + ListMedicationPat[m].MedicationNum + " "))
                        {
                            ListObjectMatches.Add(ListMedicationPat[m]);
                            continue;
                        }
                        if (ListMedicationPat[m].RxCui != 0 &&
                            listEhrTriggers[i].RxCuiList.Contains(" " + ListMedicationPat[m].RxCui + " "))
                        {
                            ListObjectMatches.Add(ListMedicationPat[m]);
                            continue;
                        }
                    }
                    //Allergy
                    for (int a = 0; a < ListAllergy.Count; a++)
                    {
                        if (listEhrTriggers[i].AllergyDefNumList.Contains(" " + ListAllergy[a].AllergyDefNum + " "))
                        {
                            ListObjectMatches.Add(AllergyDefs.GetOne(ListAllergy[a].AllergyDefNum));
                            triggerMessage += "  -(Allergy) " + AllergyDefs.GetOne(ListAllergy[a].AllergyDefNum).Description + "\r\n";
                            continue;
                        }
                    }
                    //Problem
                    for (int d = 0; d < ListDiseaseDef.Count; d++)
                    {
                        if (ListDiseaseDef[d].ICD9Code != "" &&
                            listEhrTriggers[i].ProblemIcd9List.Contains(" " + ListDiseaseDef[d].ICD9Code + " "))
                        {
                            ListObjectMatches.Add(ListDiseaseDef[d]);
                            triggerMessage += "  -(ICD9) " + ICD9s.GetByCode(ListDiseaseDef[d].ICD9Code).Description + "\r\n";
                            continue;
                        }
                        if (ListDiseaseDef[d].Icd10Code != "" &&
                            listEhrTriggers[i].ProblemIcd10List.Contains(" " + ListDiseaseDef[d].Icd10Code + " "))
                        {
                            ListObjectMatches.Add(ListDiseaseDef[d]);
                            triggerMessage += "  -(Icd10) " + Icd10s.GetByCode(ListDiseaseDef[d].Icd10Code).Description + "\r\n";
                            continue;
                        }
                        if (ListDiseaseDef[d].SnomedCode != "" &&
                            listEhrTriggers[i].ProblemSnomedList.Contains(" " + ListDiseaseDef[d].SnomedCode + " "))
                        {
                            ListObjectMatches.Add(ListDiseaseDef[d]);
                            triggerMessage += "  -(Snomed) " + Snomeds.GetByCode(ListDiseaseDef[d].SnomedCode).Description + "\r\n";
                            continue;
                        }
                        if (listEhrTriggers[i].ProblemDefNumList.Contains(" " + ListDiseaseDef[d].DiseaseDefNum + " "))
                        {
                            ListObjectMatches.Add(ListDiseaseDef[d]);
                            triggerMessage += "  -(Problem Def) " + ListDiseaseDef[d].DiseaseName + "\r\n";
                            continue;
                        }
                    }
                    //Vital
                    //TODO
                    //Age
                    //TODO
                    //Gender
                    //TODO
                    //Lab Result
                    for (int l = 0; l < ListEhrLab.Count; l++)
                    {
                        for (int r = 0; r < ListEhrLab[l].ListEhrLabResults.Count; r++)
                        {
                            if (listEhrTriggers[i].LabLoincList.Contains(" " + ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierID + " ") ||
                                listEhrTriggers[i].LabLoincList.Contains(" " + ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierIDAlt + " "))
                            {
                                ListObjectMatches.Add(ListEhrLab[l].ListEhrLabResults[r]);
                                if (ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierID != "")                                       //should almost always be the case.
                                {
                                    triggerMessage += "  -(LOINC) " + Loincs.GetByCode(ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierID).NameShort + "\r\n";
                                }
                                else if (ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierID != "")
                                {
                                    triggerMessage += "  -(LOINC) " + Loincs.GetByCode(ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierIDAlt).NameShort + "\r\n";
                                }
                                else if (ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierText != "")
                                {
                                    triggerMessage += "  -(LOINC) " + ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierText + "\r\n";
                                }
                                else if (ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierTextAlt != "")
                                {
                                    triggerMessage += "  -(LOINC) " + ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierTextAlt + "\r\n";
                                }
                                else if (ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierID != "")
                                {
                                    triggerMessage += "  -(LOINC) " + ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierID + "\r\n";
                                }
                                else if (ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierIDAlt != "")
                                {
                                    triggerMessage += "  -(LOINC) " + ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierIDAlt + "\r\n";
                                }
                                else if (ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierTextOriginal != "")
                                {
                                    triggerMessage += "  -(LOINC) " + ListEhrLab[l].ListEhrLabResults[r].ObservationIdentifierTextOriginal + "\r\n";
                                }
                                else
                                {
                                    triggerMessage += "  -(LOINC) Unknown code.\r\n";                                          //should never happen.
                                }
                                continue;
                            }
                        }
                    }
                    ListObjectMatches = RemoveDuplicateObjectsHelper(ListObjectMatches);
                    if (listEhrTriggers[i].Cardinality == MatchCardinality.TwoOrMore && ListObjectMatches.Count < 2)
                    {
                        continue;                                //next trigger, do not add to retVal
                    }
                    if (listEhrTriggers[i].Cardinality == MatchCardinality.OneOfEachCategory && !OneOfEachCategoryHelper(listEhrTriggers[i], ListObjectMatches))
                    {
                        continue;
                    }
                    break;

                case MatchCardinality.All:
                    bool          allConditionsMet = true;
                    List <string> MatchedCodes     = getCodesFromListHelper(ListObjectMatches);                     //new List<string>();
                    //Match all Icd9Codes-------------------------------------------------------------------------------------------------------------------------------------------------
                    string[] arrayIcd9Codes = listEhrTriggers[i].ProblemIcd9List.Split(new string[] { " " }, StringSplitOptions.RemoveEmptyEntries);
                    for (int c = 0; c < arrayIcd9Codes.Length; c++)
                    {
                        if (MatchedCodes.Contains(arrayIcd9Codes[i]))
                        {
                            continue;                                    //found required code
                        }
                        //required code not found, set allConditionsMet to false and continue to next trigger
                        allConditionsMet = false;
                        break;
                    }
                    if (!allConditionsMet)
                    {
                        continue;                                //next trigger
                    }
                    //Match all Icd10Codes------------------------------------------------------------------------------------------------------------------------------------------------
                    string[] arrayIcd10Codes = listEhrTriggers[i].ProblemIcd10List.Split(new string[] { " " }, StringSplitOptions.RemoveEmptyEntries);
                    for (int c = 0; c < arrayIcd10Codes.Length; c++)
                    {
                        if (MatchedCodes.Contains(arrayIcd10Codes[i]))
                        {
                            continue;                                    //found required code
                        }
                        //required code not found, set allConditionsMet to false and continue to next trigger
                        allConditionsMet = false;
                        break;
                    }
                    if (!allConditionsMet)
                    {
                        continue;                                //next trigger
                    }
                    //Match all SnomedCodes-----------------------------------------------------------------------------------------------------------------------------------------------
                    string[] arraySnomedCodes = listEhrTriggers[i].ProblemSnomedList.Split(new string[] { " " }, StringSplitOptions.RemoveEmptyEntries);
                    for (int c = 0; c < arraySnomedCodes.Length; c++)
                    {
                        if (MatchedCodes.Contains(arraySnomedCodes[i]))
                        {
                            continue;                                    //found required code
                        }
                        //required code not found, set allConditionsMet to false and continue to next trigger
                        allConditionsMet = false;
                        break;
                    }
                    if (!allConditionsMet)
                    {
                        continue;                                //next trigger
                    }
                    //Match all CvxCodes--------------------------------------------------------------------------------------------------------------------------------------------------
                    string[] arrayCvxCodes = listEhrTriggers[i].CvxList.Split(new string[] { " " }, StringSplitOptions.RemoveEmptyEntries);
                    for (int c = 0; c < arrayCvxCodes.Length; c++)
                    {
                        if (MatchedCodes.Contains(arrayCvxCodes[i]))
                        {
                            continue;                                    //found required code
                        }
                        //required code not found, set allConditionsMet to false and continue to next trigger
                        allConditionsMet = false;
                        break;
                    }
                    if (!allConditionsMet)
                    {
                        continue;                                //next trigger, do not add to retval
                    }
                    //Match all LoincCodes------------------------------------------------------------------------------------------------------------------------------------------------
                    string[] arrayLoincCodes = listEhrTriggers[i].LabLoincList.Split(new string[] { " " }, StringSplitOptions.RemoveEmptyEntries);
                    for (int c = 0; c < arrayLoincCodes.Length; c++)
                    {
                        if (MatchedCodes.Contains(arrayLoincCodes[i]))
                        {
                            continue;                                    //found required code
                        }
                        //required code not found, set allConditionsMet to false and continue to next trigger
                        allConditionsMet = false;
                        break;
                    }
                    if (!allConditionsMet)
                    {
                        continue;                                //next trigger, do not add to retval
                    }
                    //TODO:with values
                    //Match all Vitals----------------------------------------------------------------------------------------------------------------------------------------------------
                    //TODO:with values
                    //Match all Demographics---------------------------------------------------------------------------------------------------------------------------------------------
                    //if(listEhrTriggers[i].DemographicAgeGreaterThan!=0){
                    //	if(PatCur.Birthdate.Year>1880 && PatCur.Birthdate.AddYears(listEhrTriggers[i].DemographicAgeGreaterThan)>DateTime.Now){//patient too young
                    //		continue;//next trigger
                    //	}
                    //}
                    //if(listEhrTriggers[i].DemographicAgeLessThan!=0){
                    //	if(PatCur.Birthdate.Year>1880 && PatCur.Birthdate.AddYears(listEhrTriggers[i].DemographicAgeGreaterThan)<DateTime.Now){//patient too old
                    //		continue;//next trigger
                    //	}
                    //}
                    //if(listEhrTriggers[i].DemographicGender!=""){
                    //	if(!listEhrTriggers[i].DemographicGender.Contains(PatCur.Gender.ToString())){//Patient Gender not in gender list of trigger
                    //		continue;//next trigger
                    //	}
                    //}
                    //TODO: construct trigger message using all the codes in the trigger.
                    break;
                }                //end switch trigger cardinality
                //retVal.Add(triggerMessage,ListObjectMatches);
                CDSIntervention cdsi = new CDSIntervention();
                cdsi.EhrTrigger          = listEhrTriggers[i];
                cdsi.InterventionMessage = triggerMessage;
                cdsi.TriggerObjects      = ListObjectMatches;
                retVal.Add(cdsi);
            }            //end triggers
            return(retVal);
        }