Esempio n. 1
0
        public void TestClusterWithCross()
        {
            // Create a list of Mum classes.
            List <MaxUniqueMatch> matches = new List <MaxUniqueMatch>();
            MaxUniqueMatch        match   = null;

            match = new MaxUniqueMatch();
            match.FirstSequenceStart  = 0;
            match.Length              = 4;
            match.SecondSequenceStart = 4;
            matches.Add(match);

            match = new MaxUniqueMatch();
            match.FirstSequenceStart  = 4;
            match.Length              = 3;
            match.SecondSequenceStart = 0;
            matches.Add(match);

            match = new MaxUniqueMatch();
            match.FirstSequenceStart  = 10;
            match.Length              = 3;
            match.SecondSequenceStart = 10;
            matches.Add(match);

            IClusterBuilder clusterBuilder = new ClusterBuilder();

            clusterBuilder.MinimumScore    = 2;
            clusterBuilder.FixedSeparation = 0;
            IList <Cluster> actualOutput = clusterBuilder.BuildClusters(matches);

            IList <Cluster> expectedOutput = new List <Cluster>();
            IList <MaxUniqueMatchExtension> clusterMatches = new List <MaxUniqueMatchExtension>();

            match = new MaxUniqueMatch();
            match.FirstSequenceStart  = 0;
            match.Length              = 4;
            match.SecondSequenceStart = 4;
            clusterMatches.Add(new MaxUniqueMatchExtension(match));
            expectedOutput.Add(new Cluster(clusterMatches));

            clusterMatches            = new List <MaxUniqueMatchExtension>();
            match                     = new MaxUniqueMatch();
            match.FirstSequenceStart  = 4;
            match.Length              = 3;
            match.SecondSequenceStart = 0;
            clusterMatches.Add(new MaxUniqueMatchExtension(match));
            expectedOutput.Add(new Cluster(clusterMatches));

            clusterMatches            = new List <MaxUniqueMatchExtension>();
            match                     = new MaxUniqueMatch();
            match.FirstSequenceStart  = 10;
            match.Length              = 3;
            match.SecondSequenceStart = 10;
            clusterMatches.Add(new MaxUniqueMatchExtension(match));
            expectedOutput.Add(new Cluster(clusterMatches));

            Assert.IsTrue(this.CompareMumList(actualOutput, expectedOutput));
        }
Esempio n. 2
0
        bool ValidateUniqueMatches(IList <Match> matches,
                                   string nodeName, AdditionalParameters additionalParam, bool isFilePath)
        {
            switch (additionalParam)
            {
            case AdditionalParameters.PerformClusterBuilder:
                // Validates the Cluster builder MUMs
                string firstSeqOrderExpected =
                    utilityObj.xmlUtil.GetTextValue(nodeName, Constants.ClustFirstSequenceStartNode);
                string lengthExpected =
                    utilityObj.xmlUtil.GetTextValue(nodeName, Constants.ClustLengthNode);
                string secondSeqOrderExpected =
                    utilityObj.xmlUtil.GetTextValue(nodeName, Constants.ClustSecondSequenceStartNode);

                StringBuilder firstSeqOrderActual  = new StringBuilder();
                StringBuilder lengthActual         = new StringBuilder();
                StringBuilder secondSeqOrderActual = new StringBuilder();

                ClusterBuilder cb = new ClusterBuilder();
                cb.MinimumScore = 0;

                List <MatchExtension> meObj = new List <MatchExtension>();

                foreach (Match m in matches)
                {
                    meObj.Add(new MatchExtension(m));
                }

                // Order the mum list with query sequence order and
                // Assign query sequence to the MUM's
                for (int index = 0; index < meObj.Count(); index++)
                {
                    meObj.ElementAt(index).ReferenceSequenceMumOrder = index + 1;
                    meObj.ElementAt(index).QuerySequenceMumOrder     = index + 1;
                }

                List <Cluster> clusts = cb.BuildClusters(meObj);

                foreach (Cluster clust in clusts)
                {
                    foreach (MatchExtension maxMatchExtension in clust.Matches)
                    {
                        firstSeqOrderActual.Append(maxMatchExtension.ReferenceSequenceMumOrder);
                        secondSeqOrderActual.Append(maxMatchExtension.QuerySequenceMumOrder);
                        lengthActual.Append(maxMatchExtension.Length);
                    }
                }

                if ((0 != string.Compare(firstSeqOrderExpected.Replace(",", ""),
                                         firstSeqOrderActual.ToString(), true, CultureInfo.CurrentCulture)) ||
                    (0 != string.Compare(lengthExpected.Replace(",", ""),
                                         lengthActual.ToString(), true, CultureInfo.CurrentCulture)) ||
                    (0 != string.Compare(secondSeqOrderExpected.Replace(",", ""),
                                         secondSeqOrderActual.ToString(), true, CultureInfo.CurrentCulture)))
                {
                    Console.WriteLine("NUCmer BVT : Unique match not matching");
                    ApplicationLog.WriteLine("NUCmer BVT : Unique match not matching");
                    return(false);
                }
                break;

            case AdditionalParameters.FindUniqueMatches:
                // Gets all the unique matches properties to be validated as in xml.
                string[] firstSeqOrder  = null;
                string[] length         = null;
                string[] secondSeqOrder = null;

                if (isFilePath)
                {
                    firstSeqOrder = utilityObj.xmlUtil.GetFileTextValue(nodeName,
                                                                        Constants.FirstSequenceMumOrderNode).Split(',');
                    length = utilityObj.xmlUtil.GetFileTextValue(nodeName,
                                                                 Constants.LengthNode).Split(',');
                    secondSeqOrder = utilityObj.xmlUtil.GetFileTextValue(nodeName,
                                                                         Constants.SecondSequenceMumOrderNode).Split(',');
                }
                else
                {
                    firstSeqOrder = utilityObj.xmlUtil.GetTextValue(nodeName,
                                                                    Constants.FirstSequenceMumOrderNode).Split(',');
                    length = utilityObj.xmlUtil.GetTextValue(nodeName,
                                                             Constants.LengthNode).Split(',');
                    secondSeqOrder = utilityObj.xmlUtil.GetTextValue(nodeName,
                                                                     Constants.SecondSequenceMumOrderNode).Split(',');
                }

                int i = 0;

                IList <MatchExtension> meNewObj = new List <MatchExtension>();

                foreach (Match m in matches)
                {
                    meNewObj.Add(new MatchExtension(m));
                }

                // Order the mum list with query sequence order and
                // Assign query sequence to the MUM's
                for (int index = 0; index < meNewObj.Count(); index++)
                {
                    meNewObj.ElementAt(index).ReferenceSequenceMumOrder = index + 1;
                    meNewObj.ElementAt(index).QuerySequenceMumOrder     = index + 1;
                }

                // Loops through all the matches and validates the same.
                foreach (MatchExtension match in meNewObj)
                {
                    if ((0 != string.Compare(firstSeqOrder[i],
                                             match.ReferenceSequenceMumOrder.ToString((IFormatProvider)null), true,
                                             CultureInfo.CurrentCulture)) ||
                        (0 != string.Compare(length[i],
                                             match.Length.ToString((IFormatProvider)null), true,
                                             CultureInfo.CurrentCulture)) ||
                        (0 != string.Compare(secondSeqOrder[i],
                                             match.QuerySequenceMumOrder.ToString((IFormatProvider)null), true,
                                             CultureInfo.CurrentCulture)))
                    {
                        Console.WriteLine(string.Format((IFormatProvider)null,
                                                        "NUCmer BVT : Unique match not matching at index '{0}'", i.ToString((IFormatProvider)null)));
                        ApplicationLog.WriteLine(string.Format((IFormatProvider)null,
                                                               "NUCmer BVT : Unique match not matching at index '{0}'", i.ToString((IFormatProvider)null)));
                        return(false);
                    }
                    i++;
                }
                break;

            default:
                break;
            }
            return(true);
        }
Esempio n. 3
0
        /// <summary>
        /// Validates the Unique Matches for the input provided.
        /// </summary>
        /// <param name="matches">Max Unique Match list</param>
        /// <param name="nodeName">Node name to be read from xml</param>
        /// <param name="additionalParam">Unique Match/Sub level LIS/LIS</param>
        /// <param name="isFilePath">Nodes to be read from Text file?</param>
        /// <returns>True, if successfully validated</returns>
        static bool ValidateUniqueMatches(IList <MaxUniqueMatch> matches,
                                          string nodeName, AdditionalParameters additionalParam, bool isFilePath)
        {
            switch (additionalParam)
            {
            case AdditionalParameters.PerformClusterBuilder:
                // Validates the Cluster builder MUMs
                string firstSeqOrderExpected =
                    Utility._xmlUtil.GetTextValue(nodeName, Constants.ClustFirstSequenceMumOrderNode);
                string firstSeqStartExpected =
                    Utility._xmlUtil.GetTextValue(nodeName, Constants.ClustFirstSequenceStartNode);
                string lengthExpected =
                    Utility._xmlUtil.GetTextValue(nodeName, Constants.ClustLengthNode);
                string secondSeqOrderExpected =
                    Utility._xmlUtil.GetTextValue(nodeName, Constants.ClustSecondSequenceMumOrderNode);
                string secondSeqStartExpected =
                    Utility._xmlUtil.GetTextValue(nodeName, Constants.ClustSecondSequenceStartNode);

                StringBuilder firstSeqOrderActual  = new StringBuilder();
                StringBuilder firstSeqStartActual  = new StringBuilder();
                StringBuilder lengthActual         = new StringBuilder();
                StringBuilder secondSeqOrderActual = new StringBuilder();
                StringBuilder secondSeqStartActual = new StringBuilder();

                ClusterBuilder cb = new ClusterBuilder();
                cb.MinimumScore = 0;
                IList <Cluster> clusts = cb.BuildClusters(matches);

                foreach (Cluster clust in clusts)
                {
                    foreach (MaxUniqueMatchExtension maxMatchExtension in clust.Matches)
                    {
                        firstSeqOrderActual.Append(maxMatchExtension.FirstSequenceMumOrder);
                        secondSeqOrderActual.Append(maxMatchExtension.SecondSequenceMumOrder);
                        secondSeqStartActual.Append(maxMatchExtension.SecondSequenceStart);
                        firstSeqStartActual.Append(maxMatchExtension.FirstSequenceStart);
                        lengthActual.Append(maxMatchExtension.Length);
                    }
                }

                if ((0 != string.Compare(firstSeqOrderExpected.Replace(",", ""),
                                         firstSeqOrderActual.ToString(), true, CultureInfo.CurrentCulture)) ||
                    (0 != string.Compare(firstSeqStartExpected.Replace(",", ""),
                                         firstSeqStartActual.ToString(), true, CultureInfo.CurrentCulture)) ||
                    (0 != string.Compare(lengthExpected.Replace(",", ""),
                                         lengthActual.ToString(), true, CultureInfo.CurrentCulture)) ||
                    (0 != string.Compare(secondSeqOrderExpected.Replace(",", ""),
                                         secondSeqOrderActual.ToString(), true, CultureInfo.CurrentCulture)) ||
                    (0 != string.Compare(secondSeqStartExpected.Replace(",", ""),
                                         secondSeqStartActual.ToString(), true, CultureInfo.CurrentCulture)))
                {
                    Console.WriteLine("NUCmer BVT : Unique match not matching");
                    ApplicationLog.WriteLine("NUCmer BVT : Unique match not matching");
                    return(false);
                }
                break;

            case AdditionalParameters.FindUniqueMatches:
                // Gets all the unique matches properties to be validated as in xml.
                string[] firstSeqOrder  = null;
                string[] firstSeqStart  = null;
                string[] length         = null;
                string[] secondSeqOrder = null;
                string[] secondSeqStart = null;

                if (isFilePath)
                {
                    firstSeqOrder = Utility._xmlUtil.GetFileTextValue(nodeName,
                                                                      Constants.FirstSequenceMumOrderNode).Split(',');
                    firstSeqStart = Utility._xmlUtil.GetFileTextValue(nodeName,
                                                                      Constants.FirstSequenceStartNode).Split(',');
                    length = Utility._xmlUtil.GetFileTextValue(nodeName,
                                                               Constants.LengthNode).Split(',');
                    secondSeqOrder = Utility._xmlUtil.GetFileTextValue(nodeName,
                                                                       Constants.SecondSequenceMumOrderNode).Split(',');
                    secondSeqStart = Utility._xmlUtil.GetFileTextValue(nodeName,
                                                                       Constants.SecondSequenceStartNode).Split(',');
                }
                else
                {
                    firstSeqOrder = Utility._xmlUtil.GetTextValue(nodeName,
                                                                  Constants.FirstSequenceMumOrderNode).Split(',');
                    firstSeqStart = Utility._xmlUtil.GetTextValue(nodeName,
                                                                  Constants.FirstSequenceStartNode).Split(',');
                    length = Utility._xmlUtil.GetTextValue(nodeName,
                                                           Constants.LengthNode).Split(',');
                    secondSeqOrder = Utility._xmlUtil.GetTextValue(nodeName,
                                                                   Constants.SecondSequenceMumOrderNode).Split(',');
                    secondSeqStart = Utility._xmlUtil.GetTextValue(nodeName,
                                                                   Constants.SecondSequenceStartNode).Split(',');
                }

                int i = 0;
                // Loops through all the matches and validates the same.
                foreach (MaxUniqueMatch match in matches)
                {
                    if ((0 != string.Compare(firstSeqOrder[i],
                                             match.FirstSequenceMumOrder.ToString((IFormatProvider)null), true,
                                             CultureInfo.CurrentCulture)) ||
                        (0 != string.Compare(firstSeqStart[i],
                                             match.FirstSequenceStart.ToString((IFormatProvider)null), true,
                                             CultureInfo.CurrentCulture)) ||
                        (0 != string.Compare(length[i],
                                             match.Length.ToString((IFormatProvider)null), true,
                                             CultureInfo.CurrentCulture)) ||
                        (0 != string.Compare(secondSeqOrder[i],
                                             match.SecondSequenceMumOrder.ToString((IFormatProvider)null), true,
                                             CultureInfo.CurrentCulture)) ||
                        (0 != string.Compare(secondSeqStart[i],
                                             match.SecondSequenceStart.ToString((IFormatProvider)null), true,
                                             CultureInfo.CurrentCulture)))
                    {
                        Console.WriteLine(string.Format(null,
                                                        "NUCmer BVT : Unique match not matching at index '{0}'", i.ToString()));
                        ApplicationLog.WriteLine(string.Format(null,
                                                               "NUCmer BVT : Unique match not matching at index '{0}'", i.ToString()));
                        return(false);
                    }
                    i++;
                }
                break;

            default:
                break;
            }
            return(true);
        }