コード例 #1
0
        //wrapper should now handle all throwing and catching..
        protected override void ProgramExecution()
        {
            var optionsUsed = _appOptionParser.ParsingResult.OptionsUsed;

            var doNotPassToSubprocess = new List <string>()
            {
                "outFolder", "numProcesses", "exePath", "intermediateDir", "multiprocess", "chromosomes"
            };

            var cmdLineList = MultiProcessHelpers.GetCommandLineWithoutIgnoredArguments(optionsUsed, doNotPassToSubprocess);


            var refNameMapping = new Dictionary <string, int>();

            using (var bamReader = new BamReader(_options.InputBam))
            {
                var chroms = bamReader.GetReferenceNames();
                foreach (var referenceName in chroms)
                {
                    if (_options.Chromosomes != null && !_options.Chromosomes.ToList().Contains(referenceName))
                    {
                        continue;
                    }
                    refNameMapping.Add(referenceName, bamReader.GetReferenceIndex(referenceName));
                }
            }

            var taskManager     = new CliTaskManager(_options.NumProcesses);
            var geminiProcessor = new GeminiMultiProcessor(_options, new CliTaskCreator());

            var samtoolsWrapper = new SamtoolsWrapper(_options.GeminiOptions.SamtoolsPath, _options.GeminiOptions.IsWeirdSamtools);

            geminiProcessor.Execute(taskManager, refNameMapping, cmdLineList, samtoolsWrapper);
        }
コード例 #2
0
        private List <string> ExecuteChromosomeJobs(Dictionary <string, int> chromRefIds,
                                                    string outMultiPath, List <string> taskDirectories)
        {
            var orderedChroms = MultiProcessHelpers.GetOrderedChromosomes(chromRefIds).ToList();
            ConcurrentQueue <string> input = new ConcurrentQueue <string>(orderedChroms);

            Stopwatch stopwatch = new Stopwatch();

            stopwatch.Start();

            var tasks      = new List <Task>();
            var pathsArray = new string[chromRefIds.Max(x => x.Value) + 1];

            using (var concurrencySemaphore = new SemaphoreSlim(_options.NumProcesses))
            {
                foreach (var chrom in orderedChroms)
                {
                    {
                        var options = new GeminiMultiOptions()
                        {
                            StitcherOptions       = (_options.StitcherOptions.DeepCopy()),
                            GeminiSampleOptions   = (_options.GeminiSampleOptions.DeepCopy()),
                            IndelFilteringOptions =
                                (_options.IndelFilteringOptions.DeepCopy()),
                            RealignmentAssessmentOptions =
                                (_options.RealignmentAssessmentOptions.DeepCopy()),
                            RealignmentOptions = (_options.RealignmentOptions.DeepCopy()),

                            GeminiOptions   = (_options.GeminiOptions.DeepCopy()),
                            InputBam        = _options.InputBam,
                            OutputDirectory = _options.OutputDirectory
                        };


                        Console.WriteLine($"Waiting to launch job for chrom {chrom}");
                        Console.WriteLine($"Launching job for chrom {chrom}");
                        concurrencySemaphore.Wait();
                        tasks.Add(Task.Factory.StartNew(() =>
                        {
                            try
                            {
                                pathsArray[chromRefIds[chrom]] = ProcessChromosome(chromRefIds, outMultiPath, taskDirectories, chrom, options);
                            }
                            finally
                            {
                                concurrencySemaphore.Release();
                            }
                        }));
                    }
                }

                Logger.WriteToLog("Launched all tasks.");
                Task.WaitAll(tasks.ToArray());

                return(pathsArray.Where(x => x != null).ToList());
            }
        }
コード例 #3
0
        private List <string> ExecuteChromosomeJobs(ICliTaskManager cliTaskManager, Dictionary <string, int> chromRefIds, List <string> cmdLineList,
                                                    string outMultiPath, string taskLogDir, string exePath, List <string> taskDirectories)
        {
            var tasks = new List <ICliTask>();
            var paths = new List <string>();

            //var loggers = new List<Illumina.CG.Common.Logging.Logger>();

            foreach (var chrom in MultiProcessHelpers.GetOrderedChromosomes(chromRefIds))
            {
                var outdir = Path.Combine(outMultiPath, chrom);
                //var logger = new Illumina.CG.Common.Logging.Logger(taskLogDir, $"GeminiTaskLog_{chrom}.txt");
                //loggers.Add(logger);
                var task = _taskCreator.GetCliTask(cmdLineList.ToArray(), chrom, exePath, outdir, chromRefIds[chrom]);
                tasks.Add(task);
                paths.Add(Path.Combine(outdir, "merged.bam.sorted.bam"));
                taskDirectories.Add(outdir);
            }

            cliTaskManager.Process(tasks);

            foreach (var task in tasks)
            {
                Logger.WriteToLog($"Completed task {task.Name} with exit code {task.ExitCode}.");
            }

            if (tasks.Any(x => x.ExitCode != 0))
            {
                foreach (var failedTask in tasks.Where(x => x.ExitCode != 0))
                {
                    Logger.WriteWarningToLog($"Processing failed for {failedTask.Name}. See error log for details.");
                }

                throw new Exception($"Application failed: {tasks.Count(x => x.ExitCode != 0)} tasks failed.");
            }

            Logger.WriteToLog($"Completed {tasks.Count} tasks.");
            return(paths);
            //try
            //{
            //    foreach (var logger in loggers)
            //    {
            //        logger.Dispose();
            //    }
            //}
            //catch (Exception e)
            //{
            //    Logger.WriteExceptionToLog(
            //        new Exception($"Error encountered during logging cleanup step (after individual analysis completion).", e));
            //}
        }