private void LoadMotif()
        {
            DialogResult dlg = dlgOpenMotif.ShowDialog();

            if (dlg != DialogResult.OK)
            {
                return;
            }
            SetText(dlgOpenMotif);
            string filename = dlgOpenMotif.FileName;

            try
            {
                Motif = Motif.ReadFromFile(filename);
            }
            catch
            {
                MessageBox.Show("The file may be corrupted or not a valid PeSA motif file.", Analyzer.ProgramName);
                return;
            }
            Validator = new MotifValidator();
            Settings settings    = Settings.Load("default.settings");
            int      heightImage = 200;
            int      widthImage  = 800;

            if (settings != null)
            {
                heightImage = settings.MotifHeight;
                widthImage  = settings.MotifWidth;
            }
            mdPositive.Image = Motif.GetPositiveMotif(widthImage, heightImage);
            mdNegative.Image = Motif.GetNegativeMotif(widthImage, heightImage);
            mdChart.Image    = Motif.GetBarChart(pMotif.Width - 6);
            eWildtype.Text   = Motif.WildTypePeptide;
        }
        private bool DrawMotifs()
        {
            try
            {
                ClearMotifs();
                if (PA == null)
                {
                    return(true);
                }
                Settings settings    = Settings.Load("default.settings");
                int      heightImage = 200;
                int      widthImage  = 800;
                if (settings != null)
                {
                    heightImage = settings.MotifHeight;
                    widthImage  = settings.MotifWidth;
                }
                Motif = new Motif(PA.NormalizedPeptideWeights, PA.NormalizedWildtypeWeights, PA.WildTypePeptide, PA.PositiveThreshold, PA.NegativeThreshold);

                mdPositive.Image = Motif.GetPositiveMotif(widthImage, heightImage);

                mdNegative.Image = Motif.GetNegativeMotif(widthImage, heightImage);

                mdChart.Image = Motif.GetBarChart(pMotif.Width - 6);
                return(true);
            }
            catch { return(false); }
        }
Esempio n. 3
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        private bool DrawMotifs()
        {
            try
            {
                ClearMotifs();
                if (OA == null)
                {
                    return(true);
                }
                Settings settings    = Settings.Load("default.settings");
                int      heightImage = 200;
                int      widthImage  = 800;
                if (settings != null)
                {
                    heightImage = settings.MotifHeight;
                    widthImage  = settings.MotifWidth;
                }
                if (!CreateMotif())
                {
                    return(false);
                }

                mdPositive.Image = Motif.GetPositiveMotif(widthImage, heightImage);

                mdNegative.Image = Motif.GetNegativeMotif(widthImage, heightImage);

                mdChart.Image = Motif.GetBarChart(pMotif.Width - 6);
                return(true);
            }
            catch { return(false); }
        }
Esempio n. 4
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        private void DisplayMotif()
        {
            if (Motif == null)
            {
                return;
            }

            Settings settings    = Settings.Load("default.settings");
            int      heightImage = 200;
            int      widthImage  = 800;

            if (settings != null)
            {
                heightImage = settings.MotifHeight;
                widthImage  = settings.MotifWidth;
            }
            if (Motif.PositiveColumns != null)
            {
                mdPositive.Image = Motif.GetPositiveMotif(widthImage, heightImage);
            }
            else if (Motif.Frequencies != null)
            {
                mdPositive.Image = Motif.GetFrequencyMotif(widthImage, heightImage);
            }
            else
            {
                mdPositive.Image = null;
            }
            if (Motif.NegativeColumns != null)
            {
                mdNegative.Image = Motif.GetNegativeMotif(widthImage, heightImage);
            }
            else
            {
                mdNegative.Visible = false;
                mdNegative.Image   = null;
            }
            if (Motif.PositiveColumns != null)
            {
                mdChart.Image = Motif.GetBarChart(pMotif.Width - 6);
            }
            else
            {
                mdChart.Visible = false;
            }

            ePositiveThreshold.Text = Motif.PositiveThreshold.ToString();
            toolTip1.SetToolTip(eScorerPosThreshold, string.Format("Range: [{0:N2}, {1:N2}]", Motif.PositiveThreshold, Motif.MaxPosWeight));
            eNegativeThreshold.Text = Motif.NegativeThreshold.ToString();
            toolTip1.SetToolTip(eScorerNegThreshold, string.Format("Range: [{0:N2}, {1:N2}]", 0, Motif.NegativeThreshold));
            eWildtype.Text        = Motif.WildTypePeptide;
            eTargetPosition.Text  = "";
            eTargetAminoAcid.Text = "";
        }
Esempio n. 5
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        private void LoadMotif()
        {
            DialogResult dlg = dlgOpenMotif.ShowDialog();

            if (dlg != DialogResult.OK)
            {
                return;
            }
            SetText(dlgOpenMotif);
            string filename = dlgOpenMotif.FileName;

            try
            {
                Motif = Motif.ReadFromFile(filename);
            }
            catch
            {
                MessageBox.Show("The file may be corrupted or not a valid PeSA motif file.", Analyzer.ProgramName);
            }
            Settings settings    = Settings.Load("default.settings");
            int      heightImage = 200;
            int      widthImage  = 800;

            if (settings != null)
            {
                heightImage = settings.MotifHeight;
                widthImage  = settings.MotifWidth;
            }
            mdPositive.Image        = Motif.GetPositiveMotif(widthImage, heightImage);
            mdNegative.Image        = Motif.GetNegativeMotif(widthImage, heightImage);
            mdChart.Image           = Motif.GetBarChart(pMotif.Width - 6);
            ePositiveThreshold.Text = Motif.PositiveThreshold.ToString();
            toolTip1.SetToolTip(eScorerPosThreshold, string.Format("Range: [{0:N2}, {1:N2}]", Motif.PositiveThreshold, Motif.MaxPosWeight));
            eNegativeThreshold.Text = Motif.NegativeThreshold.ToString();
            toolTip1.SetToolTip(eScorerNegThreshold, string.Format("Range: [{0:N2}, {1:N2}]", 0, Motif.NegativeThreshold));
            eWildtype.Text = Motif.WildTypePeptide;
            eTarget.Text   = "";
        }