public CompressedSequenceWriter(Stream stream, IReadOnlyCollection <ReferenceMetadata> referenceMetadataList,
ISerializable genomeCytobands, GenomeAssembly genomeAssembly)
{
_stream = stream;
_writer = new ExtendedBinaryWriter(_stream);
_refSeqNames = new List <string>();
_refSeqIndex = new List <SequenceIndexEntry>();
_twoBitSequence = new TwoBitSequence();
_sequenceCompressor = new SequenceCompressor();
_refSeqMaskedIntervals = new List <List <MaskedEntry> >();
WriteHeader(referenceMetadataList, genomeCytobands, genomeAssembly);
}
private void Dispose(bool disposing)
{
if (disposing)
{
WriteReferenceSequenceIndex();
WriteMaskedIntervals();
WriteEofTag();
_stream.Dispose();
}
_refSeqIndex = null;
_refSeqMaskedIntervals = null;
_twoBitSequence = null;
_sequenceCompressor = null;
_headerDataOffset = 0L;
_indexOffset = 0L;
_maskedIntervalsOffset = 0L;
}