public void should_update_elderly_ICRP_organ_volumes()
{
var meanStdRatios = new[]
{
new { organ = CoreConstants.Organ.ArterialBlood, maleRatio = 0.05, femaleRatio = 0.05 },
new { organ = CoreConstants.Organ.Bone, maleRatio = 0.011059, femaleRatio = 0.01 },
new { organ = CoreConstants.Organ.Gonads, maleRatio = 0.05, femaleRatio = 0.05 },
new { organ = CoreConstants.Organ.Kidney, maleRatio = 0.24628, femaleRatio = 0.25 },
new { organ = CoreConstants.Organ.LargeIntestine, maleRatio = 0.14, femaleRatio = 0.14 },
new { organ = CoreConstants.Organ.Liver, maleRatio = 0.25, femaleRatio = 0.25 },
new { organ = CoreConstants.Organ.Pancreas, maleRatio = 0.2689, femaleRatio = 0.28 },
new { organ = CoreConstants.Organ.Skin, maleRatio = 0.05, femaleRatio = 0.05 },
new { organ = CoreConstants.Organ.VenousBlood, maleRatio = 0.05, femaleRatio = 0.05 }
};
foreach (var meanStdRatio in meanStdRatios)
{
var volumeParameters = _parameterDistributionRepository.All().Where(pd => isElderlyICRPVolumeParameterIn(pd, meanStdRatio.organ));
foreach (var volumeParameter in volumeParameters)
{
if (meanStdRatio.organ.Equals(CoreConstants.Organ.Liver) && volumeParameter.Gender.Equals(CoreConstants.Gender.Male))
{
continue; //no update for this combination
}
var ratio = volumeParameter.Deviation / volumeParameter.Mean;
var expectedRatio = volumeParameter.Gender.Equals(CoreConstants.Gender.Male) ? meanStdRatio.maleRatio : meanStdRatio.femaleRatio;
ratio.ShouldBeEqualTo(expectedRatio, 1e-3, $"{meanStdRatio.organ}.{volumeParameter.Gender}.{volumeParameter.Age} years");
}
}
}
public void should_update_elderly_ICRP_organ_volumes()
{
var meanStdRatios = new[]
{
new { organ = ARTERIAL_BLOOD, maleRatio = 0.05, femaleRatio = 0.05 },
new { organ = BONE, maleRatio = 0.011059, femaleRatio = 0.01 },
new { organ = GONADS, maleRatio = 0.05, femaleRatio = 0.05 },
new { organ = KIDNEY, maleRatio = 0.24628, femaleRatio = 0.25 },
new { organ = LARGE_INTESTINE, maleRatio = 0.14, femaleRatio = 0.14 },
new { organ = LIVER, maleRatio = 0.25, femaleRatio = 0.25 },
new { organ = PANCREAS, maleRatio = 0.2689, femaleRatio = 0.28 },
new { organ = SKIN, maleRatio = 0.05, femaleRatio = 0.05 },
new { organ = VENOUS_BLOOD, maleRatio = 0.05, femaleRatio = 0.05 }
};
foreach (var meanStdRatio in meanStdRatios)
{
var volumeParameters = _parameterDistributionRepository.All().Where(pd => isElderlyICRPVolumeParameterIn(pd, meanStdRatio.organ));
foreach (var volumeParameter in volumeParameters)
{
if (meanStdRatio.organ.Equals(LIVER) && volumeParameter.Gender.Equals(CoreConstants.Gender.MALE))
{
continue; //no update for this combination
}
var ratio = volumeParameter.Deviation / volumeParameter.Mean;
var expectedRatio = volumeParameter.Gender.Equals(CoreConstants.Gender.MALE) ? meanStdRatio.maleRatio : meanStdRatio.femaleRatio;
ratio.ShouldBeEqualTo(expectedRatio, 1e-3, $"{meanStdRatio.organ}.{volumeParameter.Gender}.{volumeParameter.Age} years");
}
}
}
public void should_update_nhanes_values()
{
var nhanesParams = _parameterDistributionRepository.All().Where(pd => pd.Population.EndsWith("NHANES_1997")).ToList();
var bwParams = nhanesParams.Where(p => p.ParameterName.Equals(CoreConstants.Parameters.MEAN_WEIGHT)).ToList();
var heightParams = nhanesParams.Where(p => p.ParameterName.Equals(CoreConstants.Parameters.MEAN_HEIGHT)).ToList();
var volumeParams = nhanesParams.Where(p => p.ParameterName.Equals(Constants.Parameters.VOLUME)).ToList();
//check number of new bw/height/volume parameters
(bwParams.Count + heightParams.Count + volumeParams.Count).ShouldBeEqualTo(1420);
//check some height standard deviations
var teenHeightParams = heightParams.Where(p => p.Age == 13 || p.Age == 15).ToList();
teenHeightParams.Count.ShouldBeEqualTo(2 * 2 * 3); //2 age groups*2genders*3populations
teenHeightParams.Each(p => p.Deviation.ShouldBeGreaterThan(0.6));
}
public void should_properly_set_some_value_origins()
{
var agesWithFilledValueOrigins = new double[] { 0, 1, 5, 10, 15, 30, 40, 50, 60, 70, 80, 90, 100 };
var icrpParams = _parameterDistributionRepository.All()
.Where(p => p.Population.Equals(CoreConstants.Population.ICRP))
.Where(p => p.ParameterName.IsOneOf(
Constants.Parameters.VOLUME,
CoreConstants.Parameters.BLOOD_FLOW)).ToList();
icrpParams.Count.ShouldBeGreaterThanOrEqualTo(agesWithFilledValueOrigins.Length * 2 * 2); //2 Genders * 2 parameters per age
foreach (var param in icrpParams)
{
if (param.Age.IsOneOf(agesWithFilledValueOrigins))
{
param.ValueOrigin.IsUndefined.ShouldBeFalse();
}
else
{
param.ValueOrigin.IsUndefined.ShouldBeTrue();
}
}
}
public IEnumerable <ParameterDistributionMetaData> AllParameterDistributionsFor(OriginData originData)
{
return(distributedParameterMetaDataFor(_parameterDistributionRepository.All(), originData));
}
