public void TestIsMutationOneIgnoreDeamidated()
{
int site = -1;
//N->D
Assert.IsTrue(MutationUtils.IsMutationOne2("ABNDEIR", "ABDDEIR", ref site, false, false, false));
//N->D
Assert.IsFalse(MutationUtils.IsMutationOne2("ABNDEIR", "ABDDEIR", ref site, false, true, false));
//Q->E
Assert.IsTrue(MutationUtils.IsMutationOne2("ABQDEIR", "ABEDEIR", ref site, false, false, false));
//Q->E
Assert.IsFalse(MutationUtils.IsMutationOne2("ABQDEIR", "ABEDEIR", ref site, false, true, false));
//N->D
Assert.IsTrue(MutationUtils.IsMutationOneIL2("ABNDEIR", "ABDDELR", ref site, false, false, false));
//N->D
Assert.IsFalse(MutationUtils.IsMutationOneIL2("ABNDEIR", "ABDDELR", ref site, false, true, false));
//Q->E
Assert.IsTrue(MutationUtils.IsMutationOneIL2("ABQDEIR", "ABEDELR", ref site, false, false, false));
//Q->E
Assert.IsFalse(MutationUtils.IsMutationOneIL2("ABQDEIR", "ABEDELR", ref site, false, true, false));
}
public void TestIsMutationOneIgnoreNTerminal()
{
int site = -1;
Assert.IsTrue(MutationUtils.IsMutationOne2("ABCDEIR", "BBCDEIR", ref site, false, false, false));
Assert.IsFalse(MutationUtils.IsMutationOne2("ABCDEIR", "BBCDEIR", ref site, true, false, false));
Assert.IsTrue(MutationUtils.IsMutationOneIL2("ABCDEIR", "BBCDELR", ref site, false, false, false));
Assert.IsTrue(MutationUtils.IsMutationOneIL2("ABCDELR", "BBCDEIR", ref site, false, false, false));
Assert.IsFalse(MutationUtils.IsMutationOneIL2("ABCDELR", "BBCDEIR", ref site, true, false, false));
}
private bool FindMutationOneType1(string pnovoseq, ref string source, ref int site)
{
if (!miss0group.ContainsKey(pnovoseq.Length))
{
return(false);
}
var lst = miss0group[pnovoseq.Length];
foreach (var m in lst)
{
if (MutationUtils.IsMutationOne2(m, pnovoseq, ref site, options.IgnoreNtermMutation, options.IgnoreDeamidatedMutation, options.IgnoreMultipleNucleotideMutation))
{
source = miss0[m];
//Console.WriteLine("TYPE1 : {0} ==> {1}", m, pnovoseq);
return(true);
}
}
return(false);
}