Exemple #1
0
        [TestCase(3, @"\\proto-2\UnitTest_Files\InformedProteomics_TestFiles\MSPathFinderT\ID_005133_8491EFA2.fasta", 323719193)]  // 3MB
        //[TestCase(6, @"\\proto-2\UnitTest_Files\InformedProteomics_TestFiles\MSPathFinderT\ID_004530_B63BD900.fasta", 595227563)]  // 6MB
        //[TestCase(15, @"\\proto-2\UnitTest_Files\InformedProteomics_TestFiles\MSPathFinderT\ID_004208_295531A4.fasta", 1882434687)]  // 15MB
        public void TestSequenceEnumeration(double size, string dbFile, int expected)
        {
            var methodName = MethodBase.GetCurrentMethod().Name;
            TestUtils.ShowStarting(methodName, dbFile);

            var sw = new System.Diagnostics.Stopwatch();
            sw.Start();

            var db = new FastaDatabase(dbFile);
            var indexedDb = new IndexedDatabase(db);
            var numSequences = 0L;
            var timeDB = sw.Elapsed;
            Console.WriteLine("Read DB in " + timeDB.TotalSeconds + " Seconds");
            var estimatedAnnOff = indexedDb.EstimateTotalPeptides(0, 30, 250);
            var timeEstimate = sw.Elapsed;
            Console.WriteLine("Read Estimate in " + (timeEstimate - timeDB).TotalSeconds + " Seconds");
            //int coreCount = 0;
            //foreach (var item in new System.Management.ManagementObjectSearcher("Select NumberOfCores from Win32_Processor").Get())
            //{
            //    coreCount += int.Parse(item["NumberOfCores"].ToString());
            //}
            //Console.WriteLine("Number Of Cores: {0}", coreCount);
            //Console.WriteLine("Processors: " + System.Environment.ProcessorCount);
            Console.WriteLine("Estimated results: " + estimatedAnnOff);
            var annotationsAndOffsets = indexedDb.AnnotationsAndOffsetsNoEnzymeParallel(30, 250);
            var timeGetAnn = sw.Elapsed;
            Console.WriteLine("Read Annotations in " + (timeGetAnn - timeEstimate).TotalSeconds + " Seconds");
            /*/Parallel.ForEach(
                annotationsAndOffsets,
                //                new ParallelOptions { MaxDegreeOfParallelism = 2},
                annotationAndOffset =>
                {
                    Interlocked.Increment(ref numSequences);
                    //++numSequences;
                }
                );/**/
            //annotationsAndOffsets.Select(annotationsAndOffset => annotationsAndOffset.)
            // Below, original: 110, 109(total) seconds
            // Parallelizing AnnotationsAndOffsetsNoEnzyme: 86 seconds
            // Parallelizing AnnotationsAndOffsetsNoEnzyme, yield returns: 79.6, 94, 60, 60 seconds
            //
            // 3MB
            // serial: 
            // Parallel2: 107, 
            //
            // 6MB
            // serial: 
            // Parallel2: 
            //
            // 15MB
            // serial: 
            // Parallel2: 
            //using (var ofstream = new FileStream(Path.Combine(@"F:\InformedProteomicsTestFiles", Path.GetFileNameWithoutExtension(dbFile) + "_par.txt"), FileMode.Create))
            //using (var fout = new StreamWriter(ofstream))
            //{
            //    foreach (var annOff in annotationsAndOffsets)
            //    {
            //        numSequences++;
            //        fout.WriteLine(annOff.Annotation);
            //    }
            //}
            numSequences = annotationsAndOffsets.Count();
            var timeParForEach = sw.Elapsed;
            Console.WriteLine("Parallel ForEach in " + (timeParForEach - timeGetAnn).TotalSeconds + " Seconds");

            Console.WriteLine("NumPeptides: {0}", numSequences);
            sw.Stop();

            Console.WriteLine(@"{0:f4} sec", sw.Elapsed.TotalSeconds);
            //Assert.AreEqual(188961836, numSequences);
            Assert.AreEqual(expected, numSequences);
        }
Exemple #2
0
        private IEnumerable<AnnotationAndOffset> GetAnnotationsAndOffsets(FastaDatabase database, out long estimatedProteins, CancellationToken? cancellationToken = null)
        {
            var indexedDb = new IndexedDatabase(database);
            indexedDb.Read();
            estimatedProteins = indexedDb.EstimateTotalPeptides(SearchMode, MinSequenceLength, MaxSequenceLength, MaxNumNTermCleavages, MaxNumCTermCleavages);
            IEnumerable<AnnotationAndOffset> annotationsAndOffsets;
            if (SearchMode == InternalCleavageType.MultipleInternalCleavages)
            {
                //annotationsAndOffsets = indexedDb.AnnotationsAndOffsetsNoEnzyme(MinSequenceLength, MaxSequenceLength);
                annotationsAndOffsets = indexedDb.AnnotationsAndOffsetsNoEnzymeParallel(MinSequenceLength, MaxSequenceLength, MaxNumThreads, cancellationToken);
            }
            else if (SearchMode == InternalCleavageType.NoInternalCleavage)
            {
                annotationsAndOffsets = indexedDb.IntactSequenceAnnotationsAndOffsets(MinSequenceLength, MaxSequenceLength, MaxNumCTermCleavages);
            }
            else
            {
                annotationsAndOffsets = indexedDb
                    .SequenceAnnotationsAndOffsetsWithNtermOrCtermCleavageNoLargerThan(
                        MinSequenceLength, MaxSequenceLength, MaxNumNTermCleavages, MaxNumCTermCleavages);
            }

            return annotationsAndOffsets;
        }