private void CrossEntropy2(ref StateDependentGammaInfo gammaInfo, double tempRareEvent)
{
IBoolean tempRareEventExpression = new EqualTo(_reExpression, new ConstantValue(tempRareEvent));
var startPC = Enumerable.Repeat(1.0, _reactions.NumReactions).ToArray();
var endPC = new double[_reactions.NumReactions];
var rateUpdateMethod = new ReactionRatesUpdateMethod(_reactions.UpdateRatesIteration2);
for (int i = 0; i < _crossEntropyRuns; i++)
{
StartRealization();
var n = new List <int[]>();
var lambda = new List <double[]>();
double weight = 1.0;
for (int j = 0; j < _reactions.NumReactions; j++)
{
n.Add(new int[(gammaInfo.IntermediatePropensityCutoff[j]).Length + 1]);
lambda.Add(new double[(gammaInfo.IntermediatePropensityCutoff[j]).Length + 1]);
}
while (CurrentTime < duration)
{
if (tempRareEventExpression.Value)
{
gammaInfo.UpdateGamma(weight, n, lambda);
break;
}
GenericStepOnce(ref weight, gammaInfo, ref startPC, ref endPC, ref n, ref lambda, rateUpdateMethod, ref _binIndex, null);
}
}
gammaInfo.SetIntermediateGamma();
}
private void CrossEntropy1(ref StateDependentGammaInfo gammaInfo, ref double intermediateRareEvent, ref double[] startPC, ref double[] endPC, ref bool rareEventFlag)
{
var maxRareEventValue = new double[_crossEntropyRuns];
int counter = 0;
var rateUpdateMethod = new ReactionRatesUpdateMethod(_reactions.UpdateRatesIteration1);
var binEdgesUpdateMethod = new BinEdgesUpdateMethod(UpdateBinEdges);
for (int i = 0; i < _crossEntropyRuns; i++)
{
StartRealization();
double currentMin = _rareEventType * (_rareEventValue - _reExpression.Value);
var n = new List <int[]>();
var lambda = new List <double[]>();
double weight = 1.0;
for (int j = 0; j < _reactions.NumReactions; j++)
{
n.Add(new int[(gammaInfo.IntermediatePropensityCutoff[j]).Length + 1]);
lambda.Add(new double[(gammaInfo.IntermediatePropensityCutoff[j]).Length + 1]);
}
while (CurrentTime < duration)
{
if (_rareEventTest.Value)
{
counter++;
gammaInfo.UpdateGamma(weight, n, lambda);
break;
}
GenericStepOnce(ref weight, gammaInfo, ref startPC, ref endPC, ref n, ref lambda, rateUpdateMethod, ref _gammaIndex, binEdgesUpdateMethod);
double tempMin = _rareEventType * (_rareEventValue - _reExpression.Value);
currentMin = Math.Min(currentMin, tempMin);
}
maxRareEventValue[i] = currentMin;
}
Array.Sort(maxRareEventValue);
double ireComp = maxRareEventValue[(int)Math.Ceiling(_crossEntropyRuns * _crossEntropyThreshold)];
double pastIntermediateRareEvent = intermediateRareEvent;
intermediateRareEvent = ireComp < 0 ? _rareEventValue : _rareEventType * (_rareEventValue - ireComp);
if ((pastIntermediateRareEvent - intermediateRareEvent) * _rareEventType >= 0)
{
_crossEntropyThreshold *= 0.8;
Console.WriteLine("Cross entropy threshold changed to : " + _crossEntropyThreshold);
if (_crossEntropyThreshold * _crossEntropyRuns * 0.8 < _crossEntropyMinDataSize)
{
_crossEntropyRuns = (int)Math.Ceiling(_crossEntropyMinDataSize / _crossEntropyThreshold);
Console.WriteLine("Number of cross entropy simulations changed to : " + _crossEntropyRuns);
}
}
if (intermediateRareEvent >= _rareEventValue && counter >= (int)(_crossEntropyRuns * _crossEntropyThreshold))
{
rareEventFlag = true;
gammaInfo.SetIntermediateGamma();
}
}
