public GeneticTestingResultRow(GeneticTestResult geneticTestResult, bool canDelete)
{
this.geneticTestResult = geneticTestResult;
this.geneticTestResult.AddHandlersWithLoad(TestResultChanged, null, null);
InitializeComponent();
updateUI();
UIUtils.fillComboBoxFromLookups(resultSignificanceComboBox, "tblRiskGeneticTest", "resultSignificance", true);
List <String> geneList = SessionManager.Instance.MetaData.GeneticTests.GetGenesInPanel(geneticTestResult.owningGeneticTest.panelID);
UIUtils.fillComboBoxFromList(geneNameComboBox, geneList, false);
FillDataFromTestResult(geneticTestResult);
//deleteButton.Visible = canDelete;
geneNameComboBox.Visible = canDelete;
geneNameTextBox.Visible = !canDelete;
populateMutationComboBoxes();
initialized = true;
}
private void FillDataFromTestResult(GeneticTestResult geneticTestResult)
{
if (geneticTestResult != null)
{
if (this.InvokeRequired)
{
FillDataCallback fdc = new FillDataCallback(FillDataFromTestResult);
object[] args = new object[1];
args[0] = geneticTestResult;
this.Invoke(fdc, args);
}
else
{
if (!string.IsNullOrEmpty(geneticTestResult.geneName))
{
geneNameComboBox.Text = geneticTestResult.geneName;
geneNameTextBox.Text = geneticTestResult.geneName;
}
else
{
geneNameTextBox.ReadOnly = false;
}
mutationNameComboBox.Text = geneticTestResult.mutationName;
mutationAAComboBox.Text = geneticTestResult.mutationAA;
if (geneticTestResult.resultSignificance != null)
{
if (resultSignificanceComboBox.Items.Contains(geneticTestResult.resultSignificance) == false)
{
resultSignificanceComboBox.Items.Add(geneticTestResult.resultSignificance);
}
}
resultSignificanceComboBox.Text = geneticTestResult.resultSignificance;
allelicStateComboBox.Text = geneticTestResult.allelicState;
commentsTextBox.Text = geneticTestResult.comments;
var selection = SessionManager.Instance.MetaData.Mutations
.Where(m =>
((MutationObject)m).geneName == geneticTestResult.geneName &&
((MutationObject)m).mutationDNA == geneticTestResult.mutationName);
string lkpresultSignificance = selection.Select(m => ((MutationObject)m).significance).FirstOrDefault();
if (lkpresultSignificance != geneticTestResult.resultSignificance)
{
//BD - VariantSerive
//label1.Visible = true;
}
else
{
label1.Visible = false;
}
}
}
}
public GeneticTestingASOResultRow(GeneticTestResult geneticTestResult, bool canDelete)
{
this.geneticTestResult = geneticTestResult;
this.geneticTestResult.AddHandlersWithLoad(TestResultChanged, null, null);
InitializeComponent();
updateUI();
List <String> geneList = SessionManager.Instance.MetaData.GeneticTests.GetGenesInPanel(geneticTestResult.owningGeneticTest.panelID);
FillDataFromTestResult(geneticTestResult);
//SaveASOData();
deleteButton.Visible = canDelete;
}
public GeneticTestingASOResultRow(GeneticTestResult geneticTestResult, bool canDelete)
{
this.geneticTestResult = geneticTestResult;
this.geneticTestResult.AddHandlersWithLoad(TestResultChanged, null, null);
InitializeComponent();
updateUI();
List<String> geneList = SessionManager.Instance.MetaData.GeneticTests.GetGenesInPanel(geneticTestResult.owningGeneticTest.panelID);
FillDataFromTestResult(geneticTestResult);
//SaveASOData();
deleteButton.Visible = canDelete;
}
private void addResultButton_Click(object sender, EventArgs e)
{
//handles the little '+' button
GeneticTestResult geneticTestResult = new GeneticTestResult(geneticTest);
geneticTestResult.testInstanceID = geneticTest.instanceID;
geneticTest.GeneticTestResults.Add(geneticTestResult);
Control toAdd = null;
if (this.geneticTest.IsASOTest)
{
//make this load known mutations or throw the error message
if (
!geneticTest.owningPMH.RelativeOwningPMH.owningFHx
.HasUniqueNonNegativeGeneticTestResults(
geneticTest.owningPMH.RelativeOwningPMH.relativeID))
{
MessageBox.Show(
"This option is only valid for family histories with a known mutation. " +
"Please enter a positive mutation for a relative of this individual before proceeding.",
"No known positive mutations in this family.",
MessageBoxButtons.OK,
MessageBoxIcon.Information);
this.addResultButton.Visible = true;
this.addResultButton.Enabled = true;
return;
}
else
{
addResultRows();
}
}
else
{
toAdd = new GeneticTestingResultRow(geneticTestResult, true);
}
flowLayoutPanel1.Controls.Add(toAdd);
DoScroll(ScrollEnum.Grow);
}
private void FillDataFromTestResult(GeneticTestResult geneticTestResult)
{
if (geneticTestResult != null)
{
if (this.InvokeRequired)
{
FillDataCallback fdc = new FillDataCallback(FillDataFromTestResult);
object[] args = new object[1];
args[0] = geneticTestResult;
this.Invoke(fdc, args);
}
else
{
allelicStateComboBox.Text = geneticTestResult.allelicState;
commentsTextBox.Text = geneticTestResult.comments;
ASOInfoTextBox.Text = geneticTestResult.GetASOSummary();
ASOResultComboBox.Text = geneticTestResult.ASOResult;
}
}
}
private void addResultRows()
{
HraModelChangedEventArgs args = new HraModelChangedEventArgs(null);
args.Persist = false;
ClearExistingResults();
if (geneticTest.IsASOTest)
{
this.ResultSignificanceNegativeButton.Enabled = false;
this.ResultSignificanceNegativeButton.Visible = false;
List <GeneticTestResult> geneticTestResults = geneticTest.owningPMH.RelativeOwningPMH.owningFHx.
GetUniqueNonNegativeGeneticTestResults(
geneticTest.owningPMH.RelativeOwningPMH.relativeID);
geneticTestResults.Sort(gtrc);
if (geneticTestResults.Count > 0)
{
flowLayoutPanel1.Controls.Add(new GeneticTestingASOResultRowHeader());
this.ResultSignificanceNegativeButton.Visible = true;
this.ResultSignificanceNegativeButton.Enabled = true;
this.ResultSignificanceNegativeButton.Text = "Set results Not Found.";
this.addResultButton.Visible = false;
this.addResultButton.Enabled = false;
}
foreach (GeneticTestResult gtr in geneticTestResults)
{
GeneticTestResult geneticTestResult = new GeneticTestResult(geneticTest);
geneticTestResult.geneName = gtr.geneName;
geneticTestResult.testInstanceID = geneticTest.instanceID;
geneticTestResult.ASOResultSignificance = gtr.resultSignificance;
geneticTestResult.ASOMutationName = gtr.mutationName;
geneticTestResult.ASOMutationAA = gtr.mutationAA;
geneticTestResult.relativeIDofRelative =
gtr.owningGeneticTest.owningPMH.RelativeOwningPMH.relativeID;
geneticTestResult.instanceIDofRelative =
gtr.owningGeneticTest.instanceID;
geneticTestResult.ASOResult = "Unknown";
geneticTest.GeneticTestResults.Add(geneticTestResult);
GeneticTestingASOResultRow row = new GeneticTestingASOResultRow(geneticTestResult, false);
flowLayoutPanel1.Controls.Add(row);
}
}
else
{
List <String> geneList = SessionManager.Instance.MetaData.GeneticTests.GetGenesInPanel(geneticTest.panelID);
if (geneList.Count > 0)
{
flowLayoutPanel1.Controls.Add(new GeneticTestingResultRowHeader());
this.ResultSignificanceNegativeButton.Visible = true;
this.ResultSignificanceNegativeButton.Enabled = true;
}
geneList.Sort();
foreach (String geneName in geneList)
{
GeneticTestResult gtr = geneticTest
.GeneticTestResults
.SingleOrDefault(
r =>
((GeneticTestResult)r).instanceID == geneticTest.instanceID &&
((GeneticTestResult)r).instanceID != 0);
if (gtr == null)
{
gtr = new GeneticTestResult(geneticTest);
gtr.testInstanceID = geneticTest.instanceID;
}
gtr.geneName = geneName;
//TODO turn genetic test results into HRAList and use AddToList
geneticTest.GeneticTestResults.Add(gtr);
Control gtrr = null;
if (geneticTest.IsASOTest)
{
gtrr = new GeneticTestingASOResultRow(gtr, false);
}
else
{
gtrr = new GeneticTestingResultRow(gtr, false);
}
flowLayoutPanel1.Controls.Add(gtrr);
}
}
DoScroll(ScrollEnum.Grow);
}
private static void ProcessPersonNode(XPathNavigator personNode, XPathNavigator riskMean_rootNode, ref Person targetPerson, bool isProband, ref int nextRelIdIfNeeded)
{
string dataroot;
if (isProband)
dataroot = "patientPerson";
else
dataroot = "relationshipHolder";
XPathNavigator dataRootNode = personNode.SelectSingleNode(dataroot);
/////////////////////////
//Age
/////////////////////////
string age_val = personNode.Evaluate("string(subjectOf1/livingEstimatedAge/value/@value)").ToString();
if (string.IsNullOrEmpty(age_val) == false)
{
targetPerson.age = age_val;
}
else
{
age_val = personNode.Evaluate("string(subjectOf1/deceasedEstimatedAge/value/@value)").ToString();
if (string.IsNullOrEmpty(age_val) == false)
{
targetPerson.age = age_val;
}
}
if (String.IsNullOrEmpty(age_val))
{
//try to get age from the birthdate
string birthDateRaw = personNode.Evaluate("string(patientPerson/birthTime/@value)").ToString();
if (!string.IsNullOrEmpty(birthDateRaw))
{
//convert the raw birthdate in YYYYMMDD format to the current age
string[] format = { "yyyyMMdd" }; //official HL7 date format
DateTime birthDate;
if (DateTime.TryParseExact(birthDateRaw,
format,
System.Globalization.CultureInfo.InvariantCulture,
System.Globalization.DateTimeStyles.None,
out birthDate))
{
DateTime today = DateTime.Today;
int age = today.Year - birthDate.Year;
if (birthDate > today.AddYears(-age)) age--;
targetPerson.age = age.ToString();
}
}
}
//////////////////////////
// other basics
//////////////////////////
//old way fails when relative Id isn't integer in source xml/hl7
//targetPerson.relativeID = Convert.ToInt32(dataRootNode.Evaluate("string(id/@extension)").ToString());
int number;
bool resultRelId = Int32.TryParse(dataRootNode.Evaluate("string(id/@extension)").ToString(), out number);
if (resultRelId)
{
targetPerson.relativeID = number;
}
else
{
targetPerson.relativeID = nextRelIdIfNeeded++;
}
targetPerson.name = dataRootNode.Evaluate("string(name/@formatted)").ToString();
targetPerson.firstName = dataRootNode.Evaluate("string(name/@first)").ToString();
targetPerson.lastName = dataRootNode.Evaluate("string(name/@last)").ToString();
targetPerson.homephone = dataRootNode.Evaluate("string(telecom[@use='H']/@value)").ToString();
targetPerson.workphone = dataRootNode.Evaluate("string(telecom[@use='WP']/@value)").ToString();
targetPerson.gender = HL7FormatTranslator.GenderFromHL7(dataRootNode.Evaluate("string(administrativeGenderCode/@code)").ToString());
targetPerson.dob = HL7FormatTranslator.DateFromHL7(dataRootNode.Evaluate("string(birthTime/@value)").ToString()); ;
targetPerson.vitalStatus = HL7FormatTranslator.VitalStatusFromHL7(dataRootNode.Evaluate("string(deceasedInd/@value)").ToString());
int temp_mom_id;
int temp_dad_id;
if (int.TryParse(dataRootNode.Evaluate("string(relative[code/@code='NMTH']/relationshipHolder/id/@extension)").ToString(), out temp_mom_id))
{
targetPerson.motherID = temp_mom_id;
}
if (int.TryParse(dataRootNode.Evaluate("string(relative[code/@code='NFTH']/relationshipHolder/id/@extension)").ToString(), out temp_dad_id))
{
targetPerson.fatherID = temp_dad_id;
}
//////////////////////////
// ethnicity
//////////////////////////
XPathNodeIterator raceIter = dataRootNode.Select("raceCode");
foreach (XPathNavigator raceNode in raceIter)
{
string code = raceNode.Evaluate("string(@code)").ToString();
string displayName = raceNode.Evaluate("string(@displayName)").ToString();
string hraRaceText = HL7FormatTranslator.RaceFromHL7(code, displayName);
if (hraRaceText == "Ashkenazi")
{
targetPerson.isAshkenazi = "Yes";
}
else if (hraRaceText == "Hispanic")
{
targetPerson.isHispanic = "Yes";
}
else
{
Race r = new Race();
r.race = hraRaceText;
targetPerson.Ethnicity.Add(r);
}
}
//SG encodes above in ethnicGroupCode rather than raceCode, so we check these too
XPathNodeIterator ethnicIter = dataRootNode.Select("ethnicGroupCode");
foreach (XPathNavigator ethnicNode in ethnicIter)
{
string code = ethnicNode.Evaluate("string(@code)").ToString();
string displayName = ethnicNode.Evaluate("string(@displayName)").ToString();
string hraEthnicityText = HL7FormatTranslator.EthnicityFromHL7(code, displayName);
if (hraEthnicityText == "Ashkenazi")
{
targetPerson.isAshkenazi = "Yes";
}
else if (hraEthnicityText == "Hispanic or Latino")
{
targetPerson.isHispanic = "Yes";
}
else if (hraEthnicityText == "not Hispanic or Latino")
{
targetPerson.isHispanic = "No";
}
else
{
Race r = new Race();
r.race = hraEthnicityText;
targetPerson.Ethnicity.Add(r);
}
}
//////////////////////////
// Clinical Observations
//////////////////////////
//PRB modified XPath in next to *not* include COs that are for cause of death, which SG duplicates from another CO with that same disease
XPathNodeIterator coIter = personNode.Select(@"subjectOf2/clinicalObservation[not(sourceOf/@typeCode='CAUS')]");
foreach (XPathNavigator coNode in coIter)
{
string coText = coNode.Evaluate("string(code/@displayName)").ToString();
string coCode = coNode.Evaluate("string(code/@code)").ToString();
string coCodeSystem = coNode.Evaluate("string(code/@codeSystemName)").ToString();
string ageLowText = coNode.Evaluate("string(subject/dataEstimatedAge/value/low/@value)").ToString();
string ageHighText = coNode.Evaluate("string(subject/dataEstimatedAge/value/high/@value)").ToString();
string statusCode = coNode.Evaluate("string(statusCode/@code)").ToString();
string coValue = coNode.Evaluate("string(code/qualifier/value/@code)").ToString();
string coAgeDx = HL7FormatTranslator.GetIntFromHL7HighLow(ageLowText, ageHighText);
string hra_tag = riskMean_rootNode.Evaluate("string(row[codeSystem/.='" + coCodeSystem + "'][code/.='" + coCode + "']/Mgh/.)").ToString();
if (string.IsNullOrEmpty(hra_tag) == false)
{
if (string.Compare(hra_tag, "Identical twin", true) == 0)
{
int temp;
if (int.TryParse(coValue, out temp))
{
targetPerson.twinID = temp;
}
}
else
{
if (targetPerson is Patient)
{
Patient p = (Patient)targetPerson;
bool result = processAsRiskFactorClinicalObservation(hra_tag, ref p, coAgeDx, statusCode, coValue);
if (!result)
{
ClincalObservation co = new ClincalObservation(targetPerson.PMH);
co.ClinicalObservation_disease = hra_tag;
co.ClinicalObservation_ageDiagnosis = coAgeDx;
targetPerson.PMH.Observations.Add(co);
}
}
else
{
ClincalObservation co = new ClincalObservation(targetPerson.PMH);
co.ClinicalObservation_disease = hra_tag;
co.ClinicalObservation_ageDiagnosis = coAgeDx;
targetPerson.PMH.Observations.Add(co);
}
}
}
else
{
ClincalObservation co = new ClincalObservation(targetPerson.PMH);
co.ClinicalObservation_disease = coText;
co.ClinicalObservation_ageDiagnosis = coAgeDx;
targetPerson.PMH.Observations.Add(co);
}
}
//////////////////////////
// Cause of Death
//////////////////////////
XPathNavigator cdNav = personNode.SelectSingleNode(@"subjectOf2/clinicalObservation[sourceOf[@typeCode='CAUS']/clinicalObservation/code[(@displayName='death') or (@code='419620001')]]/code[1]");
if (cdNav != null) {
string cdText = cdNav.Evaluate("string(@displayName)").ToString();
string cdCode = cdNav.Evaluate("string(@code)").ToString();
string cdCodeSystem = cdNav.Evaluate("string(@codeSystemName)").ToString();
string cd_hra_tag = riskMean_rootNode.Evaluate("string(row[codeSystem/.='" + cdCodeSystem + "'][code/.='" + cdCode + "']/Mgh/.)").ToString();
if (string.IsNullOrEmpty(cd_hra_tag) == false)
{
targetPerson.causeOfDeath = cd_hra_tag;
}
else
{
targetPerson.causeOfDeath = cdText;
}
}
//////////////////////////
// Genetic Testing
//////////////////////////
//Panels first
XPathNodeIterator gtIter = personNode.Select("subjectOf2/geneticLocus");
List<GeneticTest> panels = new List<GeneticTest>();
List<string> panelNames = new List<string>();
foreach (XPathNavigator gtNode in gtIter)
{
string locusText = gtNode.Evaluate("string(text/.)").ToString();
if (string.IsNullOrEmpty(locusText) == false)
{
if (panelNames.Contains(locusText) == false)
{
GeneticTest new_panel = new GeneticTest(targetPerson.PMH);
new_panel.comments = locusText;
new_panel.GeneticTest_panelID = 34;
panels.Add(new_panel);
panelNames.Add(locusText);
}
}
}
//then results
foreach(GeneticTest panel in panels)
{
XPathNodeIterator resultIter = personNode.Select("subjectOf2/geneticLocus[text/.='" + panel.comments + "']");
foreach (XPathNavigator resultNode in resultIter)
{
string geneName = resultNode.Evaluate("string(value/@displayName)").ToString();
if (string.IsNullOrEmpty(geneName) == false)
{
GeneticTestResult result = new GeneticTestResult(panel);
result.geneName = geneName;
string significance = resultNode.Evaluate("string(component3/sequenceVariation/interpretationCode/@code)").ToString();
result.resultSignificance = significance;
panel.GeneticTestResults.Add(result);
}
}
targetPerson.PMH.GeneticTests.Add(panel);
}
}
private void addResultRows()
{
HraModelChangedEventArgs args = new HraModelChangedEventArgs(null);
args.Persist = false;
ClearExistingResults();
if (geneticTest.IsASOTest)
{
this.ResultSignificanceNegativeButton.Enabled = false;
this.ResultSignificanceNegativeButton.Visible = false;
List<GeneticTestResult> geneticTestResults = geneticTest.owningPMH.RelativeOwningPMH.owningFHx.
GetUniqueNonNegativeGeneticTestResults(
geneticTest.owningPMH.RelativeOwningPMH.relativeID);
geneticTestResults.Sort(gtrc);
if (geneticTestResults.Count > 0)
{
flowLayoutPanel1.Controls.Add(new GeneticTestingASOResultRowHeader());
this.ResultSignificanceNegativeButton.Visible = true;
this.ResultSignificanceNegativeButton.Enabled = true;
this.ResultSignificanceNegativeButton.Text = "Set results Not Found.";
this.addResultButton.Visible = false;
this.addResultButton.Enabled = false;
}
foreach (GeneticTestResult gtr in geneticTestResults)
{
GeneticTestResult geneticTestResult = new GeneticTestResult(geneticTest);
geneticTestResult.geneName = gtr.geneName;
geneticTestResult.testInstanceID = geneticTest.instanceID;
geneticTestResult.ASOResultSignificance = gtr.resultSignificance;
geneticTestResult.ASOMutationName = gtr.mutationName;
geneticTestResult.ASOMutationAA = gtr.mutationAA;
geneticTestResult.relativeIDofRelative =
gtr.owningGeneticTest.owningPMH.RelativeOwningPMH.relativeID;
geneticTestResult.instanceIDofRelative =
gtr.owningGeneticTest.instanceID;
geneticTestResult.ASOResult = "Unknown";
geneticTest.GeneticTestResults.Add(geneticTestResult);
GeneticTestingASOResultRow row = new GeneticTestingASOResultRow(geneticTestResult, false);
flowLayoutPanel1.Controls.Add(row);
}
}
else
{
List<String> geneList = SessionManager.Instance.MetaData.GeneticTests.GetGenesInPanel(geneticTest.panelID);
if (geneList.Count > 0)
{
flowLayoutPanel1.Controls.Add(new GeneticTestingResultRowHeader());
this.ResultSignificanceNegativeButton.Visible = true;
this.ResultSignificanceNegativeButton.Enabled = true;
}
geneList.Sort();
foreach (String geneName in geneList)
{
GeneticTestResult gtr = geneticTest
.GeneticTestResults
.SingleOrDefault(
r =>
((GeneticTestResult)r).instanceID == geneticTest.instanceID &&
((GeneticTestResult)r).instanceID!=0);
if (gtr == null)
{
gtr = new GeneticTestResult(geneticTest);
gtr.testInstanceID = geneticTest.instanceID;
}
gtr.geneName = geneName;
//TODO turn genetic test results into HRAList and use AddToList
geneticTest.GeneticTestResults.Add(gtr);
Control gtrr = null;
if (geneticTest.IsASOTest)
{
gtrr = new GeneticTestingASOResultRow(gtr, false);
}
else
{
gtrr = new GeneticTestingResultRow(gtr, false);
}
flowLayoutPanel1.Controls.Add(gtrr);
}
}
DoScroll(ScrollEnum.Grow);
}
private void addResultButton_Click(object sender, EventArgs e)
{
//handles the little '+' button
GeneticTestResult geneticTestResult = new GeneticTestResult(geneticTest);
geneticTestResult.testInstanceID = geneticTest.instanceID;
geneticTest.GeneticTestResults.Add(geneticTestResult);
Control toAdd = null;
if (this.geneticTest.IsASOTest)
{
//make this load known mutations or throw the error message
if (
!geneticTest.owningPMH.RelativeOwningPMH.owningFHx
.HasUniqueNonNegativeGeneticTestResults(
geneticTest.owningPMH.RelativeOwningPMH.relativeID))
{
MessageBox.Show(
"This option is only valid for family histories with a known mutation. " +
"Please enter a positive mutation for a relative of this individual before proceeding.",
"No known positive mutations in this family.",
MessageBoxButtons.OK,
MessageBoxIcon.Information);
this.addResultButton.Visible = true;
this.addResultButton.Enabled = true;
return;
}
else
{
addResultRows();
}
}
else
{
toAdd = new GeneticTestingResultRow(geneticTestResult, true);
}
flowLayoutPanel1.Controls.Add(toAdd);
DoScroll(ScrollEnum.Grow);
}
/**************************************************************************************************/
private void LoadGeneticTestResults(string patient_unitnum, int relativeID, int instanceId)
{
using (SqlConnection connection = new SqlConnection(BCDB2.Instance.getConnectionString()))
{
connection.Open();
SqlCommand cmdProcedure = new SqlCommand("sp_3_LoadgeneticTestResults", connection);
cmdProcedure.CommandType = CommandType.StoredProcedure;
cmdProcedure.Parameters.Add("@unitnum", SqlDbType.NVarChar);
cmdProcedure.Parameters["@unitnum"].Value = patient_unitnum;
cmdProcedure.Parameters.Add("@apptid", SqlDbType.Int);
cmdProcedure.Parameters["@apptid"].Value = owningPMH.RelativeOwningPMH.owningFHx.proband.apptid;
cmdProcedure.Parameters.Add("@relId", SqlDbType.NVarChar);
cmdProcedure.Parameters["@relId"].Value = relativeID;
cmdProcedure.Parameters.Add("@instanceId", SqlDbType.Int);
cmdProcedure.Parameters["@instanceId"].Value = instanceID;
try
{
SqlDataReader reader = cmdProcedure.ExecuteReader(CommandBehavior.CloseConnection);
if (reader != null)
{
while (reader.Read())
{
GeneticTestResult geneticTestResult = new GeneticTestResult(this);
for (int i = 0; i < reader.FieldCount; i++)
{
if (reader.IsDBNull(i) == false)
{
foreach (FieldInfo fi in geneticTestResult.GetType().GetFields(BindingFlags.Instance | BindingFlags.Public))
{
string name = fi.Name;
if (name == reader.GetName(i))
{
SetFieldInfoValue(fi, reader.GetValue(i), geneticTestResult);
break;
}
}
}
}
geneticTestResult.HraState = States.Ready;
GeneticTestResults.Add(geneticTestResult);
}
reader.Close();
}
}
catch (Exception ex)
{
Logger.Instance.WriteToLog(ex.ToString());
}
}
}
private void FillDataFromTestResult(GeneticTestResult geneticTestResult)
{
if (geneticTestResult != null)
{
if (this.InvokeRequired)
{
FillDataCallback fdc = new FillDataCallback(FillDataFromTestResult);
object[] args = new object[1];
args[0] = geneticTestResult;
this.Invoke(fdc, args);
}
else
{
if (!string.IsNullOrEmpty(geneticTestResult.geneName))
{
geneNameComboBox.Text = geneticTestResult.geneName;
geneNameTextBox.Text = geneticTestResult.geneName;
}
else
{
geneNameTextBox.ReadOnly = false;
}
mutationNameComboBox.Text = geneticTestResult.mutationName;
mutationAAComboBox.Text = geneticTestResult.mutationAA;
if (geneticTestResult.resultSignificance != null)
{
if (resultSignificanceComboBox.Items.Contains(geneticTestResult.resultSignificance) == false)
{
resultSignificanceComboBox.Items.Add(geneticTestResult.resultSignificance);
}
}
resultSignificanceComboBox.Text = geneticTestResult.resultSignificance;
allelicStateComboBox.Text = geneticTestResult.allelicState;
commentsTextBox.Text = geneticTestResult.comments;
var selection = SessionManager.Instance.MetaData.Mutations
.Where(m =>
((MutationObject)m).geneName == geneticTestResult.geneName &&
((MutationObject)m).mutationDNA == geneticTestResult.mutationName);
string lkpresultSignificance = selection.Select(m => ((MutationObject)m).significance).FirstOrDefault();
if (lkpresultSignificance != geneticTestResult.resultSignificance)
{
//BD - VariantSerive
//label1.Visible = true;
}
else
{
label1.Visible = false;
}
}
}
}
public GeneticTestingResultRow(GeneticTestResult geneticTestResult, bool canDelete)
{
this.geneticTestResult = geneticTestResult;
this.geneticTestResult.AddHandlersWithLoad(TestResultChanged, null, null);
InitializeComponent();
updateUI();
UIUtils.fillComboBoxFromLookups(resultSignificanceComboBox, "tblRiskGeneticTest", "resultSignificance", true);
List<String> geneList = SessionManager.Instance.MetaData.GeneticTests.GetGenesInPanel(geneticTestResult.owningGeneticTest.panelID);
UIUtils.fillComboBoxFromList(geneNameComboBox,geneList,false);
FillDataFromTestResult(geneticTestResult);
//deleteButton.Visible = canDelete;
geneNameComboBox.Visible = canDelete;
geneNameTextBox.Visible = !canDelete;
populateMutationComboBoxes();
initialized = true;
}
private void FillDataFromTestResult(GeneticTestResult geneticTestResult)
{
if (geneticTestResult != null)
{
if (this.InvokeRequired)
{
FillDataCallback fdc = new FillDataCallback(FillDataFromTestResult);
object[] args = new object[1];
args[0] = geneticTestResult;
this.Invoke(fdc, args);
}
else
{
allelicStateComboBox.Text = geneticTestResult.allelicState;
commentsTextBox.Text = geneticTestResult.comments;
ASOInfoTextBox.Text = geneticTestResult.GetASOSummary();
ASOResultComboBox.Text = geneticTestResult.ASOResult;
}
}
}
