public IAnnotatedPosition Annotate(IPosition position)
{
if (position == null)
{
return(null);
}
var annotatedVariants = GetAnnotatedVariants(position.Variants);
var annotatedPosition = new AnnotatedPosition(position, annotatedVariants);
if (annotatedPosition.AnnotatedVariants == null ||
annotatedPosition.AnnotatedVariants.Length == 0 ||
position.Chromosome.UcscName == "chrM" && !_annotateMito
)
{
return(annotatedPosition);
}
_sequenceProvider?.Annotate(annotatedPosition);
_saProviders?.Annotate(annotatedPosition);
_conservationProvider?.Annotate(annotatedPosition);
_taProvider.Annotate(annotatedPosition);
_plugins?.Annotate(annotatedPosition, _sequenceProvider?.Sequence);
TrackAffectedGenes(annotatedPosition);
return(annotatedPosition);
}
public IAnnotatedPosition Annotate(IPosition position)
{
if (position == null)
{
return(null);
}
var annotatedVariants = GetAnnotatedVariants(position.Variants);
var annotatedPosition = new AnnotatedPosition(position, annotatedVariants);
if (annotatedPosition.AnnotatedVariants == null ||
annotatedPosition.AnnotatedVariants.Length == 0 ||
position.Chromosome.UcscName == "chrM" && !_annotateMito
)
{
return(annotatedPosition);
}
_sequenceProvider?.Annotate(annotatedPosition);
_taProvider.Annotate(annotatedPosition);
return(annotatedPosition);
}