public static LSEResult GetResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromEvaluation)
{
LSEResult result = new LSEResult();
YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId);
if (panelSetOrderLynchSyndromeIHC != null)
{
panelSetOrderLynchSyndromeIHC.SetSummaryResult(result);
}
if (panelSetOrderLynchSyndromEvaluation.BRAFIsIndicated == true)
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest brafV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
if (accessionOrder.PanelSetOrderCollection.Exists(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true);
panelSetOrderBraf.SetSummaryResult(result);
}
}
YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis panelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true);
panelSetOrderMLH1MethylationAnalysis.SetSummaryResult(result);
}
return(result);
}
public LSEResultStatus(LSEResult lseResult, YellowstonePathology.Business.Test.AccessionOrder accessionOrder, string orderedOnId)
{
this.m_LSEResult = lseResult;
this.m_AccessionOrder = accessionOrder;
this.m_OrderedOnId = orderedOnId;
this.m_LSEResultList = new List<LSEResult>();
}
public void SetSummaryResult(LSEResult lSEResult)
{
IHCResult result = IHCResult.CreateResultFromResultCode(this.m_ResultCode);
if (result != null)
{
lSEResult.MLH1Result = result.MLH1Result.LSEResult;
lSEResult.MSH2Result = result.MSH2Result.LSEResult;
lSEResult.MSH6Result = result.MSH6Result.LSEResult;
lSEResult.PMS2Result = result.PMS2Result.LSEResult;
}
}
public LSEResultStatusMethylationAnalysisRequired(LSEResult lseResult, YellowstonePathology.Business.Test.AccessionOrder accessionOrder)
: base(lseResult, accessionOrder)
{
LSEResult result1 = new LSEResult();
result1.MLH1Result = LSEResultEnum.Negative;
result1.MSH2Result = LSEResultEnum.Positive;
result1.MSH6Result = LSEResultEnum.Positive;
result1.PMS2Result = LSEResultEnum.Negative;
result1.BrafResult = LSEResultEnum.Negative;
this.m_LSEResultList.Add(result1);
LSEResult result2 = new LSEResult();
result2.MLH1Result = LSEResultEnum.Negative;
result2.MSH2Result = LSEResultEnum.Positive;
result2.MSH6Result = LSEResultEnum.Positive;
result2.MSH6Result = LSEResultEnum.Positive;
result2.BrafResult = LSEResultEnum.Negative;
this.m_LSEResultList.Add(result2);
if (this.IsMatch() == true)
{
this.m_IsMatch = true;
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(144) == true || this.m_AccessionOrder.PanelSetOrderCollection.Exists(64) == true)
{
YellowstonePathology.Business.Test.PanelSetOrder panelSetOrder = this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(144);
if (panelSetOrder == null)
{
panelSetOrder = this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(64);
}
if (panelSetOrder.Final == true)
{
this.m_Status = "LSE is complete.";
this.m_IsOrdered = true;
}
else
{
this.m_Status = "Methylation Analysis testing is required and has been ordered.";
this.m_IsOrdered = true;
}
}
else
{
this.m_Status = "Methylation Analysis Testing is required and should be ordered.";
this.m_IsOrdered = false;
}
}
}
public LSEResultStatusCompleteAfterMSI(LSEResult lseResult, YellowstonePathology.Business.Test.AccessionOrder accessionOrder)
: base(lseResult, accessionOrder)
{
LSEResult result1 = new LSEResult();
result1.MLH1Result = LSEResultEnum.Positive;
result1.MSH2Result = LSEResultEnum.Positive;
result1.MSH6Result = LSEResultEnum.Positive;
result1.PMS2Result = LSEResultEnum.Positive;
m_LSEResultList.Add(result1);
LSEResult result2 = new LSEResult();
result2.MLH1Result = LSEResultEnum.Positive;
result2.MSH2Result = LSEResultEnum.Negative;
result2.MSH6Result = LSEResultEnum.Negative;
result2.PMS2Result = LSEResultEnum.Positive;
m_LSEResultList.Add(result2);
LSEResult result3 = new LSEResult();
result3.MLH1Result = LSEResultEnum.Positive;
result3.MSH2Result = LSEResultEnum.Negative;
result3.MSH6Result = LSEResultEnum.Positive;
result3.PMS2Result = LSEResultEnum.Positive;
m_LSEResultList.Add(result3);
LSEResult result4 = new LSEResult();
result4.MLH1Result = LSEResultEnum.Positive;
result4.MSH2Result = LSEResultEnum.Positive;
result4.MSH6Result = LSEResultEnum.Negative;
result4.PMS2Result = LSEResultEnum.Positive;
m_LSEResultList.Add(result4);
LSEResult result5 = new LSEResult();
result5.MLH1Result = LSEResultEnum.Positive;
result5.MSH2Result = LSEResultEnum.Positive;
result5.MSH6Result = LSEResultEnum.Positive;
result5.PMS2Result = LSEResultEnum.Negative;
m_LSEResultList.Add(result5);
if (this.IsMatch() == true)
{
this.m_IsMatch = true;
this.m_IsOrdered = true;
this.m_Status = "No further testing is required.";
}
}
public LSEResultStatusMethylationAnalysisRequired(LSEResult lseResult, YellowstonePathology.Business.Test.AccessionOrder accessionOrder)
: base(lseResult, accessionOrder)
{
LSEResult result1 = new LSEResult();
result1.MLH1Result = LSEResultEnum.Negative;
result1.MSH2Result = LSEResultEnum.Positive;
result1.MSH6Result = LSEResultEnum.Positive;
result1.PMS2Result = LSEResultEnum.Negative;
result1.BrafResult = LSEResultEnum.Negative;
this.m_LSEResultList.Add(result1);
LSEResult result2 = new LSEResult();
result2.MLH1Result = LSEResultEnum.Negative;
result2.MSH2Result = LSEResultEnum.Positive;
result2.MSH6Result = LSEResultEnum.Positive;
result2.MSH6Result = LSEResultEnum.Positive;
result2.BrafResult = LSEResultEnum.Negative;
this.m_LSEResultList.Add(result2);
if (this.IsMatch() == true)
{
this.m_IsMatch = true;
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(144) == true || this.m_AccessionOrder.PanelSetOrderCollection.Exists(64) == true)
{
YellowstonePathology.Business.Test.PanelSetOrder panelSetOrder = this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(144);
if (panelSetOrder == null) panelSetOrder = this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(64);
if (panelSetOrder.Final == true)
{
this.m_Status = "LSE is complete.";
this.m_IsOrdered = true;
}
else
{
this.m_Status = "Methylation Analysis testing is required and has been ordered.";
this.m_IsOrdered = true;
}
}
else
{
this.m_Status = "Methylation Analysis Testing is required and should be ordered.";
this.m_IsOrdered = false;
}
}
}
public LSEResultStatusCompleteAfterMSI(LSEResult lseResult, YellowstonePathology.Business.Test.AccessionOrder accessionOrder, string orderedOnId)
: base(lseResult, accessionOrder, orderedOnId)
{
LSEResult result1 = new LSEResult();
result1.MLH1Result = LSEResultEnum.Intact;
result1.MSH2Result = LSEResultEnum.Intact;
result1.MSH6Result = LSEResultEnum.Intact;
result1.PMS2Result = LSEResultEnum.Intact;
m_LSEResultList.Add(result1);
LSEResult result2 = new LSEResult();
result2.MLH1Result = LSEResultEnum.Intact;
result2.MSH2Result = LSEResultEnum.Loss;
result2.MSH6Result = LSEResultEnum.Loss;
result2.PMS2Result = LSEResultEnum.Intact;
m_LSEResultList.Add(result2);
LSEResult result3 = new LSEResult();
result3.MLH1Result = LSEResultEnum.Intact;
result3.MSH2Result = LSEResultEnum.Loss;
result3.MSH6Result = LSEResultEnum.Intact;
result3.PMS2Result = LSEResultEnum.Intact;
m_LSEResultList.Add(result3);
LSEResult result4 = new LSEResult();
result4.MLH1Result = LSEResultEnum.Intact;
result4.MSH2Result = LSEResultEnum.Intact;
result4.MSH6Result = LSEResultEnum.Loss;
result4.PMS2Result = LSEResultEnum.Intact;
m_LSEResultList.Add(result4);
LSEResult result5 = new LSEResult();
result5.MLH1Result = LSEResultEnum.Intact;
result5.MSH2Result = LSEResultEnum.Intact;
result5.MSH6Result = LSEResultEnum.Intact;
result5.PMS2Result = LSEResultEnum.Loss;
m_LSEResultList.Add(result5);
if (this.IsMatch() == true)
{
this.m_IsMatch = true;
this.m_IsOrdered = true;
this.m_Status = "No further testing is required.";
}
}
public LSEResultStatusBRAFRequired(LSEResult lseResult, YellowstonePathology.Business.Test.AccessionOrder accessionOrder, string orderedOnId)
: base(lseResult, accessionOrder, orderedOnId)
{
LSEResult result1 = new LSEResult();
result1.MLH1Result = LSEResultEnum.Loss;
result1.MSH2Result = LSEResultEnum.Intact;
result1.MSH6Result = LSEResultEnum.Intact;
result1.PMS2Result = LSEResultEnum.Loss;
m_LSEResultList.Add(result1);
LSEResult result2 = new LSEResult();
result2.MLH1Result = LSEResultEnum.Loss;
result2.MSH2Result = LSEResultEnum.Intact;
result2.MSH6Result = LSEResultEnum.Intact;
result2.PMS2Result = LSEResultEnum.Intact;
m_LSEResultList.Add(result2);
if (this.IsMatch() == true)
{
this.m_IsMatch = true;
if (accessionOrder.PanelSetOrderCollection.Exists(18, orderedOnId, true) ||
accessionOrder.PanelSetOrderCollection.Exists(30, orderedOnId, true) == true)
{
YellowstonePathology.Business.Test.PanelSetOrder panelSetOrder = this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(30, orderedOnId, true);
if (panelSetOrder == null) panelSetOrder = this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(18, orderedOnId, true);
if (panelSetOrder.Final == true)
{
this.m_IsOrdered = true;
this.m_Status = "LSE Complete.";
}
else
{
this.m_IsOrdered = true;
this.m_Status = "BRAF testing is required and has been ordered.";
}
}
else
{
this.m_IsOrdered = false;
this.m_Status = "BRAF Testing is required and should be ordered.";
}
}
}
public void SetSummaryResult(LSEResult lSEResult)
{
if (string.IsNullOrEmpty(m_Result) == false)
{
MLH1MethylationAnalysisDetectedResult detected = new MLH1MethylationAnalysisDetectedResult();
MLH1MethylationAnalysisNotDetectedResult notDetected = new MLH1MethylationAnalysisNotDetectedResult();
if (this.ResultCode == detected.ResultCode)
{
lSEResult.MethResult = LSEResultEnum.Positive;
}
else if (this.ResultCode == notDetected.ResultCode)
{
lSEResult.MethResult = LSEResultEnum.Negative;
}
}
else
{
lSEResult.MethResult = LSEResultEnum.Pending;
}
}
public LSEResultStatusMethylationAnalysisRequiredGYN(LSEResult lseResult, YellowstonePathology.Business.Test.AccessionOrder accessionOrder, string orderedOnId)
: base(lseResult, accessionOrder, orderedOnId)
{
LSEResult result1 = new LSEResult();
result1.MLH1Result = LSEResultEnum.Negative;
m_LSEResultList.Add(result1);
if (this.IsMatch() == true)
{
this.m_IsMatch = true;
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(64, orderedOnId, true) == true || this.m_AccessionOrder.PanelSetOrderCollection.Exists(144, orderedOnId, true))
{
this.m_Status = "Methylation Analysis testing is required and has been ordered.";
this.m_IsOrdered = true;
}
else
{
this.m_Status = "Methylation Analysis Testing is required and should be ordered.";
this.m_IsOrdered = false;
}
}
}
public LSEResultStatusMethylationAnalysisRequiredGYN(LSEResult lseResult, YellowstonePathology.Business.Test.AccessionOrder accessionOrder)
: base(lseResult, accessionOrder)
{
LSEResult result1 = new LSEResult();
result1.MLH1Result = LSEResultEnum.Negative;
m_LSEResultList.Add(result1);
if (this.IsMatch() == true)
{
this.m_IsMatch = true;
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(64) == true || this.m_AccessionOrder.PanelSetOrderCollection.Exists(144))
{
this.m_Status = "Methylation Analysis testing is required and has been ordered.";
this.m_IsOrdered = true;
}
else
{
this.m_Status = "Methylation Analysis Testing is required and should be ordered.";
this.m_IsOrdered = false;
}
}
}
public void SetSummaryResult(LSEResult lSEResult)
{
if (string.IsNullOrEmpty(m_Result) == false)
{
MLH1MethylationAnalysisDetectedResult detected = new MLH1MethylationAnalysisDetectedResult();
MLH1MethylationAnalysisNotDetectedResult notDetected = new MLH1MethylationAnalysisNotDetectedResult();
if (this.ResultCode == detected.ResultCode)
{
lSEResult.MethResult = LSEResultEnum.Positive;
}
else if (this.ResultCode == notDetected.ResultCode)
{
lSEResult.MethResult = LSEResultEnum.Negative;
}
}
else
{
lSEResult.MethResult = LSEResultEnum.Pending;
}
}
public LSEResultStatus(LSEResult lseResult, YellowstonePathology.Business.Test.AccessionOrder accessionOrder)
{
this.m_LSEResult = lseResult;
this.m_AccessionOrder = accessionOrder;
this.m_LSEResultList = new List <LSEResult>();
}
public static LSEResult GetResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromEvaluation)
{
LSEResult result = new LSEResult();
YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true);
if (panelSetOrderLynchSyndromeIHC != null) panelSetOrderLynchSyndromeIHC.SetSummaryResult(result);
if (panelSetOrderLynchSyndromEvaluation.BRAFIsIndicated == true)
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest brafV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTest rasRAFPanelTest = new YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTest();
if (accessionOrder.PanelSetOrderCollection.Exists(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true);
panelSetOrderBraf.SetSummaryResult(result);
}
else if(accessionOrder.PanelSetOrderCollection.Exists(rasRAFPanelTest.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTestOrder panelSetOrderRASRAF = (YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(rasRAFPanelTest.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true);
panelSetOrderRASRAF.SetBrafSummaryResult(result);
}
}
YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis panelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true);
panelSetOrderMLH1MethylationAnalysis.SetSummaryResult(result);
}
return result;
}
public LSEResultStatusNotSet(LSEResult lseResult, YellowstonePathology.Business.Test.AccessionOrder accessionOrder)
: base(lseResult, accessionOrder)
{
this.m_IsOrdered = false;
this.m_Status = "The LSE Type must be set before a status can be set.";
}
public void SetSummaryResult(LSEResult lSEResult)
{
IHCResult result = IHCResult.CreateResultFromResultCode(this.m_ResultCode);
if (result != null)
{
lSEResult.MLH1Result = result.MLH1Result.LSEResult;
lSEResult.MSH2Result = result.MSH2Result.LSEResult;
lSEResult.MSH6Result = result.MSH6Result.LSEResult;
lSEResult.PMS2Result = result.PMS2Result.LSEResult;
}
}
public LSEResultStatusNotSet(LSEResult lseResult, YellowstonePathology.Business.Test.AccessionOrder accessionOrder, string orderedOnId)
: base(lseResult, accessionOrder, orderedOnId)
{
this.m_IsOrdered = false;
this.m_Status = "The LSE Type must be set before a status can be set.";
}