Esempio n. 1
0
        internal void Write(ushort chromIndex, NsaReader nsaReader)
        {
            if (nsaReader == null)
            {
                return;
            }

            var dataBlocks  = nsaReader.GetCompressedBlocks(chromIndex);
            var indexBlocks = nsaReader.GetIndexBlocks(chromIndex);

            var i = 0;//index of the index Blocks

            //cannot convert the dataBlocks into a list since that may take up GBs of memory (proportional to the nas file size)
            foreach (var dataBlock in dataBlocks)
            {
                if (i > indexBlocks.Count)
                {
                    throw new IndexOutOfRangeException("Nsa Index have less blocks than the Nsa file. They have to be the same.");
                }

                var oldIndexBlock = indexBlocks[i];
                _index.Add(chromIndex, oldIndexBlock.Start, oldIndexBlock.End, _writer.BaseStream.Position, oldIndexBlock.Length);
                dataBlock.WriteCompressedBytes(_writer);
                i++;
            }
            if (i < indexBlocks.Count)
            {
                throw new IndexOutOfRangeException("Nsa Index have more blocks than the Nsa file. They have to be the same.");
            }
        }
Esempio n. 2
0
        public void Query_chunks_in_same_chrom()
        {
            var stream  = new MemoryStream();
            var writer  = new ExtendedBinaryWriter(stream);
            var version = new DataSourceVersion("dbsnp", "150", DateTime.Now.Ticks, "dbsnp ids");
            var index   = new NsaIndex(writer, GenomeAssembly.GRCh37, version, "dbsnp", true, true, SaCommon.SchemaVersion, false);

            index.Add(0, 100, 2000, 23457, 89320);
            index.Add(0, 2100, 4000, 112778, 58746);
            index.Add(0, 4100, 7000, 171525, 658794);

            (long start, int chunkCount) = index.GetFileRange(0, 150, 2120);
            Assert.Equal(23457, start);
            Assert.Equal(2, chunkCount);

            (start, chunkCount) = index.GetFileRange(0, 50, 98);
            Assert.Equal(-1, start);
            Assert.Equal(0, chunkCount);

            (start, chunkCount) = index.GetFileRange(0, 150, 2010);
            Assert.Equal(23457, start);
            Assert.Equal(1, chunkCount);

            (start, chunkCount) = index.GetFileRange(0, 2010, 4050);
            Assert.Equal(112778, start);
            Assert.Equal(1, chunkCount);

            (start, chunkCount) = index.GetFileRange(0, 4010, 4050);
            Assert.Equal(-1, start);
            Assert.Equal(0, chunkCount);

            (start, chunkCount) = index.GetFileRange(0, 7010, 7050);
            Assert.Equal(-1, start);
            Assert.Equal(0, chunkCount);
        }