private void findPathwayToolStripMenuItem_Click(object sender, EventArgs e) { if (CompleteScreening == null) return; FormForNameRequest FormForRequest = new FormForNameRequest(); if (FormForRequest.ShowDialog() != System.Windows.Forms.DialogResult.OK) return; int NumberOfPlates = CompleteScreening.ListPlatesActive.Count; FormForKeggGene KeggWin = new FormForKeggGene(); KEGG ServKegg = new KEGG(); string[] intersection_gene_pathways = new string[1]; string[] Pathways = { FormForRequest.textBoxForName.Text }; intersection_gene_pathways = ServKegg.get_genes_by_pathway("path:" + Pathways[0]); if ((Pathways == null) || (Pathways.Length == 0)) { MessageBox.Show("No pathway founded !", "Warning", MessageBoxButtons.OK, MessageBoxIcon.Exclamation); return; } string[] fg_list = { "black" }; string[] bg_list = { "orange" }; string pathway_map_html = ""; // KEGG ServKegg = new KEGG(); string[] ListGenesinPathway = ServKegg.get_genes_by_pathway("path:" + Pathways[0]); if (ListGenesinPathway.Length == 0) { return; } double[] ListValues = new double[ListGenesinPathway.Length]; int IDxGeneOfInterest = 0; foreach (cPlate CurrentPlate in CompleteScreening.ListPlatesActive) { foreach (cWell CurrentWell in CurrentPlate.ListActiveWells) { string CurrentLID = "hsa:" + (int)CurrentWell.LocusID; for (int IdxGene = 0; IdxGene < ListGenesinPathway.Length; IdxGene++) { if (CurrentLID == intersection_gene_pathways[0]) IDxGeneOfInterest = IdxGene; if (CurrentLID == ListGenesinPathway[IdxGene]) { ListValues[IdxGene] = CurrentWell.ListDescriptors[CompleteScreening.ListDescriptors.CurrentSelectedDescriptor].GetValue(); break; } } } } bg_list = new string[ListGenesinPathway.Length]; fg_list = new string[ListGenesinPathway.Length]; double MinValue = ListValues.Min(); double MaxValue = ListValues.Max(); for (int IdxCol = 0; IdxCol < bg_list.Length; IdxCol++) { int ConvertedValue = (int)((((CompleteScreening.GlobalInfo.LUTs.LUT_GREEN_TO_RED[0].Length - 1) * (ListValues[IdxCol] - MinValue)) / (MaxValue - MinValue))); Color Coul = Color.FromArgb(CompleteScreening.GlobalInfo.LUTs.LUT_GREEN_TO_RED[0][ConvertedValue], CompleteScreening.GlobalInfo.LUTs.LUT_GREEN_TO_RED[1][ConvertedValue], CompleteScreening.GlobalInfo.LUTs.LUT_GREEN_TO_RED[2][ConvertedValue]); if (IdxCol == IDxGeneOfInterest) fg_list[IdxCol] = "white"; else fg_list[IdxCol] = "#000000"; bg_list[IdxCol] = "#" + Coul.Name.Remove(0, 2); } // foreach (string item in ListP.listBoxPathways.SelectedItems) { pathway_map_html = ServKegg.get_html_of_colored_pathway_by_objects(Pathways[0], ListGenesinPathway, fg_list, bg_list); } pathway_map_html = ServKegg.get_html_of_colored_pathway_by_objects((string)(Pathways[0]), intersection_gene_pathways, fg_list, bg_list); // FormForKegg KeggWin = new FormForKegg(); if (pathway_map_html.Length == 0) return; // //KeggWin.Show(); //ListP.listBoxPathways.MouseDoubleClick += new MouseEventHandler(listBox1_MouseDoubleClick); KeggWin.webBrowser.Navigate(pathway_map_html); KeggWin.Show(); }
void DisplayPathways(object sender, EventArgs e) { if (LocusID == -1) return; FormForKeggGene KeggWin = new FormForKeggGene(); KEGG ServKegg = new KEGG(); string[] intersection_gene_pathways = new string[1]; intersection_gene_pathways[0] = "hsa:" + LocusID; string[] Pathways = ServKegg.get_pathways_by_genes(intersection_gene_pathways); if ((Pathways == null) || (Pathways.Length == 0)) { MessageBox.Show("No pathway founded !", "Warning", MessageBoxButtons.OK, MessageBoxIcon.Exclamation); return; } string GenInfo = ServKegg.bget(intersection_gene_pathways[0]); // FormForPathway PathwaysGenes = new FormForPathway(); KeggWin.richTextBox.Text = GenInfo; KeggWin.Text = "Gene Infos"; //PathwaysGenes.Show(); ListP = new FormForPathway(); ListP.listBoxPathways.DataSource = Pathways; ListP.Text = this.Name; ListP.Show(); //foreach (string item in Pathways) //{ // string PathwayInfo = ServKegg.bget(item); // FormPathwaysGenes PathwaysGenes = new FormPathwaysGenes(); // PathwaysGenes.richTextBox1.Text = PathwayInfo; // PathwaysGenes.Text = "Pathways Infos"; // PathwaysGenes.Show(); //} string[] fg_list = { "black" }; string[] bg_list = { "orange" }; // string[] intersection_gene_pathways = new string[1]; // intersection_gene_pathways[0] = "hsa:" + LocusID; string pathway_map_html = ""; // KEGG ServKegg = new KEGG(); pathway_map_html = ServKegg.get_html_of_colored_pathway_by_objects((string)(ListP.listBoxPathways.SelectedItem), intersection_gene_pathways, fg_list, bg_list); // FormForKegg KeggWin = new FormForKegg(); if (pathway_map_html.Length == 0) return; // //KeggWin.Show(); ListP.listBoxPathways.MouseDoubleClick += new MouseEventHandler(listBox1_MouseDoubleClick); KeggWin.webBrowser.Navigate(pathway_map_html); KeggWin.Show(); }
//void DisplayPathways(object sender, EventArgs e) //{ // if (LocusID == -1) return; // FormForKeggGene KeggWin = new FormForKeggGene(); // KEGG ServKegg = new KEGG(); // string[] intersection_gene_pathways = new string[1]; // intersection_gene_pathways[0] = "hsa:" + LocusID; // string[] Pathways = ServKegg.get_pathways_by_genes(intersection_gene_pathways); // if ((Pathways == null) || (Pathways.Length == 0)) // { // MessageBox.Show("No pathway founded !", "Warning", MessageBoxButtons.OK, MessageBoxIcon.Exclamation); // return; // } // string GenInfo = ServKegg.bget(intersection_gene_pathways[0]); // // FormForPathway PathwaysGenes = new FormForPathway(); // KeggWin.richTextBox.Text = GenInfo; // KeggWin.Text = "Gene Infos"; // //PathwaysGenes.Show(); // ListP = new FormForPathway(); // ListP.listBoxPathways.DataSource = Pathways; // ListP.Text = this.Name; // ListP.Show(); // //foreach (string item in Pathways) // //{ // // string PathwayInfo = ServKegg.bget(item); // // FormPathwaysGenes PathwaysGenes = new FormPathwaysGenes(); // // PathwaysGenes.richTextBox1.Text = PathwayInfo; // // PathwaysGenes.Text = "Pathways Infos"; // // PathwaysGenes.Show(); // //} // string[] fg_list = { "black" }; // string[] bg_list = { "orange" }; // // string[] intersection_gene_pathways = new string[1]; // // intersection_gene_pathways[0] = "hsa:" + LocusID; // string pathway_map_html = ""; // // KEGG ServKegg = new KEGG(); // pathway_map_html = ServKegg.get_html_of_colored_pathway_by_objects((string)(ListP.listBoxPathways.SelectedItem), intersection_gene_pathways, fg_list, bg_list); // // FormForKegg KeggWin = new FormForKegg(); // if (pathway_map_html.Length == 0) return; // // // //KeggWin.Show(); // ListP.listBoxPathways.MouseDoubleClick += new MouseEventHandler(listBox1_MouseDoubleClick); // KeggWin.webBrowser.Navigate(pathway_map_html); // KeggWin.Show(); //} void DisplayPathways(object sender, EventArgs e) { object ValObj = this.ListProperties.FindValueByName("Locus ID"); if (ValObj == null) return; int LocusID = (int)ValObj; List<string> Pathways2 = null; try { Pathways2 = HCSAnalyzer.HCSAnalyzer.Find_Pathways(LocusID); //appel de la function static je ne sais pas pourquoi elle doit etre static… } catch (Exception) { MessageBox.Show("No pathway founded !", "Warning", MessageBoxButtons.OK, MessageBoxIcon.Exclamation); return; } if (Pathways2.Count > 0) { string getvars2 = "/get/hsa:" + LocusID; HttpWebRequest req2 = WebRequest.Create(string.Format("http://rest.kegg.jp" + getvars2)) as HttpWebRequest; req2.Method = "GET"; HttpWebResponse response = req2.GetResponse() as HttpWebResponse; StreamReader reader2 = new StreamReader(response.GetResponseStream()); string GenInfo = reader2.ReadToEnd(); reader2.Close(); foreach (string item in Pathways2) { FormForKeggGene KeggWin = new FormForKeggGene(); KeggWin.webBrowser.Navigate("http://www.kegg.jp/kegg-bin/show_pathway?" + item + "/default%3dpink/" + "hsa:" + LocusID + "%09,blue"); KeggWin.richTextBox.Text = GenInfo; KeggWin.Text = "Gene Infos"; KeggWin.Show(); } response.Close(); } else { MessageBox.Show("No pathway founded !", "Warning", MessageBoxButtons.OK, MessageBoxIcon.Exclamation); } }