/// <summary>
/// worker_RunWorkerCompleted
/// </summary>
/// <param name="sender"></param>
/// <param name="e"></param>
private void worker_RunWorkerCompleted(object sender, RunWorkerCompletedEventArgs e)
{
// new score calculation
double newScore = ORF.CPBcalculator(optimizedORF);
//new orf to display
textBox.Text = newScore.ToString();
optimizedORF.Insert(0, textBox.Text);
Data.Rows.Add(optimizedORF.ToArray());
OptimizationDataGrid.ItemsSource = Data.DefaultView;
SaveToFASTAButton.IsEnabled = true;
//max score Textbox update
if (MaximalizeRadioButton.IsChecked == true)
{
maxScores.Add(newScore);
BestMaxCPBscoreTextBox.Text = maxScores.Max().ToString();
}
//min score Textbox update
if (MinimalizeRadioButton.IsChecked == true)
{
minScores.Add(newScore);
BestMinCPBscoreTextBox.Text = minScores.Min().ToString();
}
NcScoreOptimizedTextBox.Text = ORF.NcCalculator(optimizedORF, ORF.aminoAcidCounts).ToString();
}
/// <summary>
/// Method for calculating and displaying
/// </summary>
/// <param name="orf"></param>
/// <param name="amino"></param>
private void CalculateAndDisplayORF(List <string> orf, List <string> amino)
{
Data = new DataTable();
int columnIdx = 0;
Data.Columns.Add(new DataColumn("CPB"));
foreach (var k in ORF.aminoORFseq)
{
Data.Columns.Add(new DataColumn(columnIdx.ToString()));
columnIdx++;
}
// CPBcalculator method initialization
try
{
OriginalCPBscoreTextBox.Text = ORF.CPBcalculator(ORF.orfSeq).ToString();
// datagrid filling
ORF.aminoORFseq.Insert(0, "");
ORF.orfSeq.Insert(0, OriginalCPBscoreTextBox.Text);
Data.Rows.Add(ORF.aminoORFseq.ToArray());
Data.Rows.Add(ORF.orfSeq.ToArray());
ORF.aminoORFseq.RemoveAt(0);
ORF.orfSeq.RemoveAt(0);
OptimizationDataGrid.ItemsSource = Data.DefaultView;
GeneticCode.UploadGeneticCode();
ORF.aminoAcidCounts = ORF.aminoORFseq.GroupBy(i => i)
.ToDictionary(i => i.Key, i => i.Count());
NcScoreTextBox.Text = ORF.NcCalculator(ORF.orfSeq, ORF.aminoAcidCounts).ToString();
}
catch
{
string message = "Something went wrong. Please verify your FASTA file for incorrect codons or check your ranking.";
ModernDialog.ShowMessage(message.ToString(), "Error", MessageBoxButton.OK);
}
}
