static void ExecuteSingle(List <Antigen> antigens)
{
var sequences = GetSequencesByAntigens(antigens);
var markov = new HiddenMarkovModel(sequences, TypeBioSequence);
markov.Train();
for (int antibodySize = Constants.MIN_SIZE_ANTIBODY; antibodySize <= Constants.MAX_SIZE_ANTIBODY; antibodySize++)
{
var clonalgPR = new ClonalgPR(distance: markov, antigens: antigens, typeBioSequence: TypeBioSequence, antibodySize: antibodySize);
clonalgPR.Execute(maximumIterations: 1000, percentHighAffinity: 0.6, percentLowAffinity: 0.4);
}
ReadAllFiles(antigens.Count());
}
static void ExecuteMultiple(List <List <Antigen> > antigens)
{
for (int index = 0; index < antigens.Count; index++)
{
var _antigens = antigens[index];
var sequences = _antigens.Select(s => s.Sequence).ToList();
var markov = new HiddenMarkovModel(sequences, TypeBioSequence);
markov.Train();
var clonalgPR = new ClonalgPR(distance: markov, antigens: _antigens, typeBioSequence: TypeBioSequence);
clonalgPR.Execute(maximumIterations: 10000, percentHighAffinity: 0.9, percentLowAffinity: 0.1, index);
}
ReadAllFiles(antigens.Count());
}
