public void should_return_IV_values_for_parameters()
{
var vss = _results.PKParameter(_compoundName, CoreConstants.PKAnalysis.VssPlasma);
vss.Value.ShouldBeEqualTo(_peripheralVenousBloodPK["Vss"].Value * _bioaValue);
var vdplasma = _results.PKParameter(_compoundName, CoreConstants.PKAnalysis.VdPlasma);
vdplasma.Value.ShouldBeEqualTo(_peripheralVenousBloodPK["Vd"].Value * _bioaValue);
var totalCL = _results.PKParameter(_compoundName, CoreConstants.PKAnalysis.TotalPlasmaCL);
totalCL.Value.ShouldBeEqualTo(_peripheralVenousBloodPK["CL"].Value * _bioaValue);
}
public void should_have_used_the_peripheral_venous_blood()
{
var vss = _results.PKParameter(_compoundName, CoreConstants.PKAnalysis.VssPlasma);
vss.Value.ShouldBeEqualTo(_peripheralVenousBloodPK["Vss"].Value);
var vdplasma = _results.PKParameter(_compoundName, CoreConstants.PKAnalysis.VdPlasma);
vdplasma.Value.ShouldBeEqualTo(_peripheralVenousBloodPK["Vd"].Value);
var totalCL = _results.PKParameter(_compoundName, CoreConstants.PKAnalysis.TotalPlasmaCL);
totalCL.Value.ShouldBeEqualTo(_peripheralVenousBloodPK["CL"].Value);
}
public void should_have_used_the_venous_blood()
{
var vdplasma = _results.PKParameter(_compoundName, CoreConstants.PKAnalysis.VdPlasma);
vdplasma.ShouldNotBeNull();
vdplasma.Value.ShouldBeEqualTo(_venousBloodPK["Vd"].Value);
}
private void addFractionAbsorbedWarningTo(PKAnalysis pkAnalysis, GlobalPKAnalysis globalPKAnalysis, string moleculeName)
{
var fractionAbsorbed = globalPKAnalysis.PKParameter(moleculeName, CoreConstants.PKAnalysis.FractionAbsorbed);
if (fractionAbsorbed == null)
{
return;
}
if (ValueComparer.AreValuesEqual(fractionAbsorbed.Value, 1, CoreConstants.DOUBLE_RELATIVE_EPSILON))
{
return;
}
addWarningsTo(pkAnalysis, PKSimConstants.Warning.FractionAbsorbedSmallerThanOne, CoreConstants.PKAnalysis.AllParametersInfluencedByFractionAbsorbed);
}
public DataTable MapFrom(GlobalPKAnalysis globalPKAnalysis, bool addMetaData = false)
{
var dataTable = new DataTable(PKSimConstants.UI.GlobalPKAnalyses);
dataTable.AddColumn(PKSimConstants.PKAnalysis.ParameterDisplayName);
dataTable.AddColumn(PKSimConstants.PKAnalysis.Compound);
dataTable.AddColumn <double>(PKSimConstants.PKAnalysis.Value);
dataTable.AddColumn(PKSimConstants.PKAnalysis.Unit);
if (addMetaData)
{
dataTable.AddColumn(PKSimConstants.PKAnalysis.ParameterName);
dataTable.AddColumn(PKSimConstants.PKAnalysis.Description);
dataTable.AddColumn(PKSimConstants.PKAnalysis.Warning);
}
foreach (var parameterName in globalPKAnalysis.AllPKParameterNames)
{
foreach (var compoundName in globalPKAnalysis.CompoundNames)
{
var parameter = globalPKAnalysis.PKParameter(compoundName, parameterName);
if (parameter == null)
{
continue;
}
var info = _representationInfoRepository.InfoFor(parameter);
var row = dataTable.NewRow();
row[PKSimConstants.PKAnalysis.ParameterDisplayName] = info.DisplayName;
row[PKSimConstants.PKAnalysis.Compound] = compoundName;
row[PKSimConstants.PKAnalysis.Value] = parameter.ValueInDisplayUnit;
row[PKSimConstants.PKAnalysis.Unit] = parameter.DisplayUnit;
if (addMetaData)
{
row[PKSimConstants.PKAnalysis.ParameterName] = parameter.Name;
row[PKSimConstants.PKAnalysis.Warning] = parameter.Validate().Message;
row[PKSimConstants.PKAnalysis.Description] = info.Description;
}
dataTable.Rows.Add(row);
}
}
return(dataTable);
}
public void should_not_contain_value_for_fraction_absorbed()
{
_result.PKParameter(_compoundName, CoreConstants.PKAnalysis.FractionAbsorbed).ShouldBeNull();
}
