private void InitializeGlobalMutex() { // get application GUID as defined in AssemblyInfo.cs string appGuid = ((GuidAttribute)Assembly.GetExecutingAssembly().GetCustomAttributes(typeof(GuidAttribute), false).GetValue(0)).Value.ToString(); // unique id for global mutex - Global prefix means it is global to the machine mutexId_ = string.Format("Global\\{{{0}}}", appGuid); // edited by Jeremy Wiebe to add example of setting up security for multi-user usage // edited by 'Marc' to work also on localized systems (don't use just "Everyone") MutexAccessRule allowEveryoneRule = new MutexAccessRule(new SecurityIdentifier(WellKnownSidType.WorldSid, null), MutexRights.FullControl, AccessControlType.Allow); // MutexSecurity securitySettings = new MutexSecurity(); SecuritySettings.AddAccessRule(allowEveryoneRule); }