public MSAmandaSearchWrapper() { Settings = new MSAmandaSettings(); helper = new MSHelper(); helper.InitLogWriter(_baseDir.DirPath); helper.SearchProgressChanged += Helper_SearchProgressChanged; var folderForMappings = Path.Combine(_baseDir.DirPath, AmandaMap); // creates dir if not existing Directory.CreateDirectory(folderForMappings); mzID = new OutputMzid(folderForMappings); AvailableSettings = new SettingsFile(helper, Settings, mzID); AvailableSettings.AllEnzymes = new List <MSAmandaEnzyme>(); AvailableSettings.AllModifications = new List <Modification>(); using (var d = new CurrentDirectorySetter(Path.GetDirectoryName(Assembly.GetExecutingAssembly().Location))) { if (!AvailableSettings.ParseEnzymeFile(ENZYME_FILENAME, "", AvailableSettings.AllEnzymes)) { throw new Exception(string.Format(Resources.DdaSearch_MSAmandaSearchWrapper_enzymes_file__0__not_found, ENZYME_FILENAME)); } if (!AvailableSettings.ParseUnimodFile(UNIMOD_FILENAME, AvailableSettings.AllModifications)) { throw new Exception(string.Format(Resources.DdaSearch_MSAmandaSearchWrapper_unimod_file__0__not_found, UNIMOD_FILENAME)); } if (!AvailableSettings.ParseOboFiles()) { throw new Exception(Resources.DdaSearch_MSAmandaSearchWrapper_Obo_files_not_found); } if (!AvailableSettings.ReadInstrumentsFile(INSTRUMENTS_FILENAME)) { throw new Exception(string.Format(Resources.DdaSearch_MSAmandaSearchWrapper_Instruments_file_not_found, INSTRUMENTS_FILENAME)); } } AdditionalSettings = new Dictionary <string, Setting> { { MAX_LOADED_PROTEINS_AT_ONCE, new Setting(MAX_LOADED_PROTEINS_AT_ONCE, 100000, 10, int.MaxValue) }, { MAX_LOADED_SPECTRA_AT_ONCE, new Setting(MAX_LOADED_SPECTRA_AT_ONCE, 10000, 100, int.MaxValue) } }; CurrentFile = 0; }