private void drawSingleDRCToolStripMenuItem_Click(object sender, EventArgs e)
{
int NumberOfReplicate = 4;
int DRCNumberofPoints = 20;
cExtendedTable FullResults = new cExtendedTable();
FullResults.ListRowNames = new List<string>();
cExtendedList ListPValues = new cExtendedList("DRC");
cDataGeneratorTitration GT = new cDataGeneratorTitration();
GT.NumberOfPoint = DRCNumberofPoints;
GT.Start = 100;
GT.DilutionFactor = 3;
GT.Run();
Random RND = new Random();
cExtendedTable FinalTable = new cExtendedTable();
cDataGeneratorSigmoid DGS = null;
DGS = new cDataGeneratorSigmoid();
DGS.SetInputData(GT.GetOutPut()[0]);
DGS.EC50 = 0.01;
DGS.Bottom = 10;
DGS.Top = 110;
DGS.Slope = 1;
DGS.Run();
// cAddNoise AN = new cAddNoise();
// AN.DistributionType = eRandDistributionType.GAUSSIAN;
double NoiseLevel = 10;
// EXT[0].Add(NoiseLevel);
// EXT[1].Add(DGS.EC50);
#region loop over the replicates
for (int NumReplic = 0; NumReplic < NumberOfReplicate; NumReplic++)
{
cExtendedList NewL = DGS.GetOutPut()[1];
for (int k = 0; k < NewL.Count; k++)
{
NewL[k] += RND.NextDouble() * NoiseLevel;
}
cExtendedTable TmpTable = new cExtendedTable();
TmpTable.Add(GT.GetOutPut()[0]);
TmpTable.Add(NewL);
if (NumReplic >= 1)
{
cMerge M = new cMerge();
M.IsHorizontal = false;
M.SetInputData(TmpTable, FinalTable);
M.Run();
FinalTable = M.GetOutPut();
}
else
FinalTable = new cExtendedTable(TmpTable);
}
#endregion
cSigmoidFitting SF = new cSigmoidFitting();
SF.SetInputData(FinalTable);
SF.Run();
cGlobalInfo.ConsoleWriteLine("Slope :" + DGS.Slope + " - Evaluated:" + SF.GetOutPut()[0][3]);
cGlobalInfo.ConsoleWriteLine("Top :" + DGS.Top + " - Evaluated:" + SF.GetOutPut()[0][1]);
cGlobalInfo.ConsoleWriteLine("Bottom :" + DGS.Bottom + " - Evaluated:" + SF.GetOutPut()[0][0]);
cGlobalInfo.ConsoleWriteLine("EC50 :" + DGS.EC50 + " - Evaluated:" + SF.GetOutPut()[0][2]);
// return;
cCurveForGraph CFG = new cCurveForGraph();
CFG.SetInputData(FinalTable);
CFG.Run();
cExtendedTable Sigmoid = SF.GetFittedRawValues(GT.GetOutPut()[0]);
FinalTable[0] = Sigmoid[1];
cViewerGraph1D VS1 = new cViewerGraph1D();
VS1.SetInputData(new cExtendedTable(Sigmoid[1]));
VS1.AddCurve(CFG);
VS1.Chart.X_AxisValues = Sigmoid[0];//DGS.GetOutPut()[0];
VS1.Chart.IsLogAxis = true;
VS1.Chart.IsLine = true;
VS1.Chart.IsShadow = true;
VS1.Chart.Opacity = 210;
VS1.Chart.LineWidth = 3;
VS1.Chart.LabelAxisX = "Concentration";
VS1.Chart.LabelAxisY = "Readout";
VS1.Chart.XAxisFormatDigitNumber = -1;
VS1.Chart.IsZoomableX = true;
VS1.Chart.IsZoomableY = true;
VS1.Run();
cDesignerSinglePanel CD = new cDesignerSinglePanel();
CD.SetInputData(VS1.GetOutPut());
CD.Run();
cDisplayToWindow DTW = new cDisplayToWindow();
DTW.SetInputData(CD.GetOutPut());//DS.GetOutPut());
DTW.Run();
DTW.Display();
}
private void sigmoidFittToolStripMenuItem_Click(object sender, EventArgs e)
{
int NumberOfReplicate = 4;
int NumberOfCurves = 30;
int DRCNumberofPoints = 12;
cExtendedTable FullResults = new cExtendedTable();
FullResults.ListRowNames = new List<string>();
double RealEC50 = 0.0001;
int NumberOfDiffEC50 = 20;
int NumberOfSlopes = 100;
// for (int EC50 = 0; EC50 < NumberOfDiffEC50; EC50++)
{
//double TmpSlopeValue = 0.0;
for (int EC50 = 0; EC50 < NumberOfDiffEC50; EC50++)
//for (int SlopeTmp = 0; SlopeTmp < NumberOfSlopes; SlopeTmp++)
{
RealEC50 *= 2;
//TmpSlopeValue += 0.1;
cExtendedList ListPValues = new cExtendedList("EC50 - " + RealEC50/*TmpSlopeValue*/);
cDesignerTab DT = new cDesignerTab();
DT.IsMultiline = false;
cDataGeneratorTitration GT = new cDataGeneratorTitration();
GT.NumberOfPoint = DRCNumberofPoints;
GT.Start = 5;
GT.DilutionFactor = 2;
GT.Run();
Random RND = new Random();
//cExtendedTable EXT = new cExtendedTable();
//EXT.ListRowNames = new List<string>();
//EXT.Name = "Quality fitting Report";
//EXT.Add(new cExtendedList("Noise Level"));
//EXT.Add(new cExtendedList("Original EC50"));
//EXT.Add(new cExtendedList("Estimated EC50"));
//EXT.Add(new cExtendedList("p-Value"));
for (int i = 0; i < NumberOfCurves; i++)
{
cExtendedTable FinalTable = new cExtendedTable();
cDataGeneratorSigmoid DGS = null;
DGS = new cDataGeneratorSigmoid();
DGS.SetInputData(GT.GetOutPut()[0]);
DGS.EC50 = RealEC50;// 0.01;// 1;// 0.1;// Math.Pow((double)10, -2);
DGS.Bottom = 0;
DGS.Top = 100;
DGS.Slope = 2;// TmpSlopeValue;//1;
DGS.Run();
cAddNoise AN = new cAddNoise();
AN.DistributionType = eRandDistributionType.GAUSSIAN;
double NoiseLevel = (i + 1) * 5;
// EXT[0].Add(NoiseLevel);
// EXT[1].Add(DGS.EC50);
#region loop over the replicates
for (int NumReplic = 0; NumReplic < NumberOfReplicate; NumReplic++)
{
//AN.Mean = 0;
//AN.Stdv = 10;
//AN.SetInputData(DGS.GetOutPut());
//AN.Run();
cExtendedList NewL = DGS.GetOutPut()[1];
for (int k = 0; k < NewL.Count; k++)
{
NewL[k] += RND.NextDouble() * NoiseLevel;
}
cExtendedTable TmpTable = new cExtendedTable();
TmpTable.Add(GT.GetOutPut()[0]);
TmpTable.Add(/*AN.GetOutPut()[1]*/NewL);
if (NumReplic >= 1)
{
cMerge M = new cMerge();
M.IsHorizontal = false;
M.SetInputData(TmpTable, FinalTable);
M.Run();
FinalTable = M.GetOutPut();
}
else
FinalTable = new cExtendedTable(TmpTable);
}
#endregion
//cListWell LW = new cListWell(null);
//foreach (cWell item in CompleteScreening.GetCurrentDisplayPlate().ListActiveWells)
//{
// if (item.GetClassIdx() == 0)
// LW.Add(item);
//}
//cExtendedTable ET = LW.GetDescriptorValues(CompleteScreening.ListDescriptors.GetActiveDescriptors(), true);
cCurveForGraph CFG = new cCurveForGraph();
CFG.SetInputData(FinalTable);
CFG.Run();
// compute ANOVA
cANOVA S = new cANOVA();
cExtendedTable NewTable = CFG.ListPtValues.Crop(0, CFG.ListPtValues.Count - 1, 1, CFG.ListPtValues[0].Count - 1);
S.SignificanceThreshold = 1E-11;
S.SetInputData(NewTable);
S.Run();
//cLinearRegression LR = new cLinearRegression();
//LR.SetInputData(FinalTable);
//LR.Run();
cSigmoidFitting SF = new cSigmoidFitting();
SF.SetInputData(FinalTable);
if (SF.Run().IsSucceed == false) continue;
// double Ratio = LR.GetOutPut()[0][LR.GetOutPut().Count - 1] / SF.GetOutPut()[0][SF.GetOutPut().Count - 1];
cExtendedTable Sigmoid = SF.GetFittedRawValues(GT.GetOutPut()[0]);
FinalTable[0] = Sigmoid[1];
cDesignerSplitter DS = new cDesignerSplitter();
////cViewerTableAsRichText VT = new cViewerTableAsRichText();
cViewerTable VT = new cViewerTable();
cExtendedTable TableResults = SF.GetOutPut();
TableResults[0].Add(S.GetOutPut()[0][0]);
ListPValues.Add(S.GetOutPut()[0][0]);
TableResults[0].Add(S.GetOutPut()[0][1]);
TableResults.ListRowNames.Add("p-Value");
TableResults.ListRowNames.Add("Null hyp. rejected?");
VT.SetInputData(TableResults);
VT.DigitNumber = -1;
VT.Run();
cViewerGraph1D VS1 = new cViewerGraph1D();
VS1.SetInputData(new cExtendedTable(Sigmoid[1]));
VS1.AddCurve(CFG);
VS1.Chart.X_AxisValues = Sigmoid[0];//DGS.GetOutPut()[0];
VS1.Chart.IsLogAxis = true;
VS1.Chart.IsLine = true;
VS1.Chart.IsShadow = true;
VS1.Chart.Opacity = 210;
VS1.Chart.LineWidth = 3;
VS1.Chart.LabelAxisX = "Concentration";
VS1.Chart.LabelAxisY = "Readout";
VS1.Chart.XAxisFormatDigitNumber = -1;
VS1.Chart.IsZoomableX = true;
//Classes.Base_Classes.General.cLineVerticalForGraph VLForEC50 = new Classes.Base_Classes.General.cLineVerticalForGraph(SF.GetOutPut()[0][2]);
//VLForEC50.AddText("EC50: " + SF.GetOutPut()[0][2].ToString("e3")/* + "\nError Ratio:" + Ratio.ToString("N4")*/);
//VS1.Chart.ListVerticalLines.Add(VLForEC50);
//VS1.Chart.ArraySeriesInfo = new cSerieInfoDesign[FinalTable.Count];
//EXT[2].Add(SF.GetOutPut()[0][2]);
//EXT[3].Add(S.GetOutPut()[0][0]);
//for (int IdxCurve = 0; IdxCurve < FinalTable.Count; IdxCurve++)
//{
// cSerieInfoDesign TmpSerieInfo = new cSerieInfoDesign();
// TmpSerieInfo.color = Color.FromArgb(100, GlobalInfo.ListCellularPhenotypes[IdxCurve % GlobalInfo.ListCellularPhenotypes.Count].ColourForDisplay);
// TmpSerieInfo.markerStyle = MarkerStyle.Circle;
// VS1.Chart.ArraySeriesInfo[IdxCurve] = TmpSerieInfo;
//}
VS1.Run();
DS.SetInputData(VS1.GetOutPut());
DS.SetInputData(VT.GetOutPut());
DS.Orientation = Orientation.Horizontal;
DS.Title = "Noise Stdev " + NoiseLevel;
DS.Run();
DT.SetInputData(DS.GetOutPut());
// EXT.ListRowNames.Add(DS.Title);
}
DT.Run();
//cDisplayToWindow DTW = new cDisplayToWindow();
//DTW.SetInputData(DT.GetOutPut());
//DTW.Run();
//DTW.Display();
//cDisplayExtendedTable DET = new cDisplayExtendedTable();
//DET.SetInputData(EXT);
//DET.DigitNumber = -1;
//DET.Run();
FullResults.Add(ListPValues);
}
}
cDisplayExtendedTable DET = new cDisplayExtendedTable();
DET.SetInputData(FullResults);
DET.DigitNumber = -1;
DET.Run();
}
private void dToolStripMenuItem_Click(object sender, EventArgs e)
{
cFeedBackMessage MessageReturned;
cGUI_ListClasses GUI_ListClasses = new cGUI_ListClasses();
GUI_ListClasses.IsCheckBoxes = true;
GUI_ListClasses.IsSelectAll = true;
if (GUI_ListClasses.Run().IsSucceed == false) return;
cExtendedList ListClassSelected = GUI_ListClasses.GetOutPut()[0];
List<cWellClassType> ListWellClassesSelected = new List<cWellClassType>();
foreach (var item in ListClassSelected.ListTags)
{
ListWellClassesSelected.Add((cWellClassType)(item));
}
cViewerGraph1D V1D = new cViewerGraph1D();
V1D.Chart.IsSelectable = true;
V1D.Chart.LabelAxisX = "Well Index";
V1D.Chart.LabelAxisY = cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();
V1D.Chart.IsXGrid = true;
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
{
cExtendedTable DataFromPlate = new cExtendedTable(cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate().ListActiveWells,
cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx, ListClassSelected);
DataFromPlate.Name = cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate().GetName();
V1D.Chart.IsShadow = true;
V1D.Chart.IsBorder = true;
//V1D.Chart.IsSelectable = true;
V1D.Chart.CurrentTitle.Tag = cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate();
V1D.SetInputData(DataFromPlate);
V1D.Run();
cDesignerSplitter DS = new cDesignerSplitter();
DS.Orientation = System.Windows.Forms.Orientation.Horizontal;
DS.SetInputData(V1D.GetOutPut());
cExtendedTable NewTable = cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate().ListActiveWells.Filter(ListWellClassesSelected).GetAverageDescriptorValues(cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx);
NewTable.Name = "Histogram";
cViewerStackedHistogram CV1 = new cViewerStackedHistogram();
CV1.SetInputData(NewTable);
CV1.Chart.LabelAxisX = cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();
CV1.Run();
DS.SetInputData(CV1.GetOutPut());
DS.Run();
cDisplayToWindow Disp0 = new cDisplayToWindow();
Disp0.SetInputData(DS.GetOutPut());
Disp0.Title = "Scatter points graph - " + DataFromPlate[0].Count + " wells.";
if (!Disp0.Run().IsSucceed) return;
Disp0.Display();
}
else if (ProcessModeEntireScreeningToolStripMenuItem.Checked)
{
V1D.Chart.MarkerSize = 5;
V1D.Chart.IsBorder = false;
V1D.Chart.IsShadow = false;
cListWells ListWell = new cListWells(null);
int IdxWellForPlateSeparator = 0;
foreach (cPlate TmpPlate in cGlobalInfo.CurrentScreening.ListPlatesActive)
{
foreach (cWell TmpWell in TmpPlate.ListActiveWells)
{
int ClassTmp = TmpWell.GetCurrentClassIdx();
if ((ClassTmp == -1) || (GUI_ListClasses.GetOutPut()[0][TmpWell.GetCurrentClassIdx()] == 0)) continue;
ListWell.Add(TmpWell);
IdxWellForPlateSeparator++;
}
if (cGlobalInfo.OptionsWindow.FFAllOptions.checkBoxDisplayPlatesVerticalLines.Checked)
{
Classes.Base_Classes.General.cLineVerticalForGraph VL = new Classes.Base_Classes.General.cLineVerticalForGraph(IdxWellForPlateSeparator + 0.5);
VL.IsAllowMoving = false;
V1D.Chart.ListVerticalLines.Add(VL);
}
}
cExtendedTable DataFromPlate = new cExtendedTable(ListWell,
cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx, ListClassSelected);
DataFromPlate.Name = cGlobalInfo.CurrentScreening.GetName() + " - " + cGlobalInfo.CurrentScreening.ListPlatesActive.Count + " plates";
int MaxNumberOfPts = (int)cGlobalInfo.OptionsWindow.FFAllOptions.numericUpDownMinNumPointForFastDisp.Value;
if (ListWell.Count > MaxNumberOfPts)
{
cGlobalInfo.WindowHCSAnalyzer.richTextBoxConsole.AppendText("\n" + V1D.Title + ": Number of Wells is Higher than " + MaxNumberOfPts + " => Switching to FastPoints Mode.\n");
V1D.Chart.ISFastPoint = true;
}
V1D.SetInputData(DataFromPlate);
V1D.Run();
cDesignerSplitter DS = new cDesignerSplitter();
DS.Orientation = System.Windows.Forms.Orientation.Horizontal;
DS.SetInputData(V1D.GetOutPut());
cExtendedTable NewTable = ListWell.GetAverageDescriptorValues(cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx);
NewTable.Name = "Histogram";
cViewerStackedHistogram CV1 = new cViewerStackedHistogram();
CV1.SetInputData(NewTable);
CV1.Chart.LabelAxisX = cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();
CV1.Run();
DS.SetInputData(CV1.GetOutPut());
DS.Run();
cDisplayToWindow Disp0 = new cDisplayToWindow();
Disp0.SetInputData(DS.GetOutPut());
Disp0.Title = "Scatter points graph - " + DataFromPlate[0].Count + " wells.";
if (!Disp0.Run().IsSucceed) return;
Disp0.Display();
}
else if (ProcessModeplateByPlateToolStripMenuItem.Checked)
{
cDesignerTab CDT = new cDesignerTab();
foreach (cPlate TmpPlate in cGlobalInfo.CurrentScreening.ListPlatesActive)
{
cExtendedTable DataFromPlate = new cExtendedTable(TmpPlate.ListActiveWells,
cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx, ListClassSelected);
DataFromPlate.Name = TmpPlate.GetName();
V1D = new cViewerGraph1D();
V1D.Chart.IsSelectable = true;
V1D.Chart.LabelAxisX = "Well Index";
V1D.Chart.LabelAxisY = cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();
V1D.Chart.IsXGrid = true;
V1D.Chart.CurrentTitle.Tag = TmpPlate;
V1D.SetInputData(DataFromPlate);
V1D.Title = TmpPlate.GetName();
V1D.Run();
cDesignerSplitter DS = new cDesignerSplitter();
DS.Orientation = System.Windows.Forms.Orientation.Horizontal;
DS.SetInputData(V1D.GetOutPut());
cExtendedTable NewTable = TmpPlate.ListActiveWells.Filter(ListWellClassesSelected).GetAverageDescriptorValues(cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx);
NewTable.Name = "Histogram";
cViewerStackedHistogram CV1 = new cViewerStackedHistogram();
CV1.SetInputData(NewTable);
CV1.Chart.LabelAxisX = cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();
CV1.Run();
DS.Title = TmpPlate.GetName();
DS.SetInputData(CV1.GetOutPut());
DS.Run();
CDT.SetInputData(DS.GetOutPut());
}
CDT.Run();
cDisplayToWindow Disp0 = new cDisplayToWindow();
Disp0.SetInputData(CDT.GetOutPut());
Disp0.Title = "Scatter points graphs";
if (!Disp0.Run().IsSucceed) return;
Disp0.Display();
}
}
private void mannWithneyTestToolStripMenuItem_Click(object sender, EventArgs e)
{
cGUI_2ClassesSelection GUI_ListClasses = new cGUI_2ClassesSelection();
if (GUI_ListClasses.Run(this.GlobalInfo).IsSucceed == false) return;
cExtendedTable ListClassSelected = GUI_ListClasses.GetOutPut();
int IdxClassNeg = -1;
int IdxClassPos = -1;
for (int IdxC = 0; IdxC < ListClassSelected[0].Count; IdxC++)
{
if (ListClassSelected[0][IdxC] == 1) IdxClassNeg = IdxC;
if (ListClassSelected[1][IdxC] == 1) IdxClassPos = IdxC;
}
string SubTitle = "Mann-Withney (both tails)";
#region single plate and plate by plate
cDesignerTab DT = new cDesignerTab();
if ((ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked) || (ProcessModeplateByPlateToolStripMenuItem.Checked)/*||(ProcessModeEntireScreeningToolStripMenuItem.Checked)*/)
{
List<cPlate> ListPlatesToProcess = new List<cPlate>();
if ((ProcessModeplateByPlateToolStripMenuItem.Checked)/*||(ProcessModeEntireScreeningToolStripMenuItem.Checked)*/)
{
foreach (cPlate TmpPlate in cGlobalInfo.CurrentScreening.ListPlatesActive)
ListPlatesToProcess.Add(TmpPlate);
}
else
ListPlatesToProcess.Add(cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate());
foreach (cPlate TmpPlate in ListPlatesToProcess)
{
cListWells ListWellsToProcess1 = new cListWells(null);
cListWells ListWellsToProcess2 = new cListWells(null);
foreach (cWell item in TmpPlate.ListActiveWells)
{
if (item.GetCurrentClassIdx() != -1)
{
if (ListClassSelected[0][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess1.Add(item);
if (ListClassSelected[1][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess2.Add(item);
}
}
cExtendedTable NewTable1 = new cExtendedTable(ListWellsToProcess1, true);
cExtendedTable NewTable2 = new cExtendedTable(ListWellsToProcess2, true);
if ((NewTable1.Count == 0) || (NewTable1[0].Count < 5) || (NewTable2.Count == 0) || (NewTable2[0].Count < 5))
{
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
{
MessageBox.Show("Insufficient number of control wells", "Error", MessageBoxButtons.OK, MessageBoxIcon.Error);
return;
}
else
continue;
}
cExtendedList ListZ = new cExtendedList();
List<cDescriptorType> ListDescForZFactor = new List<cDescriptorType>();
List<string> ListNames = new List<string>();
int RealIdx = 0;
for (int IDxDesc = 0; IDxDesc < cGlobalInfo.CurrentScreening.ListDescriptors.Count; IDxDesc++)
{
if (!cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc].IsActive()) continue;
cExtendedTable TableForZ = new cExtendedTable();
TableForZ.Add(NewTable1[RealIdx]);
TableForZ.Add(NewTable2[RealIdx]);
RealIdx++;
cMannWithneyTest ZF = new cMannWithneyTest();
ZF.SetInputData(TableForZ);
ZF.Run();
ListZ.Add(ZF.GetOutPut()[0][1]);
ListDescForZFactor.Add(cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc]);
}
cExtendedTable ET = new cExtendedTable(new cExtendedTable(ListZ));
ET[0].ListTags = new List<object>();
ET[0].ListTags.AddRange(ListDescForZFactor);
ET.Name = TmpPlate.GetName() + "\n" + SubTitle + " - " + cGlobalInfo.ListWellClasses[IdxClassNeg].Name + " (" + NewTable1[0].Count + " wells) vs. " + cGlobalInfo.ListWellClasses[IdxClassPos].Name + " (" + NewTable2[0].Count + " wells)";
ET[0].Name = ET.Name;
cSort S = new cSort();
S.SetInputData(ET);
S.ColumnIndexForSorting = 0;
S.Run();
//ZFactorList.Sort(delegate(cSimpleSignature p1, cSimpleSignature p2) { return p1.AverageValue.CompareTo(p2.AverageValue); });
cViewerGraph1D VG1 = new cViewerGraph1D();
VG1.SetInputData(S.GetOutPut());
VG1.Chart.LabelAxisY = SubTitle;
VG1.Chart.LabelAxisX = "Descriptor";
VG1.Chart.IsZoomableX = true;
VG1.Chart.IsBar = true;
VG1.Chart.IsBorder = true;
VG1.Chart.IsDisplayValues = true;
VG1.Chart.IsShadow = true;
VG1.Chart.MarkerSize = 4;
//VG1.Chart.Max
VG1.Title = TmpPlate.GetName();
Classes.Base_Classes.General.cLineHorizontalForGraph VLZ05 = new Classes.Base_Classes.General.cLineHorizontalForGraph(.05);
VLZ05.IsAllowMoving = true;
VG1.Chart.ListHorizontalLines.Add(VLZ05);
VG1.Run();
cDesignerSplitter DS = new cDesignerSplitter();
DS.Orientation = Orientation.Vertical;
DS.SetInputData(VG1.GetOutPut());
cSort S1 = new cSort();
S1.SetInputData(ET);
S1.ColumnIndexForSorting = 0;
S1.IsAscending = false;
S1.Run();
cViewerTable VT = new cViewerTable();
VT.SetInputData(S1.GetOutPut());
VT.DigitNumber = -1;
VT.Run();
DS.SetInputData(VT.GetOutPut());
DS.Title = TmpPlate.GetName();
DS.Run();
DT.SetInputData(DS.GetOutPut());
}
DT.Run();
cDisplayToWindow CDW = new cDisplayToWindow();
CDW.SetInputData(DT.GetOutPut());//VG1.GetOutPut());
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
CDW.Title = SubTitle + " - " + ListPlatesToProcess[0].GetName();
else
CDW.Title = SubTitle + " - " + ListPlatesToProcess.Count + " plates";
CDW.Run();
CDW.Display();
}
#endregion
#region entire screening
else if (ProcessModeEntireScreeningToolStripMenuItem.Checked)
{
List<cPlate> ListPlatesToProcess = new List<cPlate>();
foreach (cPlate TmpPlate in cGlobalInfo.CurrentScreening.ListPlatesActive)
ListPlatesToProcess.Add(TmpPlate);
cExtendedList ListZ = new cExtendedList();
List<cPlate> ListPlatesForZFactor = new List<cPlate>();
foreach (cPlate TmpPlate in ListPlatesToProcess)
{
cListWells ListWellsToProcess1 = new cListWells(null);
cListWells ListWellsToProcess2 = new cListWells(null);
foreach (cWell item in TmpPlate.ListActiveWells)
{
if (item.GetCurrentClassIdx() != -1)
{
if (ListClassSelected[0][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess1.Add(item);
if (ListClassSelected[1][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess2.Add(item);
}
}
cExtendedTable NewTable1 = new cExtendedTable(ListWellsToProcess1, cGlobalInfo.CurrentScreening.ListDescriptors.GetDescriptorIndex(cGlobalInfo.CurrentScreening.ListDescriptors.GetActiveDescriptor()));
cExtendedTable NewTable2 = new cExtendedTable(ListWellsToProcess2, cGlobalInfo.CurrentScreening.ListDescriptors.GetDescriptorIndex(cGlobalInfo.CurrentScreening.ListDescriptors.GetActiveDescriptor()));
//cExtendedTable NewTable2 = new cExtendedTable(ListWellsToProcess2, false);
if ((NewTable1.Count == 0) || (NewTable1[0].Count < 5) || (NewTable2.Count == 0) || (NewTable2[0].Count < 5))
{
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
{
MessageBox.Show("Insufficient number of control wells", "Error", MessageBoxButtons.OK, MessageBoxIcon.Error);
return;
}
else
continue;
}
cExtendedTable TableForZ = new cExtendedTable();
TableForZ.Add(NewTable1[0]);
TableForZ.Add(NewTable2[0]);
cMannWithneyTest ZF = new cMannWithneyTest();
ZF.SetInputData(TableForZ);
ZF.Run();
double Zfactor = ZF.GetOutPut()[0][1];
ListZ.Add(Zfactor);
// update plate quality
//TmpPlate.ListProperties.UpdateValueByName("Quality", Math.Exp(Zfactor - 1));
//cProperty Prop = TmpPlate.ListProperties.FindByName("Quality");
//Prop.Info = ZF.GetInfo();
ListPlatesForZFactor.Add(TmpPlate);
}
cExtendedTable ET = new cExtendedTable(new cExtendedTable(ListZ));
ET[0].ListTags = new List<object>();
ET[0].ListTags.AddRange(ListPlatesForZFactor);
ET.Name = SubTitle + " - " + cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName() + " - " + cGlobalInfo.ListWellClasses[IdxClassNeg].Name + /*" (" + NewTable1[0].Count + " wells)*/ " vs. " + cGlobalInfo.ListWellClasses[IdxClassPos].Name;// +" (" + NewTable2[0].Count + " wells)";
ET[0].Name = ET.Name;
cViewerGraph1D VG1 = new cViewerGraph1D();
VG1.SetInputData(ET);
VG1.Chart.LabelAxisY = SubTitle;
VG1.Chart.LabelAxisX = "Plate";
VG1.Chart.IsZoomableX = true;
VG1.Chart.IsBar = true;
VG1.Chart.IsBorder = true;
VG1.Chart.IsDisplayValues = true;
VG1.Chart.IsShadow = true;
VG1.Chart.MarkerSize = 4;
Classes.Base_Classes.General.cLineHorizontalForGraph VLZ05 = new Classes.Base_Classes.General.cLineHorizontalForGraph(.05);
VLZ05.IsAllowMoving = true;
VG1.Chart.ListHorizontalLines.Add(VLZ05);
VG1.Title = cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();
VG1.Run();
cDisplayToWindow CDW = new cDisplayToWindow();
CDW.SetInputData(VG1.GetOutPut());
CDW.Title = SubTitle + " - " + ListPlatesToProcess.Count + " plates";
CDW.Run();
CDW.Display();
#endregion
}
}
private void aNOVAToolStripMenuItem1_Click(object sender, EventArgs e)
{
cGUI_ListClasses GUI_ListClasses = new cGUI_ListClasses();
GUI_ListClasses.IsCheckBoxes = true;
GUI_ListClasses.IsSelectAll = true;
if (GUI_ListClasses.Run().IsSucceed == false) return;
cExtendedTable ListClassSelected = GUI_ListClasses.GetOutPut();
string SubTitle = "ANOVA (One-Way)";
#region single plate and plate by plate
cDesignerTab DT = new cDesignerTab();
if ((ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked) || (ProcessModeplateByPlateToolStripMenuItem.Checked)/*||(ProcessModeEntireScreeningToolStripMenuItem.Checked)*/)
{
List<cPlate> ListPlatesToProcess = new List<cPlate>();
if ((ProcessModeplateByPlateToolStripMenuItem.Checked)/*||(ProcessModeEntireScreeningToolStripMenuItem.Checked)*/)
{
foreach (cPlate TmpPlate in cGlobalInfo.CurrentScreening.ListPlatesActive)
ListPlatesToProcess.Add(TmpPlate);
}
else
ListPlatesToProcess.Add(cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate());
foreach (cPlate TmpPlate in ListPlatesToProcess)
{
cExtendedTable NewTable1 = new cExtendedTable();
List<cListWells> ListListWells = new List<cListWells>();
int NumWells = 0;
for (int IdxClassWell = 0; IdxClassWell < ListClassSelected[0].Count; IdxClassWell++)
{
if (ListClassSelected[0][IdxClassWell] >= 1)
{
List<cWellClassType> LCT = new List<cWellClassType>();
LCT.Add(cGlobalInfo.ListWellClasses[IdxClassWell]);
cListWells TmpList = TmpPlate.ListWells.Filter(LCT);
if (TmpList.Count >= 3)
{
ListListWells.Add(TmpList);
NumWells += TmpList.Count;
}
}
}
if (ListListWells.Count <= 1)
{
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
{
MessageBox.Show("Insufficient number of control wells", "Error", MessageBoxButtons.OK, MessageBoxIcon.Error);
return;
}
else
continue;
}
cExtendedTable CompleteReport = null;
cExtendedList ListZ = new cExtendedList();
List<cDescriptorType> ListDescForZFactor = new List<cDescriptorType>();
List<string> ListNames = new List<string>();
int RealIdx = 0;
for (int IDxDesc = 0; IDxDesc < cGlobalInfo.CurrentScreening.ListDescriptors.Count; IDxDesc++)
{
if (!cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc].IsActive()) continue;
cExtendedTable TableForZ = new cExtendedTable();
foreach (var item in ListListWells)
{
List<cDescriptorType> LType = new List<cDescriptorType>();
LType.Add(cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc]);
cExtendedTable TTable = item.GetAverageDescriptorValues(LType, false, false);
TableForZ.Add(TTable[0]);
}
RealIdx++;
cANOVA ZF = new cANOVA();
ZF.SetInputData(TableForZ);
ZF.Run();
ListZ.Add(ZF.GetOutPut()[0][0]);
ZF.GetOutPut()[0].Name = cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc].GetName();
if (CompleteReport == null)
CompleteReport = new cExtendedTable(ZF.GetOutPut());
else
{
cMerge M = new cMerge();
M.IsHorizontal = true;
M.SetInputData(CompleteReport, ZF.GetOutPut());
M.Run();
CompleteReport = M.GetOutPut();
}
ListDescForZFactor.Add(cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc]);
}
cExtendedTable ET = new cExtendedTable(new cExtendedTable(ListZ));
ET[0].ListTags = new List<object>();
ET[0].ListTags.AddRange(ListDescForZFactor);
ET.Name = TmpPlate.GetName() + "\n" + SubTitle + " - " + NumWells + " wells";// +" - " +cGlobalInfo.ListWellClasses[IdxClassNeg].Name + " (" + NewTable1[0].Count + " wells) vs. " +cGlobalInfo.ListWellClasses[IdxClassPos].Name + " (" + NewTable2[0].Count + " wells)";
ET[0].Name = ET.Name;
cSort S = new cSort();
S.SetInputData(ET);
S.IsAscending = false;
S.ColumnIndexForSorting = 0;
S.Run();
//ZFactorList.Sort(delegate(cSimpleSignature p1, cSimpleSignature p2) { return p1.AverageValue.CompareTo(p2.AverageValue); });
cViewerGraph1D VG1 = new cViewerGraph1D();
VG1.SetInputData(S.GetOutPut());
VG1.Chart.LabelAxisY = SubTitle;
VG1.Chart.LabelAxisX = "Descriptor";
VG1.Chart.IsZoomableX = true;
VG1.Chart.IsBar = true;
VG1.Chart.IsBorder = true;
VG1.Chart.IsDisplayValues = true;
VG1.Chart.IsShadow = true;
VG1.Chart.MarkerSize = 4;
//VG1.Chart.Max
VG1.Title = TmpPlate.GetName();
// Classes.Base_Classes.General.cLineHorizontalForGraph VLZ05 = new Classes.Base_Classes.General.cLineHorizontalForGraph(.05);
// VLZ05.IsAllowMoving = true;
// VG1.Chart.ListHorizontalLines.Add(VLZ05);
VG1.Run();
cDesignerSplitter DS = new cDesignerSplitter();
DS.Orientation = Orientation.Vertical;
DS.SetInputData(VG1.GetOutPut());
cTranspose T = new cTranspose();
T.SetInputData(CompleteReport);
T.Run();
CompleteReport = T.GetOutPut();
CompleteReport[0].Name = "P-Value";
CompleteReport[1].Name = "Is significant ?";
cSort S1 = new cSort();
S1.SetInputData(CompleteReport);
S1.ColumnIndexForSorting = 0;
S1.IsAscending = true;
S1.Run();
cViewerTable VT = new cViewerTable();
VT.SetInputData(S1.GetOutPut());
VT.DigitNumber = -1;
VT.Run();
DS.SetInputData(VT.GetOutPut());
DS.Title = TmpPlate.GetName();
DS.Run();
DT.SetInputData(DS.GetOutPut());
}
DT.Run();
cDisplayToWindow CDW = new cDisplayToWindow();
CDW.SetInputData(DT.GetOutPut());//VG1.GetOutPut());
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
CDW.Title = SubTitle + " - " + ListPlatesToProcess[0].GetName();
else
CDW.Title = SubTitle + " - " + ListPlatesToProcess.Count + " plates";
CDW.Run();
CDW.Display();
}
#endregion
#region entire screening
else if (ProcessModeEntireScreeningToolStripMenuItem.Checked)
{
List<cPlate> ListPlatesToProcess = new List<cPlate>();
foreach (cPlate TmpPlate in cGlobalInfo.CurrentScreening.ListPlatesActive)
ListPlatesToProcess.Add(TmpPlate);
cExtendedList ListZ = new cExtendedList();
List<cPlate> ListPlatesForZFactor = new List<cPlate>();
foreach (cPlate TmpPlate in ListPlatesToProcess)
{
cListWells ListWellsToProcess1 = new cListWells(null);
cListWells ListWellsToProcess2 = new cListWells(null);
foreach (cWell item in TmpPlate.ListActiveWells)
{
if (item.GetCurrentClassIdx() != -1)
{
if (ListClassSelected[0][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess1.Add(item);
if (ListClassSelected[1][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess2.Add(item);
}
}
cExtendedTable NewTable1 = new cExtendedTable(ListWellsToProcess1, cGlobalInfo.CurrentScreening.ListDescriptors.GetDescriptorIndex(cGlobalInfo.CurrentScreening.ListDescriptors.GetActiveDescriptor()));
cExtendedTable NewTable2 = new cExtendedTable(ListWellsToProcess2, cGlobalInfo.CurrentScreening.ListDescriptors.GetDescriptorIndex(cGlobalInfo.CurrentScreening.ListDescriptors.GetActiveDescriptor()));
//cExtendedTable NewTable2 = new cExtendedTable(ListWellsToProcess2, false);
if ((NewTable1.Count == 0) || (NewTable1[0].Count < 2) || (NewTable2.Count == 0) || (NewTable2[0].Count < 2))
{
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
{
MessageBox.Show("Insufficient number of control wells", "Error", MessageBoxButtons.OK, MessageBoxIcon.Error);
return;
}
else
continue;
}
cExtendedTable TableForZ = new cExtendedTable();
TableForZ.Add(NewTable1[0]);
TableForZ.Add(NewTable2[0]);
cStudent_tTest ZF = new cStudent_tTest();
ZF.SetInputData(TableForZ);
ZF.Run();
double Zfactor = ZF.GetOutPut()[0][1];
ListZ.Add(Zfactor);
// update plate quality
//TmpPlate.ListProperties.UpdateValueByName("Quality", Math.Exp(Zfactor - 1));
//cProperty Prop = TmpPlate.ListProperties.FindByName("Quality");
//Prop.Info = ZF.GetInfo();
ListPlatesForZFactor.Add(TmpPlate);
}
cExtendedTable ET = new cExtendedTable(new cExtendedTable(ListZ));
ET[0].ListTags = new List<object>();
ET[0].ListTags.AddRange(ListPlatesForZFactor);
ET.Name = SubTitle + " - " + cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();// +" - " +cGlobalInfo.ListWellClasses[IdxClassNeg].Name + /*" (" + NewTable1[0].Count + " wells)*/ " vs. " +cGlobalInfo.ListWellClasses[IdxClassPos].Name;// +" (" + NewTable2[0].Count + " wells)";
ET[0].Name = ET.Name;
cViewerGraph1D VG1 = new cViewerGraph1D();
VG1.SetInputData(ET);
VG1.Chart.LabelAxisY = SubTitle;
VG1.Chart.LabelAxisX = "Plate";
VG1.Chart.IsZoomableX = true;
VG1.Chart.IsBar = true;
VG1.Chart.IsBorder = true;
VG1.Chart.IsDisplayValues = true;
VG1.Chart.IsShadow = true;
VG1.Chart.MarkerSize = 4;
VG1.Title = cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();
VG1.Run();
cDisplayToWindow CDW = new cDisplayToWindow();
CDW.SetInputData(VG1.GetOutPut());
CDW.Title = SubTitle + " - " + ListPlatesToProcess.Count + " plates";
CDW.Run();
CDW.Display();
#endregion
}
}
private void zScoreToolStripMenuItem_Click(object sender, EventArgs e)
{
#region obsolete
//List<double> Pos = new List<double>();
//List<double> Neg = new List<double>();
//List<cSimpleSignature> ZFactorList = new List<cSimpleSignature>();
//int NumDesc = CompleteScreening.ListDescriptors.Count;
//cWell TempWell;
//// loop on all the desciptors
//for (int Desc = 0; Desc < NumDesc; Desc++)
//{
// Pos.Clear();
// Neg.Clear();
// if (CompleteScreening.ListDescriptors[Desc].IsActive() == false) continue;
// for (int row = 0; row < CompleteScreening.Rows; row++)
// for (int col = 0; col < CompleteScreening.Columns; col++)
// {
// TempWell = CompleteScreening.GetCurrentDisplayPlate().GetWell(col, row, true);
// if (TempWell == null) continue;
// else
// {
// if (TempWell.GetClassIdx() == 0)
// Pos.Add(TempWell.ListDescriptors[Desc].GetValue());
// if (TempWell.GetClassIdx() == 1)
// Neg.Add(TempWell.ListDescriptors[Desc].GetValue());
// }
// }
// if (Pos.Count < 3)
// {
// MessageBox.Show("No or not enough positive controls !", "Warning", MessageBoxButtons.OK, MessageBoxIcon.Exclamation);
// return;
// }
// if (Neg.Count < 3)
// {
// MessageBox.Show("No or not enough negative controls !", "Warning", MessageBoxButtons.OK, MessageBoxIcon.Exclamation);
// return;
// }
// double ZScore = 1 - 3 * (std(Pos.ToArray()) + std(Neg.ToArray())) / (Math.Abs(Mean(Pos.ToArray()) - Mean(Neg.ToArray())));
// GlobalInfo.ConsoleWriteLine(CompleteScreening.ListDescriptors[Desc].GetName() + ", Z-Score = " + ZScore);
// cSimpleSignature TmpDesc = new cSimpleSignature(CompleteScreening.ListDescriptors[Desc].GetName(), ZScore);
// ZFactorList.Add(TmpDesc);
//}
//ZFactorList.Sort(delegate(cSimpleSignature p1, cSimpleSignature p2) { return p1.AverageValue.CompareTo(p2.AverageValue); });
//Series CurrentSeries = new Series();
//CurrentSeries.ChartType = SeriesChartType.Column;
//CurrentSeries.ShadowOffset = 1;
//Series SeriesLine = new Series();
//SeriesLine.Name = "SeriesLine";
//SeriesLine.ShadowOffset = 1;
//SeriesLine.ChartType = SeriesChartType.Line;
//int RealIdx = 0;
//for (int IdxValue = 0; IdxValue < ZFactorList.Count; IdxValue++)
//{
// if (double.IsNaN(ZFactorList[IdxValue].AverageValue)) continue;
// if (double.IsInfinity(ZFactorList[IdxValue].AverageValue)) continue;
// CurrentSeries.Points.Add(ZFactorList[IdxValue].AverageValue);
// CurrentSeries.Points[RealIdx].Label = ZFactorList[IdxValue].AverageValue.ToString("N2");
// CurrentSeries.Points[RealIdx].Font = new Font("Arial", 10);
// CurrentSeries.Points[RealIdx].ToolTip = ZFactorList[IdxValue].Name;
// CurrentSeries.Points[RealIdx].AxisLabel = ZFactorList[IdxValue].Name;
// SeriesLine.Points.Add(ZFactorList[IdxValue].AverageValue);
// SeriesLine.Points[RealIdx].BorderColor = Color.Black;
// SeriesLine.Points[RealIdx].MarkerStyle = MarkerStyle.Circle;
// SeriesLine.Points[RealIdx].MarkerSize = 4;
// RealIdx++;
//}
//SimpleForm NewWindow = new SimpleForm(CompleteScreening);
//int thisWidth = 200 * RealIdx;
//if (thisWidth > (int)GlobalInfo.OptionsWindow.numericUpDownMaximumWidth.Value) thisWidth = (int)GlobalInfo.OptionsWindow.numericUpDownMaximumWidth.Value;
//NewWindow.Width = thisWidth;
//NewWindow.Height = 400;
//NewWindow.Text = "Z-factors";
//ChartArea CurrentChartArea = new ChartArea();
//CurrentChartArea.BorderColor = Color.Black;
//CurrentChartArea.AxisX.Interval = 1;
//NewWindow.chartForSimpleForm.Series.Add(CurrentSeries);
//NewWindow.chartForSimpleForm.Series.Add(SeriesLine);
//CurrentChartArea.AxisX.IsLabelAutoFit = true;
//NewWindow.chartForSimpleForm.ChartAreas.Add(CurrentChartArea);
//CurrentChartArea.Axes[1].Maximum = 2;
//CurrentChartArea.Axes[1].IsMarksNextToAxis = true;
//CurrentChartArea.Axes[0].MajorGrid.Enabled = false;
//CurrentChartArea.Axes[1].MajorGrid.Enabled = false;
//NewWindow.chartForSimpleForm.TextAntiAliasingQuality = TextAntiAliasingQuality.High;
//CurrentChartArea.BackGradientStyle = GradientStyle.TopBottom;
//CurrentChartArea.BackColor = CompleteScreening.GlobalInfo.OptionsWindow.panel1.BackColor;
//CurrentChartArea.BackSecondaryColor = Color.White;
//CurrentChartArea.AxisX.ScaleView.Zoomable = true;
//CurrentChartArea.AxisY.ScaleView.Zoomable = true;
//Title CurrentTitle = new Title(CompleteScreening.GetCurrentDisplayPlate().Name + " Z-factors");
//CurrentTitle.Font = new System.Drawing.Font("Arial", 11, FontStyle.Bold);
//NewWindow.chartForSimpleForm.Titles.Add(CurrentTitle);
//NewWindow.Show();
//NewWindow.chartForSimpleForm.Update();
//NewWindow.chartForSimpleForm.Show();
//NewWindow.AutoScroll = true;
//NewWindow.Controls.AddRange(new System.Windows.Forms.Control[] { NewWindow.chartForSimpleForm });
#endregion
cGUI_2ClassesSelection GUI_ListClasses = new cGUI_2ClassesSelection();
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
{
GUI_ListClasses.PanelRight_IsCheckBoxes = true;
}
if (GUI_ListClasses.Run(this.GlobalInfo).IsSucceed == false) return;
cExtendedTable ListClassSelected = GUI_ListClasses.GetOutPut();
int IdxClassNeg = -1;
int IdxClassPos = -1;
for (int IdxC = 0; IdxC < ListClassSelected[0].Count; IdxC++)
{
if (ListClassSelected[0][IdxC] == 1) IdxClassNeg = IdxC;
if (ListClassSelected[1][IdxC] == 1) IdxClassPos = IdxC;
}
string SubTitle = "Z-Factor";
if (_QCZRobustItem.Checked)
SubTitle += " (Robust)";
#region Single plate
cDesignerTab DT = new cDesignerTab();
// cDesignerMultiChoices DT = new cDesignerMultiChoices();
if ((ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)/*||(ProcessModeEntireScreeningToolStripMenuItem.Checked)*/)
{
List<cPlate> ListPlatesToProcess = new List<cPlate>();
cPlate TmpPlate = cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate();
// foreach (cPlate TmpPlate in ListPlatesToProcess)
// GUI_ListClasses.Get
// ListClassSelected
List<int> ListCheckBoxes = new List<int>();
for (int i = 0; i < ListClassSelected[1].Count; i++)
{
if (ListClassSelected[1][i] > 0)
ListCheckBoxes.Add(i);
}
for (int IdxClassSelected = 0; IdxClassSelected < ListCheckBoxes.Count; IdxClassSelected++)
{
cListWells ListWellsToProcess1 = new cListWells(null);
cListWells ListWellsToProcess2 = new cListWells(null);
int CurrentClassTobeProcessed = ListCheckBoxes[IdxClassSelected];
foreach (cWell item in TmpPlate.ListActiveWells)
{
if (item.GetCurrentClassIdx() != -1)
{
if (ListClassSelected[0][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess1.Add(item);
if (item.GetCurrentClassIdx() == CurrentClassTobeProcessed)
// if (ListClassSelected[1][ListCheckBoxes[IdxClassSelected]] == 1)
ListWellsToProcess2.Add(item);
}
}
cExtendedTable NewTable1 = new cExtendedTable(ListWellsToProcess1, true);
cExtendedTable NewTable2 = new cExtendedTable(ListWellsToProcess2, true);
if ((NewTable1.Count == 0) || (NewTable1[0].Count < 2) || (NewTable2.Count == 0) || (NewTable2[0].Count < 2))
{
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
{
MessageBox.Show("Insufficient number of control wells", "Error", MessageBoxButtons.OK, MessageBoxIcon.Error);
return;
}
//else
// continue;
}
cExtendedList ListZ = new cExtendedList();
List<cDescriptorType> ListDescForZFactor = new List<cDescriptorType>();
List<string> ListNames = new List<string>();
int RealIdx = 0;
for (int IDxDesc = 0; IDxDesc < cGlobalInfo.CurrentScreening.ListDescriptors.Count; IDxDesc++)
{
if (!cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc].IsActive()) continue;
cExtendedTable TableForZ = new cExtendedTable();
TableForZ.Add(NewTable1[RealIdx]);
TableForZ.Add(NewTable2[RealIdx]);
RealIdx++;
cZFactor ZF = new cZFactor();
ZF.SetInputData(TableForZ);
ZF.IsRobust = _QCZRobustItem.Checked;
ZF.Run();
ListZ.Add(ZF.GetOutPut()[0][1]);
ListDescForZFactor.Add(cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc]);
}
cExtendedTable ET = new cExtendedTable(new cExtendedTable(ListZ));
ET[0].ListTags = new List<object>();
ET[0].ListTags.AddRange(ListDescForZFactor);
ET.Name = TmpPlate.GetName() + "\n" + SubTitle + " - " + cGlobalInfo.ListWellClasses[IdxClassNeg].Name + " (" + NewTable1[0].Count + " wells) vs. " + cGlobalInfo.ListWellClasses[CurrentClassTobeProcessed].Name + " (" + NewTable2[0].Count + " wells)";
ET[0].Name = ET.Name;
cSort S = new cSort();
S.SetInputData(ET);
S.ColumnIndexForSorting = 0;
S.Run();
//ZFactorList.Sort(delegate(cSimpleSignature p1, cSimpleSignature p2) { return p1.AverageValue.CompareTo(p2.AverageValue); });
cViewerGraph1D VG1 = new cViewerGraph1D();
VG1.SetInputData(S.GetOutPut());
VG1.Chart.LabelAxisY = SubTitle;
VG1.Chart.LabelAxisX = "Descriptor";
VG1.Chart.IsZoomableX = true;
VG1.Chart.IsBar = true;
VG1.Chart.IsBorder = true;
VG1.Chart.IsDisplayValues = true;
VG1.Chart.IsShadow = true;
VG1.Chart.MarkerSize = 4;
VG1.Chart.DefaultAxisYMax = new cExtendedList();
VG1.Chart.DefaultAxisYMax.Add(1);
if (!cGlobalInfo.OptionsWindow.FFAllOptions.checkBoxZscoreMinValueAutomated.Checked)
{
VG1.Chart.DefaultAxisYMin = new cExtendedList();
VG1.Chart.DefaultAxisYMin.Add((double)cGlobalInfo.OptionsWindow.FFAllOptions.numericUpDownZscoreMinValue.Value);
}
VG1.Title = TmpPlate.GetName();
Classes.Base_Classes.General.cLineHorizontalForGraph VLZ05 = new Classes.Base_Classes.General.cLineHorizontalForGraph(.5);
VLZ05.IsAllowMoving = true;
VG1.Chart.ListHorizontalLines.Add(VLZ05);
VG1.Run();
cDesignerSplitter DS = new cDesignerSplitter();
DS.Orientation = Orientation.Vertical;
DS.SetInputData(VG1.GetOutPut());
cSort S1 = new cSort();
S1.SetInputData(ET);
S1.ColumnIndexForSorting = 0;
S1.IsAscending = false;
S1.Run();
cViewerTable VT = new cViewerTable();
VT.SetInputData(S1.GetOutPut());
VT.Run();
DS.SetInputData(VT.GetOutPut());
DS.Title = cGlobalInfo.ListWellClasses[IdxClassNeg].Name + " vs. " + cGlobalInfo.ListWellClasses[CurrentClassTobeProcessed].Name;
DS.Run();
DT.SetInputData(DS.GetOutPut());
}
DT.Run();
cDisplayToWindow CDW = new cDisplayToWindow();
CDW.SetInputData(DT.GetOutPut());//VG1.GetOutPut());
CDW.Title = SubTitle + " - " + TmpPlate.GetName();
CDW.Run();
CDW.Display();
}
#endregion
#region plate by plate
DT = new cDesignerTab();
// cDesignerMultiChoices DT = new cDesignerMultiChoices();
if ((ProcessModeplateByPlateToolStripMenuItem.Checked)/*||(ProcessModeEntireScreeningToolStripMenuItem.Checked)*/)
{
List<cPlate> ListPlatesToProcess = new List<cPlate>();
if ((ProcessModeplateByPlateToolStripMenuItem.Checked)/*||(ProcessModeEntireScreeningToolStripMenuItem.Checked)*/)
{
foreach (cPlate TmpPlate in cGlobalInfo.CurrentScreening.ListPlatesActive)
ListPlatesToProcess.Add(TmpPlate);
}
foreach (cPlate TmpPlate in ListPlatesToProcess)
{
cListWells ListWellsToProcess1 = new cListWells(null);
cListWells ListWellsToProcess2 = new cListWells(null);
foreach (cWell item in TmpPlate.ListActiveWells)
{
if (item.GetCurrentClassIdx() != -1)
{
if (ListClassSelected[0][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess1.Add(item);
if (ListClassSelected[1][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess2.Add(item);
}
}
cExtendedTable NewTable1 = new cExtendedTable(ListWellsToProcess1, true);
cExtendedTable NewTable2 = new cExtendedTable(ListWellsToProcess2, true);
if ((NewTable1.Count == 0) || (NewTable1[0].Count < 2) || (NewTable2.Count == 0) || (NewTable2[0].Count < 2))
{
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
{
MessageBox.Show("Insufficient number of control wells", "Error", MessageBoxButtons.OK, MessageBoxIcon.Error);
return;
}
else
continue;
}
cExtendedList ListZ = new cExtendedList();
List<cDescriptorType> ListDescForZFactor = new List<cDescriptorType>();
List<string> ListNames = new List<string>();
int RealIdx = 0;
for (int IDxDesc = 0; IDxDesc < cGlobalInfo.CurrentScreening.ListDescriptors.Count; IDxDesc++)
{
if (!cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc].IsActive()) continue;
cExtendedTable TableForZ = new cExtendedTable();
TableForZ.Add(NewTable1[RealIdx]);
TableForZ.Add(NewTable2[RealIdx]);
RealIdx++;
cZFactor ZF = new cZFactor();
ZF.SetInputData(TableForZ);
ZF.IsRobust = _QCZRobustItem.Checked;
ZF.Run();
ListZ.Add(ZF.GetOutPut()[0][1]);
ListDescForZFactor.Add(cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc]);
}
cExtendedTable ET = new cExtendedTable(new cExtendedTable(ListZ));
ET[0].ListTags = new List<object>();
ET[0].ListTags.AddRange(ListDescForZFactor);
ET.Name = TmpPlate.GetName() + "\n" + SubTitle + " - " + cGlobalInfo.ListWellClasses[IdxClassNeg].Name + " (" + NewTable1[0].Count + " wells) vs. " + cGlobalInfo.ListWellClasses[IdxClassPos].Name + " (" + NewTable2[0].Count + " wells)";
ET[0].Name = ET.Name;
cSort S = new cSort();
S.SetInputData(ET);
S.ColumnIndexForSorting = 0;
S.Run();
//ZFactorList.Sort(delegate(cSimpleSignature p1, cSimpleSignature p2) { return p1.AverageValue.CompareTo(p2.AverageValue); });
cViewerGraph1D VG1 = new cViewerGraph1D();
VG1.SetInputData(S.GetOutPut());
VG1.Chart.LabelAxisY = SubTitle;
VG1.Chart.LabelAxisX = "Descriptor";
VG1.Chart.IsZoomableX = true;
VG1.Chart.IsBar = true;
VG1.Chart.IsBorder = true;
VG1.Chart.IsDisplayValues = true;
VG1.Chart.IsShadow = true;
VG1.Chart.MarkerSize = 4;
VG1.Chart.DefaultAxisYMax = new cExtendedList();
VG1.Chart.DefaultAxisYMax.Add(1);
if (!cGlobalInfo.OptionsWindow.FFAllOptions.checkBoxZscoreMinValueAutomated.Checked)
{
VG1.Chart.DefaultAxisYMin = new cExtendedList();
VG1.Chart.DefaultAxisYMin.Add((double)cGlobalInfo.OptionsWindow.FFAllOptions.numericUpDownZscoreMinValue.Value);
}
VG1.Title = TmpPlate.GetName();
Classes.Base_Classes.General.cLineHorizontalForGraph VLZ05 = new Classes.Base_Classes.General.cLineHorizontalForGraph(.5);
VLZ05.IsAllowMoving = true;
VG1.Chart.ListHorizontalLines.Add(VLZ05);
VG1.Run();
cDesignerSplitter DS = new cDesignerSplitter();
DS.Orientation = Orientation.Vertical;
DS.SetInputData(VG1.GetOutPut());
cSort S1 = new cSort();
S1.SetInputData(ET);
S1.ColumnIndexForSorting = 0;
S1.IsAscending = false;
S1.Run();
cViewerTable VT = new cViewerTable();
VT.SetInputData(S1.GetOutPut());
VT.Run();
DS.SetInputData(VT.GetOutPut());
DS.Title = TmpPlate.GetName();
DS.Run();
DT.SetInputData(DS.GetOutPut());
}
DT.Run();
cDisplayToWindow CDW = new cDisplayToWindow();
CDW.SetInputData(DT.GetOutPut());//VG1.GetOutPut());
CDW.Title = SubTitle + " - " + ListPlatesToProcess.Count + " plates";
CDW.Run();
CDW.Display();
}
#endregion
#region entire screening
else if (ProcessModeEntireScreeningToolStripMenuItem.Checked)
{
List<cPlate> ListPlatesToProcess = new List<cPlate>();
foreach (cPlate TmpPlate in cGlobalInfo.CurrentScreening.ListPlatesActive)
ListPlatesToProcess.Add(TmpPlate);
cExtendedList ListZ = new cExtendedList();
List<cPlate> ListPlatesForZFactor = new List<cPlate>();
foreach (cPlate TmpPlate in ListPlatesToProcess)
{
cListWells ListWellsToProcess1 = new cListWells(null);
cListWells ListWellsToProcess2 = new cListWells(null);
foreach (cWell item in TmpPlate.ListActiveWells)
{
if (item.GetCurrentClassIdx() != -1)
{
if (ListClassSelected[0][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess1.Add(item);
if (ListClassSelected[1][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess2.Add(item);
}
}
cExtendedTable NewTable1 = new cExtendedTable(ListWellsToProcess1, cGlobalInfo.CurrentScreening.ListDescriptors.GetDescriptorIndex(cGlobalInfo.CurrentScreening.ListDescriptors.GetActiveDescriptor()));
cExtendedTable NewTable2 = new cExtendedTable(ListWellsToProcess2, cGlobalInfo.CurrentScreening.ListDescriptors.GetDescriptorIndex(cGlobalInfo.CurrentScreening.ListDescriptors.GetActiveDescriptor()));
//cExtendedTable NewTable2 = new cExtendedTable(ListWellsToProcess2, false);
if ((NewTable1.Count == 0) || (NewTable1[0].Count < 2) || (NewTable2.Count == 0) || (NewTable2[0].Count < 2))
{
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
{
MessageBox.Show("Insufficient number of control wells", "Error", MessageBoxButtons.OK, MessageBoxIcon.Error);
return;
}
else
continue;
}
cExtendedTable TableForZ = new cExtendedTable();
TableForZ.Add(NewTable1[0]);
TableForZ.Add(NewTable2[0]);
cZFactor ZF = new cZFactor();
ZF.IsRobust = _QCZRobustItem.Checked;
ZF.SetInputData(TableForZ);
ZF.Run();
double Zfactor = ZF.GetOutPut()[0][1];
ListZ.Add(Zfactor);
// update plate quality
TmpPlate.ListProperties.UpdateValueByName("Quality", Math.Exp(Zfactor - 1));
cProperty Prop = TmpPlate.ListProperties.FindByName("Quality");
Prop.Info = ZF.GetInfo();
ListPlatesForZFactor.Add(TmpPlate);
}
cExtendedTable ET = new cExtendedTable(new cExtendedTable(ListZ));
ET[0].ListTags = new List<object>();
ET[0].ListTags.AddRange(ListPlatesForZFactor);
ET.Name = SubTitle + " - " + cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName() + " - " + cGlobalInfo.ListWellClasses[IdxClassNeg].Name + /*" (" + NewTable1[0].Count + " wells)*/ " vs. " + cGlobalInfo.ListWellClasses[IdxClassPos].Name;// +" (" + NewTable2[0].Count + " wells)";
ET[0].Name = ET.Name;
cViewerGraph1D VG1 = new cViewerGraph1D();
VG1.SetInputData(ET);
VG1.Chart.LabelAxisY = SubTitle;
VG1.Chart.LabelAxisX = "Plate";
VG1.Chart.IsZoomableX = true;
VG1.Chart.IsBar = true;
VG1.Chart.IsBorder = true;
VG1.Chart.IsDisplayValues = true;
VG1.Chart.IsShadow = true;
VG1.Chart.MarkerSize = 4;
VG1.Chart.DefaultAxisYMax = new cExtendedList();
VG1.Chart.DefaultAxisYMax.Add(1);
if (!cGlobalInfo.OptionsWindow.FFAllOptions.checkBoxZscoreMinValueAutomated.Checked)
{
VG1.Chart.DefaultAxisYMin = new cExtendedList();
VG1.Chart.DefaultAxisYMin.Add((double)cGlobalInfo.OptionsWindow.FFAllOptions.numericUpDownZscoreMinValue.Value);
}
Classes.Base_Classes.General.cLineHorizontalForGraph VLZ05 = new Classes.Base_Classes.General.cLineHorizontalForGraph(.5);
VLZ05.IsAllowMoving = true;
VG1.Chart.ListHorizontalLines.Add(VLZ05);
VG1.Title = cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();
VG1.Run();
cDisplayToWindow CDW = new cDisplayToWindow();
CDW.SetInputData(VG1.GetOutPut());
CDW.Title = SubTitle + " - " + ListPlatesToProcess.Count + " plates";
CDW.Run();
CDW.Display();
#endregion
}
}
private void statisticsToolStripMenuItem1_Click_1(object sender, EventArgs e)
{
string NameFunction = "";
if (_StatCVItem.Checked)
NameFunction = "Coeff. of Variation";
else if (_StatMeanItem.Checked)
NameFunction = "Mean";
else if (_StatSumItem.Checked)
NameFunction = "Sum";
else if (_StatJarqueBeraItem.Checked)
NameFunction = "Jarque-Bera";
cGUI_ListClasses GUI_ListClasses = new cGUI_ListClasses();
GUI_ListClasses.IsCheckBoxes = true;
GUI_ListClasses.IsSelectAll = true;
if (GUI_ListClasses.Run().IsSucceed == false) return;
cExtendedTable ListClassSelected = new cExtendedTable(GUI_ListClasses.GetOutPut());// GetOutPut();
int IdxClass = -1;
for (int IdxC = 0; IdxC < ListClassSelected[0].Count; IdxC++)
{
if (ListClassSelected[0][IdxC] == 1) IdxClass = IdxC;
}
#region single plate and plate by plate
cDesignerTab DT = new cDesignerTab();
if ((ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked) || (ProcessModeplateByPlateToolStripMenuItem.Checked)/*||(ProcessModeEntireScreeningToolStripMenuItem.Checked)*/)
{
List<cPlate> ListPlatesToProcess = new List<cPlate>();
if ((ProcessModeplateByPlateToolStripMenuItem.Checked)/*||(ProcessModeEntireScreeningToolStripMenuItem.Checked)*/)
{
foreach (cPlate TmpPlate in cGlobalInfo.CurrentScreening.ListPlatesActive)
ListPlatesToProcess.Add(TmpPlate);
}
else
ListPlatesToProcess.Add(cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate());
foreach (cPlate TmpPlate in ListPlatesToProcess)
{
cListWells ListWellsToProcess1 = new cListWells(null);
foreach (cWell item in TmpPlate.ListActiveWells)
{
if (item.GetCurrentClassIdx() != -1)
{
if (ListClassSelected[0][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess1.Add(item);
}
}
cExtendedTable NewTable1 = new cExtendedTable(ListWellsToProcess1, true);
if ((NewTable1.Count == 0) || (NewTable1[0].Count < 3))
{
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
{
MessageBox.Show("Insufficient number of control wells", "Error", MessageBoxButtons.OK, MessageBoxIcon.Error);
return;
}
else
continue;
}
cExtendedList ListValues = new cExtendedList();
List<cDescriptorType> ListDescs = new List<cDescriptorType>();
List<string> ListNames = new List<string>();
int RealIdx = 0;
for (int IDxDesc = 0; IDxDesc < cGlobalInfo.CurrentScreening.ListDescriptors.Count; IDxDesc++)
{
if (!cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc].IsActive()) continue;
cExtendedTable TableForValues = new cExtendedTable();
TableForValues.Add(NewTable1[RealIdx]);
RealIdx++;
if (_StatJarqueBeraItem.Checked)
{
cNormalityJarqueBera JB = new cNormalityJarqueBera();
JB.SetInputData(TableForValues);
JB.Run();
ListValues.Add(JB.GetOutPut()[0][0]);
}
else
{
cStatistics CS = new cStatistics();
CS.UnselectAll();
if (_StatCVItem.Checked)
CS.IsCV = true;
else if (_StatMeanItem.Checked)
CS.IsMean = true;
else if (_StatSumItem.Checked)
CS.IsSum = true;
CS.SetInputData(TableForValues);
CS.Run();
ListValues.Add(CS.GetOutPut()[0][0]);
}
ListDescs.Add(cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc]);
}
cExtendedTable ET = new cExtendedTable(new cExtendedTable(ListValues));
ET[0].ListTags = new List<object>();
ET[0].ListTags.AddRange(ListDescs);
ET.Name = TmpPlate.GetName() + "\n" + NameFunction + " - " + cGlobalInfo.ListWellClasses[IdxClass].Name + " (" + NewTable1[0].Count + " wells)";
ET[0].Name = ET.Name;
cSort S = new cSort();
S.SetInputData(ET);
S.ColumnIndexForSorting = 0;
S.Run();
//ZFactorList.Sort(delegate(cSimpleSignature p1, cSimpleSignature p2) { return p1.AverageValue.CompareTo(p2.AverageValue); });
cViewerGraph1D VG1 = new cViewerGraph1D();
VG1.SetInputData(S.GetOutPut());
VG1.Chart.LabelAxisY = NameFunction;
VG1.Chart.LabelAxisX = "Descriptor";
VG1.Chart.IsZoomableX = true;
VG1.Chart.IsBar = true;
VG1.Chart.IsBorder = true;
VG1.Chart.IsDisplayValues = true;
VG1.Chart.IsShadow = true;
VG1.Chart.MarkerSize = 4;
VG1.Title = TmpPlate.GetName();
VG1.Run();
DT.SetInputData(VG1.GetOutPut());
}
DT.Run();
cDisplayToWindow CDW = new cDisplayToWindow();
CDW.SetInputData(DT.GetOutPut());//VG1.GetOutPut());
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
CDW.Title = NameFunction + " - " + ListPlatesToProcess[0].GetName();
else
CDW.Title = NameFunction + " - " + ListPlatesToProcess.Count + " plates";
CDW.Run();
CDW.Display();
}
#endregion
#region entire screening
else if (ProcessModeEntireScreeningToolStripMenuItem.Checked)
{
List<cPlate> ListPlatesToProcess = new List<cPlate>();
foreach (cPlate TmpPlate in cGlobalInfo.CurrentScreening.ListPlatesActive)
ListPlatesToProcess.Add(TmpPlate);
cExtendedList ListZ = new cExtendedList();
List<cPlate> ListPlatesForZFactor = new List<cPlate>();
foreach (cPlate TmpPlate in ListPlatesToProcess)
{
cListWells ListWellsToProcess1 = new cListWells(null);
foreach (cWell item in TmpPlate.ListActiveWells)
{
if (item.GetCurrentClassIdx() != -1)
{
if (ListClassSelected[0][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess1.Add(item);
}
}
cExtendedTable NewTable1 = new cExtendedTable(ListWellsToProcess1, cGlobalInfo.CurrentScreening.ListDescriptors.GetDescriptorIndex(cGlobalInfo.CurrentScreening.ListDescriptors.GetActiveDescriptor()));
if ((NewTable1.Count == 0) || (NewTable1[0].Count < 3))
{
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
{
MessageBox.Show("Insufficient number of control wells", "Error", MessageBoxButtons.OK, MessageBoxIcon.Error);
return;
}
else
continue;
}
if (_StatJarqueBeraItem.Checked)
{
cNormalityJarqueBera JB = new cNormalityJarqueBera();
JB.SetInputData(NewTable1);
JB.Run();
ListZ.Add(JB.GetOutPut()[0][0]);
}
else
{
cStatistics CS = new cStatistics();
CS.UnselectAll();
if (_StatCVItem.Checked)
CS.IsCV = true;
else if (_StatMeanItem.Checked)
CS.IsMean = true;
else if (_StatSumItem.Checked)
CS.IsSum = true;
CS.SetInputData(NewTable1);
CS.Run();
ListZ.Add(CS.GetOutPut()[0][0]);
}
ListPlatesForZFactor.Add(TmpPlate);
}
#endregion
cExtendedTable ET = new cExtendedTable(new cExtendedTable(ListZ));
ET[0].ListTags = new List<object>();
ET[0].ListTags.AddRange(ListPlatesForZFactor);
ET.Name = NameFunction + " - " + cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();// +" - " +cGlobalInfo.ListWellClasses[IdxClassNeg].Name + " (" + NewTable1[0].Count + " wells) vs. " +cGlobalInfo.ListWellClasses[IdxClassPos].Name + " (" + NewTable2[0].Count + " wells)";
ET[0].Name = ET.Name;
cViewerGraph1D VG1 = new cViewerGraph1D();
VG1.SetInputData(ET);
VG1.Chart.LabelAxisY = NameFunction;
VG1.Chart.LabelAxisX = "Plate";
VG1.Chart.IsZoomableX = true;
VG1.Chart.IsBar = true;
VG1.Chart.IsBorder = true;
VG1.Chart.IsDisplayValues = true;
VG1.Chart.IsShadow = true;
VG1.Chart.MarkerSize = 4;
VG1.Title = cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();
VG1.Run();
cDisplayToWindow CDW = new cDisplayToWindow();
CDW.SetInputData(VG1.GetOutPut());
CDW.Title = NameFunction + " - " + ListPlatesToProcess.Count + " plates";
CDW.Run();
CDW.Display();
}
}
private void backgroundWorkerForCSVtoDB_RunWorkerCompleted(object sender, RunWorkerCompletedEventArgs e)
{
if (e.Error != null)
{
System.Windows.Forms.MessageBox.Show("Error while processing the data", "Error!", MessageBoxButtons.OK, MessageBoxIcon.Error);
}
else
{
// //FormForPlateDimensions PlateDim = new FormForPlateDimensions();
// //PlateDim.Text = "Load generated screening";
// //PlateDim.checkBoxAddCellNumber.Visible = true;
// //PlateDim.checkBoxIsOmitFirstColumn.Visible = true;
// //PlateDim.labelHisto.Visible = true;
// //PlateDim.numericUpDownHistoSize.Visible = true;
// //if (PlateDim.ShowDialog() != System.Windows.Forms.DialogResult.OK)
// // return;
// // LoadCellByCellDB(PlateDim, this.SelectedPath);
cDesignerSplitter DS = new cDesignerSplitter();
DS.Orientation = Orientation.Vertical;
cViewertext VT = new cViewertext();
VT.SetInputData(this.CompleteReportString);
VT.Run();
cViewerGraph1D VG1 = new cViewerGraph1D();
VG1.Chart.LabelAxisX = "Well Index";
VG1.Chart.LabelAxisY = "Number of objects";
VG1.Chart.IsLine = true;
VG1.Chart.IsZoomableX = true;
VG1.Chart.IsXGrid = true;
VG1.SetInputData(ReportTable);
VG1.Run();
DS.SetInputData(VT.GetOutPut());
DS.SetInputData(VG1.GetOutPut());
DS.Run();
cDisplayToWindow DTW = new cDisplayToWindow();
DTW.Title = "CSV->DB report";
DTW.IsModal = false;
DTW.SetInputData(DS.GetOutPut());
DTW.Run();
DTW.Display();
if (MessageBox.Show("Database successfully created.\nDo you want load it?", "Question !", MessageBoxButtons.YesNo, MessageBoxIcon.Question) == System.Windows.Forms.DialogResult.No)
return;
else
cGlobalInfo.WindowHCSAnalyzer.LoadDB(this.SelectedPath, false);
}
}
private void ToolStripMenuItem_ZFactor(object sender, EventArgs e)
{
cGUI_2ClassesSelection GUI_ListClasses = new cGUI_2ClassesSelection();
if (GUI_ListClasses.Run(this.GlobalInfo).IsSucceed == false) return;
cExtendedTable ListClassSelected = GUI_ListClasses.GetOutPut();
int IdxClassNeg = -1;
int IdxClassPos = -1;
for (int IdxC = 0; IdxC < ListClassSelected[0].Count; IdxC++)
{
if (ListClassSelected[0][IdxC] == 1) IdxClassNeg = IdxC;
if (ListClassSelected[1][IdxC] == 1) IdxClassPos = IdxC;
}
string SubTitle = "Z-Factor";
cListWells ListWellsToProcess1 = new cListWells(null);
cListWells ListWellsToProcess2 = new cListWells(null);
foreach (cWell item in cGlobalInfo.ListSelectedWell)
{
if (item.GetCurrentClassIdx() != -1)
{
if (ListClassSelected[0][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess1.Add(item);
if (ListClassSelected[1][item.GetCurrentClassIdx()] == 1)
ListWellsToProcess2.Add(item);
}
}
cExtendedTable NewTable1 = new cExtendedTable(ListWellsToProcess1, true);
cExtendedTable NewTable2 = new cExtendedTable(ListWellsToProcess2, true);
if ((NewTable1.Count == 0) || (NewTable1[0].Count < 2) || (NewTable2.Count == 0) || (NewTable2[0].Count < 2))
{
if (ProcessModeCurrentPlateOnlyToolStripMenuItem.Checked)
{
MessageBox.Show("Insufficient number of control wells", "Error", MessageBoxButtons.OK, MessageBoxIcon.Error);
return;
}
}
cExtendedList ListZ = new cExtendedList();
List<cDescriptorType> ListDescForZFactor = new List<cDescriptorType>();
List<string> ListNames = new List<string>();
int RealIdx = 0;
for (int IDxDesc = 0; IDxDesc < cGlobalInfo.CurrentScreening.ListDescriptors.Count; IDxDesc++)
{
if (!cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc].IsActive()) continue;
cExtendedTable TableForZ = new cExtendedTable();
TableForZ.Add(NewTable1[RealIdx]);
TableForZ.Add(NewTable2[RealIdx]);
RealIdx++;
cZFactor ZF = new cZFactor();
ZF.SetInputData(TableForZ);
ZF.IsRobust = _QCZRobustItem.Checked;
ZF.Run();
ListZ.Add(ZF.GetOutPut()[0][1]);
ListDescForZFactor.Add(cGlobalInfo.CurrentScreening.ListDescriptors[IDxDesc]);
}
cExtendedTable ET = new cExtendedTable(new cExtendedTable(ListZ));
ET[0].ListTags = new List<object>();
ET[0].ListTags.AddRange(ListDescForZFactor);
ET.Name = SubTitle + " - " + cGlobalInfo.ListWellClasses[IdxClassNeg].Name + " (" + NewTable1[0].Count + " wells) vs. " + cGlobalInfo.ListWellClasses[IdxClassPos].Name + " (" + NewTable2[0].Count + " wells)";
ET[0].Name = ET.Name;
cSort S = new cSort();
S.SetInputData(ET);
S.ColumnIndexForSorting = 0;
S.Run();
cViewerGraph1D VG1 = new cViewerGraph1D();
VG1.SetInputData(S.GetOutPut());
VG1.Chart.LabelAxisY = SubTitle;
VG1.Chart.LabelAxisX = "Descriptor";
VG1.Chart.IsZoomableX = true;
VG1.Chart.IsBar = true;
VG1.Chart.IsBorder = true;
VG1.Chart.IsDisplayValues = true;
VG1.Chart.IsShadow = true;
VG1.Chart.MarkerSize = 4;
VG1.Chart.DefaultAxisYMax = new cExtendedList();
VG1.Chart.DefaultAxisYMax.Add(1);
//VG1.Title = TmpPlate.Name;
Classes.Base_Classes.General.cLineHorizontalForGraph VLZ05 = new Classes.Base_Classes.General.cLineHorizontalForGraph(.5);
VLZ05.IsAllowMoving = true;
VG1.Chart.ListHorizontalLines.Add(VLZ05);
VG1.Run();
cDesignerSplitter DS = new cDesignerSplitter();
DS.Orientation = Orientation.Vertical;
DS.SetInputData(VG1.GetOutPut());
cSort S1 = new cSort();
S1.SetInputData(ET);
S1.ColumnIndexForSorting = 0;
S1.IsAscending = false;
S1.Run();
cViewerTable VT = new cViewerTable();
VT.SetInputData(S1.GetOutPut());
VT.Run();
DS.SetInputData(VT.GetOutPut());
DS.Run();
cDisplayToWindow CDW = new cDisplayToWindow();
CDW.SetInputData(DS.GetOutPut());//VG1.GetOutPut());
CDW.Title = "List Wells - Z Factor";
CDW.Run();
CDW.Display();
}
void Process()
{
cDesignerTab DT = new cDesignerTab();
for (int i = 0; i < this.Input.Count; i++)
{
cExtendedTable FinalTable = this.Input[i];
cCurveForGraph CFG = new cCurveForGraph();
CFG.SetInputData(FinalTable);
CFG.Run();
//cLinearRegression LR = new cLinearRegression();
//LR.SetInputData(FinalTable);
//LR.Run();
cSigmoidFitting SF = new cSigmoidFitting();
SF.SetInputData(FinalTable);
if (SF.Run().IsSucceed == false) continue;
// double Ratio = LR.GetOutPut()[0][LR.GetOutPut().Count - 1] / SF.GetOutPut()[0][SF.GetOutPut().Count - 1];
cExtendedTable Sigmoid = SF.GetFittedRawValues(CFG.GetListXValues());
FinalTable[0] = Sigmoid[1];
cDesignerSplitter DS = new cDesignerSplitter();
//cViewerTableAsRichText VT = new cViewerTableAsRichText();
cViewerTable VT = new cViewerTable();
VT.SetInputData(SF.GetOutPut());
VT.DigitNumber = -1;
VT.Run();
cViewerGraph1D VS1 = new cViewerGraph1D();
//VS1.SetInputData(/*new cExtendedTable(AN.GetOutPut()[1])*/FinalTable);
VS1.SetInputData(new cExtendedTable(Sigmoid[1]));
VS1.AddCurve(CFG);
VS1.Chart.X_AxisValues = Sigmoid[0];//DGS.GetOutPut()[0];
VS1.Chart.IsLogAxis = true;
VS1.Chart.IsLine = true;
VS1.Chart.IsShadow = true;
VS1.Chart.Opacity = 210;
VS1.Chart.LineWidth = 3;
//VS1.Chart.IsDisplayValues = true;
VS1.Chart.LabelAxisX = "Concentration";
VS1.Chart.LabelAxisY = "Readout";
VS1.Chart.XAxisFormatDigitNumber = -1;
VS1.Chart.IsZoomableX = true;
Classes.Base_Classes.General.cLineVerticalForGraph VLForEC50 = new Classes.Base_Classes.General.cLineVerticalForGraph(SF.GetOutPut()[0][2]);
VLForEC50.AddText("EC50: " + SF.GetOutPut()[0][2].ToString("e3")/* + "\nError Ratio:" + Ratio.ToString("N4")*/);
VS1.Chart.ListVerticalLines.Add(VLForEC50);
VS1.Chart.ArraySeriesInfo = new cSerieInfoDesign[FinalTable.Count];
for (int IdxCurve = 0; IdxCurve < FinalTable.Count; IdxCurve++)
{
cSerieInfoDesign TmpSerieInfo = new cSerieInfoDesign();
// TmpSerieInfo.color = GlobalInfo.ListCellularPhenotypes[IdxCurve % GlobalInfo.ListCellularPhenotypes.Count].ColourForDisplay;
TmpSerieInfo.markerStyle = MarkerStyle.Circle;
VS1.Chart.ArraySeriesInfo[IdxCurve] = TmpSerieInfo;
}
VS1.Run();
DS.SetInputData(VS1.GetOutPut());
DS.SetInputData(VT.GetOutPut());
DS.Orientation = Orientation.Horizontal;
DS.Title = "Noise Stdev" + i * 10;
DS.Run();
DT.SetInputData(DS.GetOutPut());
}
DT.Run();
cDisplayToWindow MyDisplay = new cDisplayToWindow();
MyDisplay.SetInputData(DT.GetOutPut());
MyDisplay.Title = this.Input.Name;
MyDisplay.Run();
MyDisplay.Display();
}
private void panelForPlate_MouseDown(object sender, MouseEventArgs e)
{
if (cGlobalInfo.CurrentScreening == null) return;
if (e.Button == System.Windows.Forms.MouseButtons.Left)
{
cGlobalInfo.CurrentScreening.ClientPosFirst.X = e.X;
cGlobalInfo.CurrentScreening.ClientPosFirst.Y = e.Y;
// if (GlobalInfo.WindowForDRCDesign.Visible) return;
Point locationOnForm = this.panelForPlate.FindForm().PointToClient(Control.MousePosition);
// int VertPos = locationOnForm.Y - 163;
// Make a note that we "have the mouse".
bHaveMouse = true;
// Store the "starting point" for this rubber-band rectangle.
cGlobalInfo.CurrentScreening.ptOriginal.X = locationOnForm.X;// e.X + this.panelForPlate.Location.X/* + 10*/;
cGlobalInfo.CurrentScreening.ptOriginal.Y = locationOnForm.Y;// e.Y + this.panelForPlate.Location.Y/* + 76*/;
// Special value lets us know that no previous
// rectangle needs to be erased.
cGlobalInfo.CurrentScreening.ptLast.X = -1;
cGlobalInfo.CurrentScreening.ptLast.Y = -1;
}
else if (e.Button == System.Windows.Forms.MouseButtons.Right)
{
int ScrollShiftY = this.panelForPlate.VerticalScroll.Value;
int ScrollShiftX = this.panelForPlate.HorizontalScroll.Value;
int Gutter = (int)cGlobalInfo.OptionsWindow.FFAllOptions.numericUpDownGutter.Value;
int PosX = (int)((e.X - ScrollShiftX) / (cGlobalInfo.SizeHistoWidth + Gutter));
int PosY = (int)((e.Y - ScrollShiftY) / (cGlobalInfo.SizeHistoHeight + Gutter));
bool OnlyOnSelected = false;
cExtendedList cExL = new cExtendedList();
List<string> Names = new List<string>();
string CurrentName = "";
#region Display plate heat map
if ((PosX == 0) && (PosY == 0))
{
cListWells ListWellsToProcess = new cListWells(null);
foreach (cWell item in cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate().ListActiveWells)
if (item.GetCurrentClassIdx() != -1) ListWellsToProcess.Add(item);
cDesignerTab DT = new cDesignerTab();
for (int IdxDesc = 0; IdxDesc < cGlobalInfo.CurrentScreening.ListDescriptors.Count; IdxDesc++)
{
if (!cGlobalInfo.CurrentScreening.ListDescriptors[IdxDesc].IsActive()) continue;
bool IsMissing;
cExtendedTable NewTable = null;
if (!checkBoxDisplayClasses.Checked)
NewTable = new cExtendedTable(cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate().GetAverageValueDescTable(IdxDesc, out IsMissing));
else
NewTable = new cExtendedTable(cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate().GetWellClassesTable());
foreach (var item in NewTable)
item.ListTags = new List<object>();
for (int i = 0; i < cGlobalInfo.CurrentScreening.Columns; i++)
for (int j = 0; j < cGlobalInfo.CurrentScreening.Rows; j++)
{
cWell currentWell = cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate().GetWell(i, cGlobalInfo.CurrentScreening.Rows - j - 1, true);
NewTable[i].ListTags.Add(currentWell);
}
for (int IdxCol = 0; IdxCol < NewTable.Count; IdxCol++)
NewTable[IdxCol].Name = "Column " + (IdxCol + 1);
List<string> ListRow = new List<string>();
for (int IdxRow = 0; IdxRow < NewTable[0].Count; IdxRow++)
ListRow.Add("Row " + (NewTable[0].Count - IdxRow));
NewTable.ListRowNames = ListRow;
if (!checkBoxDisplayClasses.Checked)
NewTable.Name = cGlobalInfo.CurrentScreening.ListDescriptors[IdxDesc].GetName() + " (" + ListWellsToProcess.Count + " wells)";
else
NewTable.Name = cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate().GetName() + " - Well Associated Classes (" + ListWellsToProcess.Count + " wells)";
cViewerHeatMap VHM = new cViewerHeatMap();
VHM.SetInputData(NewTable);
VHM.GlobalInfo = GlobalInfo;
VHM.IsDisplayValues = false;
if (!checkBoxDisplayClasses.Checked)
VHM.Title = cGlobalInfo.CurrentScreening.ListDescriptors[IdxDesc].GetName() + " (" + ListWellsToProcess.Count + " wells)";
else
{
//VHM.ChartToBeIncluded
VHM.CurrentLUT = cGlobalInfo.ListWellClasses.BuildLUT();
VHM.IsAutomatedMinMax = false;
VHM.Min = 0;
VHM.Max = cGlobalInfo.ListWellClasses.Count - 1;
VHM.IsWellClassLegend = true;
VHM.Title = cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate().GetName() + " - Well Associated Classes (" + ListWellsToProcess.Count + " wells)";
}
VHM.Run();
DT.SetInputData(VHM.GetOutPut());
if (checkBoxDisplayClasses.Checked) break;
}
DT.Run();
cDisplayToWindow DWForPlate = new cDisplayToWindow();
DWForPlate.SetInputData(DT.GetOutPut());
DWForPlate.Run();
DWForPlate.Display();
return;
}
#endregion
#region Display column or row graphs
else if ((PosX == 0) && (PosY > 0))
{
cExL.ListTags = new List<object>();
for (int col = 0; col < cGlobalInfo.CurrentScreening.Columns; col++)
{
cPlate CurrentPlateToProcess = cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate();
cWell TmpWell = CurrentPlateToProcess.GetWell(col, PosY - 1, OnlyOnSelected);
if (TmpWell == null) continue;
cExL.ListTags.Add(TmpWell);
cExL.Add(TmpWell.ListSignatures[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetValue());
Names.Add("Column " + col);
}
CurrentName = "Row " + PosY;
}
else if ((PosY == 0) && (PosX > 0))
{
cExL.ListTags = new List<object>();
for (int row = 0; row < cGlobalInfo.CurrentScreening.Rows; row++)
{
cPlate CurrentPlateToProcess = cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate();
cWell TmpWell = CurrentPlateToProcess.GetWell(PosX - 1, row, OnlyOnSelected);
if (TmpWell == null) continue;
cExL.ListTags.Add(TmpWell);
cExL.Add(TmpWell.ListSignatures[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetValue());
Names.Add("Row " + row);
}
CurrentName = "Column " + PosX;
}
#endregion
else
{
ContextMenuStrip NewMenu = new ContextMenuStrip();
NewMenu.Items.Add(cGlobalInfo.CurrentScreening.GetExtendedContextMenu());
NewMenu.Items.Add(cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate().GetExtendedContextMenu());
NewMenu.Show(Control.MousePosition);
return;
}
cExtendedTable cExT = new cExtendedTable(cExL);
cExT.ListRowNames = Names;
cExT.Name = CurrentName;
cExT[0].Name = CurrentName;
cViewerGraph1D CV = new cViewerGraph1D();
CV.Chart.IsSelectable = true;
CV.Chart.LabelAxisX = "Well Index";
CV.Chart.LabelAxisY = cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();
//V1D.Chart.BackgroundColor = Color.LightYellow;
CV.Chart.IsXGrid = true;
CV.Chart.IsLine = true;
CV.SetInputData(cExT);
cFeedBackMessage Mess = CV.Run();
if (!Mess.IsSucceed)
{
MessageBox.Show(Mess.Message, "Error", MessageBoxButtons.OK, MessageBoxIcon.Error);
return;
}
//cViewerGraph CV = new cViewerGraph();
//CV.SetInputData(cExT);
//CV.Run();
cDesignerSinglePanel CD = new cDesignerSinglePanel();
CD.SetInputData(CV.GetOutPut());
CD.Run();
cDisplayToWindow DW = new cDisplayToWindow();
DW.SetInputData(CD.GetOutPut());
DW.Run();
DW.Display();
// CV.Display();
}
}
void ToolStripMenuItem_DRCAnalysis_Click(object sender, EventArgs e)
{
List<cDescriptorType> ListSelectedDesc = new List<cDescriptorType>();// GlobalInfo.CurrentScreening.ListDescriptors.GetActiveDescriptors();
ListSelectedDesc.Add(cGlobalInfo.CurrentScreening.ListDescriptors.GetActiveDescriptor());
//if (GlobalInfo == null) GlobalInfo = cGlobalInfo.CurrentScreening.GlobalInfo;
//if (cGlobalInfo == null) return;
cDesignerMultiChoices DT = new cDesignerMultiChoices();
cExtendedTable TableForGeneralResuts = new cExtendedTable();
TableForGeneralResuts.Add(new cExtendedList("p-Value"));
TableForGeneralResuts.Add(new cExtendedList("EC50"));
TableForGeneralResuts.Add(new cExtendedList("Slope"));
TableForGeneralResuts.Add(new cExtendedList("Bottom"));
TableForGeneralResuts.Add(new cExtendedList("Top"));
TableForGeneralResuts.Add(new cExtendedList("Window"));
TableForGeneralResuts.Add(new cExtendedList("Area Under Curve"));
TableForGeneralResuts.ListRowNames = new List<string>();
TableForGeneralResuts.ListTags = new List<object>();
cDesignerSplitter MainSplitter = new cDesignerSplitter();
int IdxNode = 0;
cListListWells CurrentSelectedGroups = this.BuildListListWells();
foreach (cListWells TmpListWells in CurrentSelectedGroups)
{
// List<cDescriptorType> LType = new List<cDescriptorType>();
// LType.Add(ListSelectedDesc[i]);
cExtendedTable CompleteTable = TmpListWells.GetAverageDescriptorValues(ListSelectedDesc, true, false);
//cExtendedTable CompleteTable = GLP.GetOutPut();
cCurveForGraph CFG = new cCurveForGraph();
CFG.SetInputData(CompleteTable);
CFG.Run();
cSigmoidFitting SF = new cSigmoidFitting();
SF.SetInputData(CompleteTable);
if (SF.Run().IsSucceed == false) continue;
// double Ratio = LR.GetOutPut()[0][LR.GetOutPut().Count - 1] / SF.GetOutPut()[0][SF.GetOutPut().Count - 1];
cANOVA A = new cANOVA();
cExtendedTable NewTable = CFG.ListPtValues.Crop(0, CFG.ListPtValues.Count - 1, 1, CFG.ListPtValues[0].Count - 1);
A.SignificanceThreshold = 1E-11;
A.SetInputData(NewTable);
A.Run();
cExtendedTable Sigmoid = SF.GetFittedRawValues(CFG.GetListXValues());
CompleteTable[0] = Sigmoid[1];
CompleteTable[0].Name = ListSelectedDesc[0].GetName() + "\n" + Sigmoid[1].Name;
cDesignerSplitter DS = new cDesignerSplitter();
//cViewerTableAsRichText VT = new cViewerTableAsRichText();
cViewerTable VT = new cViewerTable();
cExtendedTable TableResults = SF.GetOutPut();
if ((A.GetOutPut() != null) && (A.GetOutPut().Count > 0))
{
TableResults[0].Add(A.GetOutPut()[0][0]);
TableResults[0].Add(A.GetOutPut()[0][1]);
TableResults.ListRowNames.Add("p-Value");
TableResults.ListRowNames.Add("Rejected?");
TableForGeneralResuts[0].Add(A.GetOutPut()[0][0]);
}
else
{
TableForGeneralResuts[0].Add(1);
}
TableResults.Name = TV.Nodes[IdxNode].Text;
TableResults[0].Name = "Fitting Parameters";
VT.SetInputData(TableResults);
VT.DigitNumber = -1;
VT.Run();
cViewerGraph1D VS1 = new cViewerGraph1D();
cExtendedTable MyTable = new cExtendedTable(Sigmoid[1]);
MyTable.Name = TmpListWells.Name;// TV.Nodes[IdxNode].Text;
VS1.SetInputData(MyTable);
VS1.AddCurve(CFG);
VS1.Chart.X_AxisValues = Sigmoid[0];
VS1.Chart.IsLogAxis = true;
VS1.Chart.IsLine = true;
VS1.Chart.IsShadow = false;
VS1.Chart.Opacity = 210;
VS1.Chart.LineWidth = 3;
VS1.Chart.MarkerSize = 8;
VS1.Chart.IsDisplayValues = cGlobalInfo.OptionsWindow.FFAllOptions.checkBoxDRCDisplayValues.Checked;
VS1.Chart.LabelAxisX = "Concentration";
VS1.Chart.LabelAxisY = CompleteTable[1].Name;
VS1.Chart.XAxisFormatDigitNumber = cGlobalInfo.OptionsWindow.FFAllOptions.GetDRCNumberOfDigit();
VS1.Chart.IsZoomableX = true;
Classes.Base_Classes.General.cLineVerticalForGraph VLForEC50 = new Classes.Base_Classes.General.cLineVerticalForGraph(SF.GetOutPut()[0][2]);
//VLForEC50.AddText("EC50: " + SF.GetOutPut()[0][2].ToString("e3")/* + "\nError Ratio:" + Ratio.ToString("N4")*/);
VS1.Chart.ListVerticalLines.Add(VLForEC50);
TableForGeneralResuts.ListRowNames.Add(TV.Nodes[IdxNode].Text);
TableForGeneralResuts.ListTags.Add((Chart)VS1.Chart);//ListSelectedDesc[0]);
//EC50
TableForGeneralResuts[1].Add(SF.GetOutPut()[0][2]);
// Slope
TableForGeneralResuts[2].Add(SF.GetOutPut()[0][3]);
// Bottom
TableForGeneralResuts[3].Add(SF.GetOutPut()[0][0]);
// Top
TableForGeneralResuts[4].Add(SF.GetOutPut()[0][1]);
// Window
double Window = SF.GetOutPut()[0][1] / SF.GetOutPut()[0][0];
TableForGeneralResuts[5].Add(Window);
TableForGeneralResuts[6].Add(SF.GetOutPut()[0][5]);
VS1.Chart.ArraySeriesInfo = new cSerieInfoDesign[CompleteTable.Count];
for (int IdxCurve = 0; IdxCurve < CompleteTable.Count; IdxCurve++)
{
cSerieInfoDesign TmpSerieInfo = new cSerieInfoDesign();
TmpSerieInfo.color = cGlobalInfo.ListCellularPhenotypes[IdxCurve % cGlobalInfo.ListCellularPhenotypes.Count].ColourForDisplay;
TmpSerieInfo.markerStyle = MarkerStyle.None;
VS1.Chart.ArraySeriesInfo[IdxCurve] = TmpSerieInfo;
}
VS1.Run();
DS.SetInputData(VS1.GetOutPut());
DS.SetInputData(VT.GetOutPut());
DS.Orientation = Orientation.Horizontal;
DS.Title = TV.Nodes[IdxNode++].Text; //TmpListWells.ti;// ListSelectedDesc[0].GetName();
DS.Run();
DT.SetInputData(DS.GetOutPut());
}
DT.Run();
cExtendedControl TextEC = DT.GetOutPut();
if (TextEC == null) return;
TextEC.Width = 0;
TextEC.Height = 0;
TextEC.Anchor = (System.Windows.Forms.AnchorStyles)(System.Windows.Forms.AnchorStyles.Top | System.Windows.Forms.AnchorStyles.Bottom
| System.Windows.Forms.AnchorStyles.Left | System.Windows.Forms.AnchorStyles.Right);
MainSplitter.SetInputData(TextEC);
string DRCsortingMethod = cGlobalInfo.OptionsWindow.FFAllOptions.comboBoxDRCSorting.SelectedItem.ToString();
//comboBoxDRCSorting
int IdxColSorting = 0;
cExtendedTable RT = TableForGeneralResuts;
switch (DRCsortingMethod)
{
case "ANOVA":
IdxColSorting = 0;
break;
case "EC50":
IdxColSorting = 1;
break;
case "Window":
IdxColSorting = 5;
break;
case "AUC":
IdxColSorting = 6;
break;
case "None":
IdxColSorting = -1;
break;
default:
break;
}
if (IdxColSorting != -1)
{
cSort S = new cSort();
S.ColumnIndexForSorting = IdxColSorting;
S.SetInputData(TableForGeneralResuts);
S.IsAscending = true;
S.Run();
RT = S.GetOutPut();
}
cViewerTable VTForEC50 = new cViewerTable();
RT.Name = cGlobalInfo.CurrentScreening.ListDescriptors.GetActiveDescriptor().GetName();
VTForEC50.SetInputData(RT);
VTForEC50.DigitNumber = -1;
VTForEC50.Run();
MainSplitter.SetInputData(VTForEC50.GetOutPut());
MainSplitter.Orientation = Orientation.Vertical;
MainSplitter.Run();
cDisplayToWindow DTW = new cDisplayToWindow();
DTW.SetInputData(MainSplitter.GetOutPut());
DTW.Title = "DRC analysis [" + cGlobalInfo.CurrentScreening.ListDescriptors.GetActiveDescriptor().GetName() + "]";
DTW.Run();
DTW.Display();
}
void ToolStripMenuItem_DRCAnalysisMultiDesc_Click(object sender, EventArgs e)
{
List<cDescriptorType> ListSelectedDescs = cGlobalInfo.CurrentScreening.ListDescriptors.GetActiveDescriptors();
cListListWells CurrentSelectedGroups = this.BuildListListWells();
#region select folder
var dlg1 = new Ionic.Utils.FolderBrowserDialogEx();
dlg1.Description = "Select the folder containing your databases.";
dlg1.ShowNewFolderButton = true;
dlg1.ShowEditBox = true;
dlg1.ShowFullPathInEditBox = true;
DialogResult result = dlg1.ShowDialog();
if (result != DialogResult.OK) return;
string Path = dlg1.SelectedPath;
if (Directory.Exists(Path) == false) return;
string FolderName = dlg1.SelectedPath;
#endregion
foreach (var item in ListSelectedDescs)
{
string TmpFolder = FolderName + "\\" + item.GetName();
Directory.CreateDirectory(TmpFolder);
int IdxNode = 0;
List<cDescriptorType> ListSelectedDesc = new List<cDescriptorType>();
ListSelectedDesc.Add(item);
cExtendedTable TableForGeneralResuts = new cExtendedTable();
TableForGeneralResuts.Add(new cExtendedList("p-Value"));
TableForGeneralResuts.Add(new cExtendedList("EC50"));
TableForGeneralResuts.Add(new cExtendedList("Slope"));
TableForGeneralResuts.Add(new cExtendedList("Bottom"));
TableForGeneralResuts.Add(new cExtendedList("Top"));
TableForGeneralResuts.Add(new cExtendedList("Window"));
TableForGeneralResuts.Add(new cExtendedList("Area Under Curve"));
TableForGeneralResuts.ListRowNames = new List<string>();
TableForGeneralResuts.ListTags = new List<object>();
foreach (cListWells TmpListWells in CurrentSelectedGroups)
{
// List<cDescriptorType> LType = new List<cDescriptorType>();
// LType.Add(ListSelectedDesc[i]);
cExtendedTable CompleteTable = TmpListWells.GetAverageDescriptorValues(ListSelectedDesc, true, false);
//cExtendedTable CompleteTable = GLP.GetOutPut();
cCurveForGraph CFG = new cCurveForGraph();
CFG.SetInputData(CompleteTable);
CFG.Run();
cSigmoidFitting SF = new cSigmoidFitting();
SF.SetInputData(CompleteTable);
if (SF.Run().IsSucceed == false) continue;
// double Ratio = LR.GetOutPut()[0][LR.GetOutPut().Count - 1] / SF.GetOutPut()[0][SF.GetOutPut().Count - 1];
cANOVA A = new cANOVA();
cExtendedTable NewTable = CFG.ListPtValues.Crop(0, CFG.ListPtValues.Count - 1, 1, CFG.ListPtValues[0].Count - 1);
A.SignificanceThreshold = 1E-11;
A.SetInputData(NewTable);
A.Run();
cExtendedTable Sigmoid = SF.GetFittedRawValues(CFG.GetListXValues());
CompleteTable[0] = Sigmoid[1];
CompleteTable[0].Name = ListSelectedDesc[0].GetName() + "\n" + Sigmoid[1].Name;
cDesignerSplitter DS = new cDesignerSplitter();
//cViewerTableAsRichText VT = new cViewerTableAsRichText();
cViewerTable VT = new cViewerTable();
cExtendedTable TableResults = SF.GetOutPut();
if ((A.GetOutPut() != null) && (A.GetOutPut().Count > 0))
{
TableResults[0].Add(A.GetOutPut()[0][0]);
TableResults[0].Add(A.GetOutPut()[0][1]);
TableResults.ListRowNames.Add("p-Value");
TableResults.ListRowNames.Add("Rejected?");
TableForGeneralResuts[0].Add(A.GetOutPut()[0][0]);
}
else
{
TableForGeneralResuts[0].Add(1);
}
TableResults.Name = TV.Nodes[IdxNode].Text;
TableResults[0].Name = "Fitting Parameters";
VT.SetInputData(TableResults);
VT.DigitNumber = -1;
VT.Run();
cViewerGraph1D VS1 = new cViewerGraph1D();
cExtendedTable MyTable = new cExtendedTable(Sigmoid[1]);
MyTable.Name = TmpListWells.Name;// TV.Nodes[IdxNode].Text;
VS1.SetInputData(MyTable);
VS1.AddCurve(CFG);
VS1.Chart.X_AxisValues = Sigmoid[0];
VS1.Chart.IsLogAxis = true;
VS1.Chart.IsLine = true;
VS1.Chart.IsShadow = false;
VS1.Chart.Opacity = 210;
VS1.Chart.LineWidth = 3;
VS1.Chart.MarkerSize = 8;
VS1.Chart.IsDisplayValues = cGlobalInfo.OptionsWindow.FFAllOptions.checkBoxDRCDisplayValues.Checked;
VS1.Chart.LabelAxisX = "Concentration";
VS1.Chart.LabelAxisY = CompleteTable[1].Name;
VS1.Chart.XAxisFormatDigitNumber = cGlobalInfo.OptionsWindow.FFAllOptions.GetDRCNumberOfDigit();
VS1.Chart.IsZoomableX = true;
Classes.Base_Classes.General.cLineVerticalForGraph VLForEC50 = new Classes.Base_Classes.General.cLineVerticalForGraph(SF.GetOutPut()[0][2]);
//VLForEC50.AddText("EC50: " + SF.GetOutPut()[0][2].ToString("e3")/* + "\nError Ratio:" + Ratio.ToString("N4")*/);
VS1.Chart.ListVerticalLines.Add(VLForEC50);
TableForGeneralResuts.ListRowNames.Add(TV.Nodes[IdxNode].Text);
TableForGeneralResuts.ListTags.Add((Chart)VS1.Chart);//ListSelectedDesc[0]);
//EC50
TableForGeneralResuts[1].Add(SF.GetOutPut()[0][2]);
// Slope
TableForGeneralResuts[2].Add(SF.GetOutPut()[0][3]);
// Bottom
TableForGeneralResuts[3].Add(SF.GetOutPut()[0][0]);
// Top
TableForGeneralResuts[4].Add(SF.GetOutPut()[0][1]);
// Window
double Window = SF.GetOutPut()[0][1] / SF.GetOutPut()[0][0];
TableForGeneralResuts[5].Add(Window);
TableForGeneralResuts[6].Add(SF.GetOutPut()[0][5]);
VS1.Chart.ArraySeriesInfo = new cSerieInfoDesign[CompleteTable.Count];
for (int IdxCurve = 0; IdxCurve < CompleteTable.Count; IdxCurve++)
{
cSerieInfoDesign TmpSerieInfo = new cSerieInfoDesign();
TmpSerieInfo.color = cGlobalInfo.ListCellularPhenotypes[IdxCurve % cGlobalInfo.ListCellularPhenotypes.Count].ColourForDisplay;
TmpSerieInfo.markerStyle = MarkerStyle.None;
VS1.Chart.ArraySeriesInfo[IdxCurve] = TmpSerieInfo;
}
VS1.Run();
//DS.SetInputData(VS1.GetOutPut());
//DS.SetInputData(VT.GetOutPut());
//DS.Orientation = Orientation.Horizontal;
//DS.Title = TV.Nodes[IdxNode++].Text; //TmpListWells.ti;// ListSelectedDesc[0].GetName();
//DS.Run();
IdxNode++;
// DT.SetInputData(DS.GetOutPut());
}
cTableToHTML THTML = new cTableToHTML();
TableForGeneralResuts.Name = item.GetName();
THTML.SetInputData(TableForGeneralResuts);
THTML.IsDisplayUIForFilePath = false;
THTML.FolderName = TmpFolder;
THTML.ListProperties.FindByName("Open HTML File ?").SetNewValue((bool)false);
THTML.ListProperties.FindByName("Open HTML File ?").IsGUIforValue = false;
THTML.Run();
}
System.Diagnostics.Process.Start(FolderName);
}
public cFeedBackMessage Run(cScreening CompleteScreening)
{
if (this.Input == null)
{
FeedBackMessage.IsSucceed = false;
FeedBackMessage.Message = "No input data defined.";
return FeedBackMessage;
}
bool IsCurrentDescOnly = false;
if (this.ListPlates == null)
ListPlates = CompleteScreening.ListPlatesActive;
cDisplayToWindow CDW1 = new cDisplayToWindow();
cDesignerTab DT = new cDesignerTab();
foreach (cDescriptorType CurrentDesc in CompleteScreening.ListDescriptors.GetActiveDescriptors())
{
cListExtendedTable CompleteListOfData = new cListExtendedTable();
cExtendedTable FullTableAverage = new cExtendedTable();
FullTableAverage.ListRowNames = new List<string>();
string TableName = CurrentDesc.GetName() + " evolution\n" + Input[0].Sum() + " classes - ";
for (int i = 0; i < Input[0].Count; i++)
{
if ((Input[0][i] == 1) && (Input[0].ListTags != null) && (Input[0].ListTags[i].GetType() == typeof(cWellClassType)))
{
cWellClassType TmpWellClass = (cWellClassType)Input[0].ListTags[i];
CompleteListOfData.Add(new cExtendedTable());
CompleteListOfData[CompleteListOfData.Count - 1].Name = TmpWellClass.Name;
CompleteListOfData[CompleteListOfData.Count - 1].Tag = Input[0].ListTags[i];
FullTableAverage.Add(new cExtendedList(TmpWellClass.Name));
FullTableAverage[FullTableAverage.Count - 1].ListTags = new List<object>();
FullTableAverage[FullTableAverage.Count - 1].Name = TmpWellClass.Name;
FullTableAverage[FullTableAverage.Count - 1].Tag = TmpWellClass;
int IdxPlate = 0;
foreach (cPlate TmpPlate in CompleteScreening.ListPlatesActive)
{
FullTableAverage[FullTableAverage.Count - 1].Add(0);
FullTableAverage[FullTableAverage.Count - 1].ListTags.Add(TmpWellClass);
CompleteListOfData[CompleteListOfData.Count - 1].Add(new cExtendedList(TmpPlate.GetName()));
CompleteListOfData[CompleteListOfData.Count - 1][CompleteListOfData[CompleteListOfData.Count - 1].Count - 1].Tag = TmpPlate;
CompleteListOfData[CompleteListOfData.Count - 1][CompleteListOfData[CompleteListOfData.Count - 1].Count - 1].Add(IdxPlate);
IdxPlate++;
}
}
}
TableName += FullTableAverage[0].Count + " plates";
FullTableAverage.Name = TableName;
foreach (cPlate TmpPlate in CompleteScreening.ListPlatesActive)
FullTableAverage.ListRowNames.Add(TmpPlate.GetName());
// cDescriptorsType CurrentDesc = CompleteScreening.ListDescriptors.GetActiveDescriptor();
int RealIdx = 0;
for (int i = 0; i < Input[0].Count; i++)
{
if (Input[0][i] == 1)
{
int IdxPlate = 0;
foreach (cPlate TmpPlate in ListPlates/*CompleteScreening.ListPlatesActive*/)
{
cExtendedList CurrentListValues = new cExtendedList();
foreach (cWell item in TmpPlate.ListActiveWells)
if ((item.GetCurrentClassIdx() != -1) && (item.GetCurrentClassIdx() == i))
{
double Value = item.ListSignatures.GetSignature(CurrentDesc).GetValue();
CurrentListValues.Add(Value);
CompleteListOfData[RealIdx][IdxPlate].Add(Value);
}
FullTableAverage[RealIdx][IdxPlate] = CurrentListValues.Mean();
IdxPlate++;
}
RealIdx++;
}
}
cViewerGraph1D VG = new cViewerGraph1D();
VG.Chart.IsLine = true;
VG.Chart.IsShadow = true;
VG.Chart.IsZoomableX = true;
// VG.Chart.IsYGrid = true;
//VG.Chart.IsDisplayValues = true;
VG.Chart.IsLegend = true;
//cViewerStackedHistogram CV1 = new cViewerStackedHistogram();
// CV1.SetInputData(NewTable);
VG.SetInputData(FullTableAverage);
VG.SetInputData(CompleteListOfData);
VG.Chart.LabelAxisX = "Plate";
VG.Chart.LabelAxisY = CurrentDesc.GetName();
VG.Run();
cExtendedControl TmpCtrl = VG.GetOutPut();
TmpCtrl.Title = CurrentDesc.GetName();
DT.SetInputData(TmpCtrl);
}
DT.Run();
CDW1.Title = "Descriptor Evolution";
CDW1.SetInputData(DT.GetOutPut());
CDW1.Run();
CDW1.Display();
return FeedBackMessage;
}
private void DisplayGraph(object sender, EventArgs e)
{
cViewerGraph1D VG = new cViewerGraph1D();
VG.Chart.IsLine = true;
VG.Chart.IsSelectable = false;
VG.Chart.IsZoomableX = true;
VG.Chart.IsLegend = true;
cExtendedTable CET = new cExtendedTable();
CET.Name = Input.Name;
CET.ListRowNames = new List<string>();
foreach (DataGridViewColumn item in GridView.SelectedColumns)
CET.Add(Input[item.Index]);
foreach (var item in this.Input.ListRowNames)
CET.ListRowNames.Add(item);
if (this.Input.ListTags != null)
{
CET.ListTags = new List<object>();
for (int i = 0; i < GridView.SelectedColumns.Count; i++)
CET[i].ListTags = new List<object>();
}
if(this.Input.ListTags!=null)
foreach (var item in this.Input.ListTags)
{
CET.ListTags.Add(item);
}
//for (int i = 0; i < GridView.SelectedColumns.Count; i++)
{
//if (this.Input[i].ListTags != null)
//{
// int NumTags= this.Input[i].ListTags.Count;
// for (int Idx = 0; Idx < NumTags; Idx++)
// {
// CET[i].ListTags.Add(this.Input[i].ListTags[Idx]);
// }
//}
//foreach (var item in this.Input[i].ListTags)
//CET[i].ListTags.Add(item);
}
VG.SetInputData(CET);
VG.Run();
cDesignerSinglePanel CD = new cDesignerSinglePanel();
CD.SetInputData(VG.GetOutPut());
CD.Run();
cDisplayToWindow DW = new cDisplayToWindow();
DW.Title = CET.Name + " - Graph Viewer";
DW.SetInputData(CD.GetOutPut());
DW.Run();
DW.Display();
}
public void Refresh1DScatter()
{
List<cWellClassType> ListWellClassesSelected = cGlobalInfo.ListWellClasses;
cViewerGraph1D V1D = new cViewerGraph1D();
V1D.Chart.IsSelectable = true;
V1D.Chart.LabelAxisX = "Well Index";
V1D.Chart.LabelAxisY = cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();
V1D.Chart.IsDetachable = false;
V1D.Chart.IsXGrid = true;
cExtendedList EtF = new cExtendedList();
for (int i = 0; i < cGlobalInfo.ListWellClasses.Count; i++)
{
EtF.Add(1);
}
cExtendedTable DataFromPlate = new cExtendedTable(cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate().ListActiveWells,
cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx, EtF);
DataFromPlate.Name = cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate().GetName();
V1D.Chart.IsShadow = true;
V1D.Chart.IsBorder = true;
//V1D.Chart.IsSelectable = true;
V1D.Chart.CurrentTitle.Tag = cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate();
V1D.SetInputData(DataFromPlate);
V1D.Run();
cDesignerSplitter DS = new cDesignerSplitter();
DS.Orientation = System.Windows.Forms.Orientation.Horizontal;
DS.SetInputData(V1D.GetOutPut());
cExtendedTable NewTable = cGlobalInfo.CurrentScreening.GetCurrentDisplayPlate().ListActiveWells.Filter(ListWellClassesSelected).GetAverageDescriptorValues(cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx);
NewTable.Name = "Histogram";
cViewerStackedHistogram CV1 = new cViewerStackedHistogram();
CV1.SetInputData(NewTable);
CV1.Chart.LabelAxisX = cGlobalInfo.CurrentScreening.ListDescriptors[cGlobalInfo.CurrentScreening.ListDescriptors.CurrentSelectedDescriptorIdx].GetName();
CV1.Run();
CV1.Chart.IsDetachable = false;
DS.SetInputData(CV1.GetOutPut());
DS.Run();
cGlobalInfo.WindowHCSAnalyzer.tabPage1DView.Controls.Clear();
DS.GetOutPut().Width = cGlobalInfo.WindowHCSAnalyzer.tabPage1DView.Width;
DS.GetOutPut().Height = cGlobalInfo.WindowHCSAnalyzer.tabPage1DView.Height;
DS.GetOutPut().Controls[0].Width = cGlobalInfo.WindowHCSAnalyzer.tabPage1DView.Width;
DS.GetOutPut().Controls[0].Height = cGlobalInfo.WindowHCSAnalyzer.tabPage1DView.Height;
cGlobalInfo.WindowHCSAnalyzer.tabPage1DView.Controls.Add(DS.GetOutPut());
}
