コード例 #1
0
        public void Classification_GivenParams_ReturnsCorrectAscvdRiskClassification(GenderIdentity genderIdentity,
                                                                                     int systolic, double hdl, double totalCholesterol, double ldl,
                                                                                     bool diabetic, bool antiHypertensive, bool smoker, bool ascvdPresent, AscvdRiskClassification expected)
        {
            _patient.Gender = Gender.Build(genderIdentity);

            if (diabetic)
            {
                _patient.Comorbidities.Add(ChronicDisease.Diabetes);
            }
            if (antiHypertensive)
            {
                _patient.Comorbidities.Add(ChronicDisease.HypertensionTreated);
            }
            if (smoker)
            {
                _patient.Comorbidities.Add(ChronicDisease.TobaccoSmoker);
            }
            if (ascvdPresent)
            {
                _patient.Comorbidities.Add(ChronicDisease.DiagnosedCardiovascularDisease);
            }

            var ascvdClassification = new AscvdClassification(AscvdParameters.Build(_patient,
                                                                                    BloodPressure.Build(systolic, 75), Quantitative.Serum.CholesterolTotal(totalCholesterol),
                                                                                    Quantitative.Serum.LowDensityLipoprotein(ldl), Quantitative.Serum.HighDensityLipoprotein(hdl)));

            Assert.Equal(expected, ascvdClassification.Classification.TenYearRiskClassification);
        }
コード例 #2
0
 public void Build_GivenTotalCholesterolWithWrongLabtype_ThrowsInvalidEnumArgumentException()
 {
     _totalCholesterol.Type = QuantitativeLabType.AlanineTransaminaseSerum;
     Assert.Throws <InvalidEnumArgumentException>(
         () => AscvdParameters.Build(_patient, _bloodPressure, _totalCholesterol, _ldlCholesterol,
                                     _hdlCholesterol));
 }
コード例 #3
0
 public void Build_GivenNullTotalCholesterol_ThrowsArgumentNullException()
 {
     _totalCholesterol = null;
     Assert.Throws <ArgumentNullException>(
         () => AscvdParameters.Build(_patient, _bloodPressure, _totalCholesterol, _ldlCholesterol,
                                     _hdlCholesterol));
 }
コード例 #4
0
        public void ToString_ReturnsNonEmptyString()
        {
            var riskFactors = new AscvdClassification(AscvdParameters.Build(
                                                          PatientBuilder.Initialize().SetGender(GenderIdentity.Male).BuildWithoutModelValidation(),
                                                          BloodPressure.Build(0, 0), Quantitative.Serum.CholesterolTotal(0),
                                                          Quantitative.Serum.LowDensityLipoprotein(0), Quantitative.Serum.HighDensityLipoprotein(0)));

            Assert.NotEmpty(riskFactors.ToString());
        }
コード例 #5
0
        public void Classfication_GivenParams_ReturnsCorrectListOfRiskFactors()
        {
            _patient.Comorbidities.AddRange(new List <ChronicDisease>
            {
                ChronicDisease.Diabetes,
                ChronicDisease.TobaccoSmoker
            });
            var ascvd = new AscvdClassification(AscvdParameters.Build(_patient, BloodPressure.Build(130, 75),
                                                                      Quantitative.Serum.CholesterolTotal(213), Quantitative.Serum.LowDensityLipoprotein(195),
                                                                      Quantitative.Serum.HighDensityLipoprotein(50)));

            var riskFactors = ascvd.Classification.RiskFactors;

            Assert.Contains(AscvdModifiableRiskFactors.BloodPressureElevated, riskFactors);
            Assert.Contains(AscvdModifiableRiskFactors.TotalCholesterolElevated, riskFactors);
            Assert.Contains(AscvdModifiableRiskFactors.Diabetes, riskFactors);
            Assert.Contains(AscvdModifiableRiskFactors.Smoker, riskFactors);
        }
コード例 #6
0
        public static void Main(string[] args)
        {
            var patient = PatientBuilder
                          .Initialize()
                          .SetDateOfBirth(1952, 3, 31)
                          .SetGender(GenderIdentity.NonBinaryXy)
                          .SetMedicalRecordNumber("1234")
                          .SetName("Joe", "Bob")
                          .SetRace(Race.BlackOrAfricanAmerican)
                          .Build();

            Console.WriteLine($"Meet our patient: {patient}{NewLine}");

            var vitals = VitalSignsBuilder.Initialize()
                         .SetBloodPressure(168, 99, false)
                         .SetOxygenSaturation(96)
                         .SetPulseRate(105)
                         .SetTemperature(101.2)
                         .Build();

            Console.WriteLine($"{patient.Name.First}'s vitals: {vitals}{NewLine}");

            var bp = BloodPressure.Build(100, 66);

            Console.WriteLine($"If {patient.Name.First} used to have good blood pressure, it  was {bp}.{NewLine}");

            var bodyComposition = BodyCompositionBuilder
                                  .Initialize()
                                  .SetHeight(70.9)
                                  .SetHips(40)
                                  .SetWaist(34)
                                  .SetWeight(193)
                                  .Build();

            Console.WriteLine($"Simple body composition measures: {bodyComposition}{NewLine}");

            var bodyCompositionExpanded = BodyCompositionExpandedBuilder
                                          .Initialize()
                                          .SetBodyFatPercentage(16.5)
                                          .SetHeight(bodyComposition.Height.Inches)
                                          .SetHips(bodyComposition.Hips.Inches)
                                          .SetVisceralFat(70)
                                          .SetWaist(bodyComposition.Waist.Inches)
                                          .SetWeight(bodyComposition.Weight.Pounds)
                                          .Build();

            Console.WriteLine($"Expanded body composition measures: {bodyCompositionExpanded}{NewLine}");

            var quantitativeLabChoesterol = Quantitative.Serum.CholesterolTotal(300);

            Console.WriteLine($"Quantitative Lab: {quantitativeLabChoesterol}.{NewLine}");

            var quantitativeLabHdlC = Quantitative.Serum.HighDensityLipoprotein(35);

            Console.WriteLine($"Quantitative Lab: {quantitativeLabHdlC}.{NewLine}");

            var quantitativeLabLdlC = Quantitative.Serum.LowDensityLipoprotein(173);

            Console.WriteLine($"Quantitative Lab: {quantitativeLabLdlC}.{NewLine}");

            var qualitativeLab = Qualitative.HepatitisCAntibody(QualitativeLabResult.Negative);

            Console.WriteLine($"Qualitative Lab: {qualitativeLab.Type}, Result: {qualitativeLab.Result}{NewLine}");

            var cardioRegimen = CardiovascularRegimen.Build(3, 98.5, ExerciseIntensity.Moderate);

            Console.WriteLine($"Cardio regimen: {cardioRegimen}{NewLine}");

            var stretchRegimen = StretchingRegimen.Build(1, 10, ExerciseIntensity.Low);

            Console.WriteLine($"Stretching regimen: {stretchRegimen}{NewLine}");

            var resistanceRegimen = ResistanceRegimenBuilder
                                    .Initialize()
                                    .SetAverageSessionDuration(120)
                                    .SetIntensity(ExerciseIntensity.Moderate)
                                    .SetSecondsRestDurationPerSet(90)
                                    .SetSessionsPerWeek(6)
                                    .ConfirmUpperBodyTrained()
                                    .ConfirmPullingMovementsPerformed()
                                    .ConfirmPushingMovementsPerformed()
                                    .ConfirmRepetitionsToNearFailure()
                                    .Build();

            Console.WriteLine($"Resistance regimen: {resistanceRegimen}{NewLine}");

            var audiogramDataLeft = AudiogramDatasetBuilder
                                    .Initialize()
                                    .Set125HertzDataPoint(10)
                                    .Set250HertzDataPoint(20)
                                    .Set500HertzDataPoint(30)
                                    .Set1000HertzDataPoint(10)
                                    .Set2000HertzDataPoint(25)
                                    .Set3000HertzDataPoint(45)
                                    .Set4000HertzDataPoint(40)
                                    .Set6000HertzDataPoint(50)
                                    .Set8000HertzDataPoint(70)
                                    .Build();

            var audiogramDataRight = AudiogramDatasetBuilder
                                     .Initialize()
                                     .Set125HertzDataPoint(10)
                                     .Set250HertzDataPoint(20)
                                     .Set500HertzDataPoint(30)
                                     .Set1000HertzDataPoint(10)
                                     .Set2000HertzDataPoint(25)
                                     .Set3000HertzDataPoint(45)
                                     .Set4000HertzDataPoint(40)
                                     .Set6000HertzDataPoint(50)
                                     .Set8000HertzDataPoint(90)
                                     .Build();

            var audiogram = Audiogram.Build(audiogramDataLeft, audiogramDataRight);

            Console.WriteLine($"Audiogram{NewLine}{audiogram}{NewLine}");

            var carotidLeft = CarotidUltrasoundResultBuilder
                              .Initialize()
                              .SetIntimaMediaThickeness(0.693)
                              .Build();

            var carotidRight = CarotidUltrasoundResultBuilder
                               .Initialize()
                               .SetIntimaMediaThickeness(0.732)
                               .SetImtGrade(CarotidIntimaMediaThicknessGrade.Mild)
                               .SetPercentStenosisGrade(CarotidPercentStenosisGrade.Nominal)
                               .SetPlaqueCharacter(CarotidPlaqueCharacter.EarlyBuildup)
                               .Build();

            var carotidUs = CarotidUltrasound.Build(carotidLeft, carotidRight);

            Console.WriteLine($"Carotid US{NewLine}{carotidUs}{NewLine}");

            var centralBp = CentralBloodPressureBuilder
                            .Initialize()
                            .SetAugmentedIndex(25)
                            .SetAugmentedPressure(4)
                            .SetCentralSystolicPressure(113)
                            .SetPulsePressure(16)
                            .SetPulseWaveVelocity(7.9)
                            .SetReferenceAge(43)
                            .Build();

            Console.WriteLine($"Central BP: {centralBp}{NewLine}");

            var functionalMovementScreen = FunctionalMovementScreenBuilder
                                           .Initialize()
                                           .SetActiveStraightLegRaise(2, 3)
                                           .SetDeepSquat(3)
                                           .SetHurdleStep(2, 2)
                                           .SetInlineLunge(3, 3)
                                           .SetRotaryStability(2, 2, true)
                                           .SetShoulderMobility(2, false, 2, false)
                                           .SetTrunkStabilityPuhsup(2, false)
                                           .Build();

            Console.WriteLine($"Functional Movement Screen{NewLine}{functionalMovementScreen}{NewLine}");

            var gripStrength = GripStrength.Build(123, 135);

            Console.WriteLine($"Grip strength {gripStrength}{NewLine}");

            var ishiharaSix = IshiharaSixPlateScreenBuilder
                              .Initialize()
                              .SetPlate1(IshiharaAnswerResult.NormalVision)
                              .SetPlate2(IshiharaAnswerResult.ColorVisionDefict)
                              .SetPlate3(IshiharaAnswerResult.NormalVision)
                              .SetPlate4(IshiharaAnswerResult.NormalVision)
                              .SetPlate5(IshiharaAnswerResult.NormalVision)
                              .SetPlate6(IshiharaAnswerResult.ColorVisionDefict)
                              .Build();

            Console.WriteLine("Ishihara Six Plate Screener");
            Console.WriteLine($"{ishiharaSix}{NewLine}");

            var ocularPressure = OccularPressure.Build(15, 13);

            Console.WriteLine($"Ocular pressure: {ocularPressure}{NewLine}");

            var peripheralVision = PeripheralVision.Build(85, 85);

            Console.WriteLine($"Peripheral vision: {peripheralVision}{NewLine}");

            var pushups = Pushups.Build(35);

            Console.WriteLine($"Pushups: {pushups}{NewLine}");

            var sitAndReach = SitAndReach.Build(13);

            Console.WriteLine($"Sit & Reach: {sitAndReach}{NewLine}");

            var situps = Situps.Build(55);

            Console.WriteLine($"Situps: {situps}{NewLine}");

            var spirometry = SpirometryBuilder
                             .Initialize()
                             .SetForcedVitalCapacity(6.3)
                             .SetForcedExpiratoryVolume1Second(5.5)
                             .SetForcedExpiratoryFlow25To75(6.3)
                             .SetForcedExpiratoryTime(7.5)
                             .SetPeakExpiratoryFlow(9.3)
                             .Build();

            Console.WriteLine($"Spirometry: {spirometry}{NewLine}");

            var treadmillStressTest = TreadmillExerciseStressTestBuilder
                                      .Initialize()
                                      .SetMaximumBloodPressure(205, 95)
                                      .SetMaximumHeartRate(183)
                                      .SetProtocol()
                                      .SetResult(TmstResult.Normal)
                                      .SetSupineBloodPressure(133, 82)
                                      .SetSupineHeartRate(66)
                                      .SetTime(11, 33)
                                      .Build();

            Console.WriteLine($"Treadmill: {treadmillStressTest}{NewLine}");

            var visualAcuity = VisualAcuity.Build(20, 20, 20);

            Console.WriteLine($"Visual acuity: {visualAcuity}{NewLine}");

            var predictedMaxHrStd = PredictMaximumHeartRate.Standard(patient.Age);

            Console.WriteLine($"Joes predicted max HR (standard formula): {predictedMaxHrStd} bpm{NewLine}");

            var predictedMaxHrRevisited = PredictMaximumHeartRate.Revisited(patient.Age);

            Console.WriteLine($"Joes predicted max HR (revisted formula): {predictedMaxHrRevisited} bpm{NewLine}");

            var vo2Max = CalculateVo2Max.FromTreadmillStressTest(treadmillStressTest, patient);

            Console.WriteLine($"Joes VO2Max as calculated from his treadmill stress test: {vo2Max}{NewLine}");

            var metsTreadmill = CalculateMetabolicEquivalents.FromTreadmillStressTest(treadmillStressTest, patient);

            Console.WriteLine($"Joes METS as calculated from his treadmill stress test: {metsTreadmill}{NewLine}");

            var metsVo2Max = CalculateMetabolicEquivalents.FromVo2Max(vo2Max);

            Console.WriteLine($"Joes METS as calcualted from his VO2Max: {metsVo2Max}{NewLine}");

            var cardioIniterp = new CardiovascularRegimenClassification(cardioRegimen);

            Console.WriteLine($"Cardio Regimen: {cardioIniterp}{NewLine}");

            var resistanceInterp = new ResistanceRegimenClassification(resistanceRegimen);

            Console.WriteLine($"Resistance Regimen: {resistanceInterp}{NewLine}");

            var stretchingInterp = new StretchingRegimenClassification(stretchRegimen);

            Console.WriteLine($"Stretching Regimen: {stretchingInterp}{NewLine}");

            var audiogramInterpretation = new AudiogramClassification(audiogram);

            Console.WriteLine($"Audiogram Classification: {audiogramInterpretation}{NewLine}");

            var bpInterpretation = new BloodPressureClassification(vitals.BloodPressure);

            Console.WriteLine($"BP Classification: {bpInterpretation}{NewLine}");

            var bodyCompInterp =
                new BodyCompositionClassification(
                    new BodyCompositionClassificationParameters(bodyCompositionExpanded, patient));

            Console.WriteLine($"Body comp: {bodyCompInterp}{NewLine}");

            var bodyCompExpandedInterp =
                new BodyCompositionExpandedClassification(
                    new BodyCompositionExpandedClassificationParameters(bodyCompositionExpanded, patient));

            Console.WriteLine($"Body comp expanded: {bodyCompExpandedInterp}{NewLine}");

            var bmiInterp =
                new BodyMassIndexClassification(new BodyCompositionClassificationParameters(bodyComposition, patient));

            Console.WriteLine($"BMI: {bmiInterp}{NewLine}");

            var carotidUsInterp = new CarotidUltrasoundClassification(carotidUs);

            Console.WriteLine($"Carotid US: {carotidUsInterp}{NewLine}");

            var centralBpInterp =
                new CentralBloodPressureClassification(new CentralBloodPressureParameters(centralBp, patient));

            Console.WriteLine($"Central BP: {centralBpInterp}{NewLine}");

            var fitScoreInterp =
                new FitTreadmillScoreClassification(
                    new TreadmillExerciseStressTestClassificationParameters(treadmillStressTest, patient));

            Console.WriteLine($"FIT Score: {fitScoreInterp}{NewLine}");

            var fmsInterpretation = new FunctionalMovementScreenClassification(functionalMovementScreen);

            Console.WriteLine($"FMS{NewLine}{fmsInterpretation}{NewLine}");

            var gripInterp =
                new GripStrengthClassification(new GripStrengthClassificationParameters(gripStrength, patient));

            Console.WriteLine($"Grip strength: {gripInterp}{NewLine}");

            var hipToWaistInterp =
                new HipToWaistClassification(
                    new BodyCompositionClassificationParameters(bodyCompositionExpanded, patient));

            Console.WriteLine($"Hip to Waist: {hipToWaistInterp}{NewLine}");

            var ishiharaSixInterp = new IshiharaSixPlateClassification(ishiharaSix);

            Console.WriteLine($"Ishihara 6 Plate: {ishiharaSixInterp}{NewLine}");

            var ocularPressureInterp = new OccularPressureClassification(ocularPressure);

            Console.WriteLine($"Ocular Pressure: {ocularPressureInterp}{NewLine}");

            var percentBodyFatInterp =
                new PercentBodyFatClassification(
                    new BodyCompositionExpandedClassificationParameters(bodyCompositionExpanded, patient));

            Console.WriteLine($"Percent BF: {percentBodyFatInterp}{NewLine}");

            var peripheralVisionInterp = new PeripheralVisionClassification(peripheralVision);

            Console.WriteLine($"Peripheral Vision: {peripheralVisionInterp}{NewLine}");

            var pushupsInterp =
                new PushupsClassification(new PushupsClassificationParameters(pushups, patient));

            Console.WriteLine($"Pushups: {pushupsInterp}{NewLine}");

            var qualitativeLabInterp = new QualitativeLabClassification(qualitativeLab);

            Console.WriteLine($"Qualitative Lab: {qualitativeLabInterp}{NewLine}");

            var quantLabInterpTotalChol =
                new QuantitativeLabClassification(
                    new QuantitativeLabClassificationParameters(quantitativeLabChoesterol, patient));

            Console.WriteLine($"Quantitative Lab: {quantLabInterpTotalChol}{NewLine}");

            var quantLabInterpHdlC =
                new QuantitativeLabClassification(
                    new QuantitativeLabClassificationParameters(quantitativeLabHdlC, patient));

            Console.WriteLine($"Quantitative Lab: {quantLabInterpHdlC}{NewLine}");

            var quantLabInterpLdlC =
                new QuantitativeLabClassification(
                    new QuantitativeLabClassificationParameters(quantitativeLabLdlC, patient));

            Console.WriteLine($"Quantitative Lab: {quantLabInterpLdlC}{NewLine}");

            var sitAndReachInterp =
                new SitAndReachClassification(new SitAndReachClassificationParameters(sitAndReach, patient));

            Console.WriteLine($"Sit & Reach: {sitAndReachInterp}{NewLine}");

            var situpsInterp = new SitupsClassification(new SitupsClassificationParameters(situps, patient));

            Console.WriteLine($"Situps: {situpsInterp}{NewLine}");

            var spirometryInterp =
                new SpirometryClassification(
                    new SpirometryClassificationParameters(spirometry, patient, bodyComposition));

            Console.WriteLine($"Spirometry: {spirometryInterp}{NewLine}");

            var visceralFatInterp = new VisceralFatClassification(bodyCompositionExpanded);

            Console.WriteLine($"Visceral fat: {visceralFatInterp}{NewLine}");

            var visualAcuityInterp = new VisualAcuityClassification(visualAcuity);

            Console.WriteLine($"Visual Acuity: {visualAcuityInterp}{NewLine}");

            var vo2MaxInterp =
                new Vo2MaxClassification(new Vo2MaxClassificationParameters(treadmillStressTest, patient));

            Console.WriteLine($"VO2 Max: {vo2MaxInterp}{NewLine}");

            var waistToHeightInterp =
                new WaistToHeightRatioClassification(
                    new BodyCompositionClassificationParameters(bodyComposition, patient));

            Console.WriteLine($"Waist to Height: {waistToHeightInterp}{NewLine}");

            var pooledCohortParams = PooledCohortEquationParametersBuilder.Initialize()
                                     .SetBloodPressure(vitals.BloodPressure)
                                     .SetHdlCholesterol(quantitativeLabHdlC.Result)
                                     .SetTotalCholesterol(quantitativeLabChoesterol.Result)
                                     .SetPatient(patient)
                                     .ConfirmDiabetic()
                                     .ConfirmOnAntiHypertensiveMedication()
                                     .ConfirmSmoker()
                                     .Build();

            var pooledCohortsEquation = new PooledCohortsEquation(pooledCohortParams);

            Console.WriteLine($"ASCVD 10yr-Risk%: {pooledCohortsEquation.Ascvd10YearRiskPercentage}{NewLine}");
            Console.WriteLine($"ASCVD Lifetime Risk%: {pooledCohortsEquation.AscvdLifetimeRiskPercentage}{NewLine}");

            var ascvd10YrInterp = new AscvdClassification(AscvdParameters.Build(patient, vitals.BloodPressure,
                                                                                quantitativeLabChoesterol, quantitativeLabLdlC, quantitativeLabHdlC));

            Console.WriteLine($"ASCVD 10-Year Risk Classification{NewLine}{ascvd10YrInterp.Classification}{NewLine}");
        }