public void FillTablesAndCharts()
{
DisplayUtility.FillDataGridView(dgv_fileList, Sweet.lollipop.get_files(Sweet.lollipop.input_files, new Purpose[] { Purpose.Identification, Purpose.Quantification }).Select(c => new DisplayInputFile(c)));
DisplayInputFile.FormatInputFileTable(dgv_fileList, new Purpose[] { Purpose.Identification, Purpose.Quantification });
dgv_fileList.ReadOnly = true;
if (rb_displayIdentificationComponents.IsChecked.HasValue && (bool)rb_displayIdentificationComponents.IsChecked.Value && Sweet.lollipop.raw_experimental_components.Count > 0)
{
DisplayUtility.FillDataGridView(dgv_rawComponents, Sweet.lollipop.raw_experimental_components.Select(c => new DisplayComponent(c)));
}
if (rb_displayQuantificationComponents.IsChecked.HasValue && (bool)rb_displayQuantificationComponents.IsChecked.Value && Sweet.lollipop.raw_quantification_components.Count > 0)
{
DisplayUtility.FillDataGridView(dgv_rawComponents, Sweet.lollipop.raw_quantification_components.Select(c => new DisplayComponent(c)));
}
DisplayComponent.FormatComponentsTable(dgv_rawComponents);
rtb_raw_components_counts.Text = ResultsSummaryGenerator.raw_components_report();
NeuCodePairs pairs_form = this.MDIParent.neuCodePairs;
if (Sweet.lollipop.neucode_labeled && pairs_form.ReadyToRunTheGamut())
{
pairs_form.RunTheGamut(false);
}
}
private void neuCodeProteoformPairsToolStripMenuItem_Click(object sender, EventArgs e)
{
showForm(neuCodePairs);
if (neuCodePairs.ReadyToRunTheGamut())
{
neuCodePairs.RunTheGamut(false); // There's no update/run button in NeuCodePairs, so just fill the tables
}
}
private void Btn_RunPage_Click(object sender, RoutedEventArgs e)
{
ClosingTabItem item = MDIContainer.SelectedValue as ClosingTabItem;
// MessageBox.Show("This page is :" + item.Title);
// Dynamically change the button's action according to page.
// i.e. use the correct RunTheGamut that refers to page.
switch (item.Title)
{
case "Load Results":
// not yet
break;
case "Theoretical Database":
Mouse.OverrideCursor = Cursors.Wait;
theoreticalDatabase.RunTheGamut(false);
Mouse.OverrideCursor = null;
break;
case "Top Down":
topDown.RunTheGamut(false);
break;
case "Raw Experimental Components":
Mouse.OverrideCursor = Cursors.Wait;
rawExperimentalComponents.RunTheGamut(false);
Mouse.OverrideCursor = null;
break;
case "Neu Code Pairs":
if (neuCodePairs.ReadyToRunTheGamut())
{
neuCodePairs.RunTheGamut(false);
}
break;
case "Aggregated Proteoforms":
if (aggregatedProteoforms.ReadyToRunTheGamut())
{
Mouse.OverrideCursor = Cursors.Wait;
aggregatedProteoforms.RunTheGamut(false);
Mouse.OverrideCursor = null;
}
else if (Sweet.lollipop.target_proteoform_community.experimental_proteoforms.Length <= 0)
{
MessageBox.Show("Go back and load in deconvolution results.");
}
break;
case "Experiment Theoretical Comparison":
if (experimentTheoreticalComparison.ReadyToRunTheGamut())
{
System.Windows.Input.Mouse.OverrideCursor = System.Windows.Input.Cursors.Wait;
experimentTheoreticalComparison.RunTheGamut(false);
experimentTheoreticalComparison.xMaxET.Value = (decimal)Sweet.lollipop.et_high_mass_difference;
experimentTheoreticalComparison.xMinET.Value = (decimal)Sweet.lollipop.et_low_mass_difference;
System.Windows.Input.Mouse.OverrideCursor = null;
}
else if (Sweet.lollipop.target_proteoform_community.has_e_proteoforms)
{
MessageBox.Show("Go back and create a theoretical database.");
}
else
{
MessageBox.Show("Go back and aggregate experimental proteoforms.");
}
break;
case "Experiment Experiment Comparison":
if (experimentExperimentComparison.ReadyToRunTheGamut())
{
System.Windows.Input.Mouse.OverrideCursor = System.Windows.Input.Cursors.Wait;
experimentExperimentComparison.RunTheGamut(false);
experimentExperimentComparison.xMaxEE.Value = Convert.ToDecimal(Sweet.lollipop.ee_max_mass_difference);
System.Windows.Input.Mouse.OverrideCursor = null;
}
else if (Sweet.lollipop.target_proteoform_community.has_e_proteoforms)
{
MessageBox.Show("Go back and create the theoretical database.");
}
else
{
MessageBox.Show("Go back and aggregate experimental proteoforms.");
}
break;
case "Proteoform Families":
if (proteoformFamilies.ReadyToRunTheGamut())
{
System.Windows.Input.Mouse.OverrideCursor = System.Windows.Input.Cursors.Wait;
proteoformFamilies.RunTheGamut(false);
System.Windows.Input.Mouse.OverrideCursor = null;
}
break;
case "Identified Proteoforms":
if (identifiedProteoforms.ReadyToRunTheGamut())
{
identifiedProteoforms.RunTheGamut(false);
}
break;
case "Quantification":
if (quantification.ReadyToRunTheGamut())
{
Mouse.OverrideCursor = Cursors.Wait;
quantification.RunTheGamut(false);
Mouse.OverrideCursor = null;
}
else if (Sweet.lollipop.get_files(Sweet.lollipop.input_files, Purpose.Quantification).Count() <= 0)
{
MessageBox.Show("Please load quantification results in Load Deconvolution Results.", "Quantification");
}
else if (Sweet.lollipop.input_files.Where(f => f.purpose == Purpose.Quantification).Where(f => f.purpose == Purpose.Quantification).Any(f => f.fraction == "" || f.biological_replicate == "" || f.technical_replicate == "" || f.lt_condition == ""))
{
MessageBox.Show("Please be sure the technical replicate, fraction, biological replicate, and condition are labeled for each quantification file.");
}
else if (Sweet.lollipop.input_files.Where(f => f.purpose == Purpose.Quantification).Where(f => f.purpose == Purpose.Quantification).Select(f => f.lt_condition).Concat(Sweet.lollipop.input_files.Where(f => f.purpose == Purpose.Quantification).Select(f => Sweet.lollipop.neucode_labeled ? f.hv_condition : f.lt_condition)).Distinct().Count() != 2)
{
MessageBox.Show("Please be sure there are two conditions.");
}
else if (!Sweet.lollipop.neucode_labeled && !Sweet.lollipop.input_files.Where(f => f.purpose == Purpose.Quantification).Select(f => f.lt_condition).Distinct().All(c => Sweet.lollipop.input_files.Where(f => f.purpose == Purpose.Quantification && f.lt_condition == c).Select(f => f.biological_replicate + f.fraction + f.technical_replicate).Distinct().All(d => Sweet.lollipop.input_files.Where(f2 => f2.purpose == Purpose.Quantification && f2.lt_condition != c).
Select(f2 => f2.biological_replicate + f2.fraction + f2.technical_replicate).Distinct().ToList().Contains(d))))
{
MessageBox.Show("Please be sure there are the same number and labels for each biological replicate, fraction, and technical replicate for each condition.");
}
else if (!Sweet.lollipop.input_files.Where(f => f.purpose == Purpose.Quantification).Select(f => f.lt_condition).Concat(Sweet.lollipop.input_files.Where(f => f.purpose == Purpose.Quantification).Select(f => Sweet.lollipop.neucode_labeled ? f.hv_condition : f.lt_condition)).Distinct().All(c => Sweet.lollipop.input_files.Where(f => f.purpose == Purpose.Quantification && f.lt_condition == c).Select(f => f.biological_replicate).Distinct().Count() >= 2))
{
MessageBox.Show("Please be sure there are at least two biological replicates for each condition.");
}
else if (Sweet.lollipop.raw_quantification_components.Count == 0)
{
MessageBox.Show("Please process raw components.", "Quantification");
}
else if (Sweet.lollipop.raw_experimental_components.Count <= 0)
{
MessageBox.Show("Please load deconvolution results.", "Quantification");
}
else if (Sweet.lollipop.target_proteoform_community.experimental_proteoforms.Length <= 0)
{
MessageBox.Show("Please aggregate proteoform observations.", "Quantification");
}
else if (Sweet.lollipop.target_proteoform_community.families.Count <= 0)
{
MessageBox.Show("Please construct proteoform families.", "Quantification");
}
break;
case "Results Summary":
// not yet
break;
default:
MessageBox.Show("ERROR: Click unknown. You clicked: " + item.Title);
break;
}
}