protected override void Seed(TCRContext context)
{
base.Seed(context);
//if (System.Diagnostics.Debugger.IsAttached == false) // Для отладки / for debugging
// System.Diagnostics.Debugger.Launch();
context.Receptors.RemoveRange(context.Receptors);
context.People.RemoveRange(context.People);
context.VSegments.RemoveRange(context.VSegments);
context.DSegments.RemoveRange(context.DSegments);
context.JSegments.RemoveRange(context.JSegments);
context.SaveChanges();
context.Configuration.AutoDetectChangesEnabled = false;
FillVSegments(context);
FillDSegments(context);
FillJSegments(context);
string[] files = Directory.GetFiles(ConfigurationManager.AppSettings["InitDataPath"], "*.tcr");
for (int i = 0; i < files.Length; ++i)
{
string name = "Person" + (i + 1).ToString();
Person person = new Person {
FirstName = name, MiddleName = name, LastName = name
};
context.People.Add(person);
context.SaveChanges();
FileStream fileStream = new FileStream(files[i], FileMode.Open);
StreamReader reader = new StreamReader(fileStream);
string curStr = null;
reader.ReadLine(); // Пропускаем названия столбцов/ Shifting columns' names
while ((curStr = reader.ReadLine()) != null)
{
string[] fields = curStr.Split('\t');
string nucleoSeq = fields[2];
Receptor receptor = context.Receptors.FirstOrDefault(r => r.NucleoSequence == nucleoSeq);
if (receptor == null)
{
receptor = new Receptor
{
NucleoSequence = fields[2],
AminoSequence = fields[3],
LastVNucleoPos = Convert.ToInt32(fields[7]),
FirstDNucleoPos = Convert.ToInt32(fields[8]),
LastDNucleoPos = Convert.ToInt32(fields[9]),
FirstJNucleoPos = Convert.ToInt32(fields[10]),
VDInsertions = Convert.ToInt32(fields[11]),
DJInsertions = Convert.ToInt32(fields[12]),
TotalInsertions = Convert.ToInt32(fields[13])
};
FillSegments(context, fields, receptor);
context.Receptors.Add(receptor);
context.SaveChanges();
}
context.PersonalReceptors.Add(new PersonalReceptor
{
ReadCount = Convert.ToInt32(fields[0]),
Percentage = Convert.ToDouble(fields[1], new NumberFormatInfo()
{
NumberDecimalSeparator = "."
}),
Receptor = receptor,
Person = person
});
context.SaveChanges();
}
}
}
private static void FillSegments(TCR.Models.TCRContext context, string[] fields, Receptor receptor)
{
string[] alleles = fields[4].Split(new string[] { ", " }, StringSplitOptions.RemoveEmptyEntries);
foreach (string allele in alleles)
{
VSegment segment = context.VSegments.First(s => s.Alleles == allele);
receptor.VSegments.Add(segment);
}
alleles = fields[6].Split(new string[] { ", " }, StringSplitOptions.RemoveEmptyEntries);
foreach (string allele in alleles)
{
DSegment segment = context.DSegments.First(s => s.Alleles == allele);
receptor.DSegments.Add(segment);
}
alleles = fields[5].Split(new string[] { ", " }, StringSplitOptions.RemoveEmptyEntries);
foreach (string allele in alleles)
{
JSegment segment = context.JSegments.First(s => s.Alleles == allele);
receptor.JSegments.Add(segment);
}
}