/// <summary>
/// Estimates the weights of the PWM that's behind a Block pattern.
/// </summary>
/// <exception cref="System.ArgumentException">
/// Thrown when sequences length are not equal</exception>
/// <param name="sequenceList"> List of aligned sequences. </param>
/// <param name="background"> Histogram with base counts of the background
/// sequences. Can be null. In that case all frequencies are set equally.</param>
private void Estimate
(SequenceList sequenceList, HistogramSymbol background)
{
int length = sequenceList.MinLength();
if (sequenceList.MaxLength() != length)
throw new ArgumentException
("Sequences must be of equal length!");
if (background == null)
{
background = new HistogramSymbol();
foreach (Symbol sym in PWMalphabet)
background.Add(sym);
}
base.Init(length);
base.Estimate(sequenceList, 1, background);
}
