public static async IAsyncEnumerable <MedicationInteractionPair> ParseDrugInteractionsAsync(string jstring)
{
//var interactionList = new List<MedicationInteractionPair>();
JObject j = new JObject();
int tokenCount = 0;
int fullInteractiveTypeCount = 0;
int interactionPairCount = 0;
var minConceptTokenList = new List <JToken>();
var urlTokenList = new List <JToken>();
j = JObject.Parse(jstring);
try
{
tokenCount = j["fullInteractionTypeGroup"].Children()["fullInteractionType"].Children()["minConcept"].ToList().Count();
fullInteractiveTypeCount = j["fullInteractionTypeGroup"].Children()["fullInteractionType"].ToList().Count();
}
catch (NullReferenceException)
{
tokenCount = 0;
fullInteractiveTypeCount = 0;
interactionPairCount = 0;
}
for (int f = 0; f < fullInteractiveTypeCount; f++)
{
interactionPairCount = j["fullInteractionTypeGroup"][f]["fullInteractionType"].Children()["interactionPair"].ToList().Count();
for (int i = 0; i < interactionPairCount; i++)
{
var interaction = new MedicationInteractionPair()
{
InteractionId = Guid.NewGuid()
};
interaction.Comment = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["comment"].ToString();
interaction.MedicationPair = (new MedicationInteractionPair.MedicationInteractionViewModel()
{
DisplayName = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["minConcept"][0]["name"].ToString(), RxCui = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["minConcept"][0]["rxcui"].ToString()
}, new MedicationInteractionPair.MedicationInteractionViewModel()
{
DisplayName = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["minConcept"][1]["name"].ToString(), RxCui = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["minConcept"][1]["rxcui"].ToString()
});
//MinConcept also contains the RxCuis, which can be used to .Join these with the MedDTO object thing
//interactionList.Add(interaction);
var interactionConceptCount = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"].Children()["interactionConcept"].ToList().Count();
string PATTERN = @"interaction.(?:(?!\.).)*";
var m = Regex.Matches(interaction.Comment, PATTERN);
// for (int p = 0; p < interactionConceptCount; p++)
// {
// var detail = new MedicationInteractionPair.InteractionDetail();
// detail.InteractionAssertion = char.ToUpper(m[p].Groups[0].Value[0]) + m[p].Groups[0].Value.Substring(1);
// detail.Description = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"][p]["description"].ToString();
// detail.Severity = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"][p]["severity"].ToString();
// detail.LinkTupList = new List<(string, Uri)>(j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"][p]["interactionConcept"].Children()["minConceptItem"]["name"].ToList()
// .Select(x => x.ToString().ToUpper())
// .Zip(j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"][p]["interactionConcept"].Children()["sourceConceptItem"]["url"].ToList()
// .Select(v => new Uri(v.ToString().Equals("NA")
// ? "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422823/"
// : v.ToString()))));
// interaction.DrugInteractionDetails.Add(detail);
// }
var option = new ParallelOptions();
Parallel.For(0, interactionConceptCount, (p, state) =>
{
var detail = new MedicationInteractionPair.InteractionDetail();
detail.InteractionAssertion = char.ToUpper(m[p].Groups[0].Value[0]) + m[p].Groups[0].Value.Substring(1);
detail.Description = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"][p]["description"].ToString();
detail.Severity = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"][p]["severity"].ToString();
detail.LinkTupList = new List <(string, Uri)>(j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"][p]["interactionConcept"].Children()["minConceptItem"]["name"].ToList()
.Select(x => x.ToString().ToUpper())
.Zip(j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"][p]["interactionConcept"].Children()["sourceConceptItem"]["url"].ToList()
.Select(v => new Uri(v.ToString().Equals("NA")
? "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422823/"
: v.ToString()))));
interaction.DrugInteractionDetails.Add(detail);
});
public void ParseDrugInteractions(string jstring)
{
var interactionList = new List <MedicationInteractionPair>();
JObject j = new JObject();
int tokenCount = 0;
int fullInteractiveTypeCount = 0;
int interactionPairCount = 0;
var minConceptTokenList = new List <JToken>();
var urlTokenList = new List <JToken>();
j = JObject.Parse(jstring);
try
{
tokenCount = j["fullInteractionTypeGroup"].Children()["fullInteractionType"].Children()["minConcept"].ToList().Count();
fullInteractiveTypeCount = j["fullInteractionTypeGroup"].Children()["fullInteractionType"].ToList().Count();
}
catch (NullReferenceException)
{
tokenCount = 0;
fullInteractiveTypeCount = 0;
interactionPairCount = 0;
}
for (int f = 0; f < fullInteractiveTypeCount; f++)
{
interactionPairCount = j["fullInteractionTypeGroup"][f]["fullInteractionType"].Children()["interactionPair"].ToList().Count();
for (int i = 0; i < interactionPairCount; i++)
{
var interaction = new MedicationInteractionPair()
{
InteractionId = Guid.NewGuid()
};
interaction.Comment = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["comment"].ToString();
interaction.MedicationPair = (new MedicationInteractionPair.MedicationInteractionViewModel()
{
DisplayName = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["minConcept"][0]["name"].ToString(), RxCui = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["minConcept"][0]["rxcui"].ToString()
}, new MedicationInteractionPair.MedicationInteractionViewModel()
{
DisplayName = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["minConcept"][1]["name"].ToString(), RxCui = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["minConcept"][1]["rxcui"].ToString()
});
//MinConcept also contains the RxCuis, which can be used to .Join these with the MedDTO object thing
interactionList.Add(interaction);
var interactionConceptCount = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"].Children()["interactionConcept"].ToList().Count();
string PATTERN = @"interaction.(?:(?!\.).)*";
var m = Regex.Matches(interaction.Comment, PATTERN);
//int parseHelper = 5;
for (int p = 0; p < interactionConceptCount; p++)
{
var detail = new MedicationInteractionPair.InteractionDetail();
detail.InteractionAssertion = char.ToUpper(m[p].Groups[0].Value[0]) + m[p].Groups[0].Value.Substring(1);
detail.Description = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"][p]["description"].ToString();
detail.Severity = j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"][p]["severity"].ToString();
detail.LinkTupList = new List <(string, Uri)>(j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"][p]["interactionConcept"].Children()["minConceptItem"]["name"].ToList()
.Select(x => x.ToString().ToUpper())
.Zip(j["fullInteractionTypeGroup"][f]["fullInteractionType"][i]["interactionPair"][p]["interactionConcept"].Children()["sourceConceptItem"]["url"].ToList()
.Select(v => new Uri(v.ToString().Equals("NA")
? "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422823/"
: v.ToString()))));
//detail.InteractionAssertion = (interaction.Comment.Substring(m.Index + 4)[0])+ interaction.Comment.Substring(m.Index + 5)?? "No Details on Source available";
//string[] stringArray = { "Drug1", "Drug2" };
//var splitString = interaction.Comment.Split(stringArray, StringSplitOptions.RemoveEmptyEntries);
//string levelOne = p == 0 ? splitString[3] : splitString[parseHelper];
//var levelTwo = levelOne.Split("and ", 2)[1];
//detail.InteractionAssertion = char.ToUpper(levelTwo[0]) + levelTwo.Substring(1);
//while (p > 0)
//{
// parseHelper = splitString.Count() - 1 > parseHelper ? parseHelper + 2 : 5;
// break;
//}
interaction.DrugInteractionDetails.Add(detail);
}
foreach (var observer in observers)
{
observer.OnNext(interaction);
}
}
if (interactionPairCount == 0)
{
var emptyDrug = new MedicationInteractionPair();
emptyDrug.DrugInteractionDetails.Add(
new MedicationInteractionPair.InteractionDetail()
{
Description = "No Drug-Drug Interactions Found", Severity = "N/A", LinkTupList = new List <(string, Uri)>()
{
("NIH", new Uri(Constants.NLM_INTERACTION_API_URI))
}
});
