コード例 #1
0
ファイル: ViterbiImpl.cs プロジェクト: jeeshnair/compbio
        /// <summary>
        /// Executes Viterbi in a loop , every loop begins with new updated parameters
        /// </summary>
        public List <ViterbiResult> ExecuteViterbiAndTrain(int executionCount)
        {
            var resultsCollection = new List <ViterbiResult>();

            Stopwatch timer = new Stopwatch();

            timer.Restart();
            for (int i = 1; i <= executionCount; i++)
            {
                ViterbiResult result = FindViterbiProbabilityScoreAndPath();
                resultsCollection.Add(result);
                this.parameters.UpdateParameters(result);
            }
            timer.Stop();
            Console.WriteLine("Timetaken: {0}", timer.ElapsedMilliseconds);

            return(resultsCollection);
        }
コード例 #2
0
 /// <summary>
 /// Updates parameters given the viterbi result.
 /// </summary>
 public abstract void UpdateParameters(ViterbiResult result);
コード例 #3
0
ファイル: ViterbiImpl.cs プロジェクト: jeeshnair/compbio
        /// <summary>
        /// Takes Viterbi matrix element corresponding to maximum probability and maximum probability and computes
        /// a)StateRepresentation( FFFLLLFFFL as in dice roll example )
        /// b)All the sub sequences an starting indexes ending at all the states in the model.
        /// c)Probability score.
        /// </summary>
        ViterbiResult ViterbiTraceback(ViterbiMatrixElement traceBackProbabilityElement, double traceBackProbability)
        {
            var stateSequences = new Dictionary <int, List <ViterbiStateSequence> >();
            var statePath      = new StringBuilder();
            var subSequence    = new StringBuilder[this.parameters.StateIndices.Count];
            var startIndex     = new int[this.parameters.StateIndices.Count];

            // Loop till we reach end of traceback list.
            while (traceBackProbabilityElement != null)
            {
                // Add to state identifiers , we will reverse it at the end.
                statePath.Append(traceBackProbabilityElement.StateIdentifier);
                foreach (KeyValuePair <int, char> item in this.parameters.StateIndices)
                {
                    if (!stateSequences.ContainsKey(item.Key))
                    {
                        stateSequences[item.Key] = new List <ViterbiStateSequence>();
                        subSequence[item.Key]    = new StringBuilder();
                    }

                    if (traceBackProbabilityElement.StateIdentifier == item.Value)
                    {
                        // Start constructing subsequences at a given state. Again , we will reverse it at the end to align with input.
                        // Genomic indexes are 1 based. Increment the zero based index to reflect this convention.
                        startIndex[item.Key] = traceBackProbabilityElement.EmissionValueIndex + 1;;
                        subSequence[item.Key].Append(traceBackProbabilityElement.EmissionValue);
                    }
                    else
                    {
                        // Add to subsequence list per state once we are at the end of subsequence ( when state corresponding to matrix element is different )
                        if (subSequence[item.Key].Length > 0)
                        {
                            stateSequences[item.Key].Add(
                                new ViterbiStateSequence
                            {
                                Index         = startIndex[item.Key],
                                StateSequence = new string(subSequence[item.Key].ToString().ToCharArray().Reverse().ToArray())
                            });

                            //Reset the index and sequence variable
                            startIndex[item.Key] = 0;
                            subSequence[item.Key].Clear();
                        }
                    }

                    // If we are going to reach end of traceback then add the current calculated subsequence.
                    if (traceBackProbabilityElement.ContributingPredecessor == null &&
                        subSequence[item.Key].Length > 0)
                    {
                        stateSequences[item.Key].Add(
                            new ViterbiStateSequence
                        {
                            Index         = startIndex[item.Key],
                            StateSequence = new string(subSequence[item.Key].ToString().ToCharArray().Reverse().ToArray())
                        });
                    }
                }

                traceBackProbabilityElement = traceBackProbabilityElement.ContributingPredecessor;
            }

            // Construct the result.
            var result = new ViterbiResult()
            {
                ProbabilityScore             = traceBackProbability,
                StateTransitionRepresentaton = new string(statePath.ToString().ToCharArray().Reverse().ToArray()),
                ParametersUsed = this.parameters.Clone()
            };

            // Add all the state subsequences.
            result.StateSequences = stateSequences;

            return(result);
        }