public void TranscribeRnaTest()
{
// Arrange
var dna = new Dna("GATGGAACTTGACTACGTAAATT");
var expectedRna = new Rna("GAUGGAACUUGACUACGUAAAUU");
// Act
var resultRna = dna.TranscribeRna();
// Assert
Assert.That(expectedRna, Is.EqualTo(resultRna));
}
public void ReversedDnaTest()
{
// Arrange
var dna = new Dna("AAAACCCGGT");
var expectedDna = new Dna("ACCGGGTTTT");
// Act
var resultDna = dna.ReverseComplementDna();
// Assert
Assert.That(expectedDna, Is.EqualTo(resultDna));
}
public void HammingDistanceTest()
{
// Arrange
var dna = new Dna("GAGCCTACTAACGGGAT");
var mutatedDna = new Dna("CATCGTAATGACGGCCT");
const int expectedMutationCount = 7;
// Act
var mutationCount = dna.HammingDistance(mutatedDna);
// Assert
Assert.That(expectedMutationCount, Is.EqualTo(mutationCount));
}
public void NucleotidesCountTest()
{
// Arrange
var dna = new Dna("AGCTTTTCATTCTGACTGCAACGGGCAATATGTCTCTGTGTGGATTAAAAAAAGAGTGTCTGATAGCAGC");
var expectedResult = new Dictionary<char, int>
{
{ 'A', 20 }, { 'C', 12 }, { 'G', 17 }, { 'T', 21 }
};
// Act
var actualResult = dna.NucleotidesCount();
// Assert
Assert.That(expectedResult, Is.EqualTo(actualResult));
}
/// <summary>
/// Solves the REVC problem (http://rosalind.info/problems/revc/).
/// </summary>
private static void SolveRevc()
{
var dna = new Dna(File.ReadAllText(@"Data\REVC\rosalind_revc.txt"));
var reverseComplement = dna.ReverseComplementDna();
SaveResult(@"Results\rosalind_revc_results.txt", reverseComplement.Symbols);
}
/// <summary>
/// Solves the RNA problem (http://rosalind.info/problems/rna/).
/// </summary>
private static void SolveRna()
{
var dna = new Dna(File.ReadAllText(@"Data\RNA\rosalind_rna.txt"));
var rna = dna.TranscribeRna();
SaveResult(@"Results\rosalind_rna_results.txt", rna.Symbols);
}
private static void SolveDna()
{
var dna = new Dna(File.ReadAllText(@"Data\DNA\rosalind_dna.txt"));
var nucleotidesCount = dna.NucleotidesCount();
var result = String.Format("{0} {1} {2} {3}", nucleotidesCount['A'],
nucleotidesCount['C'], nucleotidesCount['G'], nucleotidesCount['T']);
SaveResult(@"Results\rosalind_dna_results.txt", result);
}
/// <summary>
/// Solves the HAMM problem (http://rosalind.info/problems/hamm/).
/// </summary>
private static void SolveHamm()
{
var lines = File.ReadAllLines(@"Data\HAMM\rosalind_hamm.txt");
var firstDna = new Dna(lines[0].Trim());
var secondDna = new Dna(lines[1].Trim());
var hammingDistance = firstDna.HammingDistance(secondDna);
SaveResult(@"Results\rosalind_hamm_results.txt", hammingDistance.ToString(CultureInfo.InvariantCulture));
}
public int HammingDistance(Dna dna)
{
return(Symbols.Where((t, i) => t != dna.Symbols[i]).Count());
}
public int HammingDistance(Dna dna)
{
return Symbols.Where((t, i) => t != dna.Symbols[i]).Count();
}
