Esempio n. 1
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        public void ChangeDetails(DateTime?onsetDate, DateTime?resolutionDate, TerminologyMedDra sourceTerminology, string sourceDescription)
        {
            OnsetDate      = onsetDate;
            ResolutionDate = resolutionDate;

            SourceTerminologyMedDra   = sourceTerminology;
            SourceTerminologyMedDraId = sourceTerminology?.Id;

            SourceDescription = sourceDescription;
        }
Esempio n. 2
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        public PatientClinicalEvent(DateTime?onsetDate, DateTime?resolutionDate, TerminologyMedDra sourceTerminology, string sourceDescription)
        {
            PatientClinicalEventGuid = Guid.NewGuid();
            Archived = false;

            OnsetDate      = onsetDate;
            ResolutionDate = resolutionDate;

            if (sourceTerminology != null)
            {
                SourceTerminologyMedDra   = sourceTerminology;
                SourceTerminologyMedDraId = sourceTerminology.Id;
            }

            SourceDescription = sourceDescription;
        }
Esempio n. 3
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        public PatientCondition AddOrUpdatePatientCondition(long id,
                                                            TerminologyMedDra sourceTerm,
                                                            DateTime onsetDate,
                                                            DateTime?outComeDate,
                                                            Outcome outcome,
                                                            TreatmentOutcome treatmentOutcome,
                                                            string caseNumber,
                                                            string comments,
                                                            string conditionSource,
                                                            PatientStatus deceasedStatus)
        {
            PatientCondition patientCondition = null;

            if (id == 0)
            {
                patientCondition = new PatientCondition
                {
                    ConditionSource   = conditionSource,
                    TerminologyMedDra = sourceTerm,
                    OnsetDate         = onsetDate,
                    OutcomeDate       = outComeDate,
                    Outcome           = outcome,
                    TreatmentOutcome  = treatmentOutcome,
                    CaseNumber        = caseNumber,
                    Comments          = comments
                };

                PatientConditions.Add(patientCondition);
            }

            // Has person died
            if (outcome?.Description == "Fatal" && GetCurrentStatus()?.PatientStatus.Description != "Died")
            {
                // set patient status to deceased in patient history
                PatientStatusHistories.Add(new PatientStatusHistory()
                {
                    EffectiveDate = outComeDate ?? DateTime.Now,   //set effective date to  outcome date have set it to  use todays day if null but this will not happen as  autosetToDeceased will only become true when an end date is supplied first
                    Comments      = $"Marked as deceased through Patient Condition ({sourceTerm.DisplayName})",
                    PatientStatus = deceasedStatus
                });
            }

            return(patientCondition);
        }
Esempio n. 4
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        public void ChangeClinicalEventDetails(int patientClinicalEventId, DateTime?onsetDate, DateTime?resolutionDate, TerminologyMedDra sourceTerminology, string sourceDescription)
        {
            var patientClinicalEvent = PatientClinicalEvents.SingleOrDefault(t => t.Id == patientClinicalEventId);

            if (patientClinicalEvent == null)
            {
                throw new KeyNotFoundException($"Unable to locate clinical event {patientClinicalEventId} on patient {Id}");
            }

            if (DateOfBirth.HasValue && onsetDate.HasValue)
            {
                if (onsetDate.Value.Date < DateOfBirth.Value.Date)
                {
                    throw new DomainException("Onset Date should be after patient Date Of Birth");
                }
            }

            if (DateOfBirth.HasValue && resolutionDate.HasValue)
            {
                if (resolutionDate.Value.Date < DateOfBirth.Value.Date)
                {
                    throw new DomainException("Resolution Date should be after Date Of Birth");
                }
            }

            if (sourceTerminology != null && onsetDate.HasValue)
            {
                if (CheckEventOnsetDateAgainstOnsetDateWithNoResolutionDate(sourceTerminology.Id, onsetDate.Value, patientClinicalEventId))
                {
                    throw new DomainException("Duplication of adverse event. Please check onset and resolution dates");
                }
                else
                {
                    if (CheckEventOnsetDateWithinRange(sourceTerminology.Id, onsetDate.Value, patientClinicalEventId))
                    {
                        throw new DomainException("Duplication of adverse event. Please check onset and resolution dates");
                    }
                    else
                    {
                        if (resolutionDate.HasValue)
                        {
                            if (CheckEventOnsetDateWithNoResolutionDateBeforeOnset(sourceTerminology.Id, onsetDate.Value, patientClinicalEventId))
                            {
                                throw new DomainException("Duplication of adverse event. Please check onset and resolution dates");
                            }
                        }
                    }
                }

                // Check clinical event overlapping - RESOLUTION DATE
                if (resolutionDate.HasValue)
                {
                    if (CheckEventResolutionDateAgainstOnsetDateWithNoResolutionDate(sourceTerminology.Id, resolutionDate.Value, patientClinicalEventId))
                    {
                        throw new DomainException("Duplication of adverse event. Please check onset and resolution dates");
                    }
                    else
                    {
                        if (CheckEventResolutionDateWithinRange(sourceTerminology.Id, resolutionDate.Value, patientClinicalEventId))
                        {
                            throw new DomainException("Duplication of adverse event. Please check onset and resolution dates");
                        }
                    }
                }
            }

            patientClinicalEvent.ChangeDetails(onsetDate, resolutionDate, sourceTerminology, sourceDescription);
        }
Esempio n. 5
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        public PatientClinicalEvent AddClinicalEvent(DateTime?onsetDate, DateTime?resolutionDate, TerminologyMedDra sourceTerminology, string sourceDescription)
        {
            if (DateOfBirth.HasValue && onsetDate.HasValue)
            {
                if (onsetDate.Value.Date < DateOfBirth.Value.Date)
                {
                    throw new DomainException("Onset Date should be after patient Date Of Birth");
                }
            }

            if (DateOfBirth.HasValue && resolutionDate.HasValue)
            {
                if (resolutionDate.Value.Date < DateOfBirth.Value.Date)
                {
                    throw new DomainException("Resolution Date should be after Date Of Birth");
                }
            }

            if (sourceTerminology != null && onsetDate.HasValue)
            {
                if (CheckEventOnsetDateAgainstOnsetDateWithNoResolutionDate(sourceTerminology.Id, onsetDate.Value, 0))
                {
                    throw new DomainException("Duplication of adverse event. Please check onset and resolution dates");
                }
                else
                {
                    if (CheckEventOnsetDateWithinRange(sourceTerminology.Id, onsetDate.Value, 0))
                    {
                        throw new DomainException("Duplication of adverse event. Please check onset and resolution dates");
                    }
                    else
                    {
                        if (resolutionDate.HasValue)
                        {
                            if (CheckEventOnsetDateWithNoResolutionDateBeforeOnset(sourceTerminology.Id, onsetDate.Value, 0))
                            {
                                throw new DomainException("Duplication of adverse event. Please check onset and resolution dates");
                            }
                        }
                    }
                }

                // Check clinical event overlapping - RESOLUTION DATE
                if (resolutionDate.HasValue)
                {
                    if (CheckEventResolutionDateAgainstOnsetDateWithNoResolutionDate(sourceTerminology.Id, resolutionDate.Value, 0))
                    {
                        throw new DomainException("Duplication of adverse event. Please check onset and resolution dates");
                    }
                    else
                    {
                        if (CheckEventResolutionDateWithinRange(sourceTerminology.Id, resolutionDate.Value, 0))
                        {
                            throw new DomainException("Duplication of adverse event. Please check onset and resolution dates");
                        }
                    }
                }
            }

            var newPatientClinicalEvent = new PatientClinicalEvent(onsetDate, resolutionDate, sourceTerminology, sourceDescription);

            PatientClinicalEvents.Add(newPatientClinicalEvent);
            return(newPatientClinicalEvent);
        }