public void Validate(IEnumerable <IsobaricItem> items)
{
List <double> logratio = new List <double>();
foreach (var item in items)
{
var r1 = refFunc1.GetValue(item);
var r2 = refFunc2.GetValue(item);
item.Valid = r1 > ITraqConsts.NULL_INTENSITY && r2 > ITraqConsts.NULL_INTENSITY;
if (item.Valid)
{
logratio.Add(Math.Log(r1 / r2));
}
}
if (logratio.Count > 1)
{
MeanStandardDeviation acc = new MeanStandardDeviation(logratio);
var nd = new Normal(acc.Mean, acc.StdDev);
foreach (var item in items)
{
if (item.Valid)
{
var r1 = refFunc1.GetValue(item);
var r2 = refFunc2.GetValue(item);
var logr = Math.Log(r1 / r2);
item.ValidProbability = nd.TwoTailProbability(logr);
item.Valid = item.ValidProbability >= minProbability;
}
}
}
}
public void Validate(IEnumerable <IsobaricItem> items)
{
foreach (var item in items)
{
item.Valid = refFunc.GetValue(item) > ITraqConsts.NULL_INTENSITY;
}
}