public void CompareAveragingWithMSstats()
{
var srmDocument = LoadRatPlasmaDocument();
var documentContainer = new MemoryDocumentContainer();
documentContainer.SetDocument(documentContainer.Document, srmDocument);
GroupComparisonModel model = new GroupComparisonModel(documentContainer, null);
model.GroupComparisonDef = GroupComparisonDef.EMPTY.ChangeControlAnnotation("Condition")
.ChangeControlValue("Healthy")
.ChangeIdentityAnnotation("BioReplicate")
.ChangeSummarizationMethod(SummarizationMethod.AVERAGING)
.ChangePerProtein(false);
var expectedValues = MsStatsTestUtil.ReadExpectedResults(typeof (MSstatsAveragingTest),
"RatPlasmaTestingResult.csv");
var groupComparer = new GroupComparer(model.GroupComparisonDef, srmDocument, new QrFactorizationCache());
foreach (var protein in srmDocument.PeptideGroups)
{
foreach (var peptide in protein.Peptides)
{
var result = groupComparer.CalculateFoldChange(new GroupComparisonSelector(protein, peptide, IsotopeLabelType.light, null, new GroupIdentifier("Diseased")), null);
var expectedResult = expectedValues[peptide.Peptide.Sequence];
Assert.AreEqual(expectedResult.EstimatedValue, result.LinearFitResult.EstimatedValue,
(expectedResult.StandardError + result.LinearFitResult.StandardError) * 2, peptide.Peptide.Sequence);
}
}
}
public ModelChangeSupport(GroupComparisonModel model, Control control, Action <GroupComparisonModel> eventHandler)
{
_model = model;
_control = control;
_eventHandler = eventHandler;
_control.HandleCreated += ControlHandleCreated;
_control.HandleDestroyed += ControlHandleDestroyed;
}
public ModelChangeSupport(GroupComparisonModel model, Control control, Action<GroupComparisonModel> eventHandler)
{
_model = model;
_control = control;
_eventHandler = eventHandler;
_control.HandleCreated += ControlHandleCreated;
_control.HandleDestroyed += ControlHandleDestroyed;
}
public FoldChangeBindingSource(GroupComparisonModel groupComparisonModel)
{
_container = new Container();
GroupComparisonModel = groupComparisonModel;
_taskScheduler = TaskScheduler.FromCurrentSynchronizationContext();
}